Additional Guidance on the Use of the PRESERFLO™ MicroShunt in the Treatment of Glaucoma: Insights from a Second Delphi Consensus Panel Article Swipe
Anthony P. Khawaja
,
Luís Abegão Pinto
,
Ingeborg Stalmans
,
Florent Aptel
,
Anna Barkander
,
Keith Barton
,
Henny J. M. Beckers
,
Milko E. Iliev
,
Thomas Klink
,
Giorgio Marchini
,
J.M. Martínez-de-la-Casa
,
Lutz E. Pillunat
,
Jan H. Simonsen
,
Clemens Vass
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1007/s40123-024-00902-5
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1007/s40123-024-00902-5
INTRODUCTION: The PRESERFLO™ MicroShunt (PMS) has been proven to significantly lower intraocular pressure (IOP) in patients with glaucoma and has been available for use since 2019. With increasing published evidence and growing experience of glaucoma surgeons, the aim of this modified Delphi panel was to build on the findings of a previous Delphi panel conducted in 2021 and provide further guidance on the role of the PMS to treat patients with glaucoma in Europe. METHODS: Thirteen European glaucoma surgeons experienced in the PMS procedure participated in a 3-round modified Delphi panel. A targeted literature review and expert steering committee guided Round 1 questionnaire development. Consensus was pre-defined at a threshold of ≥ 70% of panellists selecting 'strongly agree'/'agree' or 'strongly disagree'/'disagree' for 6-point Likert scale questions or ≥ 70% selecting the same option for multiple or single-choice questions. Questions not reaching consensus were restated/revised for the next round, following guidance from free-text responses/scoping questions. RESULTS: In total, 28% (n = 9/32), 52% (n = 16/31) and 91% (n = 10/11) of statements reached consensus in Rounds 1, 2 and 3, respectively. There was agreement that the PMS may be used in patients with pigmentary, post-trauma or post-vitrectomy glaucoma and for patients with uveitic glaucoma without active inflammation. The PMS may be more suitable for patients with contact lenses than other subconjunctival filtering surgeries, without eliminating bleb-associated risks. Consensus was reached that combining PMS implantation and phacoemulsification may be as safe as standalone PMS surgery, but further efficacy data are required. Following a late rise in IOP ≥ 4 months post-surgery, topical aqueous suppressant drops or bleb revision may be suitable management options. CONCLUSIONS: This Delphi panel builds on the considerations explored in the 2021 Delphi panel and provides further detailed guidance for glaucoma surgeons on the use of the PMS, reflecting the availability of novel evidence and surgical experience. Videos are available for this article.
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- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1007/s40123-024-00902-5
- https://link.springer.com/content/pdf/10.1007/s40123-024-00902-5.pdf
- OA Status
- gold
- Cited By
- 7
- References
- 23
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4394569733
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4394569733Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1007/s40123-024-00902-5Digital Object Identifier
- Title
-
Additional Guidance on the Use of the PRESERFLO™ MicroShunt in the Treatment of Glaucoma: Insights from a Second Delphi Consensus PanelWork title
- Type
-
articleOpenAlex work type
- Language
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enPrimary language
- Publication year
-
2024Year of publication
- Publication date
-
2024-04-08Full publication date if available
- Authors
-
Anthony P. Khawaja, Luís Abegão Pinto, Ingeborg Stalmans, Florent Aptel, Anna Barkander, Keith Barton, Henny J. M. Beckers, Milko E. Iliev, Thomas Klink, Giorgio Marchini, J.M. Martínez-de-la-Casa, Lutz E. Pillunat, Jan H. Simonsen, Clemens VassList of authors in order
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https://doi.org/10.1007/s40123-024-00902-5Publisher landing page
- PDF URL
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https://link.springer.com/content/pdf/10.1007/s40123-024-00902-5.pdfDirect link to full text PDF
- Open access
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YesWhether a free full text is available
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goldOpen access status per OpenAlex
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https://link.springer.com/content/pdf/10.1007/s40123-024-00902-5.pdfDirect OA link when available
- Concepts
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Glaucoma, Delphi method, Medicine, Delphi, Ophthalmology, Optometry, Computer science, Artificial intelligence, Operating systemTop concepts (fields/topics) attached by OpenAlex
- Cited by
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7Total citation count in OpenAlex
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2025: 5, 2024: 2Per-year citation counts (last 5 years)
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10Other works algorithmically related by OpenAlex
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| abstract_inverted_index.'strongly | 116, 119 |
| abstract_inverted_index.Consensus | 104, 227 |
| abstract_inverted_index.Following | 250 |
| abstract_inverted_index.Questions | 138 |
| abstract_inverted_index.agreement | 183 |
| abstract_inverted_index.available | 21, 311 |
| abstract_inverted_index.combining | 231 |
| abstract_inverted_index.committee | 98 |
| abstract_inverted_index.conducted | 54 |
| abstract_inverted_index.consensus | 141, 173 |
| abstract_inverted_index.filtering | 221 |
| abstract_inverted_index.following | 148 |
| abstract_inverted_index.free-text | 151 |
| abstract_inverted_index.procedure | 83 |
| abstract_inverted_index.published | 28 |
| abstract_inverted_index.questions | 125 |
| abstract_inverted_index.required. | 249 |
| abstract_inverted_index.selecting | 115, 129 |
| abstract_inverted_index.surgeons, | 35 |
| abstract_inverted_index.threshold | 109 |
| abstract_inverted_index.MicroShunt | 3 |
| abstract_inverted_index.experience | 32 |
| abstract_inverted_index.increasing | 27 |
| abstract_inverted_index.literature | 93 |
| abstract_inverted_index.management | 270 |
| abstract_inverted_index.panellists | 114 |
| abstract_inverted_index.questions. | 137, 153 |
| abstract_inverted_index.reflecting | 300 |
| abstract_inverted_index.standalone | 241 |
| abstract_inverted_index.statements | 171 |
| abstract_inverted_index.surgeries, | 222 |
| abstract_inverted_index.eliminating | 224 |
| abstract_inverted_index.experience. | 308 |
| abstract_inverted_index.experienced | 79 |
| abstract_inverted_index.intraocular | 11 |
| abstract_inverted_index.pigmentary, | 193 |
| abstract_inverted_index.post-trauma | 194 |
| abstract_inverted_index.pre-defined | 106 |
| abstract_inverted_index.suppressant | 262 |
| abstract_inverted_index.CONCLUSIONS: | 272 |
| abstract_inverted_index.PRESERFLO™ | 2 |
| abstract_inverted_index.availability | 302 |
| abstract_inverted_index.development. | 103 |
| abstract_inverted_index.implantation | 233 |
| abstract_inverted_index.participated | 84 |
| abstract_inverted_index.INTRODUCTION: | 0 |
| abstract_inverted_index.inflammation. | 206 |
| abstract_inverted_index.post-surgery, | 259 |
| abstract_inverted_index.questionnaire | 102 |
| abstract_inverted_index.respectively. | 180 |
| abstract_inverted_index.significantly | 9 |
| abstract_inverted_index.single-choice | 136 |
| abstract_inverted_index.agree'/'agree' | 117 |
| abstract_inverted_index.considerations | 279 |
| abstract_inverted_index.bleb-associated | 225 |
| abstract_inverted_index.post-vitrectomy | 196 |
| abstract_inverted_index.subconjunctival | 220 |
| abstract_inverted_index.restated/revised | 143 |
| abstract_inverted_index.responses/scoping | 152 |
| abstract_inverted_index.phacoemulsification | 235 |
| abstract_inverted_index.disagree'/'disagree' | 120 |
| cited_by_percentile_year.max | 98 |
| cited_by_percentile_year.min | 94 |
| countries_distinct_count | 12 |
| institutions_distinct_count | 14 |
| citation_normalized_percentile.value | 0.95254783 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | True |