Adverse events associated with endoscopic retrograde cholangiopancreatography: protocol for a systematic review and meta-analysis Article Swipe
Nauzer Forbes
,
Grigorios I. Leontiadis
,
Marcus Vaska
,
B. Joseph Elmunzer
,
Yuhong Yuan
,
Kirles Bishay
,
Zhao Wu Meng
,
Jordan Iannuzzi
,
Dylan E. O’Sullivan
,
Brittany Mah
,
Arun C.R. Partridge
,
Amanda M. Henderson
,
Aatif Qureshi
,
Rajesh N. Keswani
,
Sachin Wani
,
Ronald Bridges
,
Steven J. Heitman
,
Robert J. Hilsden
,
Yibing Ruan
,
Darren R. Brenner
·
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.1136/bmjopen-2021-053302
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.1136/bmjopen-2021-053302
Introduction Endoscopic retrograde cholangiopancreatography (ERCP) is performed to diagnose and manage conditions of the biliary and pancreatic ducts. Though effective, it is associated with common adverse events (AEs). The purpose of this study is to systematically review ERCP AE rates and report up-to-date pooled estimates. Methods and analysis A comprehensive electronic search will be conducted of relevant medical databases through 10 November 2020. A study team of eight data abstracters will independently determine study eligibility, assess quality and abstract data in parallel, with any two concordant entries constituting agreement and with discrepancies resolved by consensus. The primary outcome will be the pooled incidence of post-ERCP pancreatitis, with secondary outcomes including post-ERCP bleeding, cholangitis, perforation, cholecystitis, death and unplanned healthcare encounters. Secondary outcomes will also include rates of specific and overall AEs within clinically relevant subgroups determined a priori. DerSimonian and Laird random effects models will be used to perform meta-analyses of these outcomes. Sources of heterogeneity will be explored via meta-regression. Subgroup analyses based on median dates of data collection across studies will be performed to determine whether AE rates have changed over time. Ethics and dissemination Ethics approval is not required for this study as it is a planned meta-analysis of previously published data. Participant consent is similarly not required. Dissemination is planned via presentation at relevant conferences in addition to publication in peer-reviewed journals. PROSPERO registration number CRD42020220221.
Related Topics
Concepts
Medicine
Endoscopic retrograde cholangiopancreatography
Meta-analysis
Perforation
Systematic review
Protocol (science)
Cholecystitis
MEDLINE
Pancreatitis
Subgroup analysis
Surgery
Internal medicine
Gallbladder
Alternative medicine
Pathology
Materials science
Political science
Law
Metallurgy
Punching
Metadata
- Type
- review
- Language
- en
- Landing Page
- https://doi.org/10.1136/bmjopen-2021-053302
- https://bmjopen.bmj.com/content/bmjopen/11/8/e053302.full.pdf
- OA Status
- gold
- Cited By
- 7
- References
- 42
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W3195665997
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W3195665997Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1136/bmjopen-2021-053302Digital Object Identifier
- Title
-
Adverse events associated with endoscopic retrograde cholangiopancreatography: protocol for a systematic review and meta-analysisWork title
- Type
-
reviewOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2021Year of publication
- Publication date
-
2021-08-01Full publication date if available
- Authors
-
Nauzer Forbes, Grigorios I. Leontiadis, Marcus Vaska, B. Joseph Elmunzer, Yuhong Yuan, Kirles Bishay, Zhao Wu Meng, Jordan Iannuzzi, Dylan E. O’Sullivan, Brittany Mah, Arun C.R. Partridge, Amanda M. Henderson, Aatif Qureshi, Rajesh N. Keswani, Sachin Wani, Ronald Bridges, Steven J. Heitman, Robert J. Hilsden, Yibing Ruan, Darren R. BrennerList of authors in order
- Landing page
-
https://doi.org/10.1136/bmjopen-2021-053302Publisher landing page
- PDF URL
-
https://bmjopen.bmj.com/content/bmjopen/11/8/e053302.full.pdfDirect link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
-
https://bmjopen.bmj.com/content/bmjopen/11/8/e053302.full.pdfDirect OA link when available
- Concepts
-
Medicine, Endoscopic retrograde cholangiopancreatography, Meta-analysis, Perforation, Systematic review, Protocol (science), Cholecystitis, MEDLINE, Pancreatitis, Subgroup analysis, Surgery, Internal medicine, Gallbladder, Alternative medicine, Pathology, Materials science, Political science, Law, Metallurgy, PunchingTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
7Total citation count in OpenAlex
- Citations by year (recent)
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2024: 3, 2023: 1, 2022: 2, 2021: 1Per-year citation counts (last 5 years)
- References (count)
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42Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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