(103) Prior Intracavernosal Injection Therapy and Prostate Cancer Treatment are Both Independently Associated with Increased Risks of Complications in Men Undergoing Inflatable Penile Prosthesis Placement Article Swipe
YOU?
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· 2024
· Open Access
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· DOI: https://doi.org/10.1093/jsxmed/qdae002.094
Introduction Intracavernosal injection (ICI) therapy for erectile dysfunction (ED) carries a risk of corporal fibrosis, potentially making placement of an inflatable penile prosthesis more difficult. Prostate cancer treatment may also induce corporal fibrosis. Objective To assess whether a history of ICI or prostate cancer treatment is associated with complications following IPP placement. Methods A retrospective cohort study of primary IPP cases from 2016–2021 across 16 institutions. Patients were stratified by history of ICI and between-group differences in risk factors were assessed. Multivariable logistic regression was used to assess for predictors of intraoperative complications, postoperative non-infectious complications and postoperative infection. Results A total of 2540 patients met inclusion criteria of which 781 (30.8%) had a history of ICI. Patients with a history of ICI tended to be older (mean 63 vs 64 years, p=0.002) and were more likely to have history of radical prostatectomy (21.0% vs. 32.1%, p<0.001) and/or radiation (5.51% vs 10.9%, p<0.001). On multivariable regression, a history of ICI, prostatectomy, and radiation were all significant predictors of intraoperative complications (OR 2.11, p=0.03; OR 2.27, p=0.03; OR 2.40, p=0.04, respectively). A history of ICI and patient age were predictors of non-infectious postoperative complications (OR 1.44, p=0.02, OR 1.02, p=0.004 respectively)). None of the variables were significant predictors of infection. Conclusions In men undergoing IPP placement, a history of ICI is associated with an increased risk of both intraoperative and postoperative, non-infectious complications. Prostate cancer treatment with radiation or surgery is independently associated with increased risk of intraoperative complications. Disclosure Any of the authors act as a consultant, employee or shareholder of an industry for: D.O. has served as a consultant for Coloplast, Intuitive Surgical, and Fidelis. P.P. has served as a consultant for Coloplast, Boston Scientific, and Urofill. M.S. has served as a consultant for Boston Scientific and Coloplast. J.S. has served as a consultant for Boston Scientific and Coloplast. F.A.Y. has served as a consultant for Coloplast, Cynosure, Antares Pharma, Clarus Pharmaceuticals, and Acerus Pharma. M.S.G. has served as a consultant for Coloplast. The other authors disclose no conflicts.
Related Topics
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1093/jsxmed/qdae002.094
- https://academic.oup.com/jsm/article-pdf/21/Supplement_2/qdae002.094/56824397/qdae002.094.pdf
- OA Status
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- Related Works
- 10
- OpenAlex ID
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Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4392471025Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1093/jsxmed/qdae002.094Digital Object Identifier
- Title
-
(103) Prior Intracavernosal Injection Therapy and Prostate Cancer Treatment are Both Independently Associated with Increased Risks of Complications in Men Undergoing Inflatable Penile Prosthesis PlacementWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2024Year of publication
- Publication date
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2024-03-01Full publication date if available
- Authors
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Muhammed Hammad, David W. Barham, Julie Jones, Martin Gross, Chun‐Chao Chang, Daniel Swerdloff, Justin Miller, Robert Andrianne, Arthur L. Burnett, Kelli Gross, G Hatzichristodoulou, James M. Hotaling, T.‐C. Hsieh, Adam Jones, Aaron Lentz, Vaibhav Modgil, Daniar Osmonov, S H Park, Ian Pearce, Paul Perito, Hossein Sadeghi‐Nejad, Maxime Sempels, Alfredo Suarez‐Sarmiento, J Simhan, Koenraad van Renterghem, J Warner, Matthew Ziegelmann, Faysal A. YafiList of authors in order
- Landing page
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https://doi.org/10.1093/jsxmed/qdae002.094Publisher landing page
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https://academic.oup.com/jsm/article-pdf/21/Supplement_2/qdae002.094/56824397/qdae002.094.pdfDirect link to full text PDF
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bronzeOpen access status per OpenAlex
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https://academic.oup.com/jsm/article-pdf/21/Supplement_2/qdae002.094/56824397/qdae002.094.pdfDirect OA link when available
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Medicine, Prostate cancer, Erectile dysfunction, Prostatectomy, Retrospective cohort study, Penile prosthesis, Logistic regression, Surgery, Cohort, Urology, Cancer, Internal medicineTop concepts (fields/topics) attached by OpenAlex
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0Total citation count in OpenAlex
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10Other works algorithmically related by OpenAlex
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| publication_date | 2024-03-01 |
| publication_year | 2024 |
| referenced_works_count | 0 |
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