A case of interstitial lung disease with alveolar hemorrhage induced by pembrolizumab Article Swipe
Teppei Sugano
,
Masahiro Seike
,
Rintaro Noro
,
S. Kaburaki
,
Takehiro Tozuka
,
Akihiko Takahashi
,
Natsuki Takano
,
Toru Tanaka
,
Takeru Kashiwada
,
Susumu Takeuchi
,
Yuji Minegishi
,
Yoshinobu Saito
,
Kaoru Kubota
,
Yasuhiro Terasaki
,
Akihiko Gemma
·
YOU?
·
· 2018
· Open Access
·
· DOI: https://doi.org/10.2147/ott.s169321
YOU?
·
· 2018
· Open Access
·
· DOI: https://doi.org/10.2147/ott.s169321
We herein describe the case of a 67-year-old woman with advanced lung adenocarcinoma who developed interstitial lung disease (ILD) with alveolar hemorrhage induced by pembrolizumab. She received four courses of pembrolizumab therapy and achieved a partial response. She had no respiratory symptoms; however, chest radiography and computed tomography (CT) revealed ground-glass opacities (GGOs) and crazy-paving pattern. Based on findings of bloody bronchoalveolar lavage fluid and transbronchial lung biopsy samples, pembrolizumab-induced ILD with alveolar hemorrhage was diagnosed. Corticosteroid therapy rapidly improved alveolar hemorrhage and regressed GGOs on CT scan. This is the first report on ILD with alveolar hemorrhage induced by pembrolizumab.
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- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.2147/ott.s169321
- https://www.dovepress.com/front_end/cr_data/cache/pdf/download_1613391688_602a6748f044d/ott-169321-a-case-of-interstitial-lung-disease-with-alveolar-hemorrhage-091418.pdf
- OA Status
- gold
- Cited By
- 10
- References
- 13
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W2892123356
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W2892123356Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.2147/ott.s169321Digital Object Identifier
- Title
-
A case of interstitial lung disease with alveolar hemorrhage induced by pembrolizumabWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2018Year of publication
- Publication date
-
2018-09-01Full publication date if available
- Authors
-
Teppei Sugano, Masahiro Seike, Rintaro Noro, S. Kaburaki, Takehiro Tozuka, Akihiko Takahashi, Natsuki Takano, Toru Tanaka, Takeru Kashiwada, Susumu Takeuchi, Yuji Minegishi, Yoshinobu Saito, Kaoru Kubota, Yasuhiro Terasaki, Akihiko GemmaList of authors in order
- Landing page
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https://doi.org/10.2147/ott.s169321Publisher landing page
- PDF URL
-
https://www.dovepress.com/front_end/cr_data/cache/pdf/download_1613391688_602a6748f044d/ott-169321-a-case-of-interstitial-lung-disease-with-alveolar-hemorrhage-091418.pdfDirect link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
-
https://www.dovepress.com/front_end/cr_data/cache/pdf/download_1613391688_602a6748f044d/ott-169321-a-case-of-interstitial-lung-disease-with-alveolar-hemorrhage-091418.pdfDirect OA link when available
- Concepts
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Pembrolizumab, Interstitial lung disease, Medicine, Lung, Disease, Pathology, Lung cancer, Internal medicine, Cancer, ImmunotherapyTop concepts (fields/topics) attached by OpenAlex
- Cited by
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10Total citation count in OpenAlex
- Citations by year (recent)
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2023: 1, 2022: 1, 2021: 4, 2020: 2, 2019: 2Per-year citation counts (last 5 years)
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13Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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