A lymph node lesion of hyper IL-6 syndrome mimicking plasmacytoma, IgG4-related disease, and Castleman disease Article Swipe
Kenta Matsui
,
Hiroshi Imai
,
Toshiaki Kobayashi
,
Minoru Mizutani
,
Midori Filiz Nishimura
,
Yasuharu Sato
,
Kennosuke Karube
,
M. Okada
,
Miki Usui
,
Keiki Kawakami
,
Tetsuya Murata
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.3960/jslrt.24039
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.3960/jslrt.24039
A 72-year-old male patient presented fatigue, anemia, elevated total protein, IgG, IgG4, IL-6, and vascular endothelial growth factor (VEGF) levels. Initial diagnostics suspected multiple myeloma. A plane computed tomography (CT) scan showed pneumonia and the enlargement of generalized lymph nodes. A lymph node biopsy revealed a mix of immature and mature plasma cells, significant IgG4-positive cells, and IL-6-secreting plasma cells, mimicking plasmacytoma, IgG4-related disease, and Castleman disease, ultimately leading to a diagnosis of hyper IL-6 syndrome. Treatment with antibiotics improved the patient's condition without the need for additional therapies, including tocilizumab.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.3960/jslrt.24039
- OA Status
- gold
- References
- 18
- Related Works
- 10
- OpenAlex ID
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All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4405744672Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.3960/jslrt.24039Digital Object Identifier
- Title
-
A lymph node lesion of hyper IL-6 syndrome mimicking plasmacytoma, IgG4-related disease, and Castleman diseaseWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2024Year of publication
- Publication date
-
2024-12-24Full publication date if available
- Authors
-
Kenta Matsui, Hiroshi Imai, Toshiaki Kobayashi, Minoru Mizutani, Midori Filiz Nishimura, Yasuharu Sato, Kennosuke Karube, M. Okada, Miki Usui, Keiki Kawakami, Tetsuya MurataList of authors in order
- Landing page
-
https://doi.org/10.3960/jslrt.24039Publisher landing page
- Open access
-
YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
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https://doi.org/10.3960/jslrt.24039Direct OA link when available
- Concepts
-
Castleman disease, Medicine, Disease, Pathology, Lesion, Lymph node, Plasmacytoma, IgG4-related disease, Multiple myeloma, ImmunologyTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
0Total citation count in OpenAlex
- References (count)
-
18Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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