A multi-site MicroLED Optrode Array for Neural Interfacing Article Swipe
Niall McAlinden
,
Yunzhou Cheng
,
Robert Scharf
,
Enyuan Xie
,
Erdan Gu
,
Martin D. Dawson
,
Christopher F. Reiche
,
Rohit Sharma
,
Prashant Tathireddy
,
Loren Rieth
,
Steve Blair
,
Keith Mathieson
·
YOU?
·
· 2018
· Open Access
·
· DOI: https://doi.org/10.1101/480582
YOU?
·
· 2018
· Open Access
·
· DOI: https://doi.org/10.1101/480582
We present an electrically addressable optrode array capable of delivering light to 181 sites in the brain, each providing sufficient light to optogenetically excite hundreds of neurons in vivo , developed with the aim to allow behavioural studies in large mammals. The device is a glass microneedle array directly integrated with a custom fabricated microLED device, which delivers light to 100 needle tips and 81 interstitial surface sites, giving 2-level optogenetic excitation of neurons in vivo . Light delivery and thermal properties are evaluated, with the device capable of peak irradiances > 80 mW/mm 2 per needle at 50 ms pulse widths with tissue temperature increase less than 1 ° C. Future designs are explored through optical and thermal modelling and benchmarked against the current device.
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Metadata
- Type
- preprint
- Language
- en
- Landing Page
- https://doi.org/10.1101/480582
- https://www.biorxiv.org/content/biorxiv/early/2018/11/29/480582.full.pdf
- OA Status
- green
- Cited By
- 8
- References
- 33
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W2903407510
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Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W2903407510Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1101/480582Digital Object Identifier
- Title
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A multi-site MicroLED Optrode Array for Neural InterfacingWork title
- Type
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preprintOpenAlex work type
- Language
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enPrimary language
- Publication year
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2018Year of publication
- Publication date
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2018-11-29Full publication date if available
- Authors
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Niall McAlinden, Yunzhou Cheng, Robert Scharf, Enyuan Xie, Erdan Gu, Martin D. Dawson, Christopher F. Reiche, Rohit Sharma, Prashant Tathireddy, Loren Rieth, Steve Blair, Keith MathiesonList of authors in order
- Landing page
-
https://doi.org/10.1101/480582Publisher landing page
- PDF URL
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https://www.biorxiv.org/content/biorxiv/early/2018/11/29/480582.full.pdfDirect link to full text PDF
- Open access
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YesWhether a free full text is available
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-
greenOpen access status per OpenAlex
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https://www.biorxiv.org/content/biorxiv/early/2018/11/29/480582.full.pdfDirect OA link when available
- Concepts
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Optode, Interfacing, Optogenetics, Materials science, Thermal, Optoelectronics, Light guide, Excitation, Optics, Light source, Biomedical engineering, Computer science, Computer hardware, Electrical engineering, Physics, Engineering, Fluorescence, Biology, Meteorology, NeuroscienceTop concepts (fields/topics) attached by OpenAlex
- Cited by
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8Total citation count in OpenAlex
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2025: 1, 2024: 2, 2023: 3, 2020: 1, 2019: 1Per-year citation counts (last 5 years)
- References (count)
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33Number of works referenced by this work
- Related works (count)
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10Other works algorithmically related by OpenAlex
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