doi.org
A Mixture Method for Robust Detection HCV Early Diagnosis Biomarker with ML Approach and Molecular Docking
April 2023 • Maryam Gholizadeh, Joanna Łapczuk-Romańska, Mariola Post, Nina Komaniecka, Seyed Reza Mazlooman, Lars Kaderali, Marek Droździk
Given the substantial correlation between early diagnosis and prolonged patient survival in HCV patients, it is vital to identify a reliable and accessible biomarker. The purpose of this research was to identify accurate miRNA biomarkers to aid in the early diagnosis of HCV and to identify key target genes for anti-hepatic fibrosis therapeutics. The expression of 188 miRNAs in 42 HCV liver patients with different functional states and 23 normal livers were determined using RT-qPCR. After screening out differential…