Wellcome Open Research • Vol 10
Ambient and passive collection of sleep and circadian data in bipolar disorder to understand symptom trajectories and clinical outcomes (AMBIENT-BD): Study protocol
May 2025 • Raahat Manrai, Duncan Swiffen, Cathy Wyse, Debbie Gray, Amy Ferguson, Lorna M. Lopez, Iain H. Campbell, Aja Louise Murray, Lorna Caddick, Emma Louise…
<ns3:p>Bipolar disorder is defined by extreme variability in mood, activity and sleep/wake patterns. To date, studies of sleep and circadian parameters in bipolar disorder have predominantly relied on short term monitoring over 1-2 weeks, leaving a need for approaches that can assess individual-level changes in sleep, activity and mood with high levels of temporal granularity. In the AMBIENT-BD study, we will optimise low intensity ambient and passive data collection techniques. These methods will allow us to infe…