A Multi-FPGA Implementation of FM-Index Based Genomic Pattern Search Article Swipe
YOU?
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· 2023
· Open Access
·
· DOI: https://doi.org/10.1587/transinf.2022edp7230
FPGA clusters that consist of multiple FPGA boards have been gaining interest in recent times. Massively parallel processing with a stand-alone heterogeneous FPGA cluster with SoC- style FPGAs and mid-scale FPGAs is promising with cost-performance benefit. Here, we propose such a heterogeneous FPGA cluster with FiC and M-KUBOS cluster. FiC consists of multiple boards, mounting middle scale Xilinx's FPGAs and DRAMs, which are tightly coupled with high-speed serial links. In addition, M-KUBOS boards are connected to FiC for ensuring high IO data transfer bandwidth. As an example of massively parallel processing, here we implement genomic pattern search. Next-generation sequencing (NGS) technology has revolutionized biological system related research by its high-speed, scalable and massive throughput. To analyze the genomic data, short read mapping technique is used where short Deoxyribonucleic acid (DNA) sequences are mapped relative to a known reference sequence. Although several pattern matching techniques are available, FM-index based pattern search is perfectly suitable for this task due to the fastest mapping from known indices. Since matching can be done in parallel for different data, the massively parallel computing which distributes data, executes in parallel and gathers the results can be applied. We also implement a data compression method where about 10 times reduction in data size is achieved. We found that a M-KUBOS board matches four FiC boards, and a system with six M-KUBOS boards and 24 FiC boards achieved 30 times faster than the software based implementation.
Related Topics
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1587/transinf.2022edp7230
- https://www.jstage.jst.go.jp/article/transinf/E106.D/11/E106.D_2022EDP7230/_pdf
- OA Status
- diamond
- References
- 44
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4388038182
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4388038182Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1587/transinf.2022edp7230Digital Object Identifier
- Title
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A Multi-FPGA Implementation of FM-Index Based Genomic Pattern SearchWork title
- Type
-
articleOpenAlex work type
- Language
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enPrimary language
- Publication year
-
2023Year of publication
- Publication date
-
2023-10-31Full publication date if available
- Authors
-
Ullah M. M. Imdad, Akram Ben Ahmed, Kazuei Hironaka, Kensuke Iizuka, Hideharu AmanoList of authors in order
- Landing page
-
https://doi.org/10.1587/transinf.2022edp7230Publisher landing page
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https://www.jstage.jst.go.jp/article/transinf/E106.D/11/E106.D_2022EDP7230/_pdfDirect link to full text PDF
- Open access
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YesWhether a free full text is available
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diamondOpen access status per OpenAlex
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https://www.jstage.jst.go.jp/article/transinf/E106.D/11/E106.D_2022EDP7230/_pdfDirect OA link when available
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Computer science, Massively parallel, Field-programmable gate array, Scalability, Parallel computing, Throughput, Reduction (mathematics), Computer hardware, Operating system, Geometry, Mathematics, WirelessTop concepts (fields/topics) attached by OpenAlex
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0Total citation count in OpenAlex
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44Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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