#146 : Low-Lactate Culture Medium Increases the Percentage of Usable Blastocysts from Advanced Maternal Age Patients: A Sibling-Oocyte, Monocentric Study Article Swipe
Hiromitsu Hattori
,
Mizuho Takahashi
,
Mayumi Toya
,
Hideki Igarashi
,
Koichi Kyono
·
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.1142/s2661318223744053
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.1142/s2661318223744053
Background and Aims: Excess lactate in culture medium accumulates may adversely affect the embryo as metabolic stress. The purpose of this study is to investigate whether culture media with a low-lactate concentration have an effect on embryonic development in IVF. Method: A split sibling study was performed on 8313 oocytes from 1,312 ICSI cycles from which at least two matured oocytes were retrieved from January 2020 through August 2022. Sperm-injected oocytes were allocated to Continuous Single Culture-NX (NX, N=4352) which contains a low concentration of lactate (1mM) and Global Ⓡ total Ⓡ LP (GL, N=3961), which contains 5mM concentration of lactate. Patients were classified into subgroups of <40 years (854 cycles) and [Formula: see text]40 years (458 cycles). Single frozen embryo transfers were performed in 859 cycles (NX; N = 500, GL; N = 359). Embryo development up to Day 6, clinical pregnancy and miscarriage rates were compared. Usable blastocysts were defined as any blastocyst cryopreserved on day 5 or day 6. P<0.05 was considered statistically significant. Results: The mean patient age was 37.1 ± 4.4 years. Overall fertilization rates and the blastocyst development rate were significantly higher in NX than GL (80.7% vs. 78.9% and 62.3% vs. 59.8% respectively). There was no significant difference in blastocyst utilization rate on day 5 with all ages considered (36.2% NX vs. 34.2% GL). There was no significant difference in blastocyst development rate for patients [Formula: see text]40 years, but for patients [Formula: see text]40 years, blastocyst development rate and day 5 usable blastocyst rate were significantly increased in NX (51.2% vs. 46.4% and 26.2% vs. 22.4% respectively). There were no significant differences in the clinical pregnancy or miscarriage rates (48.8% vs. 49.9% and 22.1% vs. 21.8% respectively). Conclusion: Our results suggest that the lower concentration of lactate in culture medium is effective for late embryonic development in advanced maternal age patients.
Related Topics
Concepts
Metadata
- Type
- article
- Language
- en
- Landing Page
- http://doi.org/10.1142/s2661318223744053
- OA Status
- diamond
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4391357970
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4391357970Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1142/s2661318223744053Digital Object Identifier
- Title
-
#146 : Low-Lactate Culture Medium Increases the Percentage of Usable Blastocysts from Advanced Maternal Age Patients: A Sibling-Oocyte, Monocentric StudyWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2023Year of publication
- Publication date
-
2023-12-01Full publication date if available
- Authors
-
Hiromitsu Hattori, Mizuho Takahashi, Mayumi Toya, Hideki Igarashi, Koichi KyonoList of authors in order
- Landing page
-
https://doi.org/10.1142/s2661318223744053Publisher landing page
- Open access
-
YesWhether a free full text is available
- OA status
-
diamondOpen access status per OpenAlex
- OA URL
-
https://doi.org/10.1142/s2661318223744053Direct OA link when available
- Concepts
-
Andrology, Sibling, Oocyte, USable, Biology, Embryo, Medicine, Genetics, Psychology, Developmental psychology, Computer science, World Wide WebTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
0Total citation count in OpenAlex
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W4391357970 |
|---|---|
| doi | https://doi.org/10.1142/s2661318223744053 |
| ids.doi | https://doi.org/10.1142/s2661318223744053 |
| ids.openalex | https://openalex.org/W4391357970 |
| fwci | 0.0 |
| type | article |
| title | #146 : Low-Lactate Culture Medium Increases the Percentage of Usable Blastocysts from Advanced Maternal Age Patients: A Sibling-Oocyte, Monocentric Study |
| biblio.issue | 04 |
| biblio.volume | 05 |
| biblio.last_page | 690 |
| biblio.first_page | 690 |
| topics[0].id | https://openalex.org/T10364 |
| topics[0].field.id | https://openalex.org/fields/27 |
| topics[0].field.display_name | Medicine |
| topics[0].score | 0.9943000078201294 |
| topics[0].domain.id | https://openalex.org/domains/4 |
| topics[0].domain.display_name | Health Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/2739 |
| topics[0].subfield.display_name | Public Health, Environmental and Occupational Health |
| topics[0].display_name | Reproductive Biology and Fertility |
| is_xpac | False |
| apc_list | |
| apc_paid | |
| concepts[0].id | https://openalex.org/C16685009 |
| concepts[0].level | 1 |
| concepts[0].score | 0.6274658441543579 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q335057 |
| concepts[0].display_name | Andrology |
| concepts[1].id | https://openalex.org/C2776194465 |
| concepts[1].level | 2 |
| concepts[1].score | 0.6234200596809387 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q31184 |
| concepts[1].display_name | Sibling |
| concepts[2].id | https://openalex.org/C2776690073 |
| concepts[2].level | 3 |
| concepts[2].score | 0.48622217774391174 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q3246226 |
| concepts[2].display_name | Oocyte |
| concepts[3].id | https://openalex.org/C2780615836 |
| concepts[3].level | 2 |
| concepts[3].score | 0.4399348497390747 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q2471869 |
| concepts[3].display_name | USable |
| concepts[4].id | https://openalex.org/C86803240 |
| concepts[4].level | 0 |
| concepts[4].score | 0.37581899762153625 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q420 |
| concepts[4].display_name | Biology |
| concepts[5].id | https://openalex.org/C196843134 |
| concepts[5].level | 2 |
| concepts[5].score | 0.3069910705089569 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q33196 |
| concepts[5].display_name | Embryo |
| concepts[6].id | https://openalex.org/C71924100 |
| concepts[6].level | 0 |
| concepts[6].score | 0.2934282422065735 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q11190 |
| concepts[6].display_name | Medicine |
| concepts[7].id | https://openalex.org/C54355233 |
| concepts[7].level | 1 |
| concepts[7].score | 0.14351269602775574 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q7162 |
| concepts[7].display_name | Genetics |
| concepts[8].id | https://openalex.org/C15744967 |
| concepts[8].level | 0 |
| concepts[8].score | 0.1162475049495697 |
| concepts[8].wikidata | https://www.wikidata.org/wiki/Q9418 |
| concepts[8].display_name | Psychology |
| concepts[9].id | https://openalex.org/C138496976 |
| concepts[9].level | 1 |
| concepts[9].score | 0.07885736227035522 |
| concepts[9].wikidata | https://www.wikidata.org/wiki/Q175002 |
| concepts[9].display_name | Developmental psychology |
| concepts[10].id | https://openalex.org/C41008148 |
| concepts[10].level | 0 |
| concepts[10].score | 0.06921118497848511 |
| concepts[10].wikidata | https://www.wikidata.org/wiki/Q21198 |
| concepts[10].display_name | Computer science |
| concepts[11].id | https://openalex.org/C136764020 |
| concepts[11].level | 1 |
| concepts[11].score | 0.0 |
| concepts[11].wikidata | https://www.wikidata.org/wiki/Q466 |
| concepts[11].display_name | World Wide Web |
| keywords[0].id | https://openalex.org/keywords/andrology |
| keywords[0].score | 0.6274658441543579 |
| keywords[0].display_name | Andrology |
| keywords[1].id | https://openalex.org/keywords/sibling |
| keywords[1].score | 0.6234200596809387 |
| keywords[1].display_name | Sibling |
| keywords[2].id | https://openalex.org/keywords/oocyte |
| keywords[2].score | 0.48622217774391174 |
| keywords[2].display_name | Oocyte |
| keywords[3].id | https://openalex.org/keywords/usable |
| keywords[3].score | 0.4399348497390747 |
| keywords[3].display_name | USable |
| keywords[4].id | https://openalex.org/keywords/biology |
| keywords[4].score | 0.37581899762153625 |
| keywords[4].display_name | Biology |
| keywords[5].id | https://openalex.org/keywords/embryo |
| keywords[5].score | 0.3069910705089569 |
| keywords[5].display_name | Embryo |
| keywords[6].id | https://openalex.org/keywords/medicine |
| keywords[6].score | 0.2934282422065735 |
| keywords[6].display_name | Medicine |
| keywords[7].id | https://openalex.org/keywords/genetics |
| keywords[7].score | 0.14351269602775574 |
| keywords[7].display_name | Genetics |
| keywords[8].id | https://openalex.org/keywords/psychology |
| keywords[8].score | 0.1162475049495697 |
| keywords[8].display_name | Psychology |
| keywords[9].id | https://openalex.org/keywords/developmental-psychology |
| keywords[9].score | 0.07885736227035522 |
| keywords[9].display_name | Developmental psychology |
| keywords[10].id | https://openalex.org/keywords/computer-science |
| keywords[10].score | 0.06921118497848511 |
| keywords[10].display_name | Computer science |
| language | en |
| locations[0].id | doi:10.1142/s2661318223744053 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S4210193017 |
| locations[0].source.issn | 2661-3174, 2661-3182 |
| locations[0].source.type | journal |
| locations[0].source.is_oa | True |
| locations[0].source.issn_l | 2661-3174 |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | True |
| locations[0].source.display_name | Fertility & Reproduction |
| locations[0].source.host_organization | https://openalex.org/P4310319815 |
| locations[0].source.host_organization_name | World Scientific |
| locations[0].source.host_organization_lineage | https://openalex.org/P4310319815 |
| locations[0].source.host_organization_lineage_names | World Scientific |
| locations[0].license | cc-by-nc-nd |
| locations[0].pdf_url | |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | https://openalex.org/licenses/cc-by-nc-nd |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | Fertility & Reproduction |
| locations[0].landing_page_url | http://doi.org/10.1142/s2661318223744053 |
| locations[1].id | pmh:oai:doaj.org/article:2c76333647424eb6915ed902029f8f2c |
| locations[1].is_oa | False |
| locations[1].source.id | https://openalex.org/S4306401280 |
| locations[1].source.issn | |
| locations[1].source.type | repository |
| locations[1].source.is_oa | False |
| locations[1].source.issn_l | |
| locations[1].source.is_core | False |
| locations[1].source.is_in_doaj | False |
| locations[1].source.display_name | DOAJ (DOAJ: Directory of Open Access Journals) |
| locations[1].source.host_organization | |
| locations[1].source.host_organization_name | |
| locations[1].license | |
| locations[1].pdf_url | |
| locations[1].version | submittedVersion |
| locations[1].raw_type | article |
| locations[1].license_id | |
| locations[1].is_accepted | False |
| locations[1].is_published | False |
| locations[1].raw_source_name | Fertility & Reproduction, Vol 05, Iss 04, Pp 690-690 (2023) |
| locations[1].landing_page_url | https://doaj.org/article/2c76333647424eb6915ed902029f8f2c |
| indexed_in | crossref, doaj |
| authorships[0].author.id | https://openalex.org/A5119824589 |
| authorships[0].author.orcid | https://orcid.org/0009-0001-0522-7760 |
| authorships[0].author.display_name | Hiromitsu Hattori |
| authorships[0].countries | JP |
| authorships[0].affiliations[0].raw_affiliation_string | Kyono ART Clinic Morioka, Morioka, Japan |
| authorships[0].affiliations[1].institution_ids | https://openalex.org/I181637171 |
| authorships[0].affiliations[1].raw_affiliation_string | Kyono ART Clinic Takanawa, Minatoku, Japan |
| authorships[0].affiliations[2].raw_affiliation_string | HOPE, Minatoku, Japan |
| authorships[0].affiliations[3].institution_ids | https://openalex.org/I181637171 |
| authorships[0].affiliations[3].raw_affiliation_string | Kyono ART Clinic Sendai, Sendai, Japan |
| authorships[0].institutions[0].id | https://openalex.org/I181637171 |
| authorships[0].institutions[0].ror | https://ror.org/04qdzzb42 |
| authorships[0].institutions[0].type | education |
| authorships[0].institutions[0].lineage | https://openalex.org/I181637171 |
| authorships[0].institutions[0].country_code | JP |
| authorships[0].institutions[0].display_name | Musashino Art University |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Hiromitsu Hattori |
| authorships[0].is_corresponding | False |
| authorships[0].raw_affiliation_strings | HOPE, Minatoku, Japan, Kyono ART Clinic Morioka, Morioka, Japan, Kyono ART Clinic Sendai, Sendai, Japan, Kyono ART Clinic Takanawa, Minatoku, Japan |
| authorships[1].author.id | https://openalex.org/A5111976713 |
| authorships[1].author.orcid | |
| authorships[1].author.display_name | Mizuho Takahashi |
| authorships[1].countries | JP |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I181637171 |
| authorships[1].affiliations[0].raw_affiliation_string | Kyono ART Clinic Sendai, Sendai, Japan |
| authorships[1].institutions[0].id | https://openalex.org/I181637171 |
| authorships[1].institutions[0].ror | https://ror.org/04qdzzb42 |
| authorships[1].institutions[0].type | education |
| authorships[1].institutions[0].lineage | https://openalex.org/I181637171 |
| authorships[1].institutions[0].country_code | JP |
| authorships[1].institutions[0].display_name | Musashino Art University |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Mizuho Takahashi |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | Kyono ART Clinic Sendai, Sendai, Japan |
| authorships[2].author.id | https://openalex.org/A5105302540 |
| authorships[2].author.orcid | |
| authorships[2].author.display_name | Mayumi Toya |
| authorships[2].countries | JP |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I181637171 |
| authorships[2].affiliations[0].raw_affiliation_string | Kyono ART Clinic Sendai, Sendai, Japan |
| authorships[2].institutions[0].id | https://openalex.org/I181637171 |
| authorships[2].institutions[0].ror | https://ror.org/04qdzzb42 |
| authorships[2].institutions[0].type | education |
| authorships[2].institutions[0].lineage | https://openalex.org/I181637171 |
| authorships[2].institutions[0].country_code | JP |
| authorships[2].institutions[0].display_name | Musashino Art University |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Mayumi Toya |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | Kyono ART Clinic Sendai, Sendai, Japan |
| authorships[3].author.id | https://openalex.org/A5056415319 |
| authorships[3].author.orcid | https://orcid.org/0000-0002-3478-497X |
| authorships[3].author.display_name | Hideki Igarashi |
| authorships[3].countries | JP |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I181637171 |
| authorships[3].affiliations[0].raw_affiliation_string | Kyono ART Clinic Sendai, Sendai, Japan |
| authorships[3].institutions[0].id | https://openalex.org/I181637171 |
| authorships[3].institutions[0].ror | https://ror.org/04qdzzb42 |
| authorships[3].institutions[0].type | education |
| authorships[3].institutions[0].lineage | https://openalex.org/I181637171 |
| authorships[3].institutions[0].country_code | JP |
| authorships[3].institutions[0].display_name | Musashino Art University |
| authorships[3].author_position | middle |
| authorships[3].raw_author_name | Hideki Igarashi |
| authorships[3].is_corresponding | False |
| authorships[3].raw_affiliation_strings | Kyono ART Clinic Sendai, Sendai, Japan |
| authorships[4].author.id | https://openalex.org/A5010918405 |
| authorships[4].author.orcid | https://orcid.org/0000-0001-5211-7778 |
| authorships[4].author.display_name | Koichi Kyono |
| authorships[4].countries | JP |
| authorships[4].affiliations[0].institution_ids | https://openalex.org/I181637171 |
| authorships[4].affiliations[0].raw_affiliation_string | Kyono ART Clinic Sendai, Sendai, Japan |
| authorships[4].affiliations[1].raw_affiliation_string | Kyono ART Clinic Morioka, Morioka, Japan |
| authorships[4].affiliations[2].raw_affiliation_string | HOPE, Minatoku, Japan |
| authorships[4].affiliations[3].institution_ids | https://openalex.org/I181637171 |
| authorships[4].affiliations[3].raw_affiliation_string | Kyono ART Clinic Takanawa, Minatoku, Japan |
| authorships[4].institutions[0].id | https://openalex.org/I181637171 |
| authorships[4].institutions[0].ror | https://ror.org/04qdzzb42 |
| authorships[4].institutions[0].type | education |
| authorships[4].institutions[0].lineage | https://openalex.org/I181637171 |
| authorships[4].institutions[0].country_code | JP |
| authorships[4].institutions[0].display_name | Musashino Art University |
| authorships[4].author_position | last |
| authorships[4].raw_author_name | Koichi Kyono |
| authorships[4].is_corresponding | False |
| authorships[4].raw_affiliation_strings | HOPE, Minatoku, Japan, Kyono ART Clinic Morioka, Morioka, Japan, Kyono ART Clinic Sendai, Sendai, Japan, Kyono ART Clinic Takanawa, Minatoku, Japan |
| has_content.pdf | False |
| has_content.grobid_xml | False |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | http://doi.org/10.1142/s2661318223744053 |
| open_access.oa_status | diamond |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | #146 : Low-Lactate Culture Medium Increases the Percentage of Usable Blastocysts from Advanced Maternal Age Patients: A Sibling-Oocyte, Monocentric Study |
| has_fulltext | False |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T10364 |
| primary_topic.field.id | https://openalex.org/fields/27 |
| primary_topic.field.display_name | Medicine |
| primary_topic.score | 0.9943000078201294 |
| primary_topic.domain.id | https://openalex.org/domains/4 |
| primary_topic.domain.display_name | Health Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/2739 |
| primary_topic.subfield.display_name | Public Health, Environmental and Occupational Health |
| primary_topic.display_name | Reproductive Biology and Fertility |
| related_works | https://openalex.org/W2410545972, https://openalex.org/W4241836910, https://openalex.org/W2944695536, https://openalex.org/W2367320353, https://openalex.org/W2082266812, https://openalex.org/W2328759360, https://openalex.org/W1997305124, https://openalex.org/W2971755608, https://openalex.org/W2060387861, https://openalex.org/W2330071096 |
| cited_by_count | 0 |
| locations_count | 2 |
| best_oa_location.id | doi:10.1142/s2661318223744053 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S4210193017 |
| best_oa_location.source.issn | 2661-3174, 2661-3182 |
| best_oa_location.source.type | journal |
| best_oa_location.source.is_oa | True |
| best_oa_location.source.issn_l | 2661-3174 |
| best_oa_location.source.is_core | True |
| best_oa_location.source.is_in_doaj | True |
| best_oa_location.source.display_name | Fertility & Reproduction |
| best_oa_location.source.host_organization | https://openalex.org/P4310319815 |
| best_oa_location.source.host_organization_name | World Scientific |
| best_oa_location.source.host_organization_lineage | https://openalex.org/P4310319815 |
| best_oa_location.source.host_organization_lineage_names | World Scientific |
| best_oa_location.license | cc-by-nc-nd |
| best_oa_location.pdf_url | |
| best_oa_location.version | publishedVersion |
| best_oa_location.raw_type | journal-article |
| best_oa_location.license_id | https://openalex.org/licenses/cc-by-nc-nd |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | True |
| best_oa_location.raw_source_name | Fertility & Reproduction |
| best_oa_location.landing_page_url | http://doi.org/10.1142/s2661318223744053 |
| primary_location.id | doi:10.1142/s2661318223744053 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S4210193017 |
| primary_location.source.issn | 2661-3174, 2661-3182 |
| primary_location.source.type | journal |
| primary_location.source.is_oa | True |
| primary_location.source.issn_l | 2661-3174 |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | True |
| primary_location.source.display_name | Fertility & Reproduction |
| primary_location.source.host_organization | https://openalex.org/P4310319815 |
| primary_location.source.host_organization_name | World Scientific |
| primary_location.source.host_organization_lineage | https://openalex.org/P4310319815 |
| primary_location.source.host_organization_lineage_names | World Scientific |
| primary_location.license | cc-by-nc-nd |
| primary_location.pdf_url | |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | https://openalex.org/licenses/cc-by-nc-nd |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | Fertility & Reproduction |
| primary_location.landing_page_url | http://doi.org/10.1142/s2661318223744053 |
| publication_date | 2023-12-01 |
| publication_year | 2023 |
| referenced_works_count | 0 |
| abstract_inverted_index.5 | 158, 211, 248 |
| abstract_inverted_index.= | 129, 133 |
| abstract_inverted_index.A | 41 |
| abstract_inverted_index.N | 128, 132 |
| abstract_inverted_index.a | 29, 81 |
| abstract_inverted_index.6, | 140 |
| abstract_inverted_index.6. | 161 |
| abstract_inverted_index.GL | 191 |
| abstract_inverted_index.LP | 92 |
| abstract_inverted_index.NX | 189, 217, 256 |
| abstract_inverted_index.an | 33 |
| abstract_inverted_index.as | 14, 152 |
| abstract_inverted_index.at | 56 |
| abstract_inverted_index.in | 5, 38, 124, 188, 205, 226, 255, 270, 295, 304 |
| abstract_inverted_index.is | 22, 298 |
| abstract_inverted_index.no | 202, 223, 267 |
| abstract_inverted_index.of | 19, 84, 99, 106, 293 |
| abstract_inverted_index.on | 35, 47, 156, 209 |
| abstract_inverted_index.or | 159, 274 |
| abstract_inverted_index.to | 23, 73, 138 |
| abstract_inverted_index.up | 137 |
| abstract_inverted_index.± | 174 |
| abstract_inverted_index.4.4 | 175 |
| abstract_inverted_index.5mM | 97 |
| abstract_inverted_index.859 | 125 |
| abstract_inverted_index.Day | 139 |
| abstract_inverted_index.GL; | 131 |
| abstract_inverted_index.Our | 286 |
| abstract_inverted_index.The | 17, 168 |
| abstract_inverted_index.age | 171, 307 |
| abstract_inverted_index.all | 213 |
| abstract_inverted_index.and | 1, 87, 111, 143, 180, 195, 246, 260, 280 |
| abstract_inverted_index.any | 153 |
| abstract_inverted_index.but | 236 |
| abstract_inverted_index.day | 157, 160, 210, 247 |
| abstract_inverted_index.for | 230, 237, 300 |
| abstract_inverted_index.low | 82 |
| abstract_inverted_index.may | 9 |
| abstract_inverted_index.see | 113, 233, 240 |
| abstract_inverted_index.the | 12, 181, 271, 290 |
| abstract_inverted_index.two | 58 |
| abstract_inverted_index.vs. | 193, 197, 218, 258, 262, 278, 282 |
| abstract_inverted_index.was | 45, 163, 172, 201, 222 |
| abstract_inverted_index.Ⓡ | 89, 91 |
| abstract_inverted_index.(458 | 116 |
| abstract_inverted_index.(854 | 109 |
| abstract_inverted_index.(GL, | 93 |
| abstract_inverted_index.(NX, | 77 |
| abstract_inverted_index.(NX; | 127 |
| abstract_inverted_index.2020 | 65 |
| abstract_inverted_index.37.1 | 173 |
| abstract_inverted_index.500, | 130 |
| abstract_inverted_index.8313 | 48 |
| abstract_inverted_index.GL). | 220 |
| abstract_inverted_index.ICSI | 52 |
| abstract_inverted_index.IVF. | 39 |
| abstract_inverted_index.ages | 214 |
| abstract_inverted_index.from | 50, 54, 63 |
| abstract_inverted_index.have | 32 |
| abstract_inverted_index.into | 104 |
| abstract_inverted_index.late | 301 |
| abstract_inverted_index.mean | 169 |
| abstract_inverted_index.rate | 184, 208, 229, 245, 251 |
| abstract_inverted_index.than | 190 |
| abstract_inverted_index.that | 289 |
| abstract_inverted_index.this | 20 |
| abstract_inverted_index.were | 61, 71, 102, 122, 146, 150, 185, 252, 266 |
| abstract_inverted_index.with | 28, 212 |
| abstract_inverted_index.(1mM) | 86 |
| abstract_inverted_index.1,312 | 51 |
| abstract_inverted_index.2022. | 68 |
| abstract_inverted_index.21.8% | 283 |
| abstract_inverted_index.22.1% | 281 |
| abstract_inverted_index.22.4% | 263 |
| abstract_inverted_index.26.2% | 261 |
| abstract_inverted_index.34.2% | 219 |
| abstract_inverted_index.359). | 134 |
| abstract_inverted_index.46.4% | 259 |
| abstract_inverted_index.49.9% | 279 |
| abstract_inverted_index.59.8% | 198 |
| abstract_inverted_index.62.3% | 196 |
| abstract_inverted_index.78.9% | 194 |
| abstract_inverted_index.Aims: | 2 |
| abstract_inverted_index.There | 200, 221, 265 |
| abstract_inverted_index.least | 57 |
| abstract_inverted_index.lower | 291 |
| abstract_inverted_index.media | 27 |
| abstract_inverted_index.rates | 145, 179, 276 |
| abstract_inverted_index.split | 42 |
| abstract_inverted_index.study | 21, 44 |
| abstract_inverted_index.total | 90 |
| abstract_inverted_index.which | 55, 79, 95 |
| abstract_inverted_index.years | 108, 115 |
| abstract_inverted_index.<40 | 107 |
| abstract_inverted_index.(36.2% | 216 |
| abstract_inverted_index.(48.8% | 277 |
| abstract_inverted_index.(51.2% | 257 |
| abstract_inverted_index.(80.7% | 192 |
| abstract_inverted_index.August | 67 |
| abstract_inverted_index.Embryo | 135 |
| abstract_inverted_index.Excess | 3 |
| abstract_inverted_index.Global | 88 |
| abstract_inverted_index.Single | 75, 118 |
| abstract_inverted_index.Usable | 148 |
| abstract_inverted_index.affect | 11 |
| abstract_inverted_index.cycles | 53, 126 |
| abstract_inverted_index.effect | 34 |
| abstract_inverted_index.embryo | 13, 120 |
| abstract_inverted_index.frozen | 119 |
| abstract_inverted_index.higher | 187 |
| abstract_inverted_index.medium | 7, 297 |
| abstract_inverted_index.usable | 249 |
| abstract_inverted_index.years, | 235, 242 |
| abstract_inverted_index.years. | 176 |
| abstract_inverted_index.January | 64 |
| abstract_inverted_index.Method: | 40 |
| abstract_inverted_index.N=4352) | 78 |
| abstract_inverted_index.Overall | 177 |
| abstract_inverted_index.culture | 6, 26, 296 |
| abstract_inverted_index.cycles) | 110 |
| abstract_inverted_index.defined | 151 |
| abstract_inverted_index.lactate | 4, 85, 294 |
| abstract_inverted_index.matured | 59 |
| abstract_inverted_index.oocytes | 49, 60, 70 |
| abstract_inverted_index.patient | 170 |
| abstract_inverted_index.purpose | 18 |
| abstract_inverted_index.results | 287 |
| abstract_inverted_index.sibling | 43 |
| abstract_inverted_index.stress. | 16 |
| abstract_inverted_index.suggest | 288 |
| abstract_inverted_index.text]40 | 114, 234, 241 |
| abstract_inverted_index.through | 66 |
| abstract_inverted_index.whether | 25 |
| abstract_inverted_index.N=3961), | 94 |
| abstract_inverted_index.Patients | 101 |
| abstract_inverted_index.Results: | 167 |
| abstract_inverted_index.advanced | 305 |
| abstract_inverted_index.clinical | 141, 272 |
| abstract_inverted_index.contains | 80, 96 |
| abstract_inverted_index.cycles). | 117 |
| abstract_inverted_index.lactate. | 100 |
| abstract_inverted_index.maternal | 306 |
| abstract_inverted_index.patients | 231, 238 |
| abstract_inverted_index.P<0.05 | 162 |
| abstract_inverted_index.[Formula: | 112, 232, 239 |
| abstract_inverted_index.adversely | 10 |
| abstract_inverted_index.allocated | 72 |
| abstract_inverted_index.compared. | 147 |
| abstract_inverted_index.effective | 299 |
| abstract_inverted_index.embryonic | 36, 302 |
| abstract_inverted_index.increased | 254 |
| abstract_inverted_index.metabolic | 15 |
| abstract_inverted_index.patients. | 308 |
| abstract_inverted_index.performed | 46, 123 |
| abstract_inverted_index.pregnancy | 142, 273 |
| abstract_inverted_index.retrieved | 62 |
| abstract_inverted_index.subgroups | 105 |
| abstract_inverted_index.transfers | 121 |
| abstract_inverted_index.Background | 0 |
| abstract_inverted_index.Continuous | 74 |
| abstract_inverted_index.Culture-NX | 76 |
| abstract_inverted_index.blastocyst | 154, 182, 206, 227, 243, 250 |
| abstract_inverted_index.classified | 103 |
| abstract_inverted_index.considered | 164, 215 |
| abstract_inverted_index.difference | 204, 225 |
| abstract_inverted_index.Conclusion: | 285 |
| abstract_inverted_index.accumulates | 8 |
| abstract_inverted_index.blastocysts | 149 |
| abstract_inverted_index.development | 37, 136, 183, 228, 244, 303 |
| abstract_inverted_index.differences | 269 |
| abstract_inverted_index.investigate | 24 |
| abstract_inverted_index.low-lactate | 30 |
| abstract_inverted_index.miscarriage | 144, 275 |
| abstract_inverted_index.significant | 203, 224, 268 |
| abstract_inverted_index.utilization | 207 |
| abstract_inverted_index.significant. | 166 |
| abstract_inverted_index.concentration | 31, 83, 98, 292 |
| abstract_inverted_index.cryopreserved | 155 |
| abstract_inverted_index.fertilization | 178 |
| abstract_inverted_index.significantly | 186, 253 |
| abstract_inverted_index.statistically | 165 |
| abstract_inverted_index.Sperm-injected | 69 |
| abstract_inverted_index.respectively). | 199, 264, 284 |
| cited_by_percentile_year | |
| countries_distinct_count | 1 |
| institutions_distinct_count | 5 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/3 |
| sustainable_development_goals[0].score | 0.44999998807907104 |
| sustainable_development_goals[0].display_name | Good health and well-being |
| citation_normalized_percentile.value | 0.36104317 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |