A 15-year study of neuraminidase mutations and the increasing of S247N mutation in Spain Article Swipe
Iván Sanz-Muñoz
,
Alejandro Martín-Toribio
,
Adrián García-Concejo
,
Irene Arroyo-Hernantes
,
Marina Toquero-Asensio
,
Javier Sánchez‐Martínez
,
Carla Rodríguez-Crespo
,
Silvia Rojo‐Rello
,
Marta Domínguez-Gil González
,
Eduardo Tamayo
,
Marier Hernández‐Pérez
,
José María Eirós Bouza
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1016/j.virusres.2025.199599
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1016/j.virusres.2025.199599
The therapeutic arsenal against influenza is extremely limited and resistance often arises due to the emergence of mutations, especially in the neuraminidase (NA) gene. This study aimed to evaluate the evolution of NA mutations over 15 years in Spain. To do so, we used the GISAID database from which we downloaded a total of 11,125 influenza A(H1N1)pdm09, A(H3N2), B/Victoria and B/Yamagata NA virus sequences, and analyzed the resistance mutations using FluSurver software. Our results showed that the occurrence of NA resistance mutations remained constant in the four viruses during the 15 seasons evaluated, being around 0.5-5 %. Most of the resistance was found in the A(H1N1)pdm09 subtype (around 70 %), especially from the 2023-2024 season onwards, when a significant increase in the occurrence of S247N mutation was observed. The occurrence of this type of mutation before 2022 was rare, but in the 2023-2024 season a total of 44 influenza viruses harboring S247N mutations were detected, while in the other years, only two cases were observed. Some studies have described a significant increase in this mutation over the past two seasons and although it appears to confer only slightly reduced inhibition to oseltamivir, its increase is noteworthy and should be a reason for increased their vigilance.
Related Topics
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1016/j.virusres.2025.199599
- OA Status
- gold
- References
- 33
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4411701996
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4411701996Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1016/j.virusres.2025.199599Digital Object Identifier
- Title
-
A 15-year study of neuraminidase mutations and the increasing of S247N mutation in SpainWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2025Year of publication
- Publication date
-
2025-06-26Full publication date if available
- Authors
-
Iván Sanz-Muñoz, Alejandro Martín-Toribio, Adrián García-Concejo, Irene Arroyo-Hernantes, Marina Toquero-Asensio, Javier Sánchez‐Martínez, Carla Rodríguez-Crespo, Silvia Rojo‐Rello, Marta Domínguez-Gil González, Eduardo Tamayo, Marier Hernández‐Pérez, José María Eirós BouzaList of authors in order
- Landing page
-
https://doi.org/10.1016/j.virusres.2025.199599Publisher landing page
- Open access
-
YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
-
https://doi.org/10.1016/j.virusres.2025.199599Direct OA link when available
- Concepts
-
Biology, Mutation, Genetics, Neuraminidase, Gene, VirusTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
0Total citation count in OpenAlex
- References (count)
-
33Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W4411701996 |
|---|---|
| doi | https://doi.org/10.1016/j.virusres.2025.199599 |
| ids.doi | https://doi.org/10.1016/j.virusres.2025.199599 |
| ids.pmid | https://pubmed.ncbi.nlm.nih.gov/40581106 |
| ids.openalex | https://openalex.org/W4411701996 |
| fwci | 0.0 |
| mesh[0].qualifier_ui | Q000235 |
| mesh[0].descriptor_ui | D009439 |
| mesh[0].is_major_topic | True |
| mesh[0].qualifier_name | genetics |
| mesh[0].descriptor_name | Neuraminidase |
| mesh[1].qualifier_ui | Q000453 |
| mesh[1].descriptor_ui | D013030 |
| mesh[1].is_major_topic | False |
| mesh[1].qualifier_name | epidemiology |
| mesh[1].descriptor_name | Spain |
| mesh[2].qualifier_ui | |
| mesh[2].descriptor_ui | D006801 |
| mesh[2].is_major_topic | False |
| mesh[2].qualifier_name | |
| mesh[2].descriptor_name | Humans |
| mesh[3].qualifier_ui | Q000235 |
| mesh[3].descriptor_ui | D024882 |
| mesh[3].is_major_topic | True |
| mesh[3].qualifier_name | genetics |
| mesh[3].descriptor_name | Drug Resistance, Viral |
| mesh[4].qualifier_ui | Q000821 |
| mesh[4].descriptor_ui | D007251 |
| mesh[4].is_major_topic | True |
| mesh[4].qualifier_name | virology |
| mesh[4].descriptor_name | Influenza, Human |
| mesh[5].qualifier_ui | Q000453 |
| mesh[5].descriptor_ui | D007251 |
| mesh[5].is_major_topic | True |
| mesh[5].qualifier_name | epidemiology |
| mesh[5].descriptor_name | Influenza, Human |
| mesh[6].qualifier_ui | |
| mesh[6].descriptor_ui | D009154 |
| mesh[6].is_major_topic | True |
| mesh[6].qualifier_name | |
| mesh[6].descriptor_name | Mutation |
| mesh[7].qualifier_ui | Q000494 |
| mesh[7].descriptor_ui | D000998 |
| mesh[7].is_major_topic | False |
| mesh[7].qualifier_name | pharmacology |
| mesh[7].descriptor_name | Antiviral Agents |
| mesh[8].qualifier_ui | Q000235 |
| mesh[8].descriptor_ui | D014764 |
| mesh[8].is_major_topic | True |
| mesh[8].qualifier_name | genetics |
| mesh[8].descriptor_name | Viral Proteins |
| mesh[9].qualifier_ui | Q000235 |
| mesh[9].descriptor_ui | D053122 |
| mesh[9].is_major_topic | False |
| mesh[9].qualifier_name | genetics |
| mesh[9].descriptor_name | Influenza A Virus, H3N2 Subtype |
| mesh[10].qualifier_ui | Q000187 |
| mesh[10].descriptor_ui | D053122 |
| mesh[10].is_major_topic | False |
| mesh[10].qualifier_name | drug effects |
| mesh[10].descriptor_name | Influenza A Virus, H3N2 Subtype |
| mesh[11].qualifier_ui | Q000201 |
| mesh[11].descriptor_ui | D053122 |
| mesh[11].is_major_topic | False |
| mesh[11].qualifier_name | enzymology |
| mesh[11].descriptor_name | Influenza A Virus, H3N2 Subtype |
| mesh[12].qualifier_ui | Q000235 |
| mesh[12].descriptor_ui | D053118 |
| mesh[12].is_major_topic | False |
| mesh[12].qualifier_name | genetics |
| mesh[12].descriptor_name | Influenza A Virus, H1N1 Subtype |
| mesh[13].qualifier_ui | Q000187 |
| mesh[13].descriptor_ui | D053118 |
| mesh[13].is_major_topic | False |
| mesh[13].qualifier_name | drug effects |
| mesh[13].descriptor_name | Influenza A Virus, H1N1 Subtype |
| mesh[14].qualifier_ui | Q000201 |
| mesh[14].descriptor_ui | D053118 |
| mesh[14].is_major_topic | False |
| mesh[14].qualifier_name | enzymology |
| mesh[14].descriptor_name | Influenza A Virus, H1N1 Subtype |
| mesh[15].qualifier_ui | Q000235 |
| mesh[15].descriptor_ui | D009981 |
| mesh[15].is_major_topic | True |
| mesh[15].qualifier_name | genetics |
| mesh[15].descriptor_name | Influenza B virus |
| mesh[16].qualifier_ui | Q000187 |
| mesh[16].descriptor_ui | D009981 |
| mesh[16].is_major_topic | True |
| mesh[16].qualifier_name | drug effects |
| mesh[16].descriptor_name | Influenza B virus |
| mesh[17].qualifier_ui | Q000201 |
| mesh[17].descriptor_ui | D009981 |
| mesh[17].is_major_topic | True |
| mesh[17].qualifier_name | enzymology |
| mesh[17].descriptor_name | Influenza B virus |
| mesh[18].qualifier_ui | |
| mesh[18].descriptor_ui | D012621 |
| mesh[18].is_major_topic | False |
| mesh[18].qualifier_name | |
| mesh[18].descriptor_name | Seasons |
| mesh[19].qualifier_ui | Q000235 |
| mesh[19].descriptor_ui | D009439 |
| mesh[19].is_major_topic | True |
| mesh[19].qualifier_name | genetics |
| mesh[19].descriptor_name | Neuraminidase |
| mesh[20].qualifier_ui | Q000453 |
| mesh[20].descriptor_ui | D013030 |
| mesh[20].is_major_topic | False |
| mesh[20].qualifier_name | epidemiology |
| mesh[20].descriptor_name | Spain |
| mesh[21].qualifier_ui | |
| mesh[21].descriptor_ui | D006801 |
| mesh[21].is_major_topic | False |
| mesh[21].qualifier_name | |
| mesh[21].descriptor_name | Humans |
| mesh[22].qualifier_ui | Q000235 |
| mesh[22].descriptor_ui | D024882 |
| mesh[22].is_major_topic | True |
| mesh[22].qualifier_name | genetics |
| mesh[22].descriptor_name | Drug Resistance, Viral |
| mesh[23].qualifier_ui | Q000821 |
| mesh[23].descriptor_ui | D007251 |
| mesh[23].is_major_topic | True |
| mesh[23].qualifier_name | virology |
| mesh[23].descriptor_name | Influenza, Human |
| mesh[24].qualifier_ui | Q000453 |
| mesh[24].descriptor_ui | D007251 |
| mesh[24].is_major_topic | True |
| mesh[24].qualifier_name | epidemiology |
| mesh[24].descriptor_name | Influenza, Human |
| mesh[25].qualifier_ui | |
| mesh[25].descriptor_ui | D009154 |
| mesh[25].is_major_topic | True |
| mesh[25].qualifier_name | |
| mesh[25].descriptor_name | Mutation |
| mesh[26].qualifier_ui | Q000494 |
| mesh[26].descriptor_ui | D000998 |
| mesh[26].is_major_topic | False |
| mesh[26].qualifier_name | pharmacology |
| mesh[26].descriptor_name | Antiviral Agents |
| mesh[27].qualifier_ui | Q000235 |
| mesh[27].descriptor_ui | D014764 |
| mesh[27].is_major_topic | True |
| mesh[27].qualifier_name | genetics |
| mesh[27].descriptor_name | Viral Proteins |
| mesh[28].qualifier_ui | Q000235 |
| mesh[28].descriptor_ui | D053122 |
| mesh[28].is_major_topic | False |
| mesh[28].qualifier_name | genetics |
| mesh[28].descriptor_name | Influenza A Virus, H3N2 Subtype |
| mesh[29].qualifier_ui | Q000187 |
| mesh[29].descriptor_ui | D053122 |
| mesh[29].is_major_topic | False |
| mesh[29].qualifier_name | drug effects |
| mesh[29].descriptor_name | Influenza A Virus, H3N2 Subtype |
| mesh[30].qualifier_ui | Q000201 |
| mesh[30].descriptor_ui | D053122 |
| mesh[30].is_major_topic | False |
| mesh[30].qualifier_name | enzymology |
| mesh[30].descriptor_name | Influenza A Virus, H3N2 Subtype |
| mesh[31].qualifier_ui | Q000235 |
| mesh[31].descriptor_ui | D053118 |
| mesh[31].is_major_topic | False |
| mesh[31].qualifier_name | genetics |
| mesh[31].descriptor_name | Influenza A Virus, H1N1 Subtype |
| mesh[32].qualifier_ui | Q000187 |
| mesh[32].descriptor_ui | D053118 |
| mesh[32].is_major_topic | False |
| mesh[32].qualifier_name | drug effects |
| mesh[32].descriptor_name | Influenza A Virus, H1N1 Subtype |
| mesh[33].qualifier_ui | Q000201 |
| mesh[33].descriptor_ui | D053118 |
| mesh[33].is_major_topic | False |
| mesh[33].qualifier_name | enzymology |
| mesh[33].descriptor_name | Influenza A Virus, H1N1 Subtype |
| mesh[34].qualifier_ui | Q000235 |
| mesh[34].descriptor_ui | D009981 |
| mesh[34].is_major_topic | True |
| mesh[34].qualifier_name | genetics |
| mesh[34].descriptor_name | Influenza B virus |
| mesh[35].qualifier_ui | Q000187 |
| mesh[35].descriptor_ui | D009981 |
| mesh[35].is_major_topic | True |
| mesh[35].qualifier_name | drug effects |
| mesh[35].descriptor_name | Influenza B virus |
| mesh[36].qualifier_ui | Q000201 |
| mesh[36].descriptor_ui | D009981 |
| mesh[36].is_major_topic | True |
| mesh[36].qualifier_name | enzymology |
| mesh[36].descriptor_name | Influenza B virus |
| mesh[37].qualifier_ui | |
| mesh[37].descriptor_ui | D012621 |
| mesh[37].is_major_topic | False |
| mesh[37].qualifier_name | |
| mesh[37].descriptor_name | Seasons |
| type | article |
| title | A 15-year study of neuraminidase mutations and the increasing of S247N mutation in Spain |
| biblio.issue | |
| biblio.volume | 358 |
| biblio.last_page | 199599 |
| biblio.first_page | 199599 |
| topics[0].id | https://openalex.org/T10167 |
| topics[0].field.id | https://openalex.org/fields/27 |
| topics[0].field.display_name | Medicine |
| topics[0].score | 0.9975000023841858 |
| topics[0].domain.id | https://openalex.org/domains/4 |
| topics[0].domain.display_name | Health Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/2713 |
| topics[0].subfield.display_name | Epidemiology |
| topics[0].display_name | Influenza Virus Research Studies |
| topics[1].id | https://openalex.org/T10943 |
| topics[1].field.id | https://openalex.org/fields/13 |
| topics[1].field.display_name | Biochemistry, Genetics and Molecular Biology |
| topics[1].score | 0.9973000288009644 |
| topics[1].domain.id | https://openalex.org/domains/1 |
| topics[1].domain.display_name | Life Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/1310 |
| topics[1].subfield.display_name | Endocrinology |
| topics[1].display_name | Escherichia coli research studies |
| topics[2].id | https://openalex.org/T10602 |
| topics[2].field.id | https://openalex.org/fields/13 |
| topics[2].field.display_name | Biochemistry, Genetics and Molecular Biology |
| topics[2].score | 0.9965000152587891 |
| topics[2].domain.id | https://openalex.org/domains/1 |
| topics[2].domain.display_name | Life Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/1312 |
| topics[2].subfield.display_name | Molecular Biology |
| topics[2].display_name | Glycosylation and Glycoproteins Research |
| is_xpac | False |
| apc_list.value | 2650 |
| apc_list.currency | USD |
| apc_list.value_usd | 2650 |
| apc_paid.value | 2650 |
| apc_paid.currency | USD |
| apc_paid.value_usd | 2650 |
| concepts[0].id | https://openalex.org/C86803240 |
| concepts[0].level | 0 |
| concepts[0].score | 0.9260779619216919 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q420 |
| concepts[0].display_name | Biology |
| concepts[1].id | https://openalex.org/C501734568 |
| concepts[1].level | 3 |
| concepts[1].score | 0.6927849054336548 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q42918 |
| concepts[1].display_name | Mutation |
| concepts[2].id | https://openalex.org/C54355233 |
| concepts[2].level | 1 |
| concepts[2].score | 0.6490854620933533 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q7162 |
| concepts[2].display_name | Genetics |
| concepts[3].id | https://openalex.org/C134164806 |
| concepts[3].level | 3 |
| concepts[3].score | 0.6426352858543396 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q409485 |
| concepts[3].display_name | Neuraminidase |
| concepts[4].id | https://openalex.org/C104317684 |
| concepts[4].level | 2 |
| concepts[4].score | 0.16450491547584534 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q7187 |
| concepts[4].display_name | Gene |
| concepts[5].id | https://openalex.org/C2522874641 |
| concepts[5].level | 2 |
| concepts[5].score | 0.030461788177490234 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q808 |
| concepts[5].display_name | Virus |
| keywords[0].id | https://openalex.org/keywords/biology |
| keywords[0].score | 0.9260779619216919 |
| keywords[0].display_name | Biology |
| keywords[1].id | https://openalex.org/keywords/mutation |
| keywords[1].score | 0.6927849054336548 |
| keywords[1].display_name | Mutation |
| keywords[2].id | https://openalex.org/keywords/genetics |
| keywords[2].score | 0.6490854620933533 |
| keywords[2].display_name | Genetics |
| keywords[3].id | https://openalex.org/keywords/neuraminidase |
| keywords[3].score | 0.6426352858543396 |
| keywords[3].display_name | Neuraminidase |
| keywords[4].id | https://openalex.org/keywords/gene |
| keywords[4].score | 0.16450491547584534 |
| keywords[4].display_name | Gene |
| keywords[5].id | https://openalex.org/keywords/virus |
| keywords[5].score | 0.030461788177490234 |
| keywords[5].display_name | Virus |
| language | en |
| locations[0].id | doi:10.1016/j.virusres.2025.199599 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S114911520 |
| locations[0].source.issn | 0168-1702, 1872-7492 |
| locations[0].source.type | journal |
| locations[0].source.is_oa | True |
| locations[0].source.issn_l | 0168-1702 |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | True |
| locations[0].source.display_name | Virus Research |
| locations[0].source.host_organization | https://openalex.org/P4310320990 |
| locations[0].source.host_organization_name | Elsevier BV |
| locations[0].source.host_organization_lineage | https://openalex.org/P4310320990 |
| locations[0].license | cc-by-nc-nd |
| locations[0].pdf_url | |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | https://openalex.org/licenses/cc-by-nc-nd |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | Virus Research |
| locations[0].landing_page_url | https://doi.org/10.1016/j.virusres.2025.199599 |
| locations[1].id | pmid:40581106 |
| locations[1].is_oa | False |
| locations[1].source.id | https://openalex.org/S4306525036 |
| locations[1].source.issn | |
| locations[1].source.type | repository |
| locations[1].source.is_oa | False |
| locations[1].source.issn_l | |
| locations[1].source.is_core | False |
| locations[1].source.is_in_doaj | False |
| locations[1].source.display_name | PubMed |
| locations[1].source.host_organization | https://openalex.org/I1299303238 |
| locations[1].source.host_organization_name | National Institutes of Health |
| locations[1].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[1].license | |
| locations[1].pdf_url | |
| locations[1].version | publishedVersion |
| locations[1].raw_type | |
| locations[1].license_id | |
| locations[1].is_accepted | True |
| locations[1].is_published | True |
| locations[1].raw_source_name | Virus research |
| locations[1].landing_page_url | https://pubmed.ncbi.nlm.nih.gov/40581106 |
| locations[2].id | pmh:oai:doaj.org/article:28348039990a4ce2beb6109d04ec4b8f |
| locations[2].is_oa | True |
| locations[2].source.id | https://openalex.org/S4306401280 |
| locations[2].source.issn | |
| locations[2].source.type | repository |
| locations[2].source.is_oa | False |
| locations[2].source.issn_l | |
| locations[2].source.is_core | False |
| locations[2].source.is_in_doaj | False |
| locations[2].source.display_name | DOAJ (DOAJ: Directory of Open Access Journals) |
| locations[2].source.host_organization | |
| locations[2].source.host_organization_name | |
| locations[2].source.host_organization_lineage | |
| locations[2].license | cc-by-sa |
| locations[2].pdf_url | |
| locations[2].version | submittedVersion |
| locations[2].raw_type | article |
| locations[2].license_id | https://openalex.org/licenses/cc-by-sa |
| locations[2].is_accepted | False |
| locations[2].is_published | False |
| locations[2].raw_source_name | Virus Research, Vol 358, Iss , Pp 199599- (2025) |
| locations[2].landing_page_url | https://doaj.org/article/28348039990a4ce2beb6109d04ec4b8f |
| locations[3].id | pmh:oai:pubmedcentral.nih.gov:12270646 |
| locations[3].is_oa | True |
| locations[3].source.id | https://openalex.org/S2764455111 |
| locations[3].source.issn | |
| locations[3].source.type | repository |
| locations[3].source.is_oa | False |
| locations[3].source.issn_l | |
| locations[3].source.is_core | False |
| locations[3].source.is_in_doaj | False |
| locations[3].source.display_name | PubMed Central |
| locations[3].source.host_organization | https://openalex.org/I1299303238 |
| locations[3].source.host_organization_name | National Institutes of Health |
| locations[3].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[3].license | other-oa |
| locations[3].pdf_url | |
| locations[3].version | submittedVersion |
| locations[3].raw_type | Text |
| locations[3].license_id | https://openalex.org/licenses/other-oa |
| locations[3].is_accepted | False |
| locations[3].is_published | False |
| locations[3].raw_source_name | Virus Res |
| locations[3].landing_page_url | https://www.ncbi.nlm.nih.gov/pmc/articles/12270646 |
| indexed_in | crossref, doaj, pubmed |
| authorships[0].author.id | https://openalex.org/A5074373469 |
| authorships[0].author.orcid | https://orcid.org/0000-0003-4725-6663 |
| authorships[0].author.display_name | Iván Sanz-Muñoz |
| authorships[0].countries | ES |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I4210094790, https://openalex.org/I4210115082 |
| authorships[0].affiliations[0].raw_affiliation_string | National Influenza Centre, Valladolid, Spain; Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León, Soria, Spain; Centro de Investigación Biomédica en Red de Enfermedades Infecciosas (CIBERINFEC), Madrid, Spain. Electronic address: [email protected]. |
| authorships[0].institutions[0].id | https://openalex.org/I4210115082 |
| authorships[0].institutions[0].ror | https://ror.org/02g87qh62 |
| authorships[0].institutions[0].type | facility |
| authorships[0].institutions[0].lineage | https://openalex.org/I2801357902, https://openalex.org/I4210115082, https://openalex.org/I4387152914 |
| authorships[0].institutions[0].country_code | ES |
| authorships[0].institutions[0].display_name | Centro de Investigación Biomédica en Red |
| authorships[0].institutions[1].id | https://openalex.org/I4210094790 |
| authorships[0].institutions[1].ror | https://ror.org/00vn23s59 |
| authorships[0].institutions[1].type | nonprofit |
| authorships[0].institutions[1].lineage | https://openalex.org/I4210094790 |
| authorships[0].institutions[1].country_code | ES |
| authorships[0].institutions[1].display_name | Instituto de Estudios de Ciencias de la Salud de Castilla y León |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Iván Sanz-Muñoz |
| authorships[0].is_corresponding | False |
| authorships[0].raw_affiliation_strings | National Influenza Centre, Valladolid, Spain; Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León, Soria, Spain; Centro de Investigación Biomédica en Red de Enfermedades Infecciosas (CIBERINFEC), Madrid, Spain. Electronic address: [email protected]. |
| authorships[1].author.id | https://openalex.org/A5093891668 |
| authorships[1].author.orcid | https://orcid.org/0000-0001-7664-4433 |
| authorships[1].author.display_name | Alejandro Martín-Toribio |
| authorships[1].countries | ES |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I108103353 |
| authorships[1].affiliations[0].raw_affiliation_string | National Influenza Centre, Valladolid, Spain; Faculty of Medicine, Universidad de Valladolid, Spain. |
| authorships[1].institutions[0].id | https://openalex.org/I108103353 |
| authorships[1].institutions[0].ror | https://ror.org/01fvbaw18 |
| authorships[1].institutions[0].type | education |
| authorships[1].institutions[0].lineage | https://openalex.org/I108103353 |
| authorships[1].institutions[0].country_code | ES |
| authorships[1].institutions[0].display_name | Universidad de Valladolid |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Alejandro Martín-Toribio |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | National Influenza Centre, Valladolid, Spain; Faculty of Medicine, Universidad de Valladolid, Spain. |
| authorships[2].author.id | https://openalex.org/A5099099319 |
| authorships[2].author.orcid | |
| authorships[2].author.display_name | Adrián García-Concejo |
| authorships[2].countries | ES |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I4210115082 |
| authorships[2].affiliations[0].raw_affiliation_string | Centro de Investigación Biomédica en Red de Enfermedades Infecciosas (CIBERINFEC), Madrid, Spain; Grupo de Investigación en Biomedicina en Cuidados Críticos, BioCritic, Valladolid, Spain. |
| authorships[2].institutions[0].id | https://openalex.org/I4210115082 |
| authorships[2].institutions[0].ror | https://ror.org/02g87qh62 |
| authorships[2].institutions[0].type | facility |
| authorships[2].institutions[0].lineage | https://openalex.org/I2801357902, https://openalex.org/I4210115082, https://openalex.org/I4387152914 |
| authorships[2].institutions[0].country_code | ES |
| authorships[2].institutions[0].display_name | Centro de Investigación Biomédica en Red |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Adrián García-Concejo |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | Centro de Investigación Biomédica en Red de Enfermedades Infecciosas (CIBERINFEC), Madrid, Spain; Grupo de Investigación en Biomedicina en Cuidados Críticos, BioCritic, Valladolid, Spain. |
| authorships[3].author.id | https://openalex.org/A5094284954 |
| authorships[3].author.orcid | https://orcid.org/0009-0000-3746-6187 |
| authorships[3].author.display_name | Irene Arroyo-Hernantes |
| authorships[3].countries | ES |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I4210094790 |
| authorships[3].affiliations[0].raw_affiliation_string | National Influenza Centre, Valladolid, Spain; Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León, Soria, Spain. |
| authorships[3].institutions[0].id | https://openalex.org/I4210094790 |
| authorships[3].institutions[0].ror | https://ror.org/00vn23s59 |
| authorships[3].institutions[0].type | nonprofit |
| authorships[3].institutions[0].lineage | https://openalex.org/I4210094790 |
| authorships[3].institutions[0].country_code | ES |
| authorships[3].institutions[0].display_name | Instituto de Estudios de Ciencias de la Salud de Castilla y León |
| authorships[3].author_position | middle |
| authorships[3].raw_author_name | Irene Arroyo-Hernantes |
| authorships[3].is_corresponding | False |
| authorships[3].raw_affiliation_strings | National Influenza Centre, Valladolid, Spain; Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León, Soria, Spain. |
| authorships[4].author.id | https://openalex.org/A5092930603 |
| authorships[4].author.orcid | https://orcid.org/0009-0005-4569-6755 |
| authorships[4].author.display_name | Marina Toquero-Asensio |
| authorships[4].countries | ES |
| authorships[4].affiliations[0].institution_ids | https://openalex.org/I4210094790 |
| authorships[4].affiliations[0].raw_affiliation_string | National Influenza Centre, Valladolid, Spain; Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León, Soria, Spain. |
| authorships[4].institutions[0].id | https://openalex.org/I4210094790 |
| authorships[4].institutions[0].ror | https://ror.org/00vn23s59 |
| authorships[4].institutions[0].type | nonprofit |
| authorships[4].institutions[0].lineage | https://openalex.org/I4210094790 |
| authorships[4].institutions[0].country_code | ES |
| authorships[4].institutions[0].display_name | Instituto de Estudios de Ciencias de la Salud de Castilla y León |
| authorships[4].author_position | middle |
| authorships[4].raw_author_name | Marina Toquero-Asensio |
| authorships[4].is_corresponding | False |
| authorships[4].raw_affiliation_strings | National Influenza Centre, Valladolid, Spain; Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León, Soria, Spain. |
| authorships[5].author.id | https://openalex.org/A5101739950 |
| authorships[5].author.orcid | https://orcid.org/0000-0002-9933-9332 |
| authorships[5].author.display_name | Javier Sánchez‐Martínez |
| authorships[5].countries | ES |
| authorships[5].affiliations[0].institution_ids | https://openalex.org/I4210094790 |
| authorships[5].affiliations[0].raw_affiliation_string | National Influenza Centre, Valladolid, Spain; Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León, Soria, Spain. |
| authorships[5].institutions[0].id | https://openalex.org/I4210094790 |
| authorships[5].institutions[0].ror | https://ror.org/00vn23s59 |
| authorships[5].institutions[0].type | nonprofit |
| authorships[5].institutions[0].lineage | https://openalex.org/I4210094790 |
| authorships[5].institutions[0].country_code | ES |
| authorships[5].institutions[0].display_name | Instituto de Estudios de Ciencias de la Salud de Castilla y León |
| authorships[5].author_position | middle |
| authorships[5].raw_author_name | Javier Sánchez-Martínez |
| authorships[5].is_corresponding | False |
| authorships[5].raw_affiliation_strings | National Influenza Centre, Valladolid, Spain; Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León, Soria, Spain. |
| authorships[6].author.id | https://openalex.org/A5094284953 |
| authorships[6].author.orcid | https://orcid.org/0009-0000-1174-6658 |
| authorships[6].author.display_name | Carla Rodríguez-Crespo |
| authorships[6].countries | ES |
| authorships[6].affiliations[0].institution_ids | https://openalex.org/I4210094790 |
| authorships[6].affiliations[0].raw_affiliation_string | National Influenza Centre, Valladolid, Spain; Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León, Soria, Spain. |
| authorships[6].institutions[0].id | https://openalex.org/I4210094790 |
| authorships[6].institutions[0].ror | https://ror.org/00vn23s59 |
| authorships[6].institutions[0].type | nonprofit |
| authorships[6].institutions[0].lineage | https://openalex.org/I4210094790 |
| authorships[6].institutions[0].country_code | ES |
| authorships[6].institutions[0].display_name | Instituto de Estudios de Ciencias de la Salud de Castilla y León |
| authorships[6].author_position | middle |
| authorships[6].raw_author_name | Carla Rodríguez-Crespo |
| authorships[6].is_corresponding | False |
| authorships[6].raw_affiliation_strings | National Influenza Centre, Valladolid, Spain; Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León, Soria, Spain. |
| authorships[7].author.id | https://openalex.org/A5060221828 |
| authorships[7].author.orcid | https://orcid.org/0000-0002-3745-3201 |
| authorships[7].author.display_name | Silvia Rojo‐Rello |
| authorships[7].countries | ES |
| authorships[7].affiliations[0].institution_ids | https://openalex.org/I4210157802 |
| authorships[7].affiliations[0].raw_affiliation_string | National Influenza Centre, Valladolid, Spain; Hospital Clínico Universitario de Valladolid, Valladolid, Spain. |
| authorships[7].institutions[0].id | https://openalex.org/I4210157802 |
| authorships[7].institutions[0].ror | https://ror.org/04fffmj41 |
| authorships[7].institutions[0].type | healthcare |
| authorships[7].institutions[0].lineage | https://openalex.org/I4210157802 |
| authorships[7].institutions[0].country_code | ES |
| authorships[7].institutions[0].display_name | Hospital Clínico Universitario de Valladolid |
| authorships[7].author_position | middle |
| authorships[7].raw_author_name | Silvia Rojo-Rello |
| authorships[7].is_corresponding | False |
| authorships[7].raw_affiliation_strings | National Influenza Centre, Valladolid, Spain; Hospital Clínico Universitario de Valladolid, Valladolid, Spain. |
| authorships[8].author.id | https://openalex.org/A5058994402 |
| authorships[8].author.orcid | https://orcid.org/0000-0001-7957-5656 |
| authorships[8].author.display_name | Marta Domínguez-Gil González |
| authorships[8].countries | ES |
| authorships[8].affiliations[0].institution_ids | https://openalex.org/I4210158107 |
| authorships[8].affiliations[0].raw_affiliation_string | National Influenza Centre, Valladolid, Spain; Hospital Universitario Rio Hortega, Valladolid, Spain. |
| authorships[8].institutions[0].id | https://openalex.org/I4210158107 |
| authorships[8].institutions[0].ror | https://ror.org/05jk45963 |
| authorships[8].institutions[0].type | healthcare |
| authorships[8].institutions[0].lineage | https://openalex.org/I4210158107 |
| authorships[8].institutions[0].country_code | ES |
| authorships[8].institutions[0].display_name | Hospital Universitario Río Hortega |
| authorships[8].author_position | middle |
| authorships[8].raw_author_name | Marta Domínguez-Gil |
| authorships[8].is_corresponding | False |
| authorships[8].raw_affiliation_strings | National Influenza Centre, Valladolid, Spain; Hospital Universitario Rio Hortega, Valladolid, Spain. |
| authorships[9].author.id | https://openalex.org/A5057271005 |
| authorships[9].author.orcid | https://orcid.org/0000-0001-8900-0944 |
| authorships[9].author.display_name | Eduardo Tamayo |
| authorships[9].countries | ES |
| authorships[9].affiliations[0].institution_ids | https://openalex.org/I108103353, https://openalex.org/I4210115082, https://openalex.org/I4210157802 |
| authorships[9].affiliations[0].raw_affiliation_string | Centro de Investigación Biomédica en Red de Enfermedades Infecciosas (CIBERINFEC), Madrid, Spain; Faculty of Medicine, Universidad de Valladolid, Spain; Grupo de Investigación en Biomedicina en Cuidados Críticos, BioCritic, Valladolid, Spain; Hospital Clínico Universitario de Valladolid, Valladolid, Spain. |
| authorships[9].institutions[0].id | https://openalex.org/I4210115082 |
| authorships[9].institutions[0].ror | https://ror.org/02g87qh62 |
| authorships[9].institutions[0].type | facility |
| authorships[9].institutions[0].lineage | https://openalex.org/I2801357902, https://openalex.org/I4210115082, https://openalex.org/I4387152914 |
| authorships[9].institutions[0].country_code | ES |
| authorships[9].institutions[0].display_name | Centro de Investigación Biomédica en Red |
| authorships[9].institutions[1].id | https://openalex.org/I4210157802 |
| authorships[9].institutions[1].ror | https://ror.org/04fffmj41 |
| authorships[9].institutions[1].type | healthcare |
| authorships[9].institutions[1].lineage | https://openalex.org/I4210157802 |
| authorships[9].institutions[1].country_code | ES |
| authorships[9].institutions[1].display_name | Hospital Clínico Universitario de Valladolid |
| authorships[9].institutions[2].id | https://openalex.org/I108103353 |
| authorships[9].institutions[2].ror | https://ror.org/01fvbaw18 |
| authorships[9].institutions[2].type | education |
| authorships[9].institutions[2].lineage | https://openalex.org/I108103353 |
| authorships[9].institutions[2].country_code | ES |
| authorships[9].institutions[2].display_name | Universidad de Valladolid |
| authorships[9].author_position | middle |
| authorships[9].raw_author_name | Eduardo Tamayo-Gómez |
| authorships[9].is_corresponding | False |
| authorships[9].raw_affiliation_strings | Centro de Investigación Biomédica en Red de Enfermedades Infecciosas (CIBERINFEC), Madrid, Spain; Faculty of Medicine, Universidad de Valladolid, Spain; Grupo de Investigación en Biomedicina en Cuidados Críticos, BioCritic, Valladolid, Spain; Hospital Clínico Universitario de Valladolid, Valladolid, Spain. |
| authorships[10].author.id | https://openalex.org/A5025062034 |
| authorships[10].author.orcid | |
| authorships[10].author.display_name | Marier Hernández‐Pérez |
| authorships[10].countries | ES |
| authorships[10].affiliations[0].institution_ids | https://openalex.org/I108103353 |
| authorships[10].affiliations[0].raw_affiliation_string | National Influenza Centre, Valladolid, Spain; Faculty of Medicine, Universidad de Valladolid, Spain. |
| authorships[10].institutions[0].id | https://openalex.org/I108103353 |
| authorships[10].institutions[0].ror | https://ror.org/01fvbaw18 |
| authorships[10].institutions[0].type | education |
| authorships[10].institutions[0].lineage | https://openalex.org/I108103353 |
| authorships[10].institutions[0].country_code | ES |
| authorships[10].institutions[0].display_name | Universidad de Valladolid |
| authorships[10].author_position | middle |
| authorships[10].raw_author_name | Marta Hernández-Pérez |
| authorships[10].is_corresponding | False |
| authorships[10].raw_affiliation_strings | National Influenza Centre, Valladolid, Spain; Faculty of Medicine, Universidad de Valladolid, Spain. |
| authorships[11].author.id | https://openalex.org/A5084266011 |
| authorships[11].author.orcid | https://orcid.org/0000-0002-5357-6340 |
| authorships[11].author.display_name | José María Eirós Bouza |
| authorships[11].countries | ES |
| authorships[11].affiliations[0].institution_ids | https://openalex.org/I108103353, https://openalex.org/I4210115082, https://openalex.org/I4210157802, https://openalex.org/I4210158107 |
| authorships[11].affiliations[0].raw_affiliation_string | National Influenza Centre, Valladolid, Spain; Centro de Investigación Biomédica en Red de Enfermedades Infecciosas (CIBERINFEC), Madrid, Spain; Faculty of Medicine, Universidad de Valladolid, Spain; Hospital Clínico Universitario de Valladolid, Valladolid, Spain; Hospital Universitario Rio Hortega, Valladolid, Spain. |
| authorships[11].institutions[0].id | https://openalex.org/I4210115082 |
| authorships[11].institutions[0].ror | https://ror.org/02g87qh62 |
| authorships[11].institutions[0].type | facility |
| authorships[11].institutions[0].lineage | https://openalex.org/I2801357902, https://openalex.org/I4210115082, https://openalex.org/I4387152914 |
| authorships[11].institutions[0].country_code | ES |
| authorships[11].institutions[0].display_name | Centro de Investigación Biomédica en Red |
| authorships[11].institutions[1].id | https://openalex.org/I4210157802 |
| authorships[11].institutions[1].ror | https://ror.org/04fffmj41 |
| authorships[11].institutions[1].type | healthcare |
| authorships[11].institutions[1].lineage | https://openalex.org/I4210157802 |
| authorships[11].institutions[1].country_code | ES |
| authorships[11].institutions[1].display_name | Hospital Clínico Universitario de Valladolid |
| authorships[11].institutions[2].id | https://openalex.org/I4210158107 |
| authorships[11].institutions[2].ror | https://ror.org/05jk45963 |
| authorships[11].institutions[2].type | healthcare |
| authorships[11].institutions[2].lineage | https://openalex.org/I4210158107 |
| authorships[11].institutions[2].country_code | ES |
| authorships[11].institutions[2].display_name | Hospital Universitario Río Hortega |
| authorships[11].institutions[3].id | https://openalex.org/I108103353 |
| authorships[11].institutions[3].ror | https://ror.org/01fvbaw18 |
| authorships[11].institutions[3].type | education |
| authorships[11].institutions[3].lineage | https://openalex.org/I108103353 |
| authorships[11].institutions[3].country_code | ES |
| authorships[11].institutions[3].display_name | Universidad de Valladolid |
| authorships[11].author_position | last |
| authorships[11].raw_author_name | José M Eiros |
| authorships[11].is_corresponding | False |
| authorships[11].raw_affiliation_strings | National Influenza Centre, Valladolid, Spain; Centro de Investigación Biomédica en Red de Enfermedades Infecciosas (CIBERINFEC), Madrid, Spain; Faculty of Medicine, Universidad de Valladolid, Spain; Hospital Clínico Universitario de Valladolid, Valladolid, Spain; Hospital Universitario Rio Hortega, Valladolid, Spain. |
| has_content.pdf | False |
| has_content.grobid_xml | False |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://doi.org/10.1016/j.virusres.2025.199599 |
| open_access.oa_status | gold |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | A 15-year study of neuraminidase mutations and the increasing of S247N mutation in Spain |
| has_fulltext | False |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T10167 |
| primary_topic.field.id | https://openalex.org/fields/27 |
| primary_topic.field.display_name | Medicine |
| primary_topic.score | 0.9975000023841858 |
| primary_topic.domain.id | https://openalex.org/domains/4 |
| primary_topic.domain.display_name | Health Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/2713 |
| primary_topic.subfield.display_name | Epidemiology |
| primary_topic.display_name | Influenza Virus Research Studies |
| related_works | https://openalex.org/W4391375266, https://openalex.org/W2082860237, https://openalex.org/W2119695867, https://openalex.org/W2130076355, https://openalex.org/W1990804418, https://openalex.org/W1993764875, https://openalex.org/W2046158694, https://openalex.org/W2788277189, https://openalex.org/W2146849562, https://openalex.org/W2028961943 |
| cited_by_count | 0 |
| locations_count | 4 |
| best_oa_location.id | doi:10.1016/j.virusres.2025.199599 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S114911520 |
| best_oa_location.source.issn | 0168-1702, 1872-7492 |
| best_oa_location.source.type | journal |
| best_oa_location.source.is_oa | True |
| best_oa_location.source.issn_l | 0168-1702 |
| best_oa_location.source.is_core | True |
| best_oa_location.source.is_in_doaj | True |
| best_oa_location.source.display_name | Virus Research |
| best_oa_location.source.host_organization | https://openalex.org/P4310320990 |
| best_oa_location.source.host_organization_name | Elsevier BV |
| best_oa_location.source.host_organization_lineage | https://openalex.org/P4310320990 |
| best_oa_location.license | cc-by-nc-nd |
| best_oa_location.pdf_url | |
| best_oa_location.version | publishedVersion |
| best_oa_location.raw_type | journal-article |
| best_oa_location.license_id | https://openalex.org/licenses/cc-by-nc-nd |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | True |
| best_oa_location.raw_source_name | Virus Research |
| best_oa_location.landing_page_url | https://doi.org/10.1016/j.virusres.2025.199599 |
| primary_location.id | doi:10.1016/j.virusres.2025.199599 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S114911520 |
| primary_location.source.issn | 0168-1702, 1872-7492 |
| primary_location.source.type | journal |
| primary_location.source.is_oa | True |
| primary_location.source.issn_l | 0168-1702 |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | True |
| primary_location.source.display_name | Virus Research |
| primary_location.source.host_organization | https://openalex.org/P4310320990 |
| primary_location.source.host_organization_name | Elsevier BV |
| primary_location.source.host_organization_lineage | https://openalex.org/P4310320990 |
| primary_location.license | cc-by-nc-nd |
| primary_location.pdf_url | |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | https://openalex.org/licenses/cc-by-nc-nd |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | Virus Research |
| primary_location.landing_page_url | https://doi.org/10.1016/j.virusres.2025.199599 |
| publication_date | 2025-06-26 |
| publication_year | 2025 |
| referenced_works | https://openalex.org/W2923897892, https://openalex.org/W2905326836, https://openalex.org/W2063704000, https://openalex.org/W4400535497, https://openalex.org/W2120846782, https://openalex.org/W2164343098, https://openalex.org/W2799702858, https://openalex.org/W1968256827, https://openalex.org/W134199829, https://openalex.org/W3006274289, https://openalex.org/W2110877864, https://openalex.org/W4392794207, https://openalex.org/W2159616563, https://openalex.org/W2897317761, https://openalex.org/W2086932516, https://openalex.org/W4399570266, https://openalex.org/W2809529263, https://openalex.org/W4306152119, https://openalex.org/W4404276841, https://openalex.org/W2122030378, https://openalex.org/W2409649694, https://openalex.org/W4220814471, https://openalex.org/W3003957783, https://openalex.org/W2038433223, https://openalex.org/W3202979556, https://openalex.org/W2041128110, https://openalex.org/W2158645259, https://openalex.org/W4321239598, https://openalex.org/W2121948202, https://openalex.org/W1976220879, https://openalex.org/W2082647108, https://openalex.org/W41880533, https://openalex.org/W2128060816 |
| referenced_works_count | 33 |
| abstract_inverted_index.a | 51, 117, 144, 169, 199 |
| abstract_inverted_index.%. | 96 |
| abstract_inverted_index.15 | 35, 90 |
| abstract_inverted_index.44 | 147 |
| abstract_inverted_index.70 | 108 |
| abstract_inverted_index.NA | 32, 61, 79 |
| abstract_inverted_index.To | 39 |
| abstract_inverted_index.be | 198 |
| abstract_inverted_index.do | 40 |
| abstract_inverted_index.in | 19, 37, 84, 103, 120, 140, 156, 172 |
| abstract_inverted_index.is | 5, 194 |
| abstract_inverted_index.it | 182 |
| abstract_inverted_index.of | 16, 31, 53, 78, 98, 123, 130, 133, 146 |
| abstract_inverted_index.to | 13, 27, 184, 190 |
| abstract_inverted_index.we | 42, 49 |
| abstract_inverted_index.%), | 109 |
| abstract_inverted_index.Our | 72 |
| abstract_inverted_index.The | 0, 128 |
| abstract_inverted_index.and | 8, 59, 64, 180, 196 |
| abstract_inverted_index.but | 139 |
| abstract_inverted_index.due | 12 |
| abstract_inverted_index.for | 201 |
| abstract_inverted_index.its | 192 |
| abstract_inverted_index.so, | 41 |
| abstract_inverted_index.the | 14, 20, 29, 44, 66, 76, 85, 89, 99, 104, 112, 121, 141, 157, 176 |
| abstract_inverted_index.two | 161, 178 |
| abstract_inverted_index.was | 101, 126, 137 |
| abstract_inverted_index.(NA) | 22 |
| abstract_inverted_index.2022 | 136 |
| abstract_inverted_index.Most | 97 |
| abstract_inverted_index.Some | 165 |
| abstract_inverted_index.This | 24 |
| abstract_inverted_index.four | 86 |
| abstract_inverted_index.from | 47, 111 |
| abstract_inverted_index.have | 167 |
| abstract_inverted_index.only | 160, 186 |
| abstract_inverted_index.over | 34, 175 |
| abstract_inverted_index.past | 177 |
| abstract_inverted_index.that | 75 |
| abstract_inverted_index.this | 131, 173 |
| abstract_inverted_index.type | 132 |
| abstract_inverted_index.used | 43 |
| abstract_inverted_index.were | 153, 163 |
| abstract_inverted_index.when | 116 |
| abstract_inverted_index.0.5-5 | 95 |
| abstract_inverted_index.S247N | 124, 151 |
| abstract_inverted_index.aimed | 26 |
| abstract_inverted_index.being | 93 |
| abstract_inverted_index.cases | 162 |
| abstract_inverted_index.found | 102 |
| abstract_inverted_index.gene. | 23 |
| abstract_inverted_index.often | 10 |
| abstract_inverted_index.other | 158 |
| abstract_inverted_index.rare, | 138 |
| abstract_inverted_index.study | 25 |
| abstract_inverted_index.their | 203 |
| abstract_inverted_index.total | 52, 145 |
| abstract_inverted_index.using | 69 |
| abstract_inverted_index.virus | 62 |
| abstract_inverted_index.which | 48 |
| abstract_inverted_index.while | 155 |
| abstract_inverted_index.years | 36 |
| abstract_inverted_index.11,125 | 54 |
| abstract_inverted_index.GISAID | 45 |
| abstract_inverted_index.Spain. | 38 |
| abstract_inverted_index.arises | 11 |
| abstract_inverted_index.around | 94 |
| abstract_inverted_index.before | 135 |
| abstract_inverted_index.confer | 185 |
| abstract_inverted_index.during | 88 |
| abstract_inverted_index.reason | 200 |
| abstract_inverted_index.season | 114, 143 |
| abstract_inverted_index.should | 197 |
| abstract_inverted_index.showed | 74 |
| abstract_inverted_index.years, | 159 |
| abstract_inverted_index.(around | 107 |
| abstract_inverted_index.against | 3 |
| abstract_inverted_index.appears | 183 |
| abstract_inverted_index.arsenal | 2 |
| abstract_inverted_index.limited | 7 |
| abstract_inverted_index.reduced | 188 |
| abstract_inverted_index.results | 73 |
| abstract_inverted_index.seasons | 91, 179 |
| abstract_inverted_index.studies | 166 |
| abstract_inverted_index.subtype | 106 |
| abstract_inverted_index.viruses | 87, 149 |
| abstract_inverted_index.A(H3N2), | 57 |
| abstract_inverted_index.although | 181 |
| abstract_inverted_index.analyzed | 65 |
| abstract_inverted_index.constant | 83 |
| abstract_inverted_index.database | 46 |
| abstract_inverted_index.evaluate | 28 |
| abstract_inverted_index.increase | 119, 171, 193 |
| abstract_inverted_index.mutation | 125, 134, 174 |
| abstract_inverted_index.onwards, | 115 |
| abstract_inverted_index.remained | 82 |
| abstract_inverted_index.slightly | 187 |
| abstract_inverted_index.2023-2024 | 113, 142 |
| abstract_inverted_index.FluSurver | 70 |
| abstract_inverted_index.described | 168 |
| abstract_inverted_index.detected, | 154 |
| abstract_inverted_index.emergence | 15 |
| abstract_inverted_index.evolution | 30 |
| abstract_inverted_index.extremely | 6 |
| abstract_inverted_index.harboring | 150 |
| abstract_inverted_index.increased | 202 |
| abstract_inverted_index.influenza | 4, 55, 148 |
| abstract_inverted_index.mutations | 33, 68, 81, 152 |
| abstract_inverted_index.observed. | 127, 164 |
| abstract_inverted_index.software. | 71 |
| abstract_inverted_index.B/Victoria | 58 |
| abstract_inverted_index.B/Yamagata | 60 |
| abstract_inverted_index.downloaded | 50 |
| abstract_inverted_index.especially | 18, 110 |
| abstract_inverted_index.evaluated, | 92 |
| abstract_inverted_index.inhibition | 189 |
| abstract_inverted_index.mutations, | 17 |
| abstract_inverted_index.noteworthy | 195 |
| abstract_inverted_index.occurrence | 77, 122, 129 |
| abstract_inverted_index.resistance | 9, 67, 80, 100 |
| abstract_inverted_index.sequences, | 63 |
| abstract_inverted_index.vigilance. | 204 |
| abstract_inverted_index.significant | 118, 170 |
| abstract_inverted_index.therapeutic | 1 |
| abstract_inverted_index.A(H1N1)pdm09 | 105 |
| abstract_inverted_index.oseltamivir, | 191 |
| abstract_inverted_index.A(H1N1)pdm09, | 56 |
| abstract_inverted_index.neuraminidase | 21 |
| cited_by_percentile_year | |
| countries_distinct_count | 1 |
| institutions_distinct_count | 12 |
| citation_normalized_percentile.value | 0.33868456 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |