Adherence to Repeat Screening Completion for Colorectal Cancer Using the Multi-Target Stool DNA Test: Real-World Analysis of Patients from Federally Qualified Health Centers Article Swipe

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Mallik Greene , Timo Pew , Jorge Zapatier , Juanita Lopez , Paul J. Limburg , Martha Duarte ·

YOU? · · 2025 · Open Access · · DOI: https://doi.org/10.1177/21501319251348099

Introduction/Objectives: This real-world study examined adherence to repeat mt-sDNA among patients from federally qualified health centers (FQHCs) across the US and among different payer types. Methods: Data from Exact Sciences Laboratories, LLC were used for the period between January 1, 2023, and December 31, 2023, for those who had previously completed a mt-sDNA test. Study outcomes included adherence rate to mt-sDNA repeat screening and time to test return. Results: The study sample consisted of 19 536 eligible patients. The mt-sDNA repeat screening adherence rate was 79.7%, and the mean time to return the kit was 21.1 ± 20.8 days. Repeat screening adherence for patients with Medicare was 84.7%, Medicare Advantage was 80%, commercial insurance was 78.2%, managed care organization was 74.6%, and Medicaid was 65.9% ( P < .001). Compared with patients covered by commercial insurance, those covered by Medicaid had 42% lower odds of adhering to mt-sDNA repeat screening. Patients with 2 or more prior successful tests had a numerically shorter mean time to test return compared to those with only 1 prior successful test. Conclusions: While repeat screening adherence was generally high across patient demographic categories, there were significant differences by type of insurance coverage and number of prior successful mt-sDNA screenings.

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Medicine Medicaid Health insurance Test (biology) Family medicine Odds Internal medicine Colorectal cancer Colorectal cancer screening Logistic regression Health care Cancer Colonoscopy Economic growth Biology Paleontology Economics

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Type: article
Language: en
Landing Page: https://doi.org/10.1177/21501319251348099
OA Status: gold
Cited By: 1
References: 43
Related Works: 10
OpenAlex ID: https://openalex.org/W4411398199

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OpenAlex ID: https://openalex.org/W4411398199

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DOI: https://doi.org/10.1177/21501319251348099

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Title: Adherence to Repeat Screening Completion for Colorectal Cancer Using the Multi-Target Stool DNA Test: Real-World Analysis of Patients from Federally Qualified Health Centers

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Type: article

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Language: en

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Publication year: 2025

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Publication date: 2025-06-01

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Authors: Mallik Greene, Timo Pew, Jorge Zapatier, Juanita Lopez, Paul J. Limburg, Martha Duarte

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Landing page: https://doi.org/10.1177/21501319251348099

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OA URL: https://doi.org/10.1177/21501319251348099

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Concepts: Medicine, Medicaid, Health insurance, Test (biology), Family medicine, Odds, Internal medicine, Colorectal cancer, Colorectal cancer screening, Logistic regression, Health care, Cancer, Colonoscopy, Economic growth, Biology, Paleontology, Economics

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Cited by: 1

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