Administrative coding of frailty: Its association with clinical outcomes and resource use in kidney transplantation Article Swipe
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· 2023
· Open Access
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· DOI: https://doi.org/10.1111/ctr.15200
Introduction Although not formalized into current risk assessment models, frailty has been associated with negative postoperative outcomes in many specialties. However, national analyses of the association between frailty and post‐transplant outcomes following kidney transplantation (KT) are lacking. Methods This was a retrospective cohort study of adults undergoing KT from 2016 to 2020 in the Nationwide Readmissions Databases. Frailty was defined using the Johns Hopkins Adjusted Clinical Groups frailty indicator. Results Of an estimated 95 765 patients undergoing KT during the study period, 4918 (5.1%) were frail. After risk adjustment, frail patients were associated with significantly higher odds of in‐hospital mortality (AOR 2.17, 95% CI: 1.33–3.57) compared to their non‐frail counterparts. Our findings indicate that frail patients had an average increase in postoperative hospital stay of 1.44 days, a $2300 increase in hospitalization costs, as well as higher odds of developing a major perioperative complication as compared to their non‐frail counterparts. Frailty was also associated with greater adjusted risk of non‐home discharge. Conclusions Frailty, as identified by administrative coding, is independently associated with worse surgical outcomes, including increased mortality and resource use, in adults undergoing KT. Given the already limited donor organ pool, novel efforts are needed to ensure adequate optimization and timely post‐transplantation care of the growing frail cohort undergoing KT.
Related Topics
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1111/ctr.15200
- https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/ctr.15200
- OA Status
- hybrid
- Cited By
- 2
- References
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- Related Works
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- OpenAlex ID
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https://openalex.org/W4389265458Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1111/ctr.15200Digital Object Identifier
- Title
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Administrative coding of frailty: Its association with clinical outcomes and resource use in kidney transplantationWork title
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2023Year of publication
- Publication date
-
2023-12-01Full publication date if available
- Authors
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Saad Mallick, Sara Sakowitz, Syed Shahyan Bakhtiyar, Nikhil Chervu, Alberto Valenzuela, Shineui Kim, Peyman BenharashList of authors in order
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https://doi.org/10.1111/ctr.15200Publisher landing page
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https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/ctr.15200Direct link to full text PDF
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YesWhether a free full text is available
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hybridOpen access status per OpenAlex
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https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/ctr.15200Direct OA link when available
- Concepts
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Medicine, Perioperative, Odds, Odds ratio, Retrospective cohort study, Transplantation, Kidney transplantation, Cohort, Resource use, Intensive care medicine, Cohort study, Emergency medicine, Confounding, Internal medicine, Surgery, Logistic regression, Natural resource economics, EconomicsTop concepts (fields/topics) attached by OpenAlex
- Cited by
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2Total citation count in OpenAlex
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2025: 1, 2024: 1Per-year citation counts (last 5 years)
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47Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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