3D Printing for Affinity Chromatographic Support Production Article Swipe
Joana F. A. Valente
,
Juliana R. Dias
,
Fani Sousa
,
Nuno Alves
·
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.3390/materproc2022008082
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.3390/materproc2022008082
first_page settings Order Article Reprints Font Type: Arial Georgia Verdana Font Size: Aa Aa Aa Line Spacing: Column Width: Background: Open AccessAbstract 3D Printing for Affinity Chromatographic Support Production † by Joana F. A. Valente 1,*, Juliana R. Dias 1, Fani Sousa 2 and Nuno Alves 1,* 1 CDRSP-IPL—Centre for Rapid and Sustainable Product Development, Polytechnic of Leiria, Leiria, Rua de Portugal, 2430-028 Marinha Grande, Portugal 2 CICS-UBI—Health Science Research Centre, University of Beira Interior, Av. Infante D. Henrique, 6200-506 Covilhã, Portugal * Authors to whom correspondence should be addressed. † Presented at the Materiais 2022, Marinha Grande, Portugal, 10–13 April 2022. Mater. Proc. 2022, 8(1), 82; https://doi.org/10.3390/materproc2022008082 Published: 8 June 2022 (This article belongs to the Proceedings of MATERIAIS 2022) Download Download PDF Download XML Download Epub Versions Notes The development and growth of biopharmaceutical therapies lead to a demand for efficient chromatographic methods to purify desired biomolecules (e.g., nucleic acids, enzymes or monoclonal antibodies) which are presently under consideration or approved by the Food and Drug Administration. These molecules have distinct chemical and size properties which are critical cues for the development and production of chromatographic supports. The most common chromatographic supports are based on micro-particulate materials that have a randomly compacted configuration. Also, in the case of monolithic supports, it is not possible to fully control its internal structure [1,2].Accordingly, this slightly different internal morphology and porous structure presented leads to be difficult to predict their chromatographic behaviour which requires careful testing and validation of the quality of the packed chromatographic supports before use. Moreover, bed consolidation is typically evaluated by empirical characterization methods. For these reasons, column packing is often treated as an inexact science, whilst the limited scope to control morphology and porosity with traditionally made monolithic materials can result in low levels of column-to-column reproducibility and often the need arises to individually prepare and validate each monolithic column [3].Meanwhile, 3D printing technology is starting to be used in this field since it could provide full control of the geometry of the produced pieces. Therefore, on the chromatographic field, this technology allows a more defined and uniform convective flow path than the randomly interconnected pores observed on the conventional chromatographic support [4]. This is an extraordinary improvement since it will allow modulating the flow, the pressure and consequently the path of the molecules within the chromatographic support.Although the aforementioned, 3DP methodologies per si will not lead to high-quality pharmaceutical products being needed the association with affinity ligands, such as amino acids to enable reaching high purity yields of the desired molecules. Beyond the most studied amino acids as chromatographic ligands, arginine has been successfully immobilized on different chromatographic supports (namely agarose bead matrices, macroporous matrices and monoliths) to achieve extra pure gene therapy products [5,6].Regarding all the above mentioned, in this work, it was studied the immobilization of arginine on 3DP chromatographic supports. Author ContributionsConceptualization, F.S. and J.F.A.V.; methodology F.S. and J.F.A.V.; validation, F.S., J.R.D. and J.F.A.V.; formal analysis, F.S., J.R.D. and J.F.A.V.; investigation, J.F.A.V.; resources; writing—original draft preparation, J.F.A.V.; writing—review and editing, J.F.A.V. and F.S.; supervision, N.A. and F.S.; funding acquisition, N.A. All authors have read and agreed to the published version of the manuscript.FundingThis work was supported by the Fundação para a Ciência e a Tecnologia (FCT) and Centro2020 through the following Projects: UIDB/04044/2020, UIDP/04044/2020, UIDB/00709/2020, PAMI-ROTEIRO/0328/2013 (Nº 022158), MATIS (CEN-TRO-01-0145-FEDER-000014).Institutional Review Board StatementNot applicable.Informed Consent StatementNot applicable.Data Availability StatementNot applicable.Conflicts of InterestThe authors declare no conflict of interest.ReferencesValente, J.F.A.; Pereira, P.; Sousa, A.; Queiroz, J.A.; Sousa, F. Effect of plasmid DNA size on chitosan or polyethyleneimine polyplexes formulation. Polymers 2021, 13, 793. [Google Scholar] [CrossRef]Valente, J.F.A.; Sousa, A.; Queiroz, J.A.; Sousa, F. DoE to improve supercoiled p53-pDNA purification by O-phospho-l-tyrosine chromatography. J. Chromatogr. B 2019, 1105, 184–192. [Google Scholar] [CrossRef]Hearn, M.T. Trends in additive manufacturing of chromatographic and membrane materials. Curr. Opin. Chem. Eng. 2017, 18, 90–98. [Google Scholar] [CrossRef]Valente, J.F.A.; Sousa, F.; Alves, N. Additive Manufacturing Tools to Improve the Performance of Chromatographic Approaches. Trends Biotechnol. 2021, 39, 970–973. [Google Scholar] [CrossRef]Valente, J.F.A.; Sousa, A.; Azevedo, G.A.; Queiroz, J.A.; Sousa, F. Purification of supercoiled p53-encoding plasmid using an arginine-modified macroporous support. J. Chromatogr. A 2020, 1618, 460890. [Google Scholar] [CrossRef]Azevedo, G.M.; Valente, J.F.A.; Sousa, A.; Pedro, A.Q.; Pereira, P.; Sousa, F.; Queiroz, J.A. Effect of chromatographic conditions on supercoiled plasmid DNA stability and bioactivity. Appl. Sci. 2019, 9, 5170. [Google Scholar] [CrossRef][Green Version]Publisher's Note: MDPI stays neutral with regard to jurisdictional claims in published maps and institutional affiliations. © 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Share and Cite MDPI and ACS Style Valente, J.F.A.; Dias, J.R.; Sousa, F.; Alves, N. 3D Printing for Affinity Chromatographic Support Production. Mater. Proc. 2022, 8, 82. https://doi.org/10.3390/materproc2022008082 AMA Style Valente JFA, Dias JR, Sousa F, Alves N. 3D Printing for Affinity Chromatographic Support Production. Materials Proceedings. 2022; 8(1):82. https://doi.org/10.3390/materproc2022008082 Chicago/Turabian Style Valente, Joana F. A., Juliana R. Dias, Fani Sousa, and Nuno Alves. 2022. "3D Printing for Affinity Chromatographic Support Production" Materials Proceedings 8, no. 1: 82. https://doi.org/10.3390/materproc2022008082 Find Other Styles Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here. Article Metrics No No Article Access Statistics Multiple requests from the same IP address are counted as one view.
Related Topics
Concepts
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.3390/materproc2022008082
- https://www.mdpi.com/2673-4605/8/1/82/pdf?version=1654686673
- OA Status
- hybrid
- References
- 6
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4282963299
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4282963299Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.3390/materproc2022008082Digital Object Identifier
- Title
-
3D Printing for Affinity Chromatographic Support ProductionWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2022Year of publication
- Publication date
-
2022-06-08Full publication date if available
- Authors
-
Joana F. A. Valente, Juliana R. Dias, Fani Sousa, Nuno AlvesList of authors in order
- Landing page
-
https://doi.org/10.3390/materproc2022008082Publisher landing page
- PDF URL
-
https://www.mdpi.com/2673-4605/8/1/82/pdf?version=1654686673Direct link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
hybridOpen access status per OpenAlex
- OA URL
-
https://www.mdpi.com/2673-4605/8/1/82/pdf?version=1654686673Direct OA link when available
- Concepts
-
Computer science, Chemistry, Biomolecule, Chromatographic separation, On demand, Biopharmaceutical, Chromatography, Library science, Materials science, Nanotechnology, Multimedia, Biology, High-performance liquid chromatography, BiotechnologyTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
0Total citation count in OpenAlex
- References (count)
-
6Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W4282963299 |
|---|---|
| doi | https://doi.org/10.3390/materproc2022008082 |
| ids.doi | https://doi.org/10.3390/materproc2022008082 |
| ids.openalex | https://openalex.org/W4282963299 |
| fwci | 0.0 |
| type | article |
| title | 3D Printing for Affinity Chromatographic Support Production |
| biblio.issue | |
| biblio.volume | |
| biblio.last_page | 82 |
| biblio.first_page | 82 |
| topics[0].id | https://openalex.org/T11190 |
| topics[0].field.id | https://openalex.org/fields/22 |
| topics[0].field.display_name | Engineering |
| topics[0].score | 0.9980999827384949 |
| topics[0].domain.id | https://openalex.org/domains/3 |
| topics[0].domain.display_name | Physical Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/2204 |
| topics[0].subfield.display_name | Biomedical Engineering |
| topics[0].display_name | 3D Printing in Biomedical Research |
| topics[1].id | https://openalex.org/T11663 |
| topics[1].field.id | https://openalex.org/fields/13 |
| topics[1].field.display_name | Biochemistry, Genetics and Molecular Biology |
| topics[1].score | 0.9980999827384949 |
| topics[1].domain.id | https://openalex.org/domains/1 |
| topics[1].domain.display_name | Life Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/1312 |
| topics[1].subfield.display_name | Molecular Biology |
| topics[1].display_name | Viral Infectious Diseases and Gene Expression in Insects |
| topics[2].id | https://openalex.org/T12224 |
| topics[2].field.id | https://openalex.org/fields/22 |
| topics[2].field.display_name | Engineering |
| topics[2].score | 0.9968000054359436 |
| topics[2].domain.id | https://openalex.org/domains/3 |
| topics[2].domain.display_name | Physical Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/2204 |
| topics[2].subfield.display_name | Biomedical Engineering |
| topics[2].display_name | Nanofabrication and Lithography Techniques |
| is_xpac | False |
| apc_list | |
| apc_paid | |
| concepts[0].id | https://openalex.org/C41008148 |
| concepts[0].level | 0 |
| concepts[0].score | 0.44864022731781006 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q21198 |
| concepts[0].display_name | Computer science |
| concepts[1].id | https://openalex.org/C185592680 |
| concepts[1].level | 0 |
| concepts[1].score | 0.4333629012107849 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q2329 |
| concepts[1].display_name | Chemistry |
| concepts[2].id | https://openalex.org/C49853544 |
| concepts[2].level | 2 |
| concepts[2].score | 0.42696499824523926 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q206229 |
| concepts[2].display_name | Biomolecule |
| concepts[3].id | https://openalex.org/C2992520659 |
| concepts[3].level | 3 |
| concepts[3].score | 0.4251842498779297 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q170050 |
| concepts[3].display_name | Chromatographic separation |
| concepts[4].id | https://openalex.org/C2983523559 |
| concepts[4].level | 2 |
| concepts[4].score | 0.422078400850296 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q410657 |
| concepts[4].display_name | On demand |
| concepts[5].id | https://openalex.org/C2781047461 |
| concepts[5].level | 2 |
| concepts[5].score | 0.42186370491981506 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q679692 |
| concepts[5].display_name | Biopharmaceutical |
| concepts[6].id | https://openalex.org/C43617362 |
| concepts[6].level | 1 |
| concepts[6].score | 0.39451301097869873 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q170050 |
| concepts[6].display_name | Chromatography |
| concepts[7].id | https://openalex.org/C161191863 |
| concepts[7].level | 1 |
| concepts[7].score | 0.34346839785575867 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q199655 |
| concepts[7].display_name | Library science |
| concepts[8].id | https://openalex.org/C192562407 |
| concepts[8].level | 0 |
| concepts[8].score | 0.3149743378162384 |
| concepts[8].wikidata | https://www.wikidata.org/wiki/Q228736 |
| concepts[8].display_name | Materials science |
| concepts[9].id | https://openalex.org/C171250308 |
| concepts[9].level | 1 |
| concepts[9].score | 0.25901490449905396 |
| concepts[9].wikidata | https://www.wikidata.org/wiki/Q11468 |
| concepts[9].display_name | Nanotechnology |
| concepts[10].id | https://openalex.org/C49774154 |
| concepts[10].level | 1 |
| concepts[10].score | 0.1991465985774994 |
| concepts[10].wikidata | https://www.wikidata.org/wiki/Q131765 |
| concepts[10].display_name | Multimedia |
| concepts[11].id | https://openalex.org/C86803240 |
| concepts[11].level | 0 |
| concepts[11].score | 0.15772408246994019 |
| concepts[11].wikidata | https://www.wikidata.org/wiki/Q420 |
| concepts[11].display_name | Biology |
| concepts[12].id | https://openalex.org/C179998833 |
| concepts[12].level | 2 |
| concepts[12].score | 0.15543314814567566 |
| concepts[12].wikidata | https://www.wikidata.org/wiki/Q381233 |
| concepts[12].display_name | High-performance liquid chromatography |
| concepts[13].id | https://openalex.org/C150903083 |
| concepts[13].level | 1 |
| concepts[13].score | 0.13322106003761292 |
| concepts[13].wikidata | https://www.wikidata.org/wiki/Q7108 |
| concepts[13].display_name | Biotechnology |
| keywords[0].id | https://openalex.org/keywords/computer-science |
| keywords[0].score | 0.44864022731781006 |
| keywords[0].display_name | Computer science |
| keywords[1].id | https://openalex.org/keywords/chemistry |
| keywords[1].score | 0.4333629012107849 |
| keywords[1].display_name | Chemistry |
| keywords[2].id | https://openalex.org/keywords/biomolecule |
| keywords[2].score | 0.42696499824523926 |
| keywords[2].display_name | Biomolecule |
| keywords[3].id | https://openalex.org/keywords/chromatographic-separation |
| keywords[3].score | 0.4251842498779297 |
| keywords[3].display_name | Chromatographic separation |
| keywords[4].id | https://openalex.org/keywords/on-demand |
| keywords[4].score | 0.422078400850296 |
| keywords[4].display_name | On demand |
| keywords[5].id | https://openalex.org/keywords/biopharmaceutical |
| keywords[5].score | 0.42186370491981506 |
| keywords[5].display_name | Biopharmaceutical |
| keywords[6].id | https://openalex.org/keywords/chromatography |
| keywords[6].score | 0.39451301097869873 |
| keywords[6].display_name | Chromatography |
| keywords[7].id | https://openalex.org/keywords/library-science |
| keywords[7].score | 0.34346839785575867 |
| keywords[7].display_name | Library science |
| keywords[8].id | https://openalex.org/keywords/materials-science |
| keywords[8].score | 0.3149743378162384 |
| keywords[8].display_name | Materials science |
| keywords[9].id | https://openalex.org/keywords/nanotechnology |
| keywords[9].score | 0.25901490449905396 |
| keywords[9].display_name | Nanotechnology |
| keywords[10].id | https://openalex.org/keywords/multimedia |
| keywords[10].score | 0.1991465985774994 |
| keywords[10].display_name | Multimedia |
| keywords[11].id | https://openalex.org/keywords/biology |
| keywords[11].score | 0.15772408246994019 |
| keywords[11].display_name | Biology |
| keywords[12].id | https://openalex.org/keywords/high-performance-liquid-chromatography |
| keywords[12].score | 0.15543314814567566 |
| keywords[12].display_name | High-performance liquid chromatography |
| keywords[13].id | https://openalex.org/keywords/biotechnology |
| keywords[13].score | 0.13322106003761292 |
| keywords[13].display_name | Biotechnology |
| language | en |
| locations[0].id | doi:10.3390/materproc2022008082 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S4363606122 |
| locations[0].source.issn | |
| locations[0].source.type | conference |
| locations[0].source.is_oa | False |
| locations[0].source.issn_l | |
| locations[0].source.is_core | False |
| locations[0].source.is_in_doaj | False |
| locations[0].source.display_name | MATERIAIS 2022 |
| locations[0].source.host_organization | |
| locations[0].source.host_organization_name | |
| locations[0].source.host_organization_lineage | |
| locations[0].license | cc-by |
| locations[0].pdf_url | https://www.mdpi.com/2673-4605/8/1/82/pdf?version=1654686673 |
| locations[0].version | publishedVersion |
| locations[0].raw_type | proceedings-article |
| locations[0].license_id | https://openalex.org/licenses/cc-by |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | MATERIAIS 2022 |
| locations[0].landing_page_url | https://doi.org/10.3390/materproc2022008082 |
| indexed_in | crossref |
| authorships[0].author.id | https://openalex.org/A5052998969 |
| authorships[0].author.orcid | https://orcid.org/0000-0002-2408-9762 |
| authorships[0].author.display_name | Joana F. A. Valente |
| authorships[0].countries | PT |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I169427155 |
| authorships[0].affiliations[0].raw_affiliation_string | CDRSP-IPL—Centre for Rapid and Sustainable Product Development, Polytechnic of Leiria, Leiria, Rua de Portugal, 2430-028 Marinha Grande, Portugal |
| authorships[0].institutions[0].id | https://openalex.org/I169427155 |
| authorships[0].institutions[0].ror | https://ror.org/010dvvh94 |
| authorships[0].institutions[0].type | education |
| authorships[0].institutions[0].lineage | https://openalex.org/I169427155 |
| authorships[0].institutions[0].country_code | PT |
| authorships[0].institutions[0].display_name | Instituto Politécnico de Leiria |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Joana F. A. Valente |
| authorships[0].is_corresponding | True |
| authorships[0].raw_affiliation_strings | CDRSP-IPL—Centre for Rapid and Sustainable Product Development, Polytechnic of Leiria, Leiria, Rua de Portugal, 2430-028 Marinha Grande, Portugal |
| authorships[1].author.id | https://openalex.org/A5066975511 |
| authorships[1].author.orcid | https://orcid.org/0000-0002-7079-1069 |
| authorships[1].author.display_name | Juliana R. Dias |
| authorships[1].countries | PT |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I169427155 |
| authorships[1].affiliations[0].raw_affiliation_string | CDRSP-IPL—Centre for Rapid and Sustainable Product Development, Polytechnic of Leiria, Leiria, Rua de Portugal, 2430-028 Marinha Grande, Portugal |
| authorships[1].institutions[0].id | https://openalex.org/I169427155 |
| authorships[1].institutions[0].ror | https://ror.org/010dvvh94 |
| authorships[1].institutions[0].type | education |
| authorships[1].institutions[0].lineage | https://openalex.org/I169427155 |
| authorships[1].institutions[0].country_code | PT |
| authorships[1].institutions[0].display_name | Instituto Politécnico de Leiria |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Juliana R. Dias |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | CDRSP-IPL—Centre for Rapid and Sustainable Product Development, Polytechnic of Leiria, Leiria, Rua de Portugal, 2430-028 Marinha Grande, Portugal |
| authorships[2].author.id | https://openalex.org/A5050360870 |
| authorships[2].author.orcid | https://orcid.org/0000-0001-9996-2194 |
| authorships[2].author.display_name | Fani Sousa |
| authorships[2].countries | PT |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I161321875 |
| authorships[2].affiliations[0].raw_affiliation_string | CICS-UBI—Health Science Research Centre, University of Beira Interior, Av. Infante D. Henrique, 6200-506 Covilhã, Portugal |
| authorships[2].institutions[0].id | https://openalex.org/I161321875 |
| authorships[2].institutions[0].ror | https://ror.org/03nf36p02 |
| authorships[2].institutions[0].type | education |
| authorships[2].institutions[0].lineage | https://openalex.org/I161321875 |
| authorships[2].institutions[0].country_code | PT |
| authorships[2].institutions[0].display_name | University of Beira Interior |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Fani Sousa |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | CICS-UBI—Health Science Research Centre, University of Beira Interior, Av. Infante D. Henrique, 6200-506 Covilhã, Portugal |
| authorships[3].author.id | https://openalex.org/A5049046331 |
| authorships[3].author.orcid | |
| authorships[3].author.display_name | Nuno Alves |
| authorships[3].countries | PT |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I169427155 |
| authorships[3].affiliations[0].raw_affiliation_string | CDRSP-IPL—Centre for Rapid and Sustainable Product Development, Polytechnic of Leiria, Leiria, Rua de Portugal, 2430-028 Marinha Grande, Portugal |
| authorships[3].institutions[0].id | https://openalex.org/I169427155 |
| authorships[3].institutions[0].ror | https://ror.org/010dvvh94 |
| authorships[3].institutions[0].type | education |
| authorships[3].institutions[0].lineage | https://openalex.org/I169427155 |
| authorships[3].institutions[0].country_code | PT |
| authorships[3].institutions[0].display_name | Instituto Politécnico de Leiria |
| authorships[3].author_position | last |
| authorships[3].raw_author_name | Nuno Alves |
| authorships[3].is_corresponding | True |
| authorships[3].raw_affiliation_strings | CDRSP-IPL—Centre for Rapid and Sustainable Product Development, Polytechnic of Leiria, Leiria, Rua de Portugal, 2430-028 Marinha Grande, Portugal |
| has_content.pdf | True |
| has_content.grobid_xml | True |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://www.mdpi.com/2673-4605/8/1/82/pdf?version=1654686673 |
| open_access.oa_status | hybrid |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | 3D Printing for Affinity Chromatographic Support Production |
| has_fulltext | False |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T11190 |
| primary_topic.field.id | https://openalex.org/fields/22 |
| primary_topic.field.display_name | Engineering |
| primary_topic.score | 0.9980999827384949 |
| primary_topic.domain.id | https://openalex.org/domains/3 |
| primary_topic.domain.display_name | Physical Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/2204 |
| primary_topic.subfield.display_name | Biomedical Engineering |
| primary_topic.display_name | 3D Printing in Biomedical Research |
| related_works | https://openalex.org/W2899084033, https://openalex.org/W2748952813, https://openalex.org/W4378695703, https://openalex.org/W2039848115, https://openalex.org/W2353755664, https://openalex.org/W1860066797, https://openalex.org/W2037695253, https://openalex.org/W2072440555, https://openalex.org/W4256465197, https://openalex.org/W1969879548 |
| cited_by_count | 0 |
| locations_count | 1 |
| best_oa_location.id | doi:10.3390/materproc2022008082 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S4363606122 |
| best_oa_location.source.issn | |
| best_oa_location.source.type | conference |
| best_oa_location.source.is_oa | False |
| best_oa_location.source.issn_l | |
| best_oa_location.source.is_core | False |
| best_oa_location.source.is_in_doaj | False |
| best_oa_location.source.display_name | MATERIAIS 2022 |
| best_oa_location.source.host_organization | |
| best_oa_location.source.host_organization_name | |
| best_oa_location.source.host_organization_lineage | |
| best_oa_location.license | cc-by |
| best_oa_location.pdf_url | https://www.mdpi.com/2673-4605/8/1/82/pdf?version=1654686673 |
| best_oa_location.version | publishedVersion |
| best_oa_location.raw_type | proceedings-article |
| best_oa_location.license_id | https://openalex.org/licenses/cc-by |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | True |
| best_oa_location.raw_source_name | MATERIAIS 2022 |
| best_oa_location.landing_page_url | https://doi.org/10.3390/materproc2022008082 |
| primary_location.id | doi:10.3390/materproc2022008082 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S4363606122 |
| primary_location.source.issn | |
| primary_location.source.type | conference |
| primary_location.source.is_oa | False |
| primary_location.source.issn_l | |
| primary_location.source.is_core | False |
| primary_location.source.is_in_doaj | False |
| primary_location.source.display_name | MATERIAIS 2022 |
| primary_location.source.host_organization | |
| primary_location.source.host_organization_name | |
| primary_location.source.host_organization_lineage | |
| primary_location.license | cc-by |
| primary_location.pdf_url | https://www.mdpi.com/2673-4605/8/1/82/pdf?version=1654686673 |
| primary_location.version | publishedVersion |
| primary_location.raw_type | proceedings-article |
| primary_location.license_id | https://openalex.org/licenses/cc-by |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | MATERIAIS 2022 |
| primary_location.landing_page_url | https://doi.org/10.3390/materproc2022008082 |
| publication_date | 2022-06-08 |
| publication_year | 2022 |
| referenced_works | https://openalex.org/W3135176824, https://openalex.org/W2904489572, https://openalex.org/W2769858797, https://openalex.org/W3153698673, https://openalex.org/W3000584577, https://openalex.org/W2991103735 |
| referenced_works_count | 6 |
| abstract_inverted_index.* | 88 |
| abstract_inverted_index.1 | 53 |
| abstract_inverted_index.2 | 48, 72 |
| abstract_inverted_index.8 | 115 |
| abstract_inverted_index.A | 698 |
| abstract_inverted_index.B | 627 |
| abstract_inverted_index.a | 145, 207, 353, 544, 547 |
| abstract_inverted_index.e | 546 |
| abstract_inverted_index.1, | 45 |
| abstract_inverted_index.1: | 860 |
| abstract_inverted_index.3D | 28, 321, 799, 822 |
| abstract_inverted_index.8, | 809, 858 |
| abstract_inverted_index.9, | 732 |
| abstract_inverted_index.A. | 39 |
| abstract_inverted_index.Aa | 12, 13, 14 |
| abstract_inverted_index.D. | 83 |
| abstract_inverted_index.F, | 819 |
| abstract_inverted_index.F. | 38, 590, 615, 685, 838 |
| abstract_inverted_index.IP | 899 |
| abstract_inverted_index.J. | 625, 696 |
| abstract_inverted_index.N. | 658, 798, 821 |
| abstract_inverted_index.No | 889, 890 |
| abstract_inverted_index.R. | 43, 841 |
| abstract_inverted_index.an | 282, 375, 692, 765 |
| abstract_inverted_index.as | 281, 419, 438, 903 |
| abstract_inverted_index.at | 98 |
| abstract_inverted_index.be | 94, 240, 327 |
| abstract_inverted_index.by | 36, 169, 269, 540, 622, 755 |
| abstract_inverted_index.de | 66 |
| abstract_inverted_index.in | 212, 301, 329, 470, 636, 747 |
| abstract_inverted_index.is | 219, 266, 278, 324, 374, 764 |
| abstract_inverted_index.it | 218, 333, 379, 473 |
| abstract_inverted_index.no | 578 |
| abstract_inverted_index.of | 62, 78, 124, 140, 192, 215, 253, 256, 304, 338, 341, 391, 428, 478, 534, 574, 580, 592, 639, 666, 687, 719, 775, 872, 880 |
| abstract_inverted_index.on | 202, 346, 367, 446, 480, 596, 722 |
| abstract_inverted_index.or | 159, 167, 598 |
| abstract_inverted_index.si | 403 |
| abstract_inverted_index.to | 90, 121, 144, 151, 222, 239, 242, 289, 312, 326, 407, 422, 458, 530, 617, 662, 744 |
| abstract_inverted_index.© | 753 |
| abstract_inverted_index."3D | 849 |
| abstract_inverted_index.(CC | 780 |
| abstract_inverted_index.1,* | 52 |
| abstract_inverted_index.13, | 604 |
| abstract_inverted_index.18, | 649 |
| abstract_inverted_index.39, | 672 |
| abstract_inverted_index.3DP | 400, 481 |
| abstract_inverted_index.82. | 810, 861 |
| abstract_inverted_index.82; | 112 |
| abstract_inverted_index.A., | 839 |
| abstract_inverted_index.A.; | 586, 611, 679, 709 |
| abstract_inverted_index.ACS | 789 |
| abstract_inverted_index.AMA | 812 |
| abstract_inverted_index.All | 524 |
| abstract_inverted_index.Av. | 81 |
| abstract_inverted_index.BY) | 781 |
| abstract_inverted_index.DNA | 594, 725 |
| abstract_inverted_index.DoE | 616 |
| abstract_inverted_index.F.; | 656, 715, 796 |
| abstract_inverted_index.For | 273 |
| abstract_inverted_index.JR, | 817 |
| abstract_inverted_index.P.; | 584, 713 |
| abstract_inverted_index.PDF | 129 |
| abstract_inverted_index.Rua | 65 |
| abstract_inverted_index.See | 883 |
| abstract_inverted_index.The | 136, 195 |
| abstract_inverted_index.XML | 131 |
| abstract_inverted_index.all | 466 |
| abstract_inverted_index.and | 49, 57, 138, 172, 180, 190, 234, 251, 292, 307, 315, 356, 387, 456, 487, 491, 496, 502, 512, 515, 519, 528, 550, 641, 727, 750, 773, 785, 788, 845 |
| abstract_inverted_index.are | 163, 184, 200, 901 |
| abstract_inverted_index.bed | 264 |
| abstract_inverted_index.can | 299 |
| abstract_inverted_index.for | 30, 55, 147, 187, 801, 824, 851 |
| abstract_inverted_index.has | 442 |
| abstract_inverted_index.its | 225 |
| abstract_inverted_index.low | 302 |
| abstract_inverted_index.no. | 859 |
| abstract_inverted_index.not | 220, 405 |
| abstract_inverted_index.one | 904 |
| abstract_inverted_index.per | 402 |
| abstract_inverted_index.the | 99, 122, 170, 188, 213, 254, 257, 286, 309, 339, 342, 347, 362, 368, 383, 385, 389, 392, 395, 398, 413, 429, 433, 467, 476, 531, 535, 541, 553, 664, 756, 771, 776, 869, 897 |
| abstract_inverted_index.use | 876 |
| abstract_inverted_index.was | 474, 538 |
| abstract_inverted_index.† | 35, 96 |
| abstract_inverted_index. | 17, 18, 19 |
| abstract_inverted_index. | 22, 23, 24 |
| abstract_inverted_index.(Nº | 560 |
| abstract_inverted_index.1,*, | 41 |
| abstract_inverted_index.2022 | 117, 754 |
| abstract_inverted_index.793. | 605 |
| abstract_inverted_index.Cite | 786 |
| abstract_inverted_index.Dias | 44, 816 |
| abstract_inverted_index.Drug | 173 |
| abstract_inverted_index.Eng. | 647 |
| abstract_inverted_index.Epub | 133 |
| abstract_inverted_index.F.S. | 486, 490 |
| abstract_inverted_index.Fani | 46, 843 |
| abstract_inverted_index.Find | 863 |
| abstract_inverted_index.Font | 5, 10 |
| abstract_inverted_index.Food | 171 |
| abstract_inverted_index.J.A. | 717 |
| abstract_inverted_index.JFA, | 815 |
| abstract_inverted_index.June | 116 |
| abstract_inverted_index.Line | 15 |
| abstract_inverted_index.M.T. | 634 |
| abstract_inverted_index.MDPI | 739, 787, 874 |
| abstract_inverted_index.N.A. | 518, 523 |
| abstract_inverted_index.Note | 866 |
| abstract_inverted_index.Nuno | 50, 846 |
| abstract_inverted_index.Open | 26 |
| abstract_inverted_index.Sci. | 730 |
| abstract_inverted_index.This | 373, 762 |
| abstract_inverted_index.[4]. | 372 |
| abstract_inverted_index.bead | 452 |
| abstract_inverted_index.been | 443 |
| abstract_inverted_index.case | 214 |
| abstract_inverted_index.cues | 186 |
| abstract_inverted_index.each | 317 |
| abstract_inverted_index.flow | 359 |
| abstract_inverted_index.from | 868, 896 |
| abstract_inverted_index.full | 336 |
| abstract_inverted_index.gene | 462 |
| abstract_inverted_index.have | 177, 206, 526 |
| abstract_inverted_index.high | 425 |
| abstract_inverted_index.lead | 143, 406 |
| abstract_inverted_index.made | 296 |
| abstract_inverted_index.maps | 749 |
| abstract_inverted_index.more | 354 |
| abstract_inverted_index.most | 196, 434 |
| abstract_inverted_index.need | 310 |
| abstract_inverted_index.open | 766 |
| abstract_inverted_index.page | 881 |
| abstract_inverted_index.para | 543 |
| abstract_inverted_index.path | 360, 390 |
| abstract_inverted_index.pure | 461 |
| abstract_inverted_index.read | 527 |
| abstract_inverted_index.same | 898 |
| abstract_inverted_index.size | 181, 595 |
| abstract_inverted_index.such | 418 |
| abstract_inverted_index.than | 361 |
| abstract_inverted_index.that | 205, 867 |
| abstract_inverted_index.this | 229, 330, 350, 471 |
| abstract_inverted_index.use. | 262 |
| abstract_inverted_index.used | 328 |
| abstract_inverted_index.whom | 91 |
| abstract_inverted_index.will | 380, 404 |
| abstract_inverted_index.with | 294, 415, 742 |
| abstract_inverted_index.work | 537 |
| abstract_inverted_index.(FCT) | 549 |
| abstract_inverted_index.(This | 118 |
| abstract_inverted_index.1105, | 629 |
| abstract_inverted_index.1618, | 700 |
| abstract_inverted_index.2016, | 873 |
| abstract_inverted_index.2017, | 648 |
| abstract_inverted_index.2019, | 628, 731 |
| abstract_inverted_index.2020, | 699 |
| abstract_inverted_index.2021, | 603, 671 |
| abstract_inverted_index.2022) | 126 |
| abstract_inverted_index.2022, | 101, 110, 808 |
| abstract_inverted_index.2022. | 107, 848 |
| abstract_inverted_index.2022; | 831 |
| abstract_inverted_index.5170. | 733 |
| abstract_inverted_index.8(1), | 111 |
| abstract_inverted_index.A.Q.; | 711 |
| abstract_inverted_index.Also, | 211 |
| abstract_inverted_index.Alves | 51, 820 |
| abstract_inverted_index.Appl. | 729 |
| abstract_inverted_index.April | 106 |
| abstract_inverted_index.Arial | 7 |
| abstract_inverted_index.Beira | 79 |
| abstract_inverted_index.Board | 565 |
| abstract_inverted_index.Chem. | 646 |
| abstract_inverted_index.Curr. | 644 |
| abstract_inverted_index.Dias, | 793, 842 |
| abstract_inverted_index.F.S., | 494, 500 |
| abstract_inverted_index.F.S.; | 516, 520 |
| abstract_inverted_index.G.A.; | 681 |
| abstract_inverted_index.G.M.; | 705 |
| abstract_inverted_index.J.A.; | 588, 613, 683 |
| abstract_inverted_index.J.R.; | 794 |
| abstract_inverted_index.Joana | 37, 837 |
| abstract_inverted_index.MATIS | 562 |
| abstract_inverted_index.MDPI, | 759 |
| abstract_inverted_index.Note: | 738 |
| abstract_inverted_index.Notes | 135 |
| abstract_inverted_index.Opin. | 645 |
| abstract_inverted_index.Order | 2 |
| abstract_inverted_index.Other | 864 |
| abstract_inverted_index.Proc. | 109, 807 |
| abstract_inverted_index.Rapid | 56 |
| abstract_inverted_index.Share | 784 |
| abstract_inverted_index.Size: | 11 |
| abstract_inverted_index.Sousa | 47, 818 |
| abstract_inverted_index.Style | 790, 813, 835 |
| abstract_inverted_index.These | 175 |
| abstract_inverted_index.Tools | 661 |
| abstract_inverted_index.Type: | 6 |
| abstract_inverted_index.above | 468 |
| abstract_inverted_index.acids | 421, 437 |
| abstract_inverted_index.allow | 381 |
| abstract_inverted_index.amino | 420, 436 |
| abstract_inverted_index.based | 201 |
| abstract_inverted_index.being | 411 |
| abstract_inverted_index.could | 334 |
| abstract_inverted_index.draft | 508 |
| abstract_inverted_index.extra | 460 |
| abstract_inverted_index.field | 331 |
| abstract_inverted_index.first | 870 |
| abstract_inverted_index.flow, | 384 |
| abstract_inverted_index.fully | 223 |
| abstract_inverted_index.here. | 886 |
| abstract_inverted_index.issue | 871 |
| abstract_inverted_index.leads | 238 |
| abstract_inverted_index.often | 279, 308 |
| abstract_inverted_index.pores | 365 |
| abstract_inverted_index.scope | 288 |
| abstract_inverted_index.since | 332, 378 |
| abstract_inverted_index.stays | 740 |
| abstract_inverted_index.terms | 772 |
| abstract_inverted_index.their | 244 |
| abstract_inverted_index.these | 274 |
| abstract_inverted_index.under | 165, 770 |
| abstract_inverted_index.using | 691 |
| abstract_inverted_index.view. | 905 |
| abstract_inverted_index.which | 162, 183, 247 |
| abstract_inverted_index.work, | 472 |
| abstract_inverted_index.(e.g., | 155 |
| abstract_inverted_index.Access | 892 |
| abstract_inverted_index.Alves, | 657, 797 |
| abstract_inverted_index.Alves. | 847 |
| abstract_inverted_index.Author | 484 |
| abstract_inverted_index.Basel, | 760 |
| abstract_inverted_index.Beyond | 432 |
| abstract_inverted_index.Column | 20 |
| abstract_inverted_index.Effect | 591, 718 |
| abstract_inverted_index.J.R.D. | 495, 501 |
| abstract_inverted_index.Mater. | 108, 806 |
| abstract_inverted_index.Pedro, | 710 |
| abstract_inverted_index.Review | 564 |
| abstract_inverted_index.Sousa, | 585, 589, 610, 614, 655, 678, 684, 708, 714, 795, 844 |
| abstract_inverted_index.Styles | 865 |
| abstract_inverted_index.Trends | 635, 669 |
| abstract_inverted_index.Width: | 21 |
| abstract_inverted_index.access | 767 |
| abstract_inverted_index.acids, | 157 |
| abstract_inverted_index.agreed | 529 |
| abstract_inverted_index.allows | 352 |
| abstract_inverted_index.arises | 311 |
| abstract_inverted_index.before | 261 |
| abstract_inverted_index.claims | 746 |
| abstract_inverted_index.column | 276, 319 |
| abstract_inverted_index.common | 197 |
| abstract_inverted_index.demand | 146 |
| abstract_inverted_index.enable | 423 |
| abstract_inverted_index.field, | 349 |
| abstract_inverted_index.formal | 498 |
| abstract_inverted_index.growth | 139 |
| abstract_inverted_index.levels | 303 |
| abstract_inverted_index.needed | 412 |
| abstract_inverted_index.packed | 258 |
| abstract_inverted_index.porous | 235 |
| abstract_inverted_index.purify | 152 |
| abstract_inverted_index.purity | 426 |
| abstract_inverted_index.regard | 743 |
| abstract_inverted_index.result | 300 |
| abstract_inverted_index.should | 93 |
| abstract_inverted_index.whilst | 285 |
| abstract_inverted_index.within | 394 |
| abstract_inverted_index.yields | 427 |
| abstract_inverted_index.(namely | 450 |
| abstract_inverted_index.10–13 | 105 |
| abstract_inverted_index.460890. | 701 |
| abstract_inverted_index.Article | 3, 887, 891 |
| abstract_inverted_index.Authors | 89 |
| abstract_inverted_index.Centre, | 76 |
| abstract_inverted_index.Commons | 778 |
| abstract_inverted_index.Consent | 568 |
| abstract_inverted_index.Georgia | 8 |
| abstract_inverted_index.Grande, | 70, 103 |
| abstract_inverted_index.Improve | 663 |
| abstract_inverted_index.Infante | 82 |
| abstract_inverted_index.J.F.A.; | 582, 609, 654, 677, 707, 792 |
| abstract_inverted_index.Juliana | 42, 840 |
| abstract_inverted_index.Leiria, | 63, 64 |
| abstract_inverted_index.Marinha | 69, 102 |
| abstract_inverted_index.Metrics | 888 |
| abstract_inverted_index.Product | 59 |
| abstract_inverted_index.Science | 74 |
| abstract_inverted_index.Support | 33, 804, 827, 854 |
| abstract_inverted_index.Valente | 40, 814 |
| abstract_inverted_index.Verdana | 9 |
| abstract_inverted_index.[Google | 606, 631, 651, 674, 702, 734 |
| abstract_inverted_index.achieve | 459 |
| abstract_inverted_index.address | 900 |
| abstract_inverted_index.agarose | 451 |
| abstract_inverted_index.article | 119, 763, 768, 877 |
| abstract_inverted_index.authors | 525, 576 |
| abstract_inverted_index.belongs | 120 |
| abstract_inverted_index.careful | 249 |
| abstract_inverted_index.control | 224, 290, 337 |
| abstract_inverted_index.counted | 902 |
| abstract_inverted_index.declare | 577 |
| abstract_inverted_index.defined | 355 |
| abstract_inverted_index.desired | 153, 430 |
| abstract_inverted_index.details | 885 |
| abstract_inverted_index.enzymes | 158 |
| abstract_inverted_index.funding | 521 |
| abstract_inverted_index.further | 884 |
| abstract_inverted_index.improve | 618 |
| abstract_inverted_index.inexact | 283 |
| abstract_inverted_index.instead | 879 |
| abstract_inverted_index.license | 782 |
| abstract_inverted_index.limited | 287 |
| abstract_inverted_index.methods | 150 |
| abstract_inverted_index.neutral | 741 |
| abstract_inverted_index.nucleic | 156 |
| abstract_inverted_index.numbers | 878 |
| abstract_inverted_index.packing | 277 |
| abstract_inverted_index.pieces. | 344 |
| abstract_inverted_index.plasmid | 593, 690, 724 |
| abstract_inverted_index.predict | 243 |
| abstract_inverted_index.prepare | 314 |
| abstract_inverted_index.provide | 335 |
| abstract_inverted_index.quality | 255 |
| abstract_inverted_index.studied | 435, 475 |
| abstract_inverted_index.support | 371 |
| abstract_inverted_index.testing | 250 |
| abstract_inverted_index.therapy | 463 |
| abstract_inverted_index.through | 552 |
| abstract_inverted_index.treated | 280 |
| abstract_inverted_index.uniform | 357 |
| abstract_inverted_index.version | 533 |
| abstract_inverted_index.022158), | 561 |
| abstract_inverted_index.2430-028 | 68 |
| abstract_inverted_index.6200-506 | 85 |
| abstract_inverted_index.8(1):82. | 832 |
| abstract_inverted_index.90–98. | 650 |
| abstract_inverted_index.Additive | 659 |
| abstract_inverted_index.Affinity | 31, 802, 825, 852 |
| abstract_inverted_index.Azevedo, | 680 |
| abstract_inverted_index.Ciência | 545 |
| abstract_inverted_index.Creative | 777 |
| abstract_inverted_index.Download | 127, 128, 130, 132 |
| abstract_inverted_index.J.F.A.V. | 514 |
| abstract_inverted_index.Licensee | 758 |
| abstract_inverted_index.Multiple | 894 |
| abstract_inverted_index.Pereira, | 583, 712 |
| abstract_inverted_index.Polymers | 602 |
| abstract_inverted_index.Portugal | 71, 87 |
| abstract_inverted_index.Printing | 29, 800, 823, 850 |
| abstract_inverted_index.Queiroz, | 587, 612, 682, 716 |
| abstract_inverted_index.Reprints | 4 |
| abstract_inverted_index.Research | 75 |
| abstract_inverted_index.Scholar] | 607, 632, 652, 675, 703, 735 |
| abstract_inverted_index.Spacing: | 16 |
| abstract_inverted_index.Valente, | 706, 791, 836 |
| abstract_inverted_index.Versions | 134 |
| abstract_inverted_index.additive | 637 |
| abstract_inverted_index.affinity | 416 |
| abstract_inverted_index.approved | 168 |
| abstract_inverted_index.arginine | 441, 479 |
| abstract_inverted_index.authors. | 757 |
| abstract_inverted_index.chemical | 179 |
| abstract_inverted_index.chitosan | 597 |
| abstract_inverted_index.conflict | 579 |
| abstract_inverted_index.critical | 185 |
| abstract_inverted_index.distinct | 178 |
| abstract_inverted_index.editing, | 513 |
| abstract_inverted_index.geometry | 340 |
| abstract_inverted_index.internal | 226, 232 |
| abstract_inverted_index.journals | 875 |
| abstract_inverted_index.ligands, | 417, 440 |
| abstract_inverted_index.matrices | 455 |
| abstract_inverted_index.membrane | 642 |
| abstract_inverted_index.methods. | 272 |
| abstract_inverted_index.numbers. | 882 |
| abstract_inverted_index.observed | 366 |
| abstract_inverted_index.p53-pDNA | 620 |
| abstract_inverted_index.porosity | 293 |
| abstract_inverted_index.possible | 221 |
| abstract_inverted_index.pressure | 386 |
| abstract_inverted_index.printing | 322 |
| abstract_inverted_index.produced | 343 |
| abstract_inverted_index.products | 410, 464 |
| abstract_inverted_index.randomly | 208, 363 |
| abstract_inverted_index.reaching | 424 |
| abstract_inverted_index.reasons, | 275 |
| abstract_inverted_index.requests | 895 |
| abstract_inverted_index.requires | 248 |
| abstract_inverted_index.science, | 284 |
| abstract_inverted_index.settings | 1 |
| abstract_inverted_index.slightly | 230 |
| abstract_inverted_index.starting | 325 |
| abstract_inverted_index.support. | 695 |
| abstract_inverted_index.supports | 199, 260, 449 |
| abstract_inverted_index.validate | 316 |
| abstract_inverted_index.Covilhã, | 86 |
| abstract_inverted_index.Henrique, | 84 |
| abstract_inverted_index.Interior, | 80 |
| abstract_inverted_index.J.F.A.V.; | 488, 492, 497, 503, 505, 510 |
| abstract_inverted_index.MATERIAIS | 125 |
| abstract_inverted_index.Materiais | 100 |
| abstract_inverted_index.Materials | 829, 856 |
| abstract_inverted_index.Moreover, | 263 |
| abstract_inverted_index.Portugal, | 67, 104 |
| abstract_inverted_index.Presented | 97 |
| abstract_inverted_index.Projects: | 555 |
| abstract_inverted_index.analysis, | 499 |
| abstract_inverted_index.behaviour | 246 |
| abstract_inverted_index.compacted | 209 |
| abstract_inverted_index.different | 231, 447 |
| abstract_inverted_index.difficult | 241 |
| abstract_inverted_index.efficient | 148 |
| abstract_inverted_index.empirical | 270 |
| abstract_inverted_index.evaluated | 268 |
| abstract_inverted_index.following | 554 |
| abstract_inverted_index.materials | 204, 298 |
| abstract_inverted_index.matrices, | 453 |
| abstract_inverted_index.molecules | 176, 393 |
| abstract_inverted_index.presented | 237 |
| abstract_inverted_index.presently | 164 |
| abstract_inverted_index.published | 532, 748 |
| abstract_inverted_index.stability | 726 |
| abstract_inverted_index.structure | 227, 236 |
| abstract_inverted_index.supported | 539 |
| abstract_inverted_index.supports, | 217 |
| abstract_inverted_index.supports. | 194, 483 |
| abstract_inverted_index.therapies | 142 |
| abstract_inverted_index.typically | 267 |
| abstract_inverted_index.184–192. | 630 |
| abstract_inverted_index.970–973. | 673 |
| abstract_inverted_index.Centro2020 | 551 |
| abstract_inverted_index.Fundação | 542 |
| abstract_inverted_index.Production | 34 |
| abstract_inverted_index.Published: | 114 |
| abstract_inverted_index.Statistics | 893 |
| abstract_inverted_index.Tecnologia | 548 |
| abstract_inverted_index.Therefore, | 345 |
| abstract_inverted_index.University | 77 |
| abstract_inverted_index.addressed. | 95 |
| abstract_inverted_index.conditions | 721, 774 |
| abstract_inverted_index.convective | 358 |
| abstract_inverted_index.first_page | 0 |
| abstract_inverted_index.materials. | 643 |
| abstract_inverted_index.mentioned, | 469 |
| abstract_inverted_index.modulating | 382 |
| abstract_inverted_index.molecules. | 431 |
| abstract_inverted_index.monoclonal | 160 |
| abstract_inverted_index.monolithic | 216, 297, 318 |
| abstract_inverted_index.monoliths) | 457 |
| abstract_inverted_index.morphology | 233, 291 |
| abstract_inverted_index.polyplexes | 600 |
| abstract_inverted_index.production | 191 |
| abstract_inverted_index.properties | 182 |
| abstract_inverted_index.resources; | 506 |
| abstract_inverted_index.technology | 323, 351 |
| abstract_inverted_index.validation | 252 |
| abstract_inverted_index.Approaches. | 668 |
| abstract_inverted_index.Attribution | 779 |
| abstract_inverted_index.Background: | 25 |
| abstract_inverted_index.Biotechnol. | 670 |
| abstract_inverted_index.Chromatogr. | 626, 697 |
| abstract_inverted_index.InterestThe | 575 |
| abstract_inverted_index.Performance | 665 |
| abstract_inverted_index.Polytechnic | 61 |
| abstract_inverted_index.Proceedings | 123, 857 |
| abstract_inverted_index.Production" | 855 |
| abstract_inverted_index.Production. | 805, 828 |
| abstract_inverted_index.Sustainable | 58 |
| abstract_inverted_index.antibodies) | 161 |
| abstract_inverted_index.association | 414 |
| abstract_inverted_index.development | 137, 189 |
| abstract_inverted_index.distributed | 769 |
| abstract_inverted_index.immobilized | 445 |
| abstract_inverted_index.improvement | 377 |
| abstract_inverted_index.macroporous | 454, 694 |
| abstract_inverted_index.methodology | 489 |
| abstract_inverted_index.supercoiled | 619, 688, 723 |
| abstract_inverted_index.validation, | 493 |
| abstract_inverted_index.Availability | 571 |
| abstract_inverted_index.Development, | 60 |
| abstract_inverted_index.Proceedings. | 830 |
| abstract_inverted_index.Purification | 686 |
| abstract_inverted_index.StatementNot | 566, 569, 572 |
| abstract_inverted_index.Switzerland. | 761 |
| abstract_inverted_index.acquisition, | 522 |
| abstract_inverted_index.bioactivity. | 728 |
| abstract_inverted_index.biomolecules | 154 |
| abstract_inverted_index.consequently | 388 |
| abstract_inverted_index.conventional | 369 |
| abstract_inverted_index.formulation. | 601 |
| abstract_inverted_index.high-quality | 408 |
| abstract_inverted_index.individually | 313 |
| abstract_inverted_index.p53-encoding | 689 |
| abstract_inverted_index.preparation, | 509 |
| abstract_inverted_index.purification | 621 |
| abstract_inverted_index.successfully | 444 |
| abstract_inverted_index.supervision, | 517 |
| abstract_inverted_index.Manufacturing | 660 |
| abstract_inverted_index.affiliations. | 752 |
| abstract_inverted_index.consideration | 166 |
| abstract_inverted_index.consolidation | 265 |
| abstract_inverted_index.extraordinary | 376 |
| abstract_inverted_index.institutional | 751 |
| abstract_inverted_index.manufacturing | 638 |
| abstract_inverted_index.methodologies | 401 |
| abstract_inverted_index.traditionally | 295 |
| abstract_inverted_index.AccessAbstract | 27 |
| abstract_inverted_index.[3].Meanwhile, | 320 |
| abstract_inverted_index.configuration. | 210 |
| abstract_inverted_index.correspondence | 92 |
| abstract_inverted_index.immobilization | 477 |
| abstract_inverted_index.interconnected | 364 |
| abstract_inverted_index.investigation, | 504 |
| abstract_inverted_index.jurisdictional | 745 |
| abstract_inverted_index.pharmaceutical | 409 |
| abstract_inverted_index.Administration. | 174 |
| abstract_inverted_index.Chromatographic | 32, 667, 803, 826, 853 |
| abstract_inverted_index.[5,6].Regarding | 465 |
| abstract_inverted_index.aforementioned, | 399 |
| abstract_inverted_index.applicable.Data | 570 |
| abstract_inverted_index.chromatographic | 149, 193, 198, 245, 259, 348, 370, 396, 439, 448, 482, 640, 720 |
| abstract_inverted_index.chromatography. | 624 |
| abstract_inverted_index.reproducibility | 306 |
| abstract_inverted_index.Chicago/Turabian | 834 |
| abstract_inverted_index.UIDB/00709/2020, | 558 |
| abstract_inverted_index.UIDB/04044/2020, | 556 |
| abstract_inverted_index.UIDP/04044/2020, | 557 |
| abstract_inverted_index.[CrossRef]Hearn, | 633 |
| abstract_inverted_index.[CrossRef][Green | 736 |
| abstract_inverted_index.characterization | 271 |
| abstract_inverted_index.column-to-column | 305 |
| abstract_inverted_index.support.Although | 397 |
| abstract_inverted_index.writing—review | 511 |
| abstract_inverted_index.CICS-UBI—Health | 73 |
| abstract_inverted_index.arginine-modified | 693 |
| abstract_inverted_index.biopharmaceutical | 141 |
| abstract_inverted_index.micro-particulate | 203 |
| abstract_inverted_index.polyethyleneimine | 599 |
| abstract_inverted_index.CDRSP-IPL—Centre | 54 |
| abstract_inverted_index.[1,2].Accordingly, | 228 |
| abstract_inverted_index.[CrossRef]Azevedo, | 704 |
| abstract_inverted_index.[CrossRef]Valente, | 608, 653, 676 |
| abstract_inverted_index.writing—original | 507 |
| abstract_inverted_index.Version]Publisher's | 737 |
| abstract_inverted_index.applicable.Informed | 567 |
| abstract_inverted_index.O-phospho-l-tyrosine | 623 |
| abstract_inverted_index.applicable.Conflicts | 573 |
| abstract_inverted_index.PAMI-ROTEIRO/0328/2013 | 559 |
| abstract_inverted_index.manuscript.FundingThis | 536 |
| abstract_inverted_index.interest.ReferencesValente, | 581 |
| abstract_inverted_index.ContributionsConceptualization, | 485 |
| abstract_inverted_index.https://doi.org/10.3390/materproc2022008082 | 113, 811, 833, 862 |
| abstract_inverted_index.(CEN-TRO-01-0145-FEDER-000014).Institutional | 563 |
| abstract_inverted_index.(https://creativecommons.org/licenses/by/4.0/). | 783 |
| cited_by_percentile_year | |
| corresponding_author_ids | https://openalex.org/A5049046331, https://openalex.org/A5052998969 |
| countries_distinct_count | 1 |
| institutions_distinct_count | 4 |
| corresponding_institution_ids | https://openalex.org/I169427155 |
| citation_normalized_percentile.value | 0.06529879 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |