Adverse Events and Serological Responses After SARS-CoV-2 Vaccination in Individuals With Inflammatory Bowel Disease Article Swipe
Ante Markovinović
,
Joshua Quan
,
Michelle Herauf
,
Lindsay Hracs
,
Joseph W. Windsor
,
Nastaran Sharifi
,
Stephanie Coward
,
Léa Caplan
,
Julia Gorospe
,
Kenneth Ernest‐Suarez
,
Christopher Ma
,
Remo Panaccione
,
R Ingram
,
Jamil N. Kanji
,
Graham Tipples
,
Jessalyn K. Holodinsky
,
Çharles N. Bernstein
,
Douglas J. Mahoney
,
Sasha Bernatsky
,
Eric I. Benchimol
,
Gilaad G. Kaplan
·
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.14309/ajg.0000000000002337
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.14309/ajg.0000000000002337
INTRODUCTION: We determined adverse events after 4 doses of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) vaccine in those with inflammatory bowel disease (IBD), associations between antibodies and injection site reactions (ISR), and risk of IBD flare. METHODS: Individuals with IBD were interviewed for adverse events to SARS-CoV-2 vaccine. Multivariable linear regression assessed the association between antibody titers and ISR. RESULTS: Severe adverse events occurred in 0.03%. ISR were significantly associated with antibody levels after the fourth dose (geometric mean ratio = 2.56; 95% confidence interval 1.18–5.57). No cases of IBD flare occurred. DISCUSSION: SARS-CoV-2 vaccines are safe for those with IBD. ISR after the fourth dose may indicate increased antibodies.
Related Topics
Concepts
Medicine
Adverse effect
Inflammatory bowel disease
Vaccination
Serology
Immunology
Antibody titer
Confidence interval
Antibody
Coronavirus
Internal medicine
Disease
Titer
Coronavirus disease 2019 (COVID-19)
Infectious disease (medical specialty)
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.14309/ajg.0000000000002337
- OA Status
- hybrid
- Cited By
- 6
- References
- 15
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4377225277
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4377225277Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.14309/ajg.0000000000002337Digital Object Identifier
- Title
-
Adverse Events and Serological Responses After SARS-CoV-2 Vaccination in Individuals With Inflammatory Bowel DiseaseWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2023Year of publication
- Publication date
-
2023-05-22Full publication date if available
- Authors
-
Ante Markovinović, Joshua Quan, Michelle Herauf, Lindsay Hracs, Joseph W. Windsor, Nastaran Sharifi, Stephanie Coward, Léa Caplan, Julia Gorospe, Kenneth Ernest‐Suarez, Christopher Ma, Remo Panaccione, R Ingram, Jamil N. Kanji, Graham Tipples, Jessalyn K. Holodinsky, Çharles N. Bernstein, Douglas J. Mahoney, Sasha Bernatsky, Eric I. Benchimol, Gilaad G. KaplanList of authors in order
- Landing page
-
https://doi.org/10.14309/ajg.0000000000002337Publisher landing page
- Open access
-
YesWhether a free full text is available
- OA status
-
hybridOpen access status per OpenAlex
- OA URL
-
https://doi.org/10.14309/ajg.0000000000002337Direct OA link when available
- Concepts
-
Medicine, Adverse effect, Inflammatory bowel disease, Vaccination, Serology, Immunology, Antibody titer, Confidence interval, Antibody, Coronavirus, Internal medicine, Disease, Titer, Coronavirus disease 2019 (COVID-19), Infectious disease (medical specialty)Top concepts (fields/topics) attached by OpenAlex
- Cited by
-
6Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 3, 2024: 1, 2023: 2Per-year citation counts (last 5 years)
- References (count)
-
15Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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