Air Pollution and Myocardial Infarction—A New Smoker’s Paradox? Article Swipe
Friederike von Lewinski
,
Franz Quehenberger
,
Michael Sacherer
,
Valentin Taucher
,
Christoph Strohhofer
,
Klemens Ablasser
,
Nicolas Verheyen
,
Caren Sourij
,
Andreas Kainz
,
Gerit Wünsch
,
Andrea Berghold
,
Thomas M. Berghaus
,
S Schnur
,
Andreas Zirlik
,
Dirk von Lewinski
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.3390/jcm13237324
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.3390/jcm13237324
Background/Objectives: Ambient air pollution is a significant public health concern, known to affect cardiovascular health adversely. Research has identified both long-term and short-term cardiovascular risks associated with various air pollutants, including those linked to acute coronary syndromes. However, the observed effects are rather small, with most data sourced from highly polluted regions. Methods: This study utilized a prospective registry database, documenting 12,581 myocardial infarction (MI) events in Styria, Austria from January 2007 to December 2015. Pollutants analyzed included particulate matter (PM2.5, PM10) and gases, such as NO2, CO, SO2, O3 and NOx. We employed generalized linear models to examine the interaction of each of these pollutants on the daily incidence of MI. Additionally, we conducted separate analyses for patients with specific comorbidities: diabetes mellitus (DM), arterial hypertension (HTN), heart failure with reduced ejection fraction (HFrEF), chronic obstructive pulmonary disease (COPD) and current smokers. Results: No significant associations were identified between any of the pollutants and MI incidence, both in the overall cohort and in patient subgroups with DM, HTN, HFrEF or COPD. However, among active smokers, we observed a decreased relative risk of MI associated with elevated levels of NO2, CO, SO2 and NOx on the day of MI (p < 0.01 for all pollutants). Conversely, an increased MI risk was associated with rising ozone levels (p = 0.0027). This counterintuitive finding aligns with previously published data and may suggest a new dimension to the “smoker’s paradox”. Conclusions: In regions with low pollution levels, air pollutants pose only minor or insignificant short-term risks for myocardial infarction. Active smokers exhibit an altered response to ambient air pollution.
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- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.3390/jcm13237324
- OA Status
- gold
- Cited By
- 1
- References
- 34
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4404959262
All OpenAlex metadata
Raw OpenAlex JSON
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https://openalex.org/W4404959262Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.3390/jcm13237324Digital Object Identifier
- Title
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Air Pollution and Myocardial Infarction—A New Smoker’s Paradox?Work title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2024Year of publication
- Publication date
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2024-12-02Full publication date if available
- Authors
-
Friederike von Lewinski, Franz Quehenberger, Michael Sacherer, Valentin Taucher, Christoph Strohhofer, Klemens Ablasser, Nicolas Verheyen, Caren Sourij, Andreas Kainz, Gerit Wünsch, Andrea Berghold, Thomas M. Berghaus, S Schnur, Andreas Zirlik, Dirk von LewinskiList of authors in order
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https://doi.org/10.3390/jcm13237324Publisher landing page
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YesWhether a free full text is available
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goldOpen access status per OpenAlex
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https://doi.org/10.3390/jcm13237324Direct OA link when available
- Concepts
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Medicine, Myocardial infarction, Air pollution, Pollution, Cardiology, Internal medicine, Chemistry, Ecology, Organic chemistry, BiologyTop concepts (fields/topics) attached by OpenAlex
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1Total citation count in OpenAlex
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2025: 1Per-year citation counts (last 5 years)
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10Other works algorithmically related by OpenAlex
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| abstract_inverted_index.associated | 25, 184, 211 |
| abstract_inverted_index.identified | 18, 148 |
| abstract_inverted_index.incidence, | 156 |
| abstract_inverted_index.infarction | 63 |
| abstract_inverted_index.myocardial | 62, 254 |
| abstract_inverted_index.pollutants | 105, 153, 245 |
| abstract_inverted_index.pollution. | 265 |
| abstract_inverted_index.previously | 224 |
| abstract_inverted_index.short-term | 22, 251 |
| abstract_inverted_index.syndromes. | 36 |
| abstract_inverted_index.Conversely, | 205 |
| abstract_inverted_index.documenting | 60 |
| abstract_inverted_index.generalized | 94 |
| abstract_inverted_index.infarction. | 255 |
| abstract_inverted_index.interaction | 100 |
| abstract_inverted_index.obstructive | 136 |
| abstract_inverted_index.paradox”. | 236 |
| abstract_inverted_index.particulate | 78 |
| abstract_inverted_index.pollutants, | 29 |
| abstract_inverted_index.prospective | 57 |
| abstract_inverted_index.significant | 6, 145 |
| abstract_inverted_index.Conclusions: | 237 |
| abstract_inverted_index.associations | 146 |
| abstract_inverted_index.hypertension | 126 |
| abstract_inverted_index.pollutants). | 204 |
| abstract_inverted_index.Additionally, | 112 |
| abstract_inverted_index.insignificant | 250 |
| abstract_inverted_index.“smoker’s | 235 |
| abstract_inverted_index.cardiovascular | 13, 23 |
| abstract_inverted_index.comorbidities: | 121 |
| abstract_inverted_index.counterintuitive | 220 |
| abstract_inverted_index.Background/Objectives: | 0 |
| cited_by_percentile_year.max | 95 |
| cited_by_percentile_year.min | 91 |
| corresponding_author_ids | https://openalex.org/A5009903680 |
| countries_distinct_count | 4 |
| institutions_distinct_count | 15 |
| corresponding_institution_ids | https://openalex.org/I202276237 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/3 |
| sustainable_development_goals[0].score | 0.8700000047683716 |
| sustainable_development_goals[0].display_name | Good health and well-being |
| citation_normalized_percentile.value | 0.67307732 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |