A Novel UV-VIS Spectroscopic Approach for the Development and Validation of Benzoyl Peroxide Quantification Methods Article Swipe
Tien Nam Nguyen
,
Thành Tâm Nguyên
,
Therese Vu
,
Thi Phuong Thao Pham
,
Phuong N. H. Phạm
,
Tran Thi Luong
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.59070/jhs020624024
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.59070/jhs020624024
Objective: Benzoyl peroxide (BPO) is a widely used active ingredient in acne treatments, recognized for its antibacterial and exfoliating properties. This study aims to quantitatively determine the concentration of BPO in an acne cream using UV-Vis spectrophotometry. Methods: the method involves dissolving the cream in a suitable solvent and measuring its absorbance at a specific wavelength. The UV-Vis technique has demonstrated accuracy and reliability quantifying BPO in commercial formulations. This method is suitable for use in quality control and formulation standardization in the pharmaceutical and cosmetic industries. Results: the UV-Vis method was used to determine the concentration of BPO in the product. This quantitative analytical method was validated according to ICH guidelines at a wavelength of 235nm, range of determination is 4.8 µg/ml to 7.2 µg/ml. Conclusion: the proposed method for analyzing BPO content is simple, highly reliable and well-suited for use in laboratory settings.
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Metadata
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- Language
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- Landing Page
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- OA Status
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- OpenAlex ID
- https://openalex.org/W4411495694
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4411495694Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.59070/jhs020624024Digital Object Identifier
- Title
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A Novel UV-VIS Spectroscopic Approach for the Development and Validation of Benzoyl Peroxide Quantification MethodsWork title
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articleOpenAlex work type
- Language
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enPrimary language
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2025Year of publication
- Publication date
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2025-05-06Full publication date if available
- Authors
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Tien Nam Nguyen, Thành Tâm Nguyên, Therese Vu, Thi Phuong Thao Pham, Phuong N. H. Phạm, Tran Thi LuongList of authors in order
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https://doi.org/10.59070/jhs020624024Publisher landing page
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YesWhether a free full text is available
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diamondOpen access status per OpenAlex
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https://doi.org/10.59070/jhs020624024Direct OA link when available
- Concepts
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Benzoyl peroxide, Absorbance, Acne, Spectrophotometry, Chromatography, Solvent, Ultraviolet visible spectroscopy, Chemistry, Materials science, Dermatology, Organic chemistry, Medicine, Polymer, PolymerizationTop concepts (fields/topics) attached by OpenAlex
- Cited by
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0Total citation count in OpenAlex
- Related works (count)
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10Other works algorithmically related by OpenAlex
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