Age Differences in Effects of Sacubitril/Valsartan on Cardiac Remodeling, Biomarkers, and Health Status Article Swipe
Sean Murphy
,
Jonathan H. Ward
,
Ileana L. Piña
,
G. Michael Felker
,
Javed Butler
,
Alan S. Maisel
,
Xiangyi Meng
,
Margaret F. Prescott
,
Scott D. Solomon
,
James L. Januzzi
·
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.1016/j.jchf.2022.07.001
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.1016/j.jchf.2022.07.001
Sac/Val resulted in significant improvements in prognostic biomarkers and measures of cardiac remodeling and health status from baseline to month 12 across age categories. Older study participants showed somewhat blunted reduction in NT-proBNP and less improvement in KCCQ-23 overall summary scores. (Effects of Sacubitril/Valsartan Therapy on Biomarkers, Myocardial Remodeling, and Outcomes [PROVE-HF]; NCT02887183).
Related Topics
Concepts
Ejection fraction
Medicine
Sacubitril, Valsartan
Cardiology
Internal medicine
Heart failure
Valsartan
Sacubitril
Natriuretic peptide
Ventricular remodeling
Troponin T
Blood pressure
Myocardial infarction
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1016/j.jchf.2022.07.001
- OA Status
- hybrid
- Cited By
- 15
- References
- 30
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4294898459
All OpenAlex metadata
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- OpenAlex ID
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https://openalex.org/W4294898459Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1016/j.jchf.2022.07.001Digital Object Identifier
- Title
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Age Differences in Effects of Sacubitril/Valsartan on Cardiac Remodeling, Biomarkers, and Health StatusWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2022Year of publication
- Publication date
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2022-09-07Full publication date if available
- Authors
-
Sean Murphy, Jonathan H. Ward, Ileana L. Piña, G. Michael Felker, Javed Butler, Alan S. Maisel, Xiangyi Meng, Margaret F. Prescott, Scott D. Solomon, James L. JanuzziList of authors in order
- Landing page
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https://doi.org/10.1016/j.jchf.2022.07.001Publisher landing page
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YesWhether a free full text is available
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hybridOpen access status per OpenAlex
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https://doi.org/10.1016/j.jchf.2022.07.001Direct OA link when available
- Concepts
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Ejection fraction, Medicine, Sacubitril, Valsartan, Cardiology, Internal medicine, Heart failure, Valsartan, Sacubitril, Natriuretic peptide, Ventricular remodeling, Troponin T, Blood pressure, Myocardial infarctionTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
15Total citation count in OpenAlex
- Citations by year (recent)
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2025: 7, 2024: 3, 2023: 5Per-year citation counts (last 5 years)
- References (count)
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30Number of works referenced by this work
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-
10Other works algorithmically related by OpenAlex
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