31. Left ventricular dysfunction after patent ductus arteriosus (PDA) closure Article Swipe

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Rihab Agouba , Rihab Agouba , Mohammed H. Alghamdi , Fahad Alhabshan ·

YOU? · · 2015 · Open Access · · DOI: https://doi.org/10.1016/j.jsha.2015.05.212

Left ventricular (LV) dysfunction is a known complication after patent ductus arteriosus (PDA) occlusion. However, only limited studies with small number of patients and shorter duration of follow up were published. The study objective is to evaluate the effect of PDA occlusion on LV systolic function (LV-SFx). Methods: A retrospective study conducted from January 2003 till December 2013. Our cardiac database was used to identify all patients who underwent either surgical or catheter occlusion for PDA in this study period. Our echocardiography (echo) data base was used for echo review. From M-Mode recordings, LV dimensions were measured and Fractional Shortening (FS) derived before and after the intervention to assess LV-Sfx. The end-point of follow-up was either a normalization of LV-SFx defined by FS equal to/or more than 28% or reaching one year of follow-up after the intervention in patients with depressed LV-SFx. Patients with depressed LV-SFx prior to PDA occlusion, additional hemodynamically significant cardiac defects, multiple PDA interventions, incomplete follow-up or incomplete echo studies were excluded. Results: The total number of patients who underwent one intervention for PDA occlusion and had complete echo data were 188. 16/188 patients (8.5%) were born prematurely. 159 patients (85%) had normal LV-SFx while 29 patients (15%) had depressed LV-SFx after PDA occlusion. Of those with depressed function, 7 patients were after surgical PDA ligation while 22 patients had catheter PDA device occlusion. LV-SFx recovered within 4–6 weeks in 11 patients, within 3–6 months in 11 patients, and within 7–12 months in 7 patients. Within the first 6 month, complete recovery of LV-SFx was observed in 70% of these patients. None of the preterm babies in our study had depressed LV-SFx after PDA occlusion. Conclusions: Depressed LV-SFx may occur after PDA closure with higher incidence after catheter PDA device occlusion. All of preterm babies had surgical PDA occlusion and none of them presented with depressed LV-SFx in the post-operative follow-up. Further prospective studies are needed to investigate these observations.

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Medicine Ductus arteriosus Closure (psychology) Cardiology Internal medicine Market economy Economics

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Type: article
Language: en
Landing Page: https://doi.org/10.1016/j.jsha.2015.05.212
OA Status: diamond
Cited By: 1
Related Works: 10
OpenAlex ID: https://openalex.org/W1928007977

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DOI: https://doi.org/10.1016/j.jsha.2015.05.212

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Title: 31. Left ventricular dysfunction after patent ductus arteriosus (PDA) closure

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Language: en

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Publication year: 2015

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Publication date: 2015-09-27

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Authors: Rihab Agouba, Rihab Agouba, Mohammed H. Alghamdi, Fahad Alhabshan

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Landing page: https://doi.org/10.1016/j.jsha.2015.05.212

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OA URL: https://doi.org/10.1016/j.jsha.2015.05.212

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Concepts: Medicine, Ductus arteriosus, Closure (psychology), Cardiology, Internal medicine, Market economy, Economics

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Cited by: 1

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abstract_inverted_index.review.	89
abstract_inverted_index.shorter	24
abstract_inverted_index.studies	17, 163, 317
abstract_inverted_index.December	56
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abstract_inverted_index.Methods:	47
abstract_inverted_index.Patients	142
abstract_inverted_index.Results:	166
abstract_inverted_index.catheter	72, 224, 291
abstract_inverted_index.complete	181, 254
abstract_inverted_index.database	60
abstract_inverted_index.defects,	154
abstract_inverted_index.duration	25
abstract_inverted_index.evaluate	36
abstract_inverted_index.function	45
abstract_inverted_index.identify	64
abstract_inverted_index.ligation	219
abstract_inverted_index.measured	96
abstract_inverted_index.multiple	155
abstract_inverted_index.observed	259
abstract_inverted_index.patients	22, 66, 138, 171, 187, 193, 200, 214, 222
abstract_inverted_index.reaching	129
abstract_inverted_index.recovery	255
abstract_inverted_index.surgical	70, 217, 300
abstract_inverted_index.systolic	44
abstract_inverted_index.(LV-SFx).	46
abstract_inverted_index.Depressed	280
abstract_inverted_index.conducted	51
abstract_inverted_index.depressed	140, 144, 203, 211, 274, 309
abstract_inverted_index.end-point	111
abstract_inverted_index.excluded.	165
abstract_inverted_index.follow-up	113, 133, 159
abstract_inverted_index.function,	212
abstract_inverted_index.incidence	289
abstract_inverted_index.objective	33
abstract_inverted_index.occlusion	41, 73, 178, 302
abstract_inverted_index.patients,	235, 241
abstract_inverted_index.patients.	248, 264
abstract_inverted_index.presented	307
abstract_inverted_index.recovered	229
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abstract_inverted_index.Shortening	99
abstract_inverted_index.additional	150
abstract_inverted_index.arteriosus	11
abstract_inverted_index.dimensions	94
abstract_inverted_index.follow-up.	314
abstract_inverted_index.incomplete	158, 161
abstract_inverted_index.occlusion,	149
abstract_inverted_index.occlusion.	13, 207, 227, 278, 294
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abstract_inverted_index.dysfunction	3
abstract_inverted_index.investigate	321
abstract_inverted_index.prospective	316
abstract_inverted_index.recordings,	92
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abstract_inverted_index.intervention	106, 136, 175
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cited_by_percentile_year.min	89
countries_distinct_count	1
institutions_distinct_count	4
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