A novel placental tissue biologic, PTP-001, inhibits inflammatory and catabolic responses in vitro and prevents pain and cartilage degeneration in a rat model of osteoarthritis Article Swipe
Carl R. Flannery
,
Susie Seaman
,
K.E. Buddin
,
M.A. Nasert
,
Eric J. Semler
,
K.L. Kelley
,
Marc Long
,
Jacob Favret
,
A. Pavesio
,
R.F. Loeser
·
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.1016/j.joca.2021.03.022
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.1016/j.joca.2021.03.022
PTP-001 represents a promising biologic treatment for osteoarthritis, with a multi-modal mechanism of action that may contribute to symptom management and disease modification.
Related Topics
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1016/j.joca.2021.03.022
- OA Status
- hybrid
- Cited By
- 26
- References
- 49
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W3161282164
All OpenAlex metadata
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https://openalex.org/W3161282164Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1016/j.joca.2021.03.022Digital Object Identifier
- Title
-
A novel placental tissue biologic, PTP-001, inhibits inflammatory and catabolic responses in vitro and prevents pain and cartilage degeneration in a rat model of osteoarthritisWork title
- Type
-
articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2021Year of publication
- Publication date
-
2021-05-20Full publication date if available
- Authors
-
Carl R. Flannery, Susie Seaman, K.E. Buddin, M.A. Nasert, Eric J. Semler, K.L. Kelley, Marc Long, Jacob Favret, A. Pavesio, R.F. LoeserList of authors in order
- Landing page
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https://doi.org/10.1016/j.joca.2021.03.022Publisher landing page
- Open access
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YesWhether a free full text is available
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hybridOpen access status per OpenAlex
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https://doi.org/10.1016/j.joca.2021.03.022Direct OA link when available
- Concepts
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Osteoarthritis, Proinflammatory cytokine, Medicine, Chondrocyte, Monocyte, Inflammation, In vivo, Cartilage, Internal medicine, Matrix metalloproteinase, Endocrinology, Pharmacology, Pathology, Immunology, Biology, Anatomy, Alternative medicine, BiotechnologyTop concepts (fields/topics) attached by OpenAlex
- Cited by
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26Total citation count in OpenAlex
- Citations by year (recent)
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2025: 6, 2024: 6, 2023: 9, 2022: 5Per-year citation counts (last 5 years)
- References (count)
-
49Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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