aac(6’)-Iaq, a novel aminoglycoside acetyltransferase gene identified from an animal isolate Brucella intermedia DW0551 Article Swipe
Naru Lin
,
Wen Xu
,
Da‐Wei Huang
,
Chaoqun Liu
,
Junwan Lu
,
Mei Zhu
,
Qiyu Bao
,
Wei Pan
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.3389/fcimb.2025.1551240
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.3389/fcimb.2025.1551240
Background Bacterial resistance to aminoglycoside antimicrobials is becoming increasingly severe due to their use as commonly prescribed antibiotics. The discovery of new molecular mechanisms of aminoglycoside resistance is critical for the effective treatment of bacterial infections. Methods Bacteria in goose feces were isolated by plate streaking. The identification and characterization of a novel resistance gene from the bacterial genome involved various techniques, including molecular cloning, drug susceptibility testing, protein expression and purification, and enzyme kinetic analysis. Additionally, whole-genome sequencing and phylogenetic studies were performed. Results Brucella intermedia DW0551, isolated from goose feces, was resistant to 35 antibiotics, and the minimum inhibitory concentration (MIC) was particularly high for most aminoglycoside antibiotics. The novel aminoglycoside resistance gene aac(6’)-Iaq encoded by B. intermedia DW0551 conferred resistance to netilmicin, sisomicin, amikacin, kanamycin, gentamicin, tobramycin, and ribostamycin. The amino acid sequence of AAC(6’)-Iaq shared the highest identity (52.63%) with the functionally characterized aminoglycoside acetyltransferase AAC(6’)-If. AAC(6’)-Iaq contained all the conserved sites of the acetyltransferase family NAT_SF. The enzyme exhibited strong affinity and catalytic activity toward netilmicin and sisomicin. The mobile genetic element (MGE) was not found in the flanking regions of the aac(6’)-Iaq and aac(6’)-Iaq -like genes. Conclusion In this work, a novel aminoglycoside acetyltransferase gene, designated aac(6’)-Iaq , which conferred resistance to a variety of aminoglycoside antimicrobials, was identified in an animal Brucella intermedia isolate. Identification of new antibiotic resistance mechanisms in bacteria isolated from animals could aid in the treatment of animal and human infectious diseases caused by related bacterial species.
Related Topics
Concepts
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.3389/fcimb.2025.1551240
- https://www.frontiersin.org/journals/cellular-and-infection-microbiology/articles/10.3389/fcimb.2025.1551240/pdf
- OA Status
- gold
- Cited By
- 2
- References
- 50
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4408314541
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4408314541Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.3389/fcimb.2025.1551240Digital Object Identifier
- Title
-
aac(6’)-Iaq, a novel aminoglycoside acetyltransferase gene identified from an animal isolate Brucella intermedia DW0551Work title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2025Year of publication
- Publication date
-
2025-03-11Full publication date if available
- Authors
-
Naru Lin, Wen Xu, Da‐Wei Huang, Chaoqun Liu, Junwan Lu, Mei Zhu, Qiyu Bao, Wei PanList of authors in order
- Landing page
-
https://doi.org/10.3389/fcimb.2025.1551240Publisher landing page
- PDF URL
-
https://www.frontiersin.org/journals/cellular-and-infection-microbiology/articles/10.3389/fcimb.2025.1551240/pdfDirect link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
-
https://www.frontiersin.org/journals/cellular-and-infection-microbiology/articles/10.3389/fcimb.2025.1551240/pdfDirect OA link when available
- Concepts
-
Sisomicin, Microbiology, Aminoglycoside, Netilmicin, Biology, Gentamicin, Antibiotics, TobramycinTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
2Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 2Per-year citation counts (last 5 years)
- References (count)
-
50Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W4408314541 |
|---|---|
| doi | https://doi.org/10.3389/fcimb.2025.1551240 |
| ids.doi | https://doi.org/10.3389/fcimb.2025.1551240 |
| ids.pmid | https://pubmed.ncbi.nlm.nih.gov/40134786 |
| ids.openalex | https://openalex.org/W4408314541 |
| fwci | 4.26932672 |
| mesh[0].qualifier_ui | |
| mesh[0].descriptor_ui | D000818 |
| mesh[0].is_major_topic | False |
| mesh[0].qualifier_name | |
| mesh[0].descriptor_name | Animals |
| mesh[1].qualifier_ui | Q000235 |
| mesh[1].descriptor_ui | D000123 |
| mesh[1].is_major_topic | True |
| mesh[1].qualifier_name | genetics |
| mesh[1].descriptor_name | Acetyltransferases |
| mesh[2].qualifier_ui | Q000378 |
| mesh[2].descriptor_ui | D000123 |
| mesh[2].is_major_topic | True |
| mesh[2].qualifier_name | metabolism |
| mesh[2].descriptor_name | Acetyltransferases |
| mesh[3].qualifier_ui | |
| mesh[3].descriptor_ui | D008826 |
| mesh[3].is_major_topic | True |
| mesh[3].qualifier_name | |
| mesh[3].descriptor_name | Microbial Sensitivity Tests |
| mesh[4].qualifier_ui | Q000494 |
| mesh[4].descriptor_ui | D000900 |
| mesh[4].is_major_topic | True |
| mesh[4].qualifier_name | pharmacology |
| mesh[4].descriptor_name | Anti-Bacterial Agents |
| mesh[5].qualifier_ui | |
| mesh[5].descriptor_ui | D010802 |
| mesh[5].is_major_topic | True |
| mesh[5].qualifier_name | |
| mesh[5].descriptor_name | Phylogeny |
| mesh[6].qualifier_ui | Q000494 |
| mesh[6].descriptor_ui | D000617 |
| mesh[6].is_major_topic | True |
| mesh[6].qualifier_name | pharmacology |
| mesh[6].descriptor_name | Aminoglycosides |
| mesh[7].qualifier_ui | |
| mesh[7].descriptor_ui | D000073336 |
| mesh[7].is_major_topic | True |
| mesh[7].qualifier_name | |
| mesh[7].descriptor_name | Whole Genome Sequencing |
| mesh[8].qualifier_ui | Q000382 |
| mesh[8].descriptor_ui | D005243 |
| mesh[8].is_major_topic | False |
| mesh[8].qualifier_name | microbiology |
| mesh[8].descriptor_name | Feces |
| mesh[9].qualifier_ui | Q000235 |
| mesh[9].descriptor_ui | D024881 |
| mesh[9].is_major_topic | False |
| mesh[9].qualifier_name | genetics |
| mesh[9].descriptor_name | Drug Resistance, Bacterial |
| mesh[10].qualifier_ui | |
| mesh[10].descriptor_ui | D003001 |
| mesh[10].is_major_topic | False |
| mesh[10].qualifier_name | |
| mesh[10].descriptor_name | Cloning, Molecular |
| mesh[11].qualifier_ui | Q000382 |
| mesh[11].descriptor_ui | D002006 |
| mesh[11].is_major_topic | False |
| mesh[11].qualifier_name | microbiology |
| mesh[11].descriptor_name | Brucellosis |
| mesh[12].qualifier_ui | Q000662 |
| mesh[12].descriptor_ui | D002006 |
| mesh[12].is_major_topic | False |
| mesh[12].qualifier_name | veterinary |
| mesh[12].descriptor_name | Brucellosis |
| mesh[13].qualifier_ui | Q000235 |
| mesh[13].descriptor_ui | D024901 |
| mesh[13].is_major_topic | False |
| mesh[13].qualifier_name | genetics |
| mesh[13].descriptor_name | Drug Resistance, Multiple, Bacterial |
| mesh[14].qualifier_ui | |
| mesh[14].descriptor_ui | D016680 |
| mesh[14].is_major_topic | False |
| mesh[14].qualifier_name | |
| mesh[14].descriptor_name | Genome, Bacterial |
| mesh[15].qualifier_ui | |
| mesh[15].descriptor_ui | D000818 |
| mesh[15].is_major_topic | False |
| mesh[15].qualifier_name | |
| mesh[15].descriptor_name | Animals |
| mesh[16].qualifier_ui | Q000235 |
| mesh[16].descriptor_ui | D000123 |
| mesh[16].is_major_topic | True |
| mesh[16].qualifier_name | genetics |
| mesh[16].descriptor_name | Acetyltransferases |
| mesh[17].qualifier_ui | Q000378 |
| mesh[17].descriptor_ui | D000123 |
| mesh[17].is_major_topic | True |
| mesh[17].qualifier_name | metabolism |
| mesh[17].descriptor_name | Acetyltransferases |
| mesh[18].qualifier_ui | |
| mesh[18].descriptor_ui | D008826 |
| mesh[18].is_major_topic | True |
| mesh[18].qualifier_name | |
| mesh[18].descriptor_name | Microbial Sensitivity Tests |
| mesh[19].qualifier_ui | Q000494 |
| mesh[19].descriptor_ui | D000900 |
| mesh[19].is_major_topic | True |
| mesh[19].qualifier_name | pharmacology |
| mesh[19].descriptor_name | Anti-Bacterial Agents |
| mesh[20].qualifier_ui | |
| mesh[20].descriptor_ui | D010802 |
| mesh[20].is_major_topic | True |
| mesh[20].qualifier_name | |
| mesh[20].descriptor_name | Phylogeny |
| mesh[21].qualifier_ui | Q000494 |
| mesh[21].descriptor_ui | D000617 |
| mesh[21].is_major_topic | True |
| mesh[21].qualifier_name | pharmacology |
| mesh[21].descriptor_name | Aminoglycosides |
| mesh[22].qualifier_ui | |
| mesh[22].descriptor_ui | D000073336 |
| mesh[22].is_major_topic | True |
| mesh[22].qualifier_name | |
| mesh[22].descriptor_name | Whole Genome Sequencing |
| mesh[23].qualifier_ui | Q000382 |
| mesh[23].descriptor_ui | D005243 |
| mesh[23].is_major_topic | False |
| mesh[23].qualifier_name | microbiology |
| mesh[23].descriptor_name | Feces |
| mesh[24].qualifier_ui | Q000235 |
| mesh[24].descriptor_ui | D024881 |
| mesh[24].is_major_topic | False |
| mesh[24].qualifier_name | genetics |
| mesh[24].descriptor_name | Drug Resistance, Bacterial |
| mesh[25].qualifier_ui | |
| mesh[25].descriptor_ui | D003001 |
| mesh[25].is_major_topic | False |
| mesh[25].qualifier_name | |
| mesh[25].descriptor_name | Cloning, Molecular |
| mesh[26].qualifier_ui | Q000382 |
| mesh[26].descriptor_ui | D002006 |
| mesh[26].is_major_topic | False |
| mesh[26].qualifier_name | microbiology |
| mesh[26].descriptor_name | Brucellosis |
| mesh[27].qualifier_ui | Q000662 |
| mesh[27].descriptor_ui | D002006 |
| mesh[27].is_major_topic | False |
| mesh[27].qualifier_name | veterinary |
| mesh[27].descriptor_name | Brucellosis |
| mesh[28].qualifier_ui | Q000235 |
| mesh[28].descriptor_ui | D024901 |
| mesh[28].is_major_topic | False |
| mesh[28].qualifier_name | genetics |
| mesh[28].descriptor_name | Drug Resistance, Multiple, Bacterial |
| mesh[29].qualifier_ui | |
| mesh[29].descriptor_ui | D016680 |
| mesh[29].is_major_topic | False |
| mesh[29].qualifier_name | |
| mesh[29].descriptor_name | Genome, Bacterial |
| mesh[30].qualifier_ui | Q000235 |
| mesh[30].descriptor_ui | D000123 |
| mesh[30].is_major_topic | True |
| mesh[30].qualifier_name | genetics |
| mesh[30].descriptor_name | Acetyltransferases |
| mesh[31].qualifier_ui | Q000378 |
| mesh[31].descriptor_ui | D000123 |
| mesh[31].is_major_topic | True |
| mesh[31].qualifier_name | metabolism |
| mesh[31].descriptor_name | Acetyltransferases |
| mesh[32].qualifier_ui | |
| mesh[32].descriptor_ui | D000818 |
| mesh[32].is_major_topic | False |
| mesh[32].qualifier_name | |
| mesh[32].descriptor_name | Animals |
| mesh[33].qualifier_ui | Q000494 |
| mesh[33].descriptor_ui | D000900 |
| mesh[33].is_major_topic | False |
| mesh[33].qualifier_name | pharmacology |
| mesh[33].descriptor_name | Anti-Bacterial Agents |
| mesh[34].qualifier_ui | |
| mesh[34].descriptor_ui | D008826 |
| mesh[34].is_major_topic | False |
| mesh[34].qualifier_name | |
| mesh[34].descriptor_name | Microbial Sensitivity Tests |
| mesh[35].qualifier_ui | Q000494 |
| mesh[35].descriptor_ui | D000617 |
| mesh[35].is_major_topic | False |
| mesh[35].qualifier_name | pharmacology |
| mesh[35].descriptor_name | Aminoglycosides |
| mesh[36].qualifier_ui | |
| mesh[36].descriptor_ui | D010802 |
| mesh[36].is_major_topic | False |
| mesh[36].qualifier_name | |
| mesh[36].descriptor_name | Phylogeny |
| mesh[37].qualifier_ui | Q000382 |
| mesh[37].descriptor_ui | D005243 |
| mesh[37].is_major_topic | False |
| mesh[37].qualifier_name | microbiology |
| mesh[37].descriptor_name | Feces |
| mesh[38].qualifier_ui | Q000382 |
| mesh[38].descriptor_ui | D005777 |
| mesh[38].is_major_topic | False |
| mesh[38].qualifier_name | microbiology |
| mesh[38].descriptor_name | Geese |
| mesh[39].qualifier_ui | |
| mesh[39].descriptor_ui | D000073336 |
| mesh[39].is_major_topic | False |
| mesh[39].qualifier_name | |
| mesh[39].descriptor_name | Whole Genome Sequencing |
| mesh[40].qualifier_ui | Q000235 |
| mesh[40].descriptor_ui | D024881 |
| mesh[40].is_major_topic | False |
| mesh[40].qualifier_name | genetics |
| mesh[40].descriptor_name | Drug Resistance, Bacterial |
| mesh[41].qualifier_ui | |
| mesh[41].descriptor_ui | D016680 |
| mesh[41].is_major_topic | False |
| mesh[41].qualifier_name | |
| mesh[41].descriptor_name | Genome, Bacterial |
| mesh[42].qualifier_ui | Q000382 |
| mesh[42].descriptor_ui | D002006 |
| mesh[42].is_major_topic | True |
| mesh[42].qualifier_name | microbiology |
| mesh[42].descriptor_name | Brucellosis |
| mesh[43].qualifier_ui | Q000662 |
| mesh[43].descriptor_ui | D002006 |
| mesh[43].is_major_topic | True |
| mesh[43].qualifier_name | veterinary |
| mesh[43].descriptor_name | Brucellosis |
| mesh[44].qualifier_ui | |
| mesh[44].descriptor_ui | D003001 |
| mesh[44].is_major_topic | False |
| mesh[44].qualifier_name | |
| mesh[44].descriptor_name | Cloning, Molecular |
| type | article |
| title | aac(6’)-Iaq, a novel aminoglycoside acetyltransferase gene identified from an animal isolate Brucella intermedia DW0551 |
| biblio.issue | |
| biblio.volume | 15 |
| biblio.last_page | 1551240 |
| biblio.first_page | 1551240 |
| topics[0].id | https://openalex.org/T10147 |
| topics[0].field.id | https://openalex.org/fields/13 |
| topics[0].field.display_name | Biochemistry, Genetics and Molecular Biology |
| topics[0].score | 0.9993000030517578 |
| topics[0].domain.id | https://openalex.org/domains/1 |
| topics[0].domain.display_name | Life Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/1313 |
| topics[0].subfield.display_name | Molecular Medicine |
| topics[0].display_name | Antibiotic Resistance in Bacteria |
| topics[1].id | https://openalex.org/T11048 |
| topics[1].field.id | https://openalex.org/fields/23 |
| topics[1].field.display_name | Environmental Science |
| topics[1].score | 0.9965000152587891 |
| topics[1].domain.id | https://openalex.org/domains/3 |
| topics[1].domain.display_name | Physical Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/2303 |
| topics[1].subfield.display_name | Ecology |
| topics[1].display_name | Bacteriophages and microbial interactions |
| topics[2].id | https://openalex.org/T10521 |
| topics[2].field.id | https://openalex.org/fields/13 |
| topics[2].field.display_name | Biochemistry, Genetics and Molecular Biology |
| topics[2].score | 0.9952999949455261 |
| topics[2].domain.id | https://openalex.org/domains/1 |
| topics[2].domain.display_name | Life Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/1312 |
| topics[2].subfield.display_name | Molecular Biology |
| topics[2].display_name | RNA and protein synthesis mechanisms |
| is_xpac | False |
| apc_list.value | 2950 |
| apc_list.currency | USD |
| apc_list.value_usd | 2950 |
| apc_paid.value | 2950 |
| apc_paid.currency | USD |
| apc_paid.value_usd | 2950 |
| concepts[0].id | https://openalex.org/C2780346086 |
| concepts[0].level | 5 |
| concepts[0].score | 0.7020087838172913 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q3962119 |
| concepts[0].display_name | Sisomicin |
| concepts[1].id | https://openalex.org/C89423630 |
| concepts[1].level | 1 |
| concepts[1].score | 0.6796948909759521 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q7193 |
| concepts[1].display_name | Microbiology |
| concepts[2].id | https://openalex.org/C2777787772 |
| concepts[2].level | 3 |
| concepts[2].score | 0.6305363178253174 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q45355603 |
| concepts[2].display_name | Aminoglycoside |
| concepts[3].id | https://openalex.org/C2778977604 |
| concepts[3].level | 5 |
| concepts[3].score | 0.6015709042549133 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q2553496 |
| concepts[3].display_name | Netilmicin |
| concepts[4].id | https://openalex.org/C86803240 |
| concepts[4].level | 0 |
| concepts[4].score | 0.5485806465148926 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q420 |
| concepts[4].display_name | Biology |
| concepts[5].id | https://openalex.org/C2775832221 |
| concepts[5].level | 3 |
| concepts[5].score | 0.3662295341491699 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q422482 |
| concepts[5].display_name | Gentamicin |
| concepts[6].id | https://openalex.org/C501593827 |
| concepts[6].level | 2 |
| concepts[6].score | 0.23947909474372864 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q12187 |
| concepts[6].display_name | Antibiotics |
| concepts[7].id | https://openalex.org/C2778974779 |
| concepts[7].level | 4 |
| concepts[7].score | 0.2332211434841156 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q1758380 |
| concepts[7].display_name | Tobramycin |
| keywords[0].id | https://openalex.org/keywords/sisomicin |
| keywords[0].score | 0.7020087838172913 |
| keywords[0].display_name | Sisomicin |
| keywords[1].id | https://openalex.org/keywords/microbiology |
| keywords[1].score | 0.6796948909759521 |
| keywords[1].display_name | Microbiology |
| keywords[2].id | https://openalex.org/keywords/aminoglycoside |
| keywords[2].score | 0.6305363178253174 |
| keywords[2].display_name | Aminoglycoside |
| keywords[3].id | https://openalex.org/keywords/netilmicin |
| keywords[3].score | 0.6015709042549133 |
| keywords[3].display_name | Netilmicin |
| keywords[4].id | https://openalex.org/keywords/biology |
| keywords[4].score | 0.5485806465148926 |
| keywords[4].display_name | Biology |
| keywords[5].id | https://openalex.org/keywords/gentamicin |
| keywords[5].score | 0.3662295341491699 |
| keywords[5].display_name | Gentamicin |
| keywords[6].id | https://openalex.org/keywords/antibiotics |
| keywords[6].score | 0.23947909474372864 |
| keywords[6].display_name | Antibiotics |
| keywords[7].id | https://openalex.org/keywords/tobramycin |
| keywords[7].score | 0.2332211434841156 |
| keywords[7].display_name | Tobramycin |
| language | en |
| locations[0].id | doi:10.3389/fcimb.2025.1551240 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S2506667490 |
| locations[0].source.issn | 2235-2988 |
| locations[0].source.type | journal |
| locations[0].source.is_oa | True |
| locations[0].source.issn_l | 2235-2988 |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | True |
| locations[0].source.display_name | Frontiers in Cellular and Infection Microbiology |
| locations[0].source.host_organization | https://openalex.org/P4310320527 |
| locations[0].source.host_organization_name | Frontiers Media |
| locations[0].source.host_organization_lineage | https://openalex.org/P4310320527 |
| locations[0].source.host_organization_lineage_names | Frontiers Media |
| locations[0].license | cc-by |
| locations[0].pdf_url | https://www.frontiersin.org/journals/cellular-and-infection-microbiology/articles/10.3389/fcimb.2025.1551240/pdf |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | https://openalex.org/licenses/cc-by |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | Frontiers in Cellular and Infection Microbiology |
| locations[0].landing_page_url | https://doi.org/10.3389/fcimb.2025.1551240 |
| locations[1].id | pmid:40134786 |
| locations[1].is_oa | False |
| locations[1].source.id | https://openalex.org/S4306525036 |
| locations[1].source.issn | |
| locations[1].source.type | repository |
| locations[1].source.is_oa | False |
| locations[1].source.issn_l | |
| locations[1].source.is_core | False |
| locations[1].source.is_in_doaj | False |
| locations[1].source.display_name | PubMed |
| locations[1].source.host_organization | https://openalex.org/I1299303238 |
| locations[1].source.host_organization_name | National Institutes of Health |
| locations[1].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[1].license | |
| locations[1].pdf_url | |
| locations[1].version | publishedVersion |
| locations[1].raw_type | |
| locations[1].license_id | |
| locations[1].is_accepted | True |
| locations[1].is_published | True |
| locations[1].raw_source_name | Frontiers in cellular and infection microbiology |
| locations[1].landing_page_url | https://pubmed.ncbi.nlm.nih.gov/40134786 |
| locations[2].id | pmh:oai:doaj.org/article:bb1378dc76b646b1bca67ad0592cefbd |
| locations[2].is_oa | False |
| locations[2].source.id | https://openalex.org/S4306401280 |
| locations[2].source.issn | |
| locations[2].source.type | repository |
| locations[2].source.is_oa | False |
| locations[2].source.issn_l | |
| locations[2].source.is_core | False |
| locations[2].source.is_in_doaj | False |
| locations[2].source.display_name | DOAJ (DOAJ: Directory of Open Access Journals) |
| locations[2].source.host_organization | |
| locations[2].source.host_organization_name | |
| locations[2].license | |
| locations[2].pdf_url | |
| locations[2].version | submittedVersion |
| locations[2].raw_type | article |
| locations[2].license_id | |
| locations[2].is_accepted | False |
| locations[2].is_published | False |
| locations[2].raw_source_name | Frontiers in Cellular and Infection Microbiology, Vol 15 (2025) |
| locations[2].landing_page_url | https://doaj.org/article/bb1378dc76b646b1bca67ad0592cefbd |
| locations[3].id | pmh:oai:pubmedcentral.nih.gov:11932996 |
| locations[3].is_oa | True |
| locations[3].source.id | https://openalex.org/S2764455111 |
| locations[3].source.issn | |
| locations[3].source.type | repository |
| locations[3].source.is_oa | False |
| locations[3].source.issn_l | |
| locations[3].source.is_core | False |
| locations[3].source.is_in_doaj | False |
| locations[3].source.display_name | PubMed Central |
| locations[3].source.host_organization | https://openalex.org/I1299303238 |
| locations[3].source.host_organization_name | National Institutes of Health |
| locations[3].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[3].license | other-oa |
| locations[3].pdf_url | |
| locations[3].version | submittedVersion |
| locations[3].raw_type | Text |
| locations[3].license_id | https://openalex.org/licenses/other-oa |
| locations[3].is_accepted | False |
| locations[3].is_published | False |
| locations[3].raw_source_name | Front Cell Infect Microbiol |
| locations[3].landing_page_url | https://www.ncbi.nlm.nih.gov/pmc/articles/11932996 |
| indexed_in | crossref, doaj, pubmed |
| authorships[0].author.id | https://openalex.org/A5112231847 |
| authorships[0].author.orcid | |
| authorships[0].author.display_name | Naru Lin |
| authorships[0].countries | CN |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I27781120 |
| authorships[0].affiliations[0].raw_affiliation_string | Key Laboratory of Medical Genetics of Zhejiang Province, Key Laboratory of Laboratory Medicine, Ministry of Education, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, China |
| authorships[0].affiliations[1].raw_affiliation_string | Division of Tuberculosis Control and Prevention, Fujian Provincial Center for Disease Control and Prevention, Fuzhou, China |
| authorships[0].institutions[0].id | https://openalex.org/I27781120 |
| authorships[0].institutions[0].ror | https://ror.org/00rd5t069 |
| authorships[0].institutions[0].type | education |
| authorships[0].institutions[0].lineage | https://openalex.org/I27781120 |
| authorships[0].institutions[0].country_code | CN |
| authorships[0].institutions[0].display_name | Wenzhou Medical University |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Naru Lin |
| authorships[0].is_corresponding | False |
| authorships[0].raw_affiliation_strings | Division of Tuberculosis Control and Prevention, Fujian Provincial Center for Disease Control and Prevention, Fuzhou, China, Key Laboratory of Medical Genetics of Zhejiang Province, Key Laboratory of Laboratory Medicine, Ministry of Education, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, China |
| authorships[1].author.id | https://openalex.org/A5101964488 |
| authorships[1].author.orcid | https://orcid.org/0009-0007-0759-5974 |
| authorships[1].author.display_name | Wen Xu |
| authorships[1].affiliations[0].raw_affiliation_string | Department of Rehabilitation Medicine, Army 73rd Group Military Hospital, Xiamen, China |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Wanna Xu |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | Department of Rehabilitation Medicine, Army 73rd Group Military Hospital, Xiamen, China |
| authorships[2].author.id | https://openalex.org/A5039070819 |
| authorships[2].author.orcid | https://orcid.org/0000-0003-4355-7047 |
| authorships[2].author.display_name | Da‐Wei Huang |
| authorships[2].countries | CN |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I4210165678 |
| authorships[2].affiliations[0].raw_affiliation_string | Department of Clinical Laboratory, the People's Hospital of Yuhuan, Taizhou, Zhejiang, China |
| authorships[2].institutions[0].id | https://openalex.org/I4210165678 |
| authorships[2].institutions[0].ror | https://ror.org/039401462 |
| authorships[2].institutions[0].type | healthcare |
| authorships[2].institutions[0].lineage | https://openalex.org/I4210165678 |
| authorships[2].institutions[0].country_code | CN |
| authorships[2].institutions[0].display_name | Yuxian People's Hospital |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Dawei Huang |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | Department of Clinical Laboratory, the People's Hospital of Yuhuan, Taizhou, Zhejiang, China |
| authorships[3].author.id | https://openalex.org/A5102973309 |
| authorships[3].author.orcid | https://orcid.org/0000-0001-8090-1033 |
| authorships[3].author.display_name | Chaoqun Liu |
| authorships[3].countries | CN |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I4210152737 |
| authorships[3].affiliations[0].raw_affiliation_string | Medical Molecular Biology Laboratory, School of Medicine, Jinhua Polytechnic, Jinhua, China |
| authorships[3].institutions[0].id | https://openalex.org/I4210152737 |
| authorships[3].institutions[0].ror | https://ror.org/047hbb113 |
| authorships[3].institutions[0].type | education |
| authorships[3].institutions[0].lineage | https://openalex.org/I4210152737 |
| authorships[3].institutions[0].country_code | CN |
| authorships[3].institutions[0].display_name | Jinhua Polytechnic |
| authorships[3].author_position | middle |
| authorships[3].raw_author_name | Chaoqun Liu |
| authorships[3].is_corresponding | False |
| authorships[3].raw_affiliation_strings | Medical Molecular Biology Laboratory, School of Medicine, Jinhua Polytechnic, Jinhua, China |
| authorships[4].author.id | https://openalex.org/A5102016185 |
| authorships[4].author.orcid | https://orcid.org/0000-0002-7378-6783 |
| authorships[4].author.display_name | Junwan Lu |
| authorships[4].countries | CN |
| authorships[4].affiliations[0].institution_ids | https://openalex.org/I4210152737 |
| authorships[4].affiliations[0].raw_affiliation_string | Medical Molecular Biology Laboratory, School of Medicine, Jinhua Polytechnic, Jinhua, China |
| authorships[4].institutions[0].id | https://openalex.org/I4210152737 |
| authorships[4].institutions[0].ror | https://ror.org/047hbb113 |
| authorships[4].institutions[0].type | education |
| authorships[4].institutions[0].lineage | https://openalex.org/I4210152737 |
| authorships[4].institutions[0].country_code | CN |
| authorships[4].institutions[0].display_name | Jinhua Polytechnic |
| authorships[4].author_position | middle |
| authorships[4].raw_author_name | Junwan Lu |
| authorships[4].is_corresponding | False |
| authorships[4].raw_affiliation_strings | Medical Molecular Biology Laboratory, School of Medicine, Jinhua Polytechnic, Jinhua, China |
| authorships[5].author.id | https://openalex.org/A5101464152 |
| authorships[5].author.orcid | https://orcid.org/0000-0003-3625-8794 |
| authorships[5].author.display_name | Mei Zhu |
| authorships[5].countries | CN |
| authorships[5].affiliations[0].institution_ids | https://openalex.org/I4210119853 |
| authorships[5].affiliations[0].raw_affiliation_string | Department of Clinical Laboratory, Zhejiang Hospital, Hangzhou, China |
| authorships[5].institutions[0].id | https://openalex.org/I4210119853 |
| authorships[5].institutions[0].ror | https://ror.org/02kzr5g33 |
| authorships[5].institutions[0].type | healthcare |
| authorships[5].institutions[0].lineage | https://openalex.org/I4210119853 |
| authorships[5].institutions[0].country_code | CN |
| authorships[5].institutions[0].display_name | Zhejiang Hospital |
| authorships[5].author_position | middle |
| authorships[5].raw_author_name | Mei Zhu |
| authorships[5].is_corresponding | True |
| authorships[5].raw_affiliation_strings | Department of Clinical Laboratory, Zhejiang Hospital, Hangzhou, China |
| authorships[6].author.id | https://openalex.org/A5101943568 |
| authorships[6].author.orcid | https://orcid.org/0000-0001-6523-8763 |
| authorships[6].author.display_name | Qiyu Bao |
| authorships[6].countries | CN |
| authorships[6].affiliations[0].institution_ids | https://openalex.org/I4210152737 |
| authorships[6].affiliations[0].raw_affiliation_string | Medical Molecular Biology Laboratory, School of Medicine, Jinhua Polytechnic, Jinhua, China |
| authorships[6].affiliations[1].institution_ids | https://openalex.org/I27781120 |
| authorships[6].affiliations[1].raw_affiliation_string | Key Laboratory of Medical Genetics of Zhejiang Province, Key Laboratory of Laboratory Medicine, Ministry of Education, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, China |
| authorships[6].institutions[0].id | https://openalex.org/I4210152737 |
| authorships[6].institutions[0].ror | https://ror.org/047hbb113 |
| authorships[6].institutions[0].type | education |
| authorships[6].institutions[0].lineage | https://openalex.org/I4210152737 |
| authorships[6].institutions[0].country_code | CN |
| authorships[6].institutions[0].display_name | Jinhua Polytechnic |
| authorships[6].institutions[1].id | https://openalex.org/I27781120 |
| authorships[6].institutions[1].ror | https://ror.org/00rd5t069 |
| authorships[6].institutions[1].type | education |
| authorships[6].institutions[1].lineage | https://openalex.org/I27781120 |
| authorships[6].institutions[1].country_code | CN |
| authorships[6].institutions[1].display_name | Wenzhou Medical University |
| authorships[6].author_position | middle |
| authorships[6].raw_author_name | Qiyu Bao |
| authorships[6].is_corresponding | True |
| authorships[6].raw_affiliation_strings | Key Laboratory of Medical Genetics of Zhejiang Province, Key Laboratory of Laboratory Medicine, Ministry of Education, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, China, Medical Molecular Biology Laboratory, School of Medicine, Jinhua Polytechnic, Jinhua, China |
| authorships[7].author.id | https://openalex.org/A5112120357 |
| authorships[7].author.orcid | https://orcid.org/0000-0001-8733-0683 |
| authorships[7].author.display_name | Wei Pan |
| authorships[7].countries | CN |
| authorships[7].affiliations[0].institution_ids | https://openalex.org/I4210165678 |
| authorships[7].affiliations[0].raw_affiliation_string | Department of Clinical Laboratory, the People's Hospital of Yuhuan, Taizhou, Zhejiang, China |
| authorships[7].institutions[0].id | https://openalex.org/I4210165678 |
| authorships[7].institutions[0].ror | https://ror.org/039401462 |
| authorships[7].institutions[0].type | healthcare |
| authorships[7].institutions[0].lineage | https://openalex.org/I4210165678 |
| authorships[7].institutions[0].country_code | CN |
| authorships[7].institutions[0].display_name | Yuxian People's Hospital |
| authorships[7].author_position | last |
| authorships[7].raw_author_name | Wei Pan |
| authorships[7].is_corresponding | True |
| authorships[7].raw_affiliation_strings | Department of Clinical Laboratory, the People's Hospital of Yuhuan, Taizhou, Zhejiang, China |
| has_content.pdf | True |
| has_content.grobid_xml | False |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://www.frontiersin.org/journals/cellular-and-infection-microbiology/articles/10.3389/fcimb.2025.1551240/pdf |
| open_access.oa_status | gold |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | aac(6’)-Iaq, a novel aminoglycoside acetyltransferase gene identified from an animal isolate Brucella intermedia DW0551 |
| has_fulltext | False |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T10147 |
| primary_topic.field.id | https://openalex.org/fields/13 |
| primary_topic.field.display_name | Biochemistry, Genetics and Molecular Biology |
| primary_topic.score | 0.9993000030517578 |
| primary_topic.domain.id | https://openalex.org/domains/1 |
| primary_topic.domain.display_name | Life Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/1313 |
| primary_topic.subfield.display_name | Molecular Medicine |
| primary_topic.display_name | Antibiotic Resistance in Bacteria |
| related_works | https://openalex.org/W1978878092, https://openalex.org/W2388151007, https://openalex.org/W2423719353, https://openalex.org/W2030006830, https://openalex.org/W2079729757, https://openalex.org/W1965197763, https://openalex.org/W2098041361, https://openalex.org/W1991892012, https://openalex.org/W2183819412, https://openalex.org/W2096316950 |
| cited_by_count | 2 |
| counts_by_year[0].year | 2025 |
| counts_by_year[0].cited_by_count | 2 |
| locations_count | 4 |
| best_oa_location.id | doi:10.3389/fcimb.2025.1551240 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S2506667490 |
| best_oa_location.source.issn | 2235-2988 |
| best_oa_location.source.type | journal |
| best_oa_location.source.is_oa | True |
| best_oa_location.source.issn_l | 2235-2988 |
| best_oa_location.source.is_core | True |
| best_oa_location.source.is_in_doaj | True |
| best_oa_location.source.display_name | Frontiers in Cellular and Infection Microbiology |
| best_oa_location.source.host_organization | https://openalex.org/P4310320527 |
| best_oa_location.source.host_organization_name | Frontiers Media |
| best_oa_location.source.host_organization_lineage | https://openalex.org/P4310320527 |
| best_oa_location.source.host_organization_lineage_names | Frontiers Media |
| best_oa_location.license | cc-by |
| best_oa_location.pdf_url | https://www.frontiersin.org/journals/cellular-and-infection-microbiology/articles/10.3389/fcimb.2025.1551240/pdf |
| best_oa_location.version | publishedVersion |
| best_oa_location.raw_type | journal-article |
| best_oa_location.license_id | https://openalex.org/licenses/cc-by |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | True |
| best_oa_location.raw_source_name | Frontiers in Cellular and Infection Microbiology |
| best_oa_location.landing_page_url | https://doi.org/10.3389/fcimb.2025.1551240 |
| primary_location.id | doi:10.3389/fcimb.2025.1551240 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S2506667490 |
| primary_location.source.issn | 2235-2988 |
| primary_location.source.type | journal |
| primary_location.source.is_oa | True |
| primary_location.source.issn_l | 2235-2988 |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | True |
| primary_location.source.display_name | Frontiers in Cellular and Infection Microbiology |
| primary_location.source.host_organization | https://openalex.org/P4310320527 |
| primary_location.source.host_organization_name | Frontiers Media |
| primary_location.source.host_organization_lineage | https://openalex.org/P4310320527 |
| primary_location.source.host_organization_lineage_names | Frontiers Media |
| primary_location.license | cc-by |
| primary_location.pdf_url | https://www.frontiersin.org/journals/cellular-and-infection-microbiology/articles/10.3389/fcimb.2025.1551240/pdf |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | https://openalex.org/licenses/cc-by |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | Frontiers in Cellular and Infection Microbiology |
| primary_location.landing_page_url | https://doi.org/10.3389/fcimb.2025.1551240 |
| publication_date | 2025-03-11 |
| publication_year | 2025 |
| referenced_works | https://openalex.org/W3022327571, https://openalex.org/W4306871314, https://openalex.org/W2982531601, https://openalex.org/W2137152524, https://openalex.org/W2531670570, https://openalex.org/W3048398081, https://openalex.org/W3143063265, https://openalex.org/W2162404814, https://openalex.org/W2593928319, https://openalex.org/W2084494110, https://openalex.org/W2158084007, https://openalex.org/W3121652846, https://openalex.org/W2107772251, https://openalex.org/W2105240505, https://openalex.org/W2403187819, https://openalex.org/W2148346381, https://openalex.org/W3201783297, https://openalex.org/W2012784594, https://openalex.org/W3157538126, https://openalex.org/W2160378127, https://openalex.org/W2014003966, https://openalex.org/W2161533999, https://openalex.org/W2134375163, https://openalex.org/W2912635722, https://openalex.org/W3183316203, https://openalex.org/W2122420378, https://openalex.org/W2039204060, https://openalex.org/W2559191318, https://openalex.org/W2004589024, https://openalex.org/W2060989808, https://openalex.org/W2086223988, https://openalex.org/W2119888547, https://openalex.org/W2978981800, https://openalex.org/W1825285599, https://openalex.org/W3101950313, https://openalex.org/W2126472922, https://openalex.org/W2114570899, https://openalex.org/W2096093282, https://openalex.org/W2155383660, https://openalex.org/W1963631541, https://openalex.org/W4364353197, https://openalex.org/W2894808609, https://openalex.org/W1190355396, https://openalex.org/W2135697426, https://openalex.org/W1983946633, https://openalex.org/W1982855075, https://openalex.org/W2952167528, https://openalex.org/W2046757176, https://openalex.org/W4387742136, https://openalex.org/W3088417057 |
| referenced_works_count | 50 |
| abstract_inverted_index., | 203 |
| abstract_inverted_index.a | 51, 196, 208 |
| abstract_inverted_index.35 | 95 |
| abstract_inverted_index.B. | 118 |
| abstract_inverted_index.In | 193 |
| abstract_inverted_index.an | 216 |
| abstract_inverted_index.as | 14 |
| abstract_inverted_index.by | 43, 117, 244 |
| abstract_inverted_index.in | 38, 181, 215, 227, 234 |
| abstract_inverted_index.is | 6, 27 |
| abstract_inverted_index.of | 20, 24, 33, 50, 136, 156, 185, 210, 222, 237 |
| abstract_inverted_index.to | 3, 11, 94, 123, 207 |
| abstract_inverted_index.The | 18, 46, 110, 132, 161, 173 |
| abstract_inverted_index.aid | 233 |
| abstract_inverted_index.all | 152 |
| abstract_inverted_index.and | 48, 70, 72, 79, 97, 130, 166, 171, 188, 239 |
| abstract_inverted_index.due | 10 |
| abstract_inverted_index.for | 29, 106 |
| abstract_inverted_index.new | 21, 223 |
| abstract_inverted_index.not | 179 |
| abstract_inverted_index.the | 30, 56, 98, 139, 144, 153, 157, 182, 186, 235 |
| abstract_inverted_index.use | 13 |
| abstract_inverted_index.was | 92, 103, 178, 213 |
| abstract_inverted_index.acid | 134 |
| abstract_inverted_index.drug | 65 |
| abstract_inverted_index.from | 55, 89, 230 |
| abstract_inverted_index.gene | 54, 114 |
| abstract_inverted_index.high | 105 |
| abstract_inverted_index.most | 107 |
| abstract_inverted_index.this | 194 |
| abstract_inverted_index.were | 41, 82 |
| abstract_inverted_index.with | 143 |
| abstract_inverted_index.(MGE) | 177 |
| abstract_inverted_index.(MIC) | 102 |
| abstract_inverted_index.-like | 190 |
| abstract_inverted_index.amino | 133 |
| abstract_inverted_index.could | 232 |
| abstract_inverted_index.feces | 40 |
| abstract_inverted_index.found | 180 |
| abstract_inverted_index.gene, | 200 |
| abstract_inverted_index.goose | 39, 90 |
| abstract_inverted_index.human | 240 |
| abstract_inverted_index.novel | 52, 111, 197 |
| abstract_inverted_index.plate | 44 |
| abstract_inverted_index.sites | 155 |
| abstract_inverted_index.their | 12 |
| abstract_inverted_index.which | 204 |
| abstract_inverted_index.work, | 195 |
| abstract_inverted_index.DW0551 | 120 |
| abstract_inverted_index.animal | 217, 238 |
| abstract_inverted_index.caused | 243 |
| abstract_inverted_index.enzyme | 73, 162 |
| abstract_inverted_index.family | 159 |
| abstract_inverted_index.feces, | 91 |
| abstract_inverted_index.genes. | 191 |
| abstract_inverted_index.genome | 58 |
| abstract_inverted_index.mobile | 174 |
| abstract_inverted_index.severe | 9 |
| abstract_inverted_index.shared | 138 |
| abstract_inverted_index.strong | 164 |
| abstract_inverted_index.toward | 169 |
| abstract_inverted_index.DW0551, | 87 |
| abstract_inverted_index.Methods | 36 |
| abstract_inverted_index.NAT_SF. | 160 |
| abstract_inverted_index.Results | 84 |
| abstract_inverted_index.animals | 231 |
| abstract_inverted_index.element | 176 |
| abstract_inverted_index.encoded | 116 |
| abstract_inverted_index.genetic | 175 |
| abstract_inverted_index.highest | 140 |
| abstract_inverted_index.kinetic | 74 |
| abstract_inverted_index.minimum | 99 |
| abstract_inverted_index.protein | 68 |
| abstract_inverted_index.regions | 184 |
| abstract_inverted_index.related | 245 |
| abstract_inverted_index.studies | 81 |
| abstract_inverted_index.variety | 209 |
| abstract_inverted_index.various | 60 |
| abstract_inverted_index.(52.63%) | 142 |
| abstract_inverted_index.Bacteria | 37 |
| abstract_inverted_index.Brucella | 85, 218 |
| abstract_inverted_index.activity | 168 |
| abstract_inverted_index.affinity | 165 |
| abstract_inverted_index.bacteria | 228 |
| abstract_inverted_index.becoming | 7 |
| abstract_inverted_index.cloning, | 64 |
| abstract_inverted_index.commonly | 15 |
| abstract_inverted_index.critical | 28 |
| abstract_inverted_index.diseases | 242 |
| abstract_inverted_index.flanking | 183 |
| abstract_inverted_index.identity | 141 |
| abstract_inverted_index.involved | 59 |
| abstract_inverted_index.isolate. | 220 |
| abstract_inverted_index.isolated | 42, 88, 229 |
| abstract_inverted_index.sequence | 135 |
| abstract_inverted_index.species. | 247 |
| abstract_inverted_index.testing, | 67 |
| abstract_inverted_index.Bacterial | 1 |
| abstract_inverted_index.amikacin, | 126 |
| abstract_inverted_index.analysis. | 75 |
| abstract_inverted_index.bacterial | 34, 57, 246 |
| abstract_inverted_index.catalytic | 167 |
| abstract_inverted_index.conferred | 121, 205 |
| abstract_inverted_index.conserved | 154 |
| abstract_inverted_index.contained | 151 |
| abstract_inverted_index.discovery | 19 |
| abstract_inverted_index.effective | 31 |
| abstract_inverted_index.exhibited | 163 |
| abstract_inverted_index.including | 62 |
| abstract_inverted_index.molecular | 22, 63 |
| abstract_inverted_index.resistant | 93 |
| abstract_inverted_index.treatment | 32, 236 |
| abstract_inverted_index.Background | 0 |
| abstract_inverted_index.Conclusion | 192 |
| abstract_inverted_index.antibiotic | 224 |
| abstract_inverted_index.designated | 201 |
| abstract_inverted_index.expression | 69 |
| abstract_inverted_index.identified | 214 |
| abstract_inverted_index.infectious | 241 |
| abstract_inverted_index.inhibitory | 100 |
| abstract_inverted_index.intermedia | 86, 119, 219 |
| abstract_inverted_index.kanamycin, | 127 |
| abstract_inverted_index.mechanisms | 23, 226 |
| abstract_inverted_index.netilmicin | 170 |
| abstract_inverted_index.performed. | 83 |
| abstract_inverted_index.prescribed | 16 |
| abstract_inverted_index.resistance | 2, 26, 53, 113, 122, 206, 225 |
| abstract_inverted_index.sequencing | 78 |
| abstract_inverted_index.sisomicin, | 125 |
| abstract_inverted_index.sisomicin. | 172 |
| abstract_inverted_index.streaking. | 45 |
| abstract_inverted_index.gentamicin, | 128 |
| abstract_inverted_index.infections. | 35 |
| abstract_inverted_index.netilmicin, | 124 |
| abstract_inverted_index.techniques, | 61 |
| abstract_inverted_index.tobramycin, | 129 |
| abstract_inverted_index.antibiotics, | 96 |
| abstract_inverted_index.antibiotics. | 17, 109 |
| abstract_inverted_index.functionally | 145 |
| abstract_inverted_index.increasingly | 8 |
| abstract_inverted_index.particularly | 104 |
| abstract_inverted_index.phylogenetic | 80 |
| abstract_inverted_index.whole-genome | 77 |
| abstract_inverted_index.AAC(6’)-Iaq | 137, 150 |
| abstract_inverted_index.AAC(6’)-If. | 149 |
| abstract_inverted_index.Additionally, | 76 |
| abstract_inverted_index.aac(6’)-Iaq | 115, 187, 189, 202 |
| abstract_inverted_index.characterized | 146 |
| abstract_inverted_index.concentration | 101 |
| abstract_inverted_index.purification, | 71 |
| abstract_inverted_index.ribostamycin. | 131 |
| abstract_inverted_index.Identification | 221 |
| abstract_inverted_index.aminoglycoside | 4, 25, 108, 112, 147, 198, 211 |
| abstract_inverted_index.antimicrobials | 5 |
| abstract_inverted_index.identification | 47 |
| abstract_inverted_index.susceptibility | 66 |
| abstract_inverted_index.antimicrobials, | 212 |
| abstract_inverted_index.characterization | 49 |
| abstract_inverted_index.acetyltransferase | 148, 158, 199 |
| cited_by_percentile_year.max | 97 |
| cited_by_percentile_year.min | 95 |
| corresponding_author_ids | https://openalex.org/A5101943568, https://openalex.org/A5112120357, https://openalex.org/A5101464152 |
| countries_distinct_count | 1 |
| institutions_distinct_count | 8 |
| corresponding_institution_ids | https://openalex.org/I27781120, https://openalex.org/I4210119853, https://openalex.org/I4210152737, https://openalex.org/I4210165678 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/3 |
| sustainable_development_goals[0].score | 0.46000000834465027 |
| sustainable_development_goals[0].display_name | Good health and well-being |
| citation_normalized_percentile.value | 0.8363375 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | True |