Abstract P20. Does Antimicrobial Irrigation Of Breast Implant Pockets Reduce Capsular Contracture? A Systematic Review and Meta-analysis Article Swipe
James J. Drinane
,
Tayseer Chowdhry
,
Edmond F. Ritter
·
YOU?
·
· 2017
· Open Access
·
· DOI: https://doi.org/10.1097/01.gox.0000513394.19698.1e
YOU?
·
· 2017
· Open Access
·
· DOI: https://doi.org/10.1097/01.gox.0000513394.19698.1e
Purpose: The purpose of this study was to conduct a meta-analysis to determine if irrigation of breast implant pockets with antibiotics reduces the rate of capsular contracture. Capsular Contracture is the most common complication following primary augmentation mammoplasty, yet its etiology remains cryptogenic. Methods: PubMed was searched for publications from January 1 of 2000 through October of 2015. Studies with the following criteria were included: primary breast augmentation with implants; use of antimicrobial irrigation; and documentation of capsular contracture. Our primary outcome was incidence of capsular contracture. The quality of included studies was assessed independently. Studies were meta-analyzed to obtain a pooled odds ratio describing the effect of antimicrobial irrigation on capsular contracture. Results: The meta-analysis included eight studies and a total 7901 patients. 5216 patients received antimicrobial irrigation and 5824 patients did not. Analysis revealed that combined antimicrobial irrigation, the antibiotic irrigation subgroup and iodine subgroup were associated with an increased propensity for capsular contracture (OR 2.60; 95% CI, 2.3–2.94; OR 1.41; 95% CI, 1.17–1.70; OR 3.19; 95% CI,2.23–4.56; p<0.00001; I2=99.9) respectively. Conclusion: Antimicrobial irrigation of implant pockets fails to reduce the propensity for capsular contracture. The authors recommend that further prospective multicenter trials be conducted to further elucidate the role of antibiotic irrigation in capsular contracture.
Related Topics
Concepts
Capsular contracture
Medicine
Augmentation Mammoplasty
Meta-analysis
Implant
Surgery
Subgroup analysis
Antibiotics
Contracture
Antimicrobial
Breast augmentation
Internal medicine
Breast cancer
Breast reconstruction
Microbiology
Biology
Cancer
Metadata
- Type
- review
- Language
- en
- Landing Page
- https://doi.org/10.1097/01.gox.0000513394.19698.1e
- OA Status
- gold
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W2589075051
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W2589075051Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1097/01.gox.0000513394.19698.1eDigital Object Identifier
- Title
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Abstract P20. Does Antimicrobial Irrigation Of Breast Implant Pockets Reduce Capsular Contracture? A Systematic Review and Meta-analysisWork title
- Type
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reviewOpenAlex work type
- Language
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enPrimary language
- Publication year
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2017Year of publication
- Publication date
-
2017-02-01Full publication date if available
- Authors
-
James J. Drinane, Tayseer Chowdhry, Edmond F. RitterList of authors in order
- Landing page
-
https://doi.org/10.1097/01.gox.0000513394.19698.1ePublisher landing page
- Open access
-
YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
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https://doi.org/10.1097/01.gox.0000513394.19698.1eDirect OA link when available
- Concepts
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Capsular contracture, Medicine, Augmentation Mammoplasty, Meta-analysis, Implant, Surgery, Subgroup analysis, Antibiotics, Contracture, Antimicrobial, Breast augmentation, Internal medicine, Breast cancer, Breast reconstruction, Microbiology, Biology, CancerTop concepts (fields/topics) attached by OpenAlex
- Cited by
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0Total citation count in OpenAlex
- Related works (count)
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10Other works algorithmically related by OpenAlex
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| publication_date | 2017-02-01 |
| publication_year | 2017 |
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