Acute exercise activates the AHR in peripheral blood mononuclear cells in an intensity-dependent manner Article Swipe
Related Concepts
Peripheral blood mononuclear cell
Peripheral
Peripheral blood
Intensity (physics)
Medicine
Internal medicine
Immunology
Chemistry
Physics
Optics
Biochemistry
In vitro
Niklas Joisten
,
David Walzik
,
Alexander Schenk
,
Alan J. Metcalfe
,
Sergen Belen
,
Kirill Schaaf
,
Daniel Jacko
,
Sebastian Gehlert
,
Polyxeni Spiliopoulou
,
Ann‐Marie Garzinsky
,
Mario Thevis
,
Ludwig Rappelt
,
Lars Donath
,
Sven G. Meuth
,
Wilhelm Bloch
,
Philipp Zimmer
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1152/ajpcell.00282.2024
· OA: W4399973490
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1152/ajpcell.00282.2024
· OA: W4399973490
The findings of this study show that acute endurance exercise activates a receptor that has been described to integrate metabolic signals into the immune system. We uncover a potential mechanistic link on how exercise modulates the immune system through the kynurenine pathway-AHR axis, potentially underlying exercise-induced benefits in various chronic diseases and of relevance for other cell types.
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