10109-COT-13 LONG-TERM FOLLOW-UP OF FLAIR HIGH LESION IN THE BRAIN Article Swipe
Shohei Fujita
,
Makoto Ohno
,
Masamichi Takahashi
,
Shunsuke Yanagisawa
,
Sho Osawa
,
Takahiro Tsuchiya
,
Yoshitaka Narita
·
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.1093/noajnl/vdad141.048
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.1093/noajnl/vdad141.048
AIM Incidental FLAIR (Fluid Attenuated Inversion Recovery) high-intensity lesion in the brain can be considered as IDH-mutant low-grade glioma (LGG). Differential diagnosis includes trauma, ischemic changes, demyelinating diseases, and other inflammatory diseases. The biopsy is sometimes high risk for a young patient or an asymptomatic patient with a lesion in the brain stem, motor or language area. Imaging intervals vary among hospitals and the method for regular follow-up for these cases has not been established. METHODS We have studied 26 patients with FLAIR high lesion from 2012 to 2022. In cases of suspected LGG, the biopsy was performed, when necessary, after consultation with the patient and family. Our neurosurgery team protocol was to perform PET-MRI at the first consultation, and if there was negative, we have scheduled MRI examination at the next visit in one month. Then, MRI was performed every 2-3 months for the first year and every 3-6 months thereafter. The clinical features of these FLAIR high lesion and their differentiations from LGG in our cases are examined. RESULTS Biopsy was performed in 5 cases, but no tumor was found. The male-to-female ratio was 7:19, which was more common in female. The median age at onset was 44 years (15-47 years), showing a bimodal distribution with peaks in younger and older individuals. Among 26 cases, 14 cases had been unchanged for more than 5 years. The median maximum lesion diameter was 17 mm (8-47 mm). An annual average increase of LGG has been reported to be 3-5 mm in (Pallud, 2010). There were no cases diagnosed as glioma in cases where no expansion was seen after 5 years or more. CONCLUSION In this study, the possibility of glioma was considered to be low for cases in which no expansion on MRI was seen after 5 years or more.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1093/noajnl/vdad141.048
- https://academic.oup.com/noa/article-pdf/5/Supplement_5/v12/54205122/vdad141.048.pdf
- OA Status
- gold
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4389515877
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4389515877Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1093/noajnl/vdad141.048Digital Object Identifier
- Title
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10109-COT-13 LONG-TERM FOLLOW-UP OF FLAIR HIGH LESION IN THE BRAINWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2023Year of publication
- Publication date
-
2023-12-01Full publication date if available
- Authors
-
Shohei Fujita, Makoto Ohno, Masamichi Takahashi, Shunsuke Yanagisawa, Sho Osawa, Takahiro Tsuchiya, Yoshitaka NaritaList of authors in order
- Landing page
-
https://doi.org/10.1093/noajnl/vdad141.048Publisher landing page
- PDF URL
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https://academic.oup.com/noa/article-pdf/5/Supplement_5/v12/54205122/vdad141.048.pdfDirect link to full text PDF
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YesWhether a free full text is available
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goldOpen access status per OpenAlex
- OA URL
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https://academic.oup.com/noa/article-pdf/5/Supplement_5/v12/54205122/vdad141.048.pdfDirect OA link when available
- Concepts
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Fluid-attenuated inversion recovery, Medicine, Lesion, Asymptomatic, Biopsy, Neurosurgery, Glioma, Radiology, Brain biopsy, Magnetic resonance imaging, Stereotactic biopsy, Surgery, Cancer researchTop concepts (fields/topics) attached by OpenAlex
- Cited by
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0Total citation count in OpenAlex
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10Other works algorithmically related by OpenAlex
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