A 3D micro‐CT assessment of composition and structure of bone tissue after vertical and horizontal alveolar ridge augmentation using CAD /CAM ‐customized titanium mesh
Article Swipe
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· 2024
· Open Access
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· DOI: https://doi.org/10.1111/clr.14342
Objectives To date, no studies have exploited micro‐CT in humans to evaluate bone morphology and structure after bone augmentation with CAD/CAM‐customized titanium mesh, in mandible and maxilla. The aim of this study was to assess the composition and microstructure of bone biopsy through micro‐CT analysis. Materials and Methods Bone augmentation at both maxillary and mandible sites was performed on 30 patients randomly treated with customized mesh, either alone (M−) or covered with resorbable membrane (M+), in both cases filled 50:50 with autogenous bone and xenograft. After 6 months, biopsies were taken and micro‐CT was performed on consecutive 1‐mm‐thick VOIs from coronal to apical side, measuring tissue volumes, trabecular thickness, spacing, and number. Results In both groups, irrespective of membrane use, bone tissue (M−: 29.76% vs. M+: 30.84%) and residual graft material (M−: 14.87% vs. M+: 13.11%) values were similar. Differences were site‐related (maxillary vs. mandibular) with higher percentage of bone tissue and trabecular density of low‐mineralized bone and overall bone in the mandible. Conclusions The composition and structure of bone tissue, as assessed by micro‐CT after alveolar ridge augmentation using CAD/CAM‐customized titanium meshes, showed similar features regardless of whether a collagen membrane was applied.
Related Topics
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1111/clr.14342
- OA Status
- hybrid
- Cited By
- 4
- References
- 30
- Related Works
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- OpenAlex ID
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Raw OpenAlex JSON
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https://openalex.org/W4401380240Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1111/clr.14342Digital Object Identifier
- Title
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A
3D micro‐CT assessment of composition and structure of bone tissue after vertical and horizontal alveolar ridge augmentation usingCAD /CAM ‐customized titanium meshWork title - Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2024Year of publication
- Publication date
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2024-08-06Full publication date if available
- Authors
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Alessandro Cucchi, Gregorio Marchiori, Maria Sartori, Milena Fini, Antonino Fiorino, Raffaele Donati, Giuseppe Corinaldesi, Melania MaglioList of authors in order
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https://doi.org/10.1111/clr.14342Publisher landing page
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YesWhether a free full text is available
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hybridOpen access status per OpenAlex
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https://doi.org/10.1111/clr.14342Direct OA link when available
- Concepts
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Ridge, CAD, Titanium, Composition (language), Chemistry, Geology, Biochemistry, Art, Paleontology, Literature, Organic chemistryTop concepts (fields/topics) attached by OpenAlex
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4Total citation count in OpenAlex
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2025: 4Per-year citation counts (last 5 years)
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30Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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