793 Lead Points and Leaks: Managing Intussusception and Complications in HIV-Driven DLBCL Article Swipe
YOU?
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· 2025
· Open Access
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· DOI: https://doi.org/10.1093/bjs/znaf128.412
Background Intussusception is a rare cause of bowel obstruction in adults responsible for 5% of presentations due to lead points that are often pathological. Identification and treatment of the condition can be challenging as it may be overlooked as a differential, leading to delays in intervention. Case Summary: Here we present the case of a 39-year-old female with HIV-driven DLBCL recently receiving R-CHOP therapy presenting to our ED with nausea, vomiting, abdominal distention and tenderness. Urgent CT imaging revealed characteristic signs of ileocolic intussusception with evidence of upstream bowel obstruction. She underwent an uncomplicated laparoscopic-assisted right hemicolectomy with primary anastomosis and resumed normal bowel habit and oral diet post-operatively. Her recovery was complicated by a chyle leak treated conservatively with dietary modification and supplementary parenteral nutrition. Further complications arose due to persistent tachycardia, tachypnoea, and profound four-limb oedema prompting further management with albumin infusions and diuresis. Unfortunately, her disease continued to progress rapidly with new lymphadenopathy developing, shifting care focus to haematological management. Discussion Heightened caution regarding chyle leaks and significant oedema should be considered in this patient group. This case underscores the need of early identification of postoperative complications in surgical patients with aggressive lymphomas. Conclusions Intussusception in adults warrants high clinical suspicion, especially in patients presenting with risk factors such as malignancy. A multidisciplinary approach alongside careful post-operative monitoring is required to adequately manage complications in high-risk patient groups such as those with aggressive HIV-driven lymphoma.
Related Topics
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1093/bjs/znaf128.412
- https://academic.oup.com/bjs/article-pdf/112/Supplement_10/znaf128.412/63505899/znaf128.412.pdf
- OA Status
- bronze
- Cited By
- 1
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4411680886
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4411680886Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1093/bjs/znaf128.412Digital Object Identifier
- Title
-
793 Lead Points and Leaks: Managing Intussusception and Complications in HIV-Driven DLBCLWork title
- Type
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articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2025Year of publication
- Publication date
-
2025-06-01Full publication date if available
- Authors
-
Bilal Khan, O Kneafsey, Muhammad Aleem Sarwar, Dale PorterList of authors in order
- Landing page
-
https://doi.org/10.1093/bjs/znaf128.412Publisher landing page
- PDF URL
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https://academic.oup.com/bjs/article-pdf/112/Supplement_10/znaf128.412/63505899/znaf128.412.pdfDirect link to full text PDF
- Open access
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YesWhether a free full text is available
- OA status
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bronzeOpen access status per OpenAlex
- OA URL
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https://academic.oup.com/bjs/article-pdf/112/Supplement_10/znaf128.412/63505899/znaf128.412.pdfDirect OA link when available
- Concepts
-
Medicine, Intussusception (medical disorder), Human immunodeficiency virus (HIV), Lead (geology), Intensive care medicine, Surgery, Virology, Geology, GeomorphologyTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
1Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 1Per-year citation counts (last 5 years)
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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| abstract_inverted_index.patients | 193, 207 |
| abstract_inverted_index.profound | 136 |
| abstract_inverted_index.progress | 152 |
| abstract_inverted_index.recently | 61 |
| abstract_inverted_index.recovery | 111 |
| abstract_inverted_index.required | 223 |
| abstract_inverted_index.revealed | 79 |
| abstract_inverted_index.shifting | 158 |
| abstract_inverted_index.surgical | 192 |
| abstract_inverted_index.upstream | 88 |
| abstract_inverted_index.warrants | 201 |
| abstract_inverted_index.abdominal | 72 |
| abstract_inverted_index.alongside | 218 |
| abstract_inverted_index.condition | 30 |
| abstract_inverted_index.continued | 150 |
| abstract_inverted_index.diuresis. | 146 |
| abstract_inverted_index.four-limb | 137 |
| abstract_inverted_index.high-risk | 229 |
| abstract_inverted_index.ileocolic | 83 |
| abstract_inverted_index.infusions | 144 |
| abstract_inverted_index.lymphoma. | 238 |
| abstract_inverted_index.prompting | 139 |
| abstract_inverted_index.receiving | 62 |
| abstract_inverted_index.regarding | 167 |
| abstract_inverted_index.treatment | 27 |
| abstract_inverted_index.underwent | 92 |
| abstract_inverted_index.vomiting, | 71 |
| abstract_inverted_index.Background | 1 |
| abstract_inverted_index.Discussion | 164 |
| abstract_inverted_index.HIV-driven | 59, 237 |
| abstract_inverted_index.Heightened | 165 |
| abstract_inverted_index.adequately | 225 |
| abstract_inverted_index.aggressive | 195, 236 |
| abstract_inverted_index.considered | 175 |
| abstract_inverted_index.distention | 73 |
| abstract_inverted_index.especially | 205 |
| abstract_inverted_index.lymphomas. | 196 |
| abstract_inverted_index.management | 141 |
| abstract_inverted_index.monitoring | 221 |
| abstract_inverted_index.nutrition. | 126 |
| abstract_inverted_index.overlooked | 38 |
| abstract_inverted_index.parenteral | 125 |
| abstract_inverted_index.persistent | 132 |
| abstract_inverted_index.presenting | 65, 208 |
| abstract_inverted_index.suspicion, | 204 |
| abstract_inverted_index.39-year-old | 56 |
| abstract_inverted_index.Conclusions | 197 |
| abstract_inverted_index.anastomosis | 100 |
| abstract_inverted_index.challenging | 33 |
| abstract_inverted_index.complicated | 113 |
| abstract_inverted_index.developing, | 157 |
| abstract_inverted_index.malignancy. | 214 |
| abstract_inverted_index.management. | 163 |
| abstract_inverted_index.obstruction | 9 |
| abstract_inverted_index.responsible | 12 |
| abstract_inverted_index.significant | 171 |
| abstract_inverted_index.tachypnoea, | 134 |
| abstract_inverted_index.tenderness. | 75 |
| abstract_inverted_index.underscores | 182 |
| abstract_inverted_index.modification | 122 |
| abstract_inverted_index.obstruction. | 90 |
| abstract_inverted_index.tachycardia, | 133 |
| abstract_inverted_index.complications | 128, 190, 227 |
| abstract_inverted_index.differential, | 41 |
| abstract_inverted_index.hemicolectomy | 97 |
| abstract_inverted_index.intervention. | 46 |
| abstract_inverted_index.pathological. | 24 |
| abstract_inverted_index.postoperative | 189 |
| abstract_inverted_index.presentations | 16 |
| abstract_inverted_index.supplementary | 124 |
| abstract_inverted_index.uncomplicated | 94 |
| abstract_inverted_index.Identification | 25 |
| abstract_inverted_index.Unfortunately, | 147 |
| abstract_inverted_index.characteristic | 80 |
| abstract_inverted_index.conservatively | 119 |
| abstract_inverted_index.haematological | 162 |
| abstract_inverted_index.identification | 187 |
| abstract_inverted_index.post-operative | 220 |
| abstract_inverted_index.Intussusception | 2, 198 |
| abstract_inverted_index.intussusception | 84 |
| abstract_inverted_index.lymphadenopathy | 156 |
| abstract_inverted_index.multidisciplinary | 216 |
| abstract_inverted_index.post-operatively. | 109 |
| abstract_inverted_index.laparoscopic-assisted | 95 |
| cited_by_percentile_year.max | 95 |
| cited_by_percentile_year.min | 91 |
| countries_distinct_count | 1 |
| institutions_distinct_count | 4 |
| citation_normalized_percentile.value | 0.88129467 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | True |