A randomized controlled trial of a self-guided mobile app targeting repetitive negative thought to prevent depression in university students: study protocol of the Nurture-U Reducing Worry prevention trial Article Swipe
ER Watkins
,
Deborah Phillips
,
Treena Cranston
,
H Choueiri
,
Michelle Newton
,
Helen Cook
,
Gordon Taylor
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1186/s12888-024-06079-2
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1186/s12888-024-06079-2
Background Tackling poor mental health in university students has been identified as a priority in higher education. However, there are few evidence-based prevention initiatives designed for students. Repetitive Negative Thought (RNT, e.g. worry, rumination) is elevated in university students and is a well-established vulnerability factor for anxiety and depression. Furthermore, there are now evidence-based cognitive-behavioural interventions to tackle RNT. A mobile self-help cognitive-behavioural app targeting RNT, adapted for students may therefore be an effective, scalable, and acceptable way to improve prevention in students. Methods An online single blind, two-arm parallel-group Randomised Controlled Trial (RCT) to examine the incidence of major depression and symptoms of anxiety and depression across 12 months in university students aged over 16 who screen into the study with self-reported high levels of worry and/or rumination and no current diagnosis of major depression. Eligible participants will be randomised to the active intervention arm (usual practice plus using a self-guided mobile app targeting RNT) or to the control arm (usual practice). In total, 648 participants aged over 16, with no current major depression, bipolar disorder or psychosis will be recruited from UK universities. Assessments will take place at baseline (pre-randomisation), 3 months and 12 months post- randomisation. Primary endpoint and outcome is incidence of major depression as determined by self-reported diagnostic criteria at 12-month follow-up. Depressive symptoms, anxiety, well-being, health-related quality of life, functioning and academic outcomes are secondary outcomes. Compliance, adverse events, and potentially mediating variables will be carefully monitored. Discussion The trial aims to provide a better understanding of the causal role of tackling RNT (worry, rumination) using a self-help mobile app with respect to preventing depression in university students. This knowledge will be used to develop and disseminate innovative evidence-based, feasible, and effective mobile-health public health strategies for preventing common mental health problems. Trial registration https://www.isrctn.com/ISRCTN86795807 Date of registration: 27 October 2022
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1186/s12888-024-06079-2
- OA Status
- gold
- Cited By
- 2
- References
- 56
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4403073346
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4403073346Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1186/s12888-024-06079-2Digital Object Identifier
- Title
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A randomized controlled trial of a self-guided mobile app targeting repetitive negative thought to prevent depression in university students: study protocol of the Nurture-U Reducing Worry prevention trialWork title
- Type
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articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2024Year of publication
- Publication date
-
2024-10-02Full publication date if available
- Authors
-
ER Watkins, Deborah Phillips, Treena Cranston, H Choueiri, Michelle Newton, Helen Cook, Gordon TaylorList of authors in order
- Landing page
-
https://doi.org/10.1186/s12888-024-06079-2Publisher landing page
- Open access
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YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
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https://doi.org/10.1186/s12888-024-06079-2Direct OA link when available
- Concepts
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Worry, Randomized controlled trial, Anxiety, Rumination, Mental health, Clinical psychology, Quality of life (healthcare), Psychiatry, Depression (economics), Psychological intervention, Psychology, Medicine, Cognition, Internal medicine, Psychotherapist, Economics, MacroeconomicsTop concepts (fields/topics) attached by OpenAlex
- Cited by
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2Total citation count in OpenAlex
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2025: 2Per-year citation counts (last 5 years)
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56Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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