Advanced Photonic Sensors Based on Interband Cascade Lasers for Real-Time Mouse Breath Analysis Article Swipe
Erhan Tütüncü
,
Markus Nägele
,
S. Becker
,
M. Fischer
,
Johannes Koeth
,
Christian Wolf
,
Stefan Köstler
,
Volker Ribitsch
,
Andrea Teuber
,
Michael Gröger
,
Sandra Kress
,
Martin Wepler
,
Ulrich Wachter
,
J. Vogt
,
Peter Radermacher
,
Boris Mizaikoff
·
YOU?
·
· 2018
· Open Access
·
· DOI: https://doi.org/10.1021/acssensors.8b00477
YOU?
·
· 2018
· Open Access
·
· DOI: https://doi.org/10.1021/acssensors.8b00477
A multiparameter gas sensor based on distributed feedback interband cascade lasers emitting at 4.35 μm and ultrafast electro-spun luminescence oxygen sensors has been developed for the quantification and continuous monitoring of 13CO2/12CO2 isotopic ratio changes and oxygen in exhaled mouse breath samples. Mid-infrared absorption spectra for quantitatively monitoring the enrichment of 13CO2 levels were recorded in a miniaturized dual-channel substrate-integrated hollow waveguide using balanced ratiometric detection, whereas luminescence quenching was used for synchronously detecting exhaled oxygen levels. Allan variance analysis verified a CO2 measurement precision of 1.6‰ during a 480 s integration time. Routine online monitoring of exhaled mouse breath was performed in 14 mechanically ventilated and instrumented mice and demonstrated the feasibility of online isotope-selective exhaled breath analysis within microliters of probed gas samples using the reported combined sensor platform.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1021/acssensors.8b00477
- OA Status
- green
- Cited By
- 27
- References
- 23
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W2886132568
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W2886132568Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1021/acssensors.8b00477Digital Object Identifier
- Title
-
Advanced Photonic Sensors Based on Interband Cascade Lasers for Real-Time Mouse Breath AnalysisWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2018Year of publication
- Publication date
-
2018-08-03Full publication date if available
- Authors
-
Erhan Tütüncü, Markus Nägele, S. Becker, M. Fischer, Johannes Koeth, Christian Wolf, Stefan Köstler, Volker Ribitsch, Andrea Teuber, Michael Gröger, Sandra Kress, Martin Wepler, Ulrich Wachter, J. Vogt, Peter Radermacher, Boris MizaikoffList of authors in order
- Landing page
-
https://doi.org/10.1021/acssensors.8b00477Publisher landing page
- Open access
-
YesWhether a free full text is available
- OA status
-
greenOpen access status per OpenAlex
- OA URL
-
https://nbn-resolving.de/urn:nbn:de:bsz:289-oparu-19037-6Direct OA link when available
- Concepts
-
Breath gas analysis, Luminescence, Laser, Materials science, Quenching (fluorescence), Optoelectronics, Analytical Chemistry (journal), Oxygen, Substrate (aquarium), Photonics, Chemistry, Optics, Chromatography, Physics, Fluorescence, Oceanography, Organic chemistry, GeologyTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
27Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 3, 2024: 6, 2023: 3, 2022: 5, 2021: 1Per-year citation counts (last 5 years)
- References (count)
-
23Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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