Acceptability determinants of a proposal to reduce antiretroviral treatment to an oral two-drug regimen among patients living with HIV and physicians in France Article Swipe
Anne Sophie Petit
,
Clotilde Allavena
,
David Zucman
,
Laurent Hocqueloux
,
Olivia Rousset‐Torrente
,
Guillaume Roucoux
,
Claudine Duvivier
,
Gwenaël Le Moal
,
Olivier Chassany
,
Martin Duracinský
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1371/journal.pone.0308784
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1371/journal.pone.0308784
An oral two-drug regimen (O2DR) in the form of a once-a-day single tablet is now recommended for treatment switching and treatment initiation for HIV. In clinical care, the process of treatment change refers to adaptation issues, both individual and within the care relationship. The study aim is to present the determinants involved in the acceptability of switching to O2DR in the PROBI (Patient-Reported Outcomes BItherapy) qualitative study. The study includes 30 interviews: 15 were conducted with doctors caring for people living with HIV, 15 were conducted with patients who had been offered a change of treatment. A double analysis was carried out: lexicometric analysis to highlight the structuring of the discourse around the change in treatment and a thematic analysis to understand the associated issues more precisely. The results highlighted common concerns with respect to switching to O2DR. Also, the caregiver-patient relationship was a central determinant in treatment switching. Information, knowledge and representations of O2DR are also factors facilitating treatment change and should be taken into account for doctors’ and patients’ adherence.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1371/journal.pone.0308784
- OA Status
- gold
- Cited By
- 2
- References
- 32
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4402978042
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4402978042Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1371/journal.pone.0308784Digital Object Identifier
- Title
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Acceptability determinants of a proposal to reduce antiretroviral treatment to an oral two-drug regimen among patients living with HIV and physicians in FranceWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2024Year of publication
- Publication date
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2024-09-30Full publication date if available
- Authors
-
Anne Sophie Petit, Clotilde Allavena, David Zucman, Laurent Hocqueloux, Olivia Rousset‐Torrente, Guillaume Roucoux, Claudine Duvivier, Gwenaël Le Moal, Olivier Chassany, Martin DuracinskýList of authors in order
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https://doi.org/10.1371/journal.pone.0308784Publisher landing page
- Open access
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YesWhether a free full text is available
- OA status
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goldOpen access status per OpenAlex
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https://doi.org/10.1371/journal.pone.0308784Direct OA link when available
- Concepts
-
Thematic analysis, Regimen, Medicine, Qualitative research, Human immunodeficiency virus (HIV), Family medicine, Drug, Psychiatry, Internal medicine, Social science, SociologyTop concepts (fields/topics) attached by OpenAlex
- Cited by
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2Total citation count in OpenAlex
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2025: 2Per-year citation counts (last 5 years)
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32Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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| countries_distinct_count | 1 |
| institutions_distinct_count | 10 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/3 |
| sustainable_development_goals[0].score | 0.7699999809265137 |
| sustainable_development_goals[0].display_name | Good health and well-being |
| citation_normalized_percentile.value | 0.7741642 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |