A Damage-Independent Role for 53BP1 that Impacts Break Order and Igh Architecture during Class Switch Recombination Article Swipe

PDF

Pedro P. Rocha , Ramya Raviram , Yi Fu , Jung‐Hyun Kim , Vincent Luo , Arafat Aljoufi , Emily Swanzey , Alessandra Pasquarella , Alessia Balestrini , Emily R. Miraldi , Richard Bonneau , John H.J. Petrini , Gunnar Schotta , Jane A. Skok ·

YOU? · · 2016 · Open Access · · DOI: https://doi.org/10.1016/j.celrep.2016.05.073

Related Topics

Immunoglobulin Class Switching

Concepts

Immunoglobulin class switching Chromatin Biology Cell biology Recombination Isotype DNA Exon Genetics Molecular biology Gene B cell Antibody Monoclonal antibody

Metadata

Type: article
Language: en
Landing Page: https://doi.org/10.1016/j.celrep.2016.05.073
PDF: http://www.cell.com/article/S2211124716306866/pdf
OA Status: gold
Cited By: 36
References: 41
Related Works: 10
OpenAlex ID: https://openalex.org/W2437539949

All OpenAlex metadata

Raw OpenAlex JSON

OpenAlex ID: https://openalex.org/W2437539949

Canonical identifier for this work in OpenAlex
DOI: https://doi.org/10.1016/j.celrep.2016.05.073

Digital Object Identifier
Title: A Damage-Independent Role for 53BP1 that Impacts Break Order and Igh Architecture during Class Switch Recombination

Work title
Type: article

OpenAlex work type
Language: en

Primary language
Publication year: 2016

Year of publication
Publication date: 2016-06-01

Full publication date if available
Authors: Pedro P. Rocha, Ramya Raviram, Yi Fu, Jung‐Hyun Kim, Vincent Luo, Arafat Aljoufi, Emily Swanzey, Alessandra Pasquarella, Alessia Balestrini, Emily R. Miraldi, Richard Bonneau, John H.J. Petrini, Gunnar Schotta, Jane A. Skok

List of authors in order
Landing page: https://doi.org/10.1016/j.celrep.2016.05.073

Publisher landing page
PDF URL: https://www.cell.com/article/S2211124716306866/pdf

Direct link to full text PDF
Open access: Yes

Whether a free full text is available
OA status: gold

Open access status per OpenAlex
OA URL: https://www.cell.com/article/S2211124716306866/pdf

Direct OA link when available
Concepts: Immunoglobulin class switching, Chromatin, Biology, Cell biology, Recombination, Isotype, DNA, Exon, Genetics, Molecular biology, Gene, B cell, Antibody, Monoclonal antibody

Top concepts (fields/topics) attached by OpenAlex
Cited by: 36

Total citation count in OpenAlex
Citations by year (recent): 2025: 2, 2024: 4, 2023: 2, 2022: 4, 2021: 2

Per-year citation counts (last 5 years)
References (count): 41

Number of works referenced by this work
Related works (count): 10

Other works algorithmically related by OpenAlex

Full payload

id	https://openalex.org/W2437539949
doi	https://doi.org/10.1016/j.celrep.2016.05.073
ids.doi	https://doi.org/10.1016/j.celrep.2016.05.073
ids.mag	2437539949
ids.pmid	https://pubmed.ncbi.nlm.nih.gov/27320916
ids.openalex	https://openalex.org/W2437539949
fwci	2.94654481
mesh[0].qualifier_ui
mesh[0].descriptor_ui	D000818
mesh[0].is_major_topic	False
mesh[0].qualifier_name
mesh[0].descriptor_name	Animals
mesh[1].qualifier_ui
mesh[1].descriptor_ui	D001483
mesh[1].is_major_topic	False
mesh[1].qualifier_name
mesh[1].descriptor_name	Base Sequence
mesh[2].qualifier_ui	Q000378
mesh[2].descriptor_ui	D002843
mesh[2].is_major_topic	False
mesh[2].qualifier_name	metabolism
mesh[2].descriptor_name	Chromatin
mesh[3].qualifier_ui
mesh[3].descriptor_ui	D053903
mesh[3].is_major_topic	True
mesh[3].qualifier_name
mesh[3].descriptor_name	DNA Breaks, Double-Stranded
mesh[4].qualifier_ui	Q000235
mesh[4].descriptor_ui	D017578
mesh[4].is_major_topic	False
mesh[4].qualifier_name	genetics
mesh[4].descriptor_name	Immunoglobulin Class Switching
mesh[5].qualifier_ui	Q000235
mesh[5].descriptor_ui	D007143
mesh[5].is_major_topic	False
mesh[5].qualifier_name	genetics
mesh[5].descriptor_name	Immunoglobulin Heavy Chains
mesh[6].qualifier_ui
mesh[6].descriptor_ui	D051379
mesh[6].is_major_topic	False
mesh[6].qualifier_name
mesh[6].descriptor_name	Mice
mesh[7].qualifier_ui
mesh[7].descriptor_ui	D011485
mesh[7].is_major_topic	False
mesh[7].qualifier_name
mesh[7].descriptor_name	Protein Binding
mesh[8].qualifier_ui
mesh[8].descriptor_ui	D011995
mesh[8].is_major_topic	True
mesh[8].qualifier_name
mesh[8].descriptor_name	Recombination, Genetic
mesh[9].qualifier_ui
mesh[9].descriptor_ui	D059010
mesh[9].is_major_topic	False
mesh[9].qualifier_name
mesh[9].descriptor_name	Single-Cell Analysis
mesh[10].qualifier_ui	Q000378
mesh[10].descriptor_ui	D000071857
mesh[10].is_major_topic	False
mesh[10].qualifier_name	metabolism
mesh[10].descriptor_name	Tumor Suppressor p53-Binding Protein 1
mesh[11].qualifier_ui
mesh[11].descriptor_ui	D000818
mesh[11].is_major_topic	False
mesh[11].qualifier_name
mesh[11].descriptor_name	Animals
mesh[12].qualifier_ui
mesh[12].descriptor_ui	D001483
mesh[12].is_major_topic	False
mesh[12].qualifier_name
mesh[12].descriptor_name	Base Sequence
mesh[13].qualifier_ui	Q000378
mesh[13].descriptor_ui	D002843
mesh[13].is_major_topic	False
mesh[13].qualifier_name	metabolism
mesh[13].descriptor_name	Chromatin
mesh[14].qualifier_ui
mesh[14].descriptor_ui	D053903
mesh[14].is_major_topic	True
mesh[14].qualifier_name
mesh[14].descriptor_name	DNA Breaks, Double-Stranded
mesh[15].qualifier_ui	Q000235
mesh[15].descriptor_ui	D017578
mesh[15].is_major_topic	False
mesh[15].qualifier_name	genetics
mesh[15].descriptor_name	Immunoglobulin Class Switching
mesh[16].qualifier_ui	Q000235
mesh[16].descriptor_ui	D007143
mesh[16].is_major_topic	False
mesh[16].qualifier_name	genetics
mesh[16].descriptor_name	Immunoglobulin Heavy Chains
mesh[17].qualifier_ui
mesh[17].descriptor_ui	D051379
mesh[17].is_major_topic	False
mesh[17].qualifier_name
mesh[17].descriptor_name	Mice
mesh[18].qualifier_ui
mesh[18].descriptor_ui	D011485
mesh[18].is_major_topic	False
mesh[18].qualifier_name
mesh[18].descriptor_name	Protein Binding
mesh[19].qualifier_ui
mesh[19].descriptor_ui	D011995
mesh[19].is_major_topic	True
mesh[19].qualifier_name
mesh[19].descriptor_name	Recombination, Genetic
mesh[20].qualifier_ui
mesh[20].descriptor_ui	D059010
mesh[20].is_major_topic	False
mesh[20].qualifier_name
mesh[20].descriptor_name	Single-Cell Analysis
mesh[21].qualifier_ui	Q000378
mesh[21].descriptor_ui	D000071857
mesh[21].is_major_topic	False
mesh[21].qualifier_name	metabolism
mesh[21].descriptor_name	Tumor Suppressor p53-Binding Protein 1
type	article
title	A Damage-Independent Role for 53BP1 that Impacts Break Order and Igh Architecture during Class Switch Recombination
biblio.issue	1
biblio.volume	16
biblio.last_page	55
biblio.first_page	48
topics[0].id	https://openalex.org/T10123
topics[0].field.id	https://openalex.org/fields/13
topics[0].field.display_name	Biochemistry, Genetics and Molecular Biology
topics[0].score	0.9991999864578247
topics[0].domain.id	https://openalex.org/domains/1
topics[0].domain.display_name	Life Sciences
topics[0].subfield.id	https://openalex.org/subfields/1312
topics[0].subfield.display_name	Molecular Biology
topics[0].display_name	DNA Repair Mechanisms
topics[1].id	https://openalex.org/T10031
topics[1].field.id	https://openalex.org/fields/24
topics[1].field.display_name	Immunology and Microbiology
topics[1].score	0.9987999796867371
topics[1].domain.id	https://openalex.org/domains/1
topics[1].domain.display_name	Life Sciences
topics[1].subfield.id	https://openalex.org/subfields/2403
topics[1].subfield.display_name	Immunology
topics[1].display_name	T-cell and B-cell Immunology
topics[2].id	https://openalex.org/T10497
topics[2].field.id	https://openalex.org/fields/13
topics[2].field.display_name	Biochemistry, Genetics and Molecular Biology
topics[2].score	0.989799976348877
topics[2].domain.id	https://openalex.org/domains/1
topics[2].domain.display_name	Life Sciences
topics[2].subfield.id	https://openalex.org/subfields/1312
topics[2].subfield.display_name	Molecular Biology
topics[2].display_name	Fungal and yeast genetics research
funders[0].id	https://openalex.org/F4320332161
funders[0].ror	https://ror.org/01cwqze88
funders[0].display_name	National Institutes of Health
is_xpac	False
apc_list.value	5200
apc_list.currency	USD
apc_list.value_usd	5200
apc_paid.value	5200
apc_paid.currency	USD
apc_paid.value_usd	5200
concepts[0].id	https://openalex.org/C137756551
concepts[0].level	4
concepts[0].score	0.8408052921295166
concepts[0].wikidata	https://www.wikidata.org/wiki/Q2386881
concepts[0].display_name	Immunoglobulin class switching
concepts[1].id	https://openalex.org/C83640560
concepts[1].level	3
concepts[1].score	0.7681260108947754
concepts[1].wikidata	https://www.wikidata.org/wiki/Q180951
concepts[1].display_name	Chromatin
concepts[2].id	https://openalex.org/C86803240
concepts[2].level	0
concepts[2].score	0.4913603365421295
concepts[2].wikidata	https://www.wikidata.org/wiki/Q420
concepts[2].display_name	Biology
concepts[3].id	https://openalex.org/C95444343
concepts[3].level	1
concepts[3].score	0.4845241904258728
concepts[3].wikidata	https://www.wikidata.org/wiki/Q7141
concepts[3].display_name	Cell biology
concepts[4].id	https://openalex.org/C156695909
concepts[4].level	3
concepts[4].score	0.46384623646736145
concepts[4].wikidata	https://www.wikidata.org/wiki/Q3373825
concepts[4].display_name	Recombination
concepts[5].id	https://openalex.org/C2777991845
concepts[5].level	4
concepts[5].score	0.4360863268375397
concepts[5].wikidata	https://www.wikidata.org/wiki/Q2396793
concepts[5].display_name	Isotype
concepts[6].id	https://openalex.org/C552990157
concepts[6].level	2
concepts[6].score	0.425489604473114
concepts[6].wikidata	https://www.wikidata.org/wiki/Q7430
concepts[6].display_name	DNA
concepts[7].id	https://openalex.org/C36823959
concepts[7].level	3
concepts[7].score	0.41535037755966187
concepts[7].wikidata	https://www.wikidata.org/wiki/Q373027
concepts[7].display_name	Exon
concepts[8].id	https://openalex.org/C54355233
concepts[8].level	1
concepts[8].score	0.40859174728393555
concepts[8].wikidata	https://www.wikidata.org/wiki/Q7162
concepts[8].display_name	Genetics
concepts[9].id	https://openalex.org/C153911025
concepts[9].level	1
concepts[9].score	0.3885473310947418
concepts[9].wikidata	https://www.wikidata.org/wiki/Q7202
concepts[9].display_name	Molecular biology
concepts[10].id	https://openalex.org/C104317684
concepts[10].level	2
concepts[10].score	0.2775234580039978
concepts[10].wikidata	https://www.wikidata.org/wiki/Q7187
concepts[10].display_name	Gene
concepts[11].id	https://openalex.org/C2778453870
concepts[11].level	3
concepts[11].score	0.21367791295051575
concepts[11].wikidata	https://www.wikidata.org/wiki/Q188930
concepts[11].display_name	B cell
concepts[12].id	https://openalex.org/C159654299
concepts[12].level	2
concepts[12].score	0.19313669204711914
concepts[12].wikidata	https://www.wikidata.org/wiki/Q79460
concepts[12].display_name	Antibody
concepts[13].id	https://openalex.org/C542903549
concepts[13].level	3
concepts[13].score	0.0
concepts[13].wikidata	https://www.wikidata.org/wiki/Q422248
concepts[13].display_name	Monoclonal antibody
keywords[0].id	https://openalex.org/keywords/immunoglobulin-class-switching
keywords[0].score	0.8408052921295166
keywords[0].display_name	Immunoglobulin class switching
keywords[1].id	https://openalex.org/keywords/chromatin
keywords[1].score	0.7681260108947754
keywords[1].display_name	Chromatin
keywords[2].id	https://openalex.org/keywords/biology
keywords[2].score	0.4913603365421295
keywords[2].display_name	Biology
keywords[3].id	https://openalex.org/keywords/cell-biology
keywords[3].score	0.4845241904258728
keywords[3].display_name	Cell biology
keywords[4].id	https://openalex.org/keywords/recombination
keywords[4].score	0.46384623646736145
keywords[4].display_name	Recombination
keywords[5].id	https://openalex.org/keywords/isotype
keywords[5].score	0.4360863268375397
keywords[5].display_name	Isotype
keywords[6].id	https://openalex.org/keywords/dna
keywords[6].score	0.425489604473114
keywords[6].display_name	DNA
keywords[7].id	https://openalex.org/keywords/exon
keywords[7].score	0.41535037755966187
keywords[7].display_name	Exon
keywords[8].id	https://openalex.org/keywords/genetics
keywords[8].score	0.40859174728393555
keywords[8].display_name	Genetics
keywords[9].id	https://openalex.org/keywords/molecular-biology
keywords[9].score	0.3885473310947418
keywords[9].display_name	Molecular biology
keywords[10].id	https://openalex.org/keywords/gene
keywords[10].score	0.2775234580039978
keywords[10].display_name	Gene
keywords[11].id	https://openalex.org/keywords/b-cell
keywords[11].score	0.21367791295051575
keywords[11].display_name	B cell
keywords[12].id	https://openalex.org/keywords/antibody
keywords[12].score	0.19313669204711914
keywords[12].display_name	Antibody
language	en
locations[0].id	doi:10.1016/j.celrep.2016.05.073
locations[0].is_oa	True
locations[0].source.id	https://openalex.org/S169236886
locations[0].source.issn	2211-1247, 2639-1856
locations[0].source.type	journal
locations[0].source.is_oa	True
locations[0].source.issn_l	2211-1247
locations[0].source.is_core	True
locations[0].source.is_in_doaj	True
locations[0].source.display_name	Cell Reports
locations[0].source.host_organization	https://openalex.org/P4310315673
locations[0].source.host_organization_name	Cell Press
locations[0].source.host_organization_lineage	https://openalex.org/P4310315673
locations[0].license
locations[0].pdf_url	http://www.cell.com/article/S2211124716306866/pdf
locations[0].version	publishedVersion
locations[0].raw_type	journal-article
locations[0].license_id
locations[0].is_accepted	True
locations[0].is_published	True
locations[0].raw_source_name	Cell Reports
locations[0].landing_page_url	https://doi.org/10.1016/j.celrep.2016.05.073
locations[1].id	pmid:27320916
locations[1].is_oa	False
locations[1].source.id	https://openalex.org/S4306525036
locations[1].source.issn
locations[1].source.type	repository
locations[1].source.is_oa	False
locations[1].source.issn_l
locations[1].source.is_core	False
locations[1].source.is_in_doaj	False
locations[1].source.display_name	PubMed
locations[1].source.host_organization	https://openalex.org/I1299303238
locations[1].source.host_organization_name	National Institutes of Health
locations[1].source.host_organization_lineage	https://openalex.org/I1299303238
locations[1].license
locations[1].pdf_url
locations[1].version	publishedVersion
locations[1].raw_type
locations[1].license_id
locations[1].is_accepted	True
locations[1].is_published	True
locations[1].raw_source_name	Cell reports
locations[1].landing_page_url	https://pubmed.ncbi.nlm.nih.gov/27320916
locations[2].id	pmh:oai:doaj.org/article:266e49fa1aa343f48941d304bb2ad84b
locations[2].is_oa	True
locations[2].source.id	https://openalex.org/S4306401280
locations[2].source.issn
locations[2].source.type	repository
locations[2].source.is_oa	False
locations[2].source.issn_l
locations[2].source.is_core	False
locations[2].source.is_in_doaj	False
locations[2].source.display_name	DOAJ (DOAJ: Directory of Open Access Journals)
locations[2].source.host_organization
locations[2].source.host_organization_name
locations[2].source.host_organization_lineage
locations[2].license	cc-by-sa
locations[2].pdf_url
locations[2].version	submittedVersion
locations[2].raw_type	article
locations[2].license_id	https://openalex.org/licenses/cc-by-sa
locations[2].is_accepted	False
locations[2].is_published	False
locations[2].raw_source_name	Cell Reports, Vol 16, Iss 1, Pp 48-55 (2016)
locations[2].landing_page_url	https://doaj.org/article/266e49fa1aa343f48941d304bb2ad84b
locations[3].id	pmh:oai:pubmedcentral.nih.gov:4927351
locations[3].is_oa	True
locations[3].source.id	https://openalex.org/S2764455111
locations[3].source.issn
locations[3].source.type	repository
locations[3].source.is_oa	False
locations[3].source.issn_l
locations[3].source.is_core	False
locations[3].source.is_in_doaj	False
locations[3].source.display_name	PubMed Central
locations[3].source.host_organization	https://openalex.org/I1299303238
locations[3].source.host_organization_name	National Institutes of Health
locations[3].source.host_organization_lineage	https://openalex.org/I1299303238
locations[3].license
locations[3].pdf_url
locations[3].version	submittedVersion
locations[3].raw_type	Text
locations[3].license_id
locations[3].is_accepted	False
locations[3].is_published	False
locations[3].raw_source_name	Cell Rep
locations[3].landing_page_url	https://www.ncbi.nlm.nih.gov/pmc/articles/4927351
locations[4].id	pmh:oai:epub.ub.uni-muenchen.de:37755
locations[4].is_oa	False
locations[4].source.id	https://openalex.org/S4306401845
locations[4].source.issn
locations[4].source.type	repository
locations[4].source.is_oa	False
locations[4].source.issn_l
locations[4].source.is_core	False
locations[4].source.is_in_doaj	False
locations[4].source.display_name	Open access LMU (Ludwid Maxmilian's Universitat Munchen)
locations[4].source.host_organization	https://openalex.org/I8204097
locations[4].source.host_organization_name	Ludwig-Maximilians-Universität München
locations[4].source.host_organization_lineage	https://openalex.org/I8204097
locations[4].license
locations[4].pdf_url
locations[4].version	submittedVersion
locations[4].raw_type	doc-type:article
locations[4].license_id
locations[4].is_accepted	False
locations[4].is_published	False
locations[4].raw_source_name	Cell Reports
locations[4].landing_page_url	http://nbn-resolving.de/urn:nbn:de:bvb:19-epub-37755-3
indexed_in	crossref, doaj, pubmed
authorships[0].author.id	https://openalex.org/A5001955670
authorships[0].author.orcid	https://orcid.org/0000-0003-4691-7773
authorships[0].author.display_name	Pedro P. Rocha
authorships[0].countries	US
authorships[0].affiliations[0].institution_ids	https://openalex.org/I57206974
authorships[0].affiliations[0].raw_affiliation_string	Department of Pathology, New York University School of Medicine, New York, NY 10016, USA
authorships[0].institutions[0].id	https://openalex.org/I57206974
authorships[0].institutions[0].ror	https://ror.org/0190ak572
authorships[0].institutions[0].type	education
authorships[0].institutions[0].lineage	https://openalex.org/I57206974
authorships[0].institutions[0].country_code	US
authorships[0].institutions[0].display_name	New York University
authorships[0].author_position	first
authorships[0].raw_author_name	Pedro P. Rocha
authorships[0].is_corresponding	True
authorships[0].raw_affiliation_strings	Department of Pathology, New York University School of Medicine, New York, NY 10016, USA
authorships[1].author.id	https://openalex.org/A5022908335
authorships[1].author.orcid	https://orcid.org/0000-0002-5450-1455
authorships[1].author.display_name	Ramya Raviram
authorships[1].countries	US
authorships[1].affiliations[0].institution_ids	https://openalex.org/I57206974
authorships[1].affiliations[0].raw_affiliation_string	Department of Pathology, New York University School of Medicine, New York, NY 10016, USA
authorships[1].affiliations[1].institution_ids	https://openalex.org/I57206974
authorships[1].affiliations[1].raw_affiliation_string	Department of Biology, New York University, New York, NY 10003, USA
authorships[1].institutions[0].id	https://openalex.org/I57206974
authorships[1].institutions[0].ror	https://ror.org/0190ak572
authorships[1].institutions[0].type	education
authorships[1].institutions[0].lineage	https://openalex.org/I57206974
authorships[1].institutions[0].country_code	US
authorships[1].institutions[0].display_name	New York University
authorships[1].author_position	middle
authorships[1].raw_author_name	Ramya Raviram
authorships[1].is_corresponding	False
authorships[1].raw_affiliation_strings	Department of Biology, New York University, New York, NY 10003, USA, Department of Pathology, New York University School of Medicine, New York, NY 10016, USA
authorships[2].author.id	https://openalex.org/A5100714950
authorships[2].author.orcid	https://orcid.org/0000-0001-9104-8488
authorships[2].author.display_name	Yi Fu
authorships[2].countries	US
authorships[2].affiliations[0].institution_ids	https://openalex.org/I57206974
authorships[2].affiliations[0].raw_affiliation_string	Department of Pathology, New York University School of Medicine, New York, NY 10016, USA
authorships[2].institutions[0].id	https://openalex.org/I57206974
authorships[2].institutions[0].ror	https://ror.org/0190ak572
authorships[2].institutions[0].type	education
authorships[2].institutions[0].lineage	https://openalex.org/I57206974
authorships[2].institutions[0].country_code	US
authorships[2].institutions[0].display_name	New York University
authorships[2].author_position	middle
authorships[2].raw_author_name	Yi Fu
authorships[2].is_corresponding	False
authorships[2].raw_affiliation_strings	Department of Pathology, New York University School of Medicine, New York, NY 10016, USA
authorships[3].author.id	https://openalex.org/A5100349747
authorships[3].author.orcid	https://orcid.org/0000-0001-7176-409X
authorships[3].author.display_name	Jung‐Hyun Kim
authorships[3].countries	US
authorships[3].affiliations[0].institution_ids	https://openalex.org/I57206974
authorships[3].affiliations[0].raw_affiliation_string	Department of Pathology, New York University School of Medicine, New York, NY 10016, USA
authorships[3].institutions[0].id	https://openalex.org/I57206974
authorships[3].institutions[0].ror	https://ror.org/0190ak572
authorships[3].institutions[0].type	education
authorships[3].institutions[0].lineage	https://openalex.org/I57206974
authorships[3].institutions[0].country_code	US
authorships[3].institutions[0].display_name	New York University
authorships[3].author_position	middle
authorships[3].raw_author_name	JungHyun Kim
authorships[3].is_corresponding	False
authorships[3].raw_affiliation_strings	Department of Pathology, New York University School of Medicine, New York, NY 10016, USA
authorships[4].author.id	https://openalex.org/A5013091726
authorships[4].author.orcid	https://orcid.org/0000-0002-4365-4069
authorships[4].author.display_name	Vincent Luo
authorships[4].countries	US
authorships[4].affiliations[0].institution_ids	https://openalex.org/I57206974
authorships[4].affiliations[0].raw_affiliation_string	Department of Pathology, New York University School of Medicine, New York, NY 10016, USA
authorships[4].institutions[0].id	https://openalex.org/I57206974
authorships[4].institutions[0].ror	https://ror.org/0190ak572
authorships[4].institutions[0].type	education
authorships[4].institutions[0].lineage	https://openalex.org/I57206974
authorships[4].institutions[0].country_code	US
authorships[4].institutions[0].display_name	New York University
authorships[4].author_position	middle
authorships[4].raw_author_name	Vincent M. Luo
authorships[4].is_corresponding	False
authorships[4].raw_affiliation_strings	Department of Pathology, New York University School of Medicine, New York, NY 10016, USA
authorships[5].author.id	https://openalex.org/A5014618798
authorships[5].author.orcid	https://orcid.org/0009-0000-2891-9156
authorships[5].author.display_name	Arafat Aljoufi
authorships[5].countries	US
authorships[5].affiliations[0].institution_ids	https://openalex.org/I57206974
authorships[5].affiliations[0].raw_affiliation_string	Department of Pathology, New York University School of Medicine, New York, NY 10016, USA
authorships[5].institutions[0].id	https://openalex.org/I57206974
authorships[5].institutions[0].ror	https://ror.org/0190ak572
authorships[5].institutions[0].type	education
authorships[5].institutions[0].lineage	https://openalex.org/I57206974
authorships[5].institutions[0].country_code	US
authorships[5].institutions[0].display_name	New York University
authorships[5].author_position	middle
authorships[5].raw_author_name	Arafat Aljoufi
authorships[5].is_corresponding	False
authorships[5].raw_affiliation_strings	Department of Pathology, New York University School of Medicine, New York, NY 10016, USA
authorships[6].author.id	https://openalex.org/A5089743440
authorships[6].author.orcid	https://orcid.org/0000-0003-2581-6498
authorships[6].author.display_name	Emily Swanzey
authorships[6].countries	US
authorships[6].affiliations[0].institution_ids	https://openalex.org/I57206974
authorships[6].affiliations[0].raw_affiliation_string	Department of Developmental Genetics, New York University School of Medicine, New York, NY 10016, USA
authorships[6].institutions[0].id	https://openalex.org/I57206974
authorships[6].institutions[0].ror	https://ror.org/0190ak572
authorships[6].institutions[0].type	education
authorships[6].institutions[0].lineage	https://openalex.org/I57206974
authorships[6].institutions[0].country_code	US
authorships[6].institutions[0].display_name	New York University
authorships[6].author_position	middle
authorships[6].raw_author_name	Emily Swanzey
authorships[6].is_corresponding	False
authorships[6].raw_affiliation_strings	Department of Developmental Genetics, New York University School of Medicine, New York, NY 10016, USA
authorships[7].author.id	https://openalex.org/A5081776528
authorships[7].author.orcid
authorships[7].author.display_name	Alessandra Pasquarella
authorships[7].countries	DE
authorships[7].affiliations[0].institution_ids	https://openalex.org/I189554337, https://openalex.org/I8204097
authorships[7].affiliations[0].raw_affiliation_string	Ludwig Maximilians University and Munich Center for Integrated Protein Science (CiPSM), Biomedical Center, Planegg-Martinsried 80336, Germany
authorships[7].institutions[0].id	https://openalex.org/I189554337
authorships[7].institutions[0].ror	https://ror.org/032hzb643
authorships[7].institutions[0].type	other
authorships[7].institutions[0].lineage	https://openalex.org/I149899117, https://openalex.org/I189554337, https://openalex.org/I62916508, https://openalex.org/I8204097
authorships[7].institutions[0].country_code	DE
authorships[7].institutions[0].display_name	Center for Integrated Protein Science Munich
authorships[7].institutions[1].id	https://openalex.org/I8204097
authorships[7].institutions[1].ror	https://ror.org/05591te55
authorships[7].institutions[1].type	education
authorships[7].institutions[1].lineage	https://openalex.org/I8204097
authorships[7].institutions[1].country_code	DE
authorships[7].institutions[1].display_name	Ludwig-Maximilians-Universität München
authorships[7].author_position	middle
authorships[7].raw_author_name	Alessandra Pasquarella
authorships[7].is_corresponding	False
authorships[7].raw_affiliation_strings	Ludwig Maximilians University and Munich Center for Integrated Protein Science (CiPSM), Biomedical Center, Planegg-Martinsried 80336, Germany
authorships[8].author.id	https://openalex.org/A5005292414
authorships[8].author.orcid	https://orcid.org/0000-0001-8270-2687
authorships[8].author.display_name	Alessia Balestrini
authorships[8].countries	US
authorships[8].affiliations[0].institution_ids	https://openalex.org/I1334819555
authorships[8].affiliations[0].raw_affiliation_string	Molecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
authorships[8].institutions[0].id	https://openalex.org/I1334819555
authorships[8].institutions[0].ror	https://ror.org/02yrq0923
authorships[8].institutions[0].type	healthcare
authorships[8].institutions[0].lineage	https://openalex.org/I1334819555
authorships[8].institutions[0].country_code	US
authorships[8].institutions[0].display_name	Memorial Sloan Kettering Cancer Center
authorships[8].author_position	middle
authorships[8].raw_author_name	Alessia Balestrini
authorships[8].is_corresponding	False
authorships[8].raw_affiliation_strings	Molecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
authorships[9].author.id	https://openalex.org/A5002268742
authorships[9].author.orcid	https://orcid.org/0000-0002-0232-3116
authorships[9].author.display_name	Emily R. Miraldi
authorships[9].countries	US
authorships[9].affiliations[0].institution_ids	https://openalex.org/I4210107338
authorships[9].affiliations[0].raw_affiliation_string	Simons Center for Data Analysis, New York, NY 10010, USA
authorships[9].institutions[0].id	https://openalex.org/I4210107338
authorships[9].institutions[0].ror	https://ror.org/01cmst727
authorships[9].institutions[0].type	nonprofit
authorships[9].institutions[0].lineage	https://openalex.org/I4210107338
authorships[9].institutions[0].country_code	US
authorships[9].institutions[0].display_name	Simons Foundation
authorships[9].author_position	middle
authorships[9].raw_author_name	Emily R. Miraldi
authorships[9].is_corresponding	False
authorships[9].raw_affiliation_strings	Simons Center for Data Analysis, New York, NY 10010, USA
authorships[10].author.id	https://openalex.org/A5055203249
authorships[10].author.orcid	https://orcid.org/0000-0003-4354-7906
authorships[10].author.display_name	Richard Bonneau
authorships[10].countries	US
authorships[10].affiliations[0].institution_ids	https://openalex.org/I57206974
authorships[10].affiliations[0].raw_affiliation_string	Department of Biology, New York University, New York, NY 10003, USA
authorships[10].affiliations[1].institution_ids	https://openalex.org/I4210107338
authorships[10].affiliations[1].raw_affiliation_string	Simons Center for Data Analysis, New York, NY 10010, USA
authorships[10].affiliations[2].institution_ids	https://openalex.org/I36672615
authorships[10].affiliations[2].raw_affiliation_string	Department of Computer Science, Courant Institute of Mathematical Sciences, New York, NY 10012, USA
authorships[10].institutions[0].id	https://openalex.org/I36672615
authorships[10].institutions[0].ror	https://ror.org/037tm7f56
authorships[10].institutions[0].type	education
authorships[10].institutions[0].lineage	https://openalex.org/I36672615, https://openalex.org/I57206974
authorships[10].institutions[0].country_code	US
authorships[10].institutions[0].display_name	Courant Institute of Mathematical Sciences
authorships[10].institutions[1].id	https://openalex.org/I57206974
authorships[10].institutions[1].ror	https://ror.org/0190ak572
authorships[10].institutions[1].type	education
authorships[10].institutions[1].lineage	https://openalex.org/I57206974
authorships[10].institutions[1].country_code	US
authorships[10].institutions[1].display_name	New York University
authorships[10].institutions[2].id	https://openalex.org/I4210107338
authorships[10].institutions[2].ror	https://ror.org/01cmst727
authorships[10].institutions[2].type	nonprofit
authorships[10].institutions[2].lineage	https://openalex.org/I4210107338
authorships[10].institutions[2].country_code	US
authorships[10].institutions[2].display_name	Simons Foundation
authorships[10].author_position	middle
authorships[10].raw_author_name	Richard Bonneau
authorships[10].is_corresponding	False
authorships[10].raw_affiliation_strings	Department of Biology, New York University, New York, NY 10003, USA, Department of Computer Science, Courant Institute of Mathematical Sciences, New York, NY 10012, USA, Simons Center for Data Analysis, New York, NY 10010, USA
authorships[11].author.id	https://openalex.org/A5013956193
authorships[11].author.orcid	https://orcid.org/0000-0001-5102-5679
authorships[11].author.display_name	John H.J. Petrini
authorships[11].countries	US
authorships[11].affiliations[0].institution_ids	https://openalex.org/I1334819555
authorships[11].affiliations[0].raw_affiliation_string	Molecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
authorships[11].institutions[0].id	https://openalex.org/I1334819555
authorships[11].institutions[0].ror	https://ror.org/02yrq0923
authorships[11].institutions[0].type	healthcare
authorships[11].institutions[0].lineage	https://openalex.org/I1334819555
authorships[11].institutions[0].country_code	US
authorships[11].institutions[0].display_name	Memorial Sloan Kettering Cancer Center
authorships[11].author_position	middle
authorships[11].raw_author_name	John Petrini
authorships[11].is_corresponding	False
authorships[11].raw_affiliation_strings	Molecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
authorships[12].author.id	https://openalex.org/A5084721168
authorships[12].author.orcid	https://orcid.org/0000-0003-4940-6135
authorships[12].author.display_name	Gunnar Schotta
authorships[12].countries	DE
authorships[12].affiliations[0].institution_ids	https://openalex.org/I189554337, https://openalex.org/I8204097
authorships[12].affiliations[0].raw_affiliation_string	Ludwig Maximilians University and Munich Center for Integrated Protein Science (CiPSM), Biomedical Center, Planegg-Martinsried 80336, Germany
authorships[12].institutions[0].id	https://openalex.org/I189554337
authorships[12].institutions[0].ror	https://ror.org/032hzb643
authorships[12].institutions[0].type	other
authorships[12].institutions[0].lineage	https://openalex.org/I149899117, https://openalex.org/I189554337, https://openalex.org/I62916508, https://openalex.org/I8204097
authorships[12].institutions[0].country_code	DE
authorships[12].institutions[0].display_name	Center for Integrated Protein Science Munich
authorships[12].institutions[1].id	https://openalex.org/I8204097
authorships[12].institutions[1].ror	https://ror.org/05591te55
authorships[12].institutions[1].type	education
authorships[12].institutions[1].lineage	https://openalex.org/I8204097
authorships[12].institutions[1].country_code	DE
authorships[12].institutions[1].display_name	Ludwig-Maximilians-Universität München
authorships[12].author_position	middle
authorships[12].raw_author_name	Gunnar Schotta
authorships[12].is_corresponding	False
authorships[12].raw_affiliation_strings	Ludwig Maximilians University and Munich Center for Integrated Protein Science (CiPSM), Biomedical Center, Planegg-Martinsried 80336, Germany
authorships[13].author.id	https://openalex.org/A5083464518
authorships[13].author.orcid	https://orcid.org/0000-0002-4145-1516
authorships[13].author.display_name	Jane A. Skok
authorships[13].countries	US
authorships[13].affiliations[0].institution_ids	https://openalex.org/I57206974
authorships[13].affiliations[0].raw_affiliation_string	Department of Pathology, New York University School of Medicine, New York, NY 10016, USA
authorships[13].institutions[0].id	https://openalex.org/I57206974
authorships[13].institutions[0].ror	https://ror.org/0190ak572
authorships[13].institutions[0].type	education
authorships[13].institutions[0].lineage	https://openalex.org/I57206974
authorships[13].institutions[0].country_code	US
authorships[13].institutions[0].display_name	New York University
authorships[13].author_position	last
authorships[13].raw_author_name	Jane A. Skok
authorships[13].is_corresponding	True
authorships[13].raw_affiliation_strings	Department of Pathology, New York University School of Medicine, New York, NY 10016, USA
has_content.pdf	True
has_content.grobid_xml	True
is_paratext	False
open_access.is_oa	True
open_access.oa_url	http://www.cell.com/article/S2211124716306866/pdf
open_access.oa_status	gold
open_access.any_repository_has_fulltext	False
created_date	2025-10-10T00:00:00
display_name	A Damage-Independent Role for 53BP1 that Impacts Break Order and Igh Architecture during Class Switch Recombination
has_fulltext	False
is_retracted	False
updated_date	2025-11-06T03:46:38.306776
primary_topic.id	https://openalex.org/T10123
primary_topic.field.id	https://openalex.org/fields/13
primary_topic.field.display_name	Biochemistry, Genetics and Molecular Biology
primary_topic.score	0.9991999864578247
primary_topic.domain.id	https://openalex.org/domains/1
primary_topic.domain.display_name	Life Sciences
primary_topic.subfield.id	https://openalex.org/subfields/1312
primary_topic.subfield.display_name	Molecular Biology
primary_topic.display_name	DNA Repair Mechanisms
related_works	https://openalex.org/W1580273679, https://openalex.org/W2134047133, https://openalex.org/W2463687386, https://openalex.org/W63754614, https://openalex.org/W2057154782, https://openalex.org/W2064813393, https://openalex.org/W2021824933, https://openalex.org/W2623037965, https://openalex.org/W2049404127, https://openalex.org/W147552635
cited_by_count	36
counts_by_year[0].year	2025
counts_by_year[0].cited_by_count	2
counts_by_year[1].year	2024
counts_by_year[1].cited_by_count	4
counts_by_year[2].year	2023
counts_by_year[2].cited_by_count	2
counts_by_year[3].year	2022
counts_by_year[3].cited_by_count	4
counts_by_year[4].year	2021
counts_by_year[4].cited_by_count	2
counts_by_year[5].year	2020
counts_by_year[5].cited_by_count	5
counts_by_year[6].year	2019
counts_by_year[6].cited_by_count	8
counts_by_year[7].year	2018
counts_by_year[7].cited_by_count	4
counts_by_year[8].year	2017
counts_by_year[8].cited_by_count	3
counts_by_year[9].year	2016
counts_by_year[9].cited_by_count	2
locations_count	5
best_oa_location.id	doi:10.1016/j.celrep.2016.05.073
best_oa_location.is_oa	True
best_oa_location.source.id	https://openalex.org/S169236886
best_oa_location.source.issn	2211-1247, 2639-1856
best_oa_location.source.type	journal
best_oa_location.source.is_oa	True
best_oa_location.source.issn_l	2211-1247
best_oa_location.source.is_core	True
best_oa_location.source.is_in_doaj	True
best_oa_location.source.display_name	Cell Reports
best_oa_location.source.host_organization	https://openalex.org/P4310315673
best_oa_location.source.host_organization_name	Cell Press
best_oa_location.source.host_organization_lineage	https://openalex.org/P4310315673
best_oa_location.license
best_oa_location.pdf_url	http://www.cell.com/article/S2211124716306866/pdf
best_oa_location.version	publishedVersion
best_oa_location.raw_type	journal-article
best_oa_location.license_id
best_oa_location.is_accepted	True
best_oa_location.is_published	True
best_oa_location.raw_source_name	Cell Reports
best_oa_location.landing_page_url	https://doi.org/10.1016/j.celrep.2016.05.073
primary_location.id	doi:10.1016/j.celrep.2016.05.073
primary_location.is_oa	True
primary_location.source.id	https://openalex.org/S169236886
primary_location.source.issn	2211-1247, 2639-1856
primary_location.source.type	journal
primary_location.source.is_oa	True
primary_location.source.issn_l	2211-1247
primary_location.source.is_core	True
primary_location.source.is_in_doaj	True
primary_location.source.display_name	Cell Reports
primary_location.source.host_organization	https://openalex.org/P4310315673
primary_location.source.host_organization_name	Cell Press
primary_location.source.host_organization_lineage	https://openalex.org/P4310315673
primary_location.license
primary_location.pdf_url	http://www.cell.com/article/S2211124716306866/pdf
primary_location.version	publishedVersion
primary_location.raw_type	journal-article
primary_location.license_id
primary_location.is_accepted	True
primary_location.is_published	True
primary_location.raw_source_name	Cell Reports
primary_location.landing_page_url	https://doi.org/10.1016/j.celrep.2016.05.073
publication_date	2016-06-01
publication_year	2016
referenced_works	https://openalex.org/W2049262839, https://openalex.org/W2162881608, https://openalex.org/W2052981964, https://openalex.org/W2068973408, https://openalex.org/W2157899948, https://openalex.org/W2067228541, https://openalex.org/W2075525218, https://openalex.org/W2151925648, https://openalex.org/W2097627856, https://openalex.org/W1781139164, https://openalex.org/W2096391864, https://openalex.org/W1960323088, https://openalex.org/W2146273112, https://openalex.org/W1891786677, https://openalex.org/W2146355613, https://openalex.org/W2276468219, https://openalex.org/W2062725457, https://openalex.org/W2053200644, https://openalex.org/W2090836500, https://openalex.org/W2011198783, https://openalex.org/W2165605980, https://openalex.org/W2122117713, https://openalex.org/W2091243328, https://openalex.org/W2020609024, https://openalex.org/W2161212572, https://openalex.org/W2071787911, https://openalex.org/W2067427915, https://openalex.org/W1973062929, https://openalex.org/W2951733010, https://openalex.org/W2036339686, https://openalex.org/W1967825549, https://openalex.org/W2110146990, https://openalex.org/W2098801519, https://openalex.org/W2127261230, https://openalex.org/W1975506497, https://openalex.org/W2169474275, https://openalex.org/W2153622268, https://openalex.org/W1913397935, https://openalex.org/W2294748876, https://openalex.org/W2016448166, https://openalex.org/W2063488321
referenced_works_count	41
abstract_inverted_index
cited_by_percentile_year.max	99
cited_by_percentile_year.min	93
corresponding_author_ids	https://openalex.org/A5083464518, https://openalex.org/A5001955670
countries_distinct_count	2
institutions_distinct_count	14
corresponding_institution_ids	https://openalex.org/I57206974
citation_normalized_percentile.value	0.91678666
citation_normalized_percentile.is_in_top_1_percent	False
citation_normalized_percentile.is_in_top_10_percent	True