0113 The Influence of Insomnia Severity on Cognitive Functions in Older Surgical Patients Article Swipe
María José Gallardo
,
Aeron Suarez
,
Andrew Charles
,
Elizabeth Sugg
,
Peng Li
,
John O. Hwabejire
,
Harold A. Fogel
,
Stuart H. Hershman
,
John M. Siliski
,
Christopher M. Melnic
,
Kun Hu
,
Lei Gao
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1093/sleep/zsaf090.0113
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1093/sleep/zsaf090.0113
Introduction Sleep disorders, including insomnia, affect up to one-third of older adults over the age of 65 undergoing surgery, yet they often remain untreated. Insomnia-related sleep disturbances have been linked to weakened immune function, delayed recovery, and impaired cognitive abilities (e.g., attention, memory, language), particularly in older adults. However, the influence of sleep-related disorders on cognitive functions in older surgical patients remains unclear. Given the increasing hospitalization rates in older adults, we hypothesized that greater insomnia severity would be associated with poorer cognitive performance. Methods A cohort of 17 older adults (≥70 years) scheduled for total knee, total hip, or spine surgery was recruited. One week before their scheduled surgery, participants were asked to complete the Insomnia Severity Index (ISI) questionnaire and the Montreal Cognitive Assessment (MOCA), which assessed primary cognitive functions, including abstraction, attention, language, orientation, and delayed recall. Results We computed a simple linear regression model analysis to investigate whether ISI scores predicted cognitive performances using the total MOCA scores as our key dependent variables. Additional model predictors were tested included surgery type, sex, and age. In alignment with our hypothesis, results suggested that for every 1 SD increase in ISI scores a 0.09 SD decrease in MOCA scores was predicted (SE =.07, p = 0.26). Although not statistically significant, these preliminary findings are promising, as we are still collecting data and anticipate stronger trends as we reach sufficient statistical power. Conclusion Out preliminary results seemed to indicate that older adults with higher insomnia severity may exhibit larger cognitive impairments, potentially increasing their vulnerability during surgical recovery. Further investigation is warranted. Support (if any) Alzheimer’s Association Clinician Scientist Fellowship (AACSF-23-1148490, L.G)
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- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1093/sleep/zsaf090.0113
- https://academic.oup.com/sleep/article-pdf/48/Supplement_1/A51/63221846/zsaf090.0113.pdf
- OA Status
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- Related Works
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- OpenAlex ID
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All OpenAlex metadata
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https://doi.org/10.1093/sleep/zsaf090.0113Digital Object Identifier
- Title
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0113 The Influence of Insomnia Severity on Cognitive Functions in Older Surgical PatientsWork title
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articleOpenAlex work type
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enPrimary language
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2025Year of publication
- Publication date
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2025-05-01Full publication date if available
- Authors
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María José Gallardo, Aeron Suarez, Andrew Charles, Elizabeth Sugg, Peng Li, John O. Hwabejire, Harold A. Fogel, Stuart H. Hershman, John M. Siliski, Christopher M. Melnic, Kun Hu, Lei GaoList of authors in order
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https://doi.org/10.1093/sleep/zsaf090.0113Publisher landing page
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https://academic.oup.com/sleep/article-pdf/48/Supplement_1/A51/63221846/zsaf090.0113.pdfDirect link to full text PDF
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YesWhether a free full text is available
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bronzeOpen access status per OpenAlex
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https://academic.oup.com/sleep/article-pdf/48/Supplement_1/A51/63221846/zsaf090.0113.pdfDirect OA link when available
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Insomnia, Cognition, Medicine, Psychiatry, Clinical psychology, Psychology, Pediatrics, Physical therapyTop concepts (fields/topics) attached by OpenAlex
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