A-100 A Mini-Meta Analysis on Alzheimer’s Disease and Aggression/Agitation Behaviors Article Swipe
Adrianna C Gallegos
,
M D Shields
,
Gage Singer
,
Rachel E. Thayer
·
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.1093/arclin/acac060.100
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.1093/arclin/acac060.100
Objective: This meta-analysis used primary studies that examined gender differences and behavior disturbances observed in Alzheimer’s disease (ad). Aggression/agitation behaviors become prevalent in advanced cases, with anxiety and problematic conduct more likely in men and sleep and mood disturbances in women, which can adversely impact cognition, rate of decline, and functionality (Lee et al., 2017). Therefore, this analysis hypothesized that men with ad are more likely to report aggression/agitation symptomology than women. Data Selection: Inclusionary criteria of primary studies (N = 6) dictated that each must have researched ad samples, included measures of aggression/agitation, and reported mean differences between genders, allowing for Cohen’s d calculations, with searches conducted in February 2022. Cohen’s d was used for summary effects. Data Synthesis: This analysis utilized a weighted random-effects model for summary synthesis. This model effectively synthesizes real-world data because it assumes variation in estimates comes from multiple sources rather than one true value, indicating heterogeneity. The resulting summary effect (N = 1575, Cohen’s d = 0.09, Z test = 1.24, p-value = 0.213) indicated statistical non-significance, such that gender differences were not observed on average. Conclusions: This analysis suggests that differences between gender and aggressive/agitated behavior are not robust. Mixed results among the primary studies suggest that gender differences may exist in ad-related behavior. Still, few studies met the inclusion criteria of this analysis as they did not examine or provide mean differences for gender or provide data required to calculate an effect size. Future research should include other facets of behavior for a more comprehensive meta-analysis.
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Concepts
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1093/arclin/acac060.100
- https://academic.oup.com/acn/article-pdf/37/6/1252/45498596/acac060.100.pdf
- OA Status
- bronze
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4292089174
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4292089174Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1093/arclin/acac060.100Digital Object Identifier
- Title
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A-100 A Mini-Meta Analysis on Alzheimer’s Disease and Aggression/Agitation BehaviorsWork title
- Type
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articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2022Year of publication
- Publication date
-
2022-08-17Full publication date if available
- Authors
-
Adrianna C Gallegos, M D Shields, Gage Singer, Rachel E. ThayerList of authors in order
- Landing page
-
https://doi.org/10.1093/arclin/acac060.100Publisher landing page
- PDF URL
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https://academic.oup.com/acn/article-pdf/37/6/1252/45498596/acac060.100.pdfDirect link to full text PDF
- Open access
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YesWhether a free full text is available
- OA status
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bronzeOpen access status per OpenAlex
- OA URL
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https://academic.oup.com/acn/article-pdf/37/6/1252/45498596/acac060.100.pdfDirect OA link when available
- Concepts
-
Aggression, Psychology, Meta-analysis, Anxiety, Mood, Clinical psychology, Disease, Developmental psychology, Psychiatry, Medicine, Internal medicineTop concepts (fields/topics) attached by OpenAlex
- Cited by
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0Total citation count in OpenAlex
- Related works (count)
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10Other works algorithmically related by OpenAlex
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| abstract_inverted_index.Objective: | 1 |
| abstract_inverted_index.Selection: | 74 |
| abstract_inverted_index.Synthesis: | 120 |
| abstract_inverted_index.Therefore, | 56 |
| abstract_inverted_index.ad-related | 211 |
| abstract_inverted_index.cognition, | 46 |
| abstract_inverted_index.indicating | 152 |
| abstract_inverted_index.real-world | 135 |
| abstract_inverted_index.researched | 88 |
| abstract_inverted_index.synthesis. | 130 |
| abstract_inverted_index.differences | 10, 98, 178, 189, 207, 231 |
| abstract_inverted_index.effectively | 133 |
| abstract_inverted_index.problematic | 29 |
| abstract_inverted_index.statistical | 173 |
| abstract_inverted_index.synthesizes | 134 |
| abstract_inverted_index.Conclusions: | 184 |
| abstract_inverted_index.Inclusionary | 75 |
| abstract_inverted_index.disturbances | 13, 39 |
| abstract_inverted_index.hypothesized | 59 |
| abstract_inverted_index.symptomology | 70 |
| abstract_inverted_index.Alzheimer’s | 16 |
| abstract_inverted_index.calculations, | 105 |
| abstract_inverted_index.comprehensive | 254 |
| abstract_inverted_index.functionality | 51 |
| abstract_inverted_index.meta-analysis | 3 |
| abstract_inverted_index.heterogeneity. | 153 |
| abstract_inverted_index.meta-analysis. | 255 |
| abstract_inverted_index.random-effects | 126 |
| abstract_inverted_index.non-significance, | 174 |
| abstract_inverted_index.aggressive/agitated | 193 |
| abstract_inverted_index.Aggression/agitation | 19 |
| abstract_inverted_index.aggression/agitation | 69 |
| abstract_inverted_index.aggression/agitation, | 94 |
| cited_by_percentile_year | |
| countries_distinct_count | 0 |
| institutions_distinct_count | 4 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/5 |
| sustainable_development_goals[0].score | 0.4099999964237213 |
| sustainable_development_goals[0].display_name | Gender equality |
| citation_normalized_percentile.value | 0.16613141 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |