A case report of clubbing as the initial sign of systemic sclerosis sine scleroderma: A rare possible presentation Article Swipe
Anahita Amirpour
,
Parastoo Ghorbani
,
Erfan Ghadirzadeh
,
Elham Charkazi
,
Elham Paraandavaji
·
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.1002/ccr3.8090
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.1002/ccr3.8090
Key Clinical Message Even in the absence of characteristic cutaneous symptoms of scleroderma, systemic sclerosis should be considered in the differential diagnosis of patients initially diagnosed with idiopathic interstitial lung disease. Abstract Systemic sclerosis (SSc) is an idiopathic connective tissue disorder characterized by multisystem involvement. Although skin thickening is a hallmark manifestation of SSc, a subset known as systemic sclerosis sine scleroderma (ssSSc) presents with internal organ involvement and positive serologic markers in the absence of significant cutaneous manifestations. We report the case of a 36‐year‐old Iranian woman who presented with clubbing as an initial symptom of ssSSc. Notably, clubbing as the sole initial sign of the disease has not been previously reported. Timely diagnosis of ssSSc is crucial to facilitate appropriate treatment and prevent disease progression. Physicians should adopt a comprehensive approach when evaluating patients presenting with limited clinical features, as they might be indicative of underlying ssSSc.
Related Topics
Concepts
Medicine
Scleroderma (fungus)
Differential diagnosis
Interstitial lung disease
Dermatology
Disease
Connective tissue disease
Undifferentiated connective tissue disease
Systemic scleroderma
Pathology
Systemic disease
Rare disease
Lung
Autoimmune disease
Internal medicine
Inoculation
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1002/ccr3.8090
- https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ccr3.8090
- OA Status
- gold
- Cited By
- 2
- References
- 16
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4387818353
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4387818353Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1002/ccr3.8090Digital Object Identifier
- Title
-
A case report of clubbing as the initial sign of systemic sclerosis sine scleroderma: A rare possible presentationWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2023Year of publication
- Publication date
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2023-10-01Full publication date if available
- Authors
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Anahita Amirpour, Parastoo Ghorbani, Erfan Ghadirzadeh, Elham Charkazi, Elham ParaandavajiList of authors in order
- Landing page
-
https://doi.org/10.1002/ccr3.8090Publisher landing page
- PDF URL
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https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ccr3.8090Direct link to full text PDF
- Open access
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YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
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https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ccr3.8090Direct OA link when available
- Concepts
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Medicine, Scleroderma (fungus), Differential diagnosis, Interstitial lung disease, Dermatology, Disease, Connective tissue disease, Undifferentiated connective tissue disease, Systemic scleroderma, Pathology, Systemic disease, Rare disease, Lung, Autoimmune disease, Internal medicine, InoculationTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
2Total citation count in OpenAlex
- Citations by year (recent)
-
2024: 1, 2023: 1Per-year citation counts (last 5 years)
- References (count)
-
16Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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