Scientific Reports • Vol 15 • No 1
Aberrant static and dynamic functional connectivity of insular cortex in patients with trigeminal neuralgia
July 2025 • Yuying Chen, Shumei Li, Meng Li, Lan Huang, Mian Jiang, Guo‐Min Li, Jinyan Chen, Jianhao Yan
The abnormal insular-related static and dynamic functional connectivity (sFC and dFC) in patients with trigeminal neuralgia (TN) is not well understood. Therefore, we aimed to explore alterations in the sFC and dFC of the insular cortex(IC) and the relationships between functional connectivity (FC) alterations and clinical measures in TN. The study included 40 patients with TN and 30 healthy controls (HCs) who underwent resting-state functional magnetic resonance imaging and completed the visual analog scale (VAS)…