A256 COMPARING GLOBAL OUTCOMES FOR ENDOSCOPIC SUBMUCOSAL DISSECTION: A SYSTEMATIC REVIEW AND META-ANALYSIS Article Swipe
YOU?
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· 2018
· Open Access
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· DOI: https://doi.org/10.1093/jcag/gwy009.256
BACKGROUND: Endoscopic submucosal dissection (ESD) has become the preferred approach to remove advanced gastrointestinal lesions in Asian countries while widespread adoption in the Western world remains limited. Studies evaluating differences for ESD outcomes between Eastern and Western countries are lacking. AIMS: To provide a comprehensive review on outcomes of ESD between different regions. METHODS: A systematic review and meta-analysis was performed using PubMed, MEDLINE, Web of Science, CINAHL and EBM reviews to identify studies published between 1990 and February 2016. The primary outcome was the efficacy of ESD based on information about either curative resection, en bloc, or R0 resection rates. Secondary outcomes were complication rates, local recurrence rates and procedure times. RESULTS: Overall, 241 publications including 86 388 patients and 91 582 gastrointestinal lesions resected using ESD were identified. 90% of the identified studies reporting ESD on 89 283 lesions were conducted in Eastern countries and 10% of the identified studies reporting ESD outcomes in 2 289 lesions were from Western countries. Meta-analyses showed higher pooled percentage of curative, en bloc, and R0 resection in the Eastern studies; 82% (CI: 81–84), 95% (CI: 94–96) and 89% (CI: 88–91) compared to Western Studies; 71% (CI: 61–79), 85% (CI: 81–89) and 74% (CI: 67–81) respectively. The percentage of perforation requiring surgery was significantly greater in the Western countries (0.49%; CI: 0.09–1.08) compared to Eastern countries (0.02%; CI 0-0,05). ESD procedure times were longer in Western countries (110 vs 77min). CONCLUSIONS: Eastern countries show better ESD outcomes compared to western countries. Availability of local ESD expertise and regional outcomes should be considered for decision making to treat gastrointestinal lesions with ESD. FUNDING AGENCIES: None
Related Topics
- Type
- review
- Language
- en
- Landing Page
- https://doi.org/10.1093/jcag/gwy009.256
- https://academic.oup.com/jcag/article-pdf/1/suppl_2/370/28514724/gwy009.256.pdf
- OA Status
- gold
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W2791324629
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W2791324629Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1093/jcag/gwy009.256Digital Object Identifier
- Title
-
A256 COMPARING GLOBAL OUTCOMES FOR ENDOSCOPIC SUBMUCOSAL DISSECTION: A SYSTEMATIC REVIEW AND META-ANALYSISWork title
- Type
-
reviewOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2018Year of publication
- Publication date
-
2018-02-01Full publication date if available
- Authors
-
Dane Christina Daoud, Nicolas Suter, Madéleine Durand, Mickaël Bouin, B Faulques, Alan Barkun, Daniel von RentelnList of authors in order
- Landing page
-
https://doi.org/10.1093/jcag/gwy009.256Publisher landing page
- PDF URL
-
https://academic.oup.com/jcag/article-pdf/1/suppl_2/370/28514724/gwy009.256.pdfDirect link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
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goldOpen access status per OpenAlex
- OA URL
-
https://academic.oup.com/jcag/article-pdf/1/suppl_2/370/28514724/gwy009.256.pdfDirect OA link when available
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Medicine, Meta-analysis, Endoscopic submucosal dissection, Perforation, Surgery, CINAHL, MEDLINE, Cochrane Library, Internal medicine, Psychological intervention, Metallurgy, Psychiatry, Punching, Law, Materials science, Political scienceTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
0Total citation count in OpenAlex
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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