A proof-of-concept analysis of data from the first NHS clinic for young adults with comorbid cannabis use and psychotic disorders Article Swipe
Marta Di Forti
,
Brian Bond
,
Edoardo Spinazzola
,
Giulia Trotta
,
Joanne Lynn
,
Robert Malkin
,
Naba Kamran Siddiqui
,
S Demir
,
Titilayomi Opadokun
,
Perry B.M. Leung
,
Zhikun Li
,
Andrea Quattrone
,
David Baxter
,
Elizabeth Appiah‐Kusi
,
Tom P. Freeman
,
Hannah Walsh
,
Tommaso Squeri
,
Daria Semikina
,
Felicity Amberson-Jones
,
Isabelle Austin-Zimmerman
,
Tim Meynen
,
Diego Quattrone
,
Robin Murray
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1192/bjo.2024.782
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1192/bjo.2024.782
Background Cannabis use severely affects the outcome of people with psychotic disorders, yet there is a lack of treatments. To address this, in 2019 the National Health Service (NHS) Cannabis Clinic for Psychosis (CCP) was developed to support adults suffering from psychosis to reduce and/or stop their cannabis use. Aims Examine outcome data from the first 46 individuals to complete the CCP's intervention. Method The sample ( N = 46) consisted of adults (aged ≥ 18) with psychosis under the care of the South London and Maudsley NHS Foundation Trust, referred to the CCP between January 2020 and February 2023, who completed their intervention by September 2023. Clinical and functional measures were collected before (T0) and after (T1) the CCP intervention (one-to-one sessions and peer group attendance). Primary outcomes were changes in the Cannabis Use Disorders Identification Test-Revised (CUDIT-R) score and pattern of cannabis use. Secondary outcomes included T0–T1 changes in measures of delusions, paranoia, depression, anxiety and functioning. Results A reduction in the mean CUDIT-R score was observed between T0 (mean difference = 17.10, 95% CI = 15.54–18.67) and T1, with 73.91% of participants achieving abstinence and 26.09% reducing the frequency and potency of their use. Significant improvements in all clinical and functional outcomes were observed, with 90.70% being in work or education at T1 compared with 8.70% at T0. The variance in CUDIT-R scores explained between 34 and 64% of the variance in our secondary measures. Conclusions The CCP intervention is a feasible strategy to support cannabis use cessation/reduction and improve clinical and functional outcomes of people with psychotic disorders.
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Metadata
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- https://doi.org/10.1192/bjo.2024.782
- https://www.cambridge.org/core/services/aop-cambridge-core/content/view/230A8A7BCD3F53D64241DBEB00C74BE2/S2056472424007828a.pdf/div-class-title-a-proof-of-concept-analysis-of-data-from-the-first-nhs-clinic-for-young-adults-with-comorbid-cannabis-use-and-psychotic-disorders-div.pdf
- OA Status
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- OpenAlex ID
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All OpenAlex metadata
Raw OpenAlex JSON
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https://openalex.org/W4405337175Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1192/bjo.2024.782Digital Object Identifier
- Title
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A proof-of-concept analysis of data from the first NHS clinic for young adults with comorbid cannabis use and psychotic disordersWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2024Year of publication
- Publication date
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2024-12-12Full publication date if available
- Authors
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Marta Di Forti, Brian Bond, Edoardo Spinazzola, Giulia Trotta, Joanne Lynn, Robert Malkin, Naba Kamran Siddiqui, S Demir, Titilayomi Opadokun, Perry B.M. Leung, Zhikun Li, Andrea Quattrone, David Baxter, Elizabeth Appiah‐Kusi, Tom P. Freeman, Hannah Walsh, Tommaso Squeri, Daria Semikina, Felicity Amberson-Jones, Isabelle Austin-Zimmerman, Tim Meynen, Diego Quattrone, Robin MurrayList of authors in order
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https://doi.org/10.1192/bjo.2024.782Publisher landing page
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https://www.cambridge.org/core/services/aop-cambridge-core/content/view/230A8A7BCD3F53D64241DBEB00C74BE2/S2056472424007828a.pdf/div-class-title-a-proof-of-concept-analysis-of-data-from-the-first-nhs-clinic-for-young-adults-with-comorbid-cannabis-use-and-psychotic-disorders-div.pdfDirect link to full text PDF
- Open access
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YesWhether a free full text is available
- OA status
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goldOpen access status per OpenAlex
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https://www.cambridge.org/core/services/aop-cambridge-core/content/view/230A8A7BCD3F53D64241DBEB00C74BE2/S2056472424007828a.pdf/div-class-title-a-proof-of-concept-analysis-of-data-from-the-first-nhs-clinic-for-young-adults-with-comorbid-cannabis-use-and-psychotic-disorders-div.pdfDirect OA link when available
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1Total citation count in OpenAlex
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2025: 1Per-year citation counts (last 5 years)
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10Other works algorithmically related by OpenAlex
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