doi.org
A deep learning methodology for fully-automated quantification of calcific burden in high-resolution intravascular ultrasound images
September 2025 • Xingwei He, Mohamed O. Mohamed, Nicole Ng, Thamil Kumaran, Retesh Bajaj, Nathan Angelo Lecaros Yap, Emrah Erdoğan, Mehmet Eren, Anthony Mathur, Ahmet…
<title>Abstract</title> Purpose Quantification of the calcific burden is valuable in percutaneous coronary intervention (PCI) planning and in research to assess its changes after pharmacotherapies targeting plaque progression. In intravascular ultrasound (IVUS) images this analysis is currently performed manually and time consuming. To overcome these limitations, we introduce a deep-learning (DL) method for seamless detection of the calcific tissue Methods IVUS images from 197 vessels were analysed by an expert wh…