A multinational observational study identifying primary care patients at risk of overestimation of asthma control Article Swipe
Vicky Kritikos
,
David Price
,
Alberto Papi
,
Antonio Infantino
,
Björn Ställberg
,
Dermot Ryan
,
Federico Lavorini
,
Henry Chrystyn
,
John Haughney
,
Karin Lisspers
,
Kevin Gruffydd‐Jones
,
Miguel Román-Rodríguez
,
Svein Høegh Henrichsen
,
Thys van der Molen
,
Victoria Carter
,
Sinthia Bosnic‐Anticevich
·
YOU?
·
· 2019
· Open Access
·
· DOI: https://doi.org/10.1038/s41533-019-0156-4
YOU?
·
· 2019
· Open Access
·
· DOI: https://doi.org/10.1038/s41533-019-0156-4
Factors related to the discrepancy between patient-perceived and actual disease control remain unclear. Identifying patients at risk of overestimation of asthma control remains elusive. This study aimed to (i) investigate the relationship between patient-reported and actual level of asthma control (ii), compare the characteristics between patients who believe their asthma is well controlled that accurately report ‘well-controlled’ asthma with those that do not, and (iii) identify factors associated with inaccurately reported ‘well-controlled’ asthma. A historical, multinational, cross-sectional study using data from the iHARP (initiative Helping Asthma in Real-life Patients) review service for adults with asthma prescribed fixed-dose combination therapy. Data from 4274 patients were analysed. A major discrepancy between patient-reported and Global Initiative for Asthma defined asthma control was detected; 71.1% of patients who reported ‘well-controlled’ asthma were inaccurate in their perception despite receiving regular maintenance therapy. Significant differences were noted in age, gender, body mass index, education level, medication use, side effects, attitudes to preventer inhaler use, inhaler technique review and respiratory specialist review between patients who accurately reported ‘well-controlled’ asthma and those who did not. Independent risk factors associated with inaccurately reported ‘well-controlled’ asthma were: having taken a maximum of 5–12 puffs or more of reliever inhaler on at least one day within the previous 4 weeks; being female; having seen a respiratory specialist more than a year ago (rather than in the previous year); and having required oral corticosteroids for worsening asthma in the previous year. The study highlighted the significant hidden burden associated with under-recognition of poor asthma control, on the part of the patient and the need for targeted interventions designed to address the continuing discrepancy between perceived and actual disease control.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1038/s41533-019-0156-4
- https://www.nature.com/articles/s41533-019-0156-4.pdf
- OA Status
- gold
- Cited By
- 37
- References
- 48
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W2993723754
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W2993723754Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1038/s41533-019-0156-4Digital Object Identifier
- Title
-
A multinational observational study identifying primary care patients at risk of overestimation of asthma controlWork title
- Type
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articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2019Year of publication
- Publication date
-
2019-12-05Full publication date if available
- Authors
-
Vicky Kritikos, David Price, Alberto Papi, Antonio Infantino, Björn Ställberg, Dermot Ryan, Federico Lavorini, Henry Chrystyn, John Haughney, Karin Lisspers, Kevin Gruffydd‐Jones, Miguel Román-Rodríguez, Svein Høegh Henrichsen, Thys van der Molen, Victoria Carter, Sinthia Bosnic‐AnticevichList of authors in order
- Landing page
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https://doi.org/10.1038/s41533-019-0156-4Publisher landing page
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https://www.nature.com/articles/s41533-019-0156-4.pdfDirect link to full text PDF
- Open access
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YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
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https://www.nature.com/articles/s41533-019-0156-4.pdfDirect OA link when available
- Concepts
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Asthma, Medicine, Inhaler, Observational study, Body mass index, Pediatrics, Physical therapy, Intensive care medicine, Internal medicineTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
37Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 1, 2024: 6, 2023: 4, 2022: 6, 2021: 7Per-year citation counts (last 5 years)
- References (count)
-
48Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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