Amniotic Fluid Embolism: a comprehensive review of diagnosis and management Article Swipe
Wiku Andonotopo
,
Muhammad Adrianes Bachnas
,
Julian Dewantiningrum
,
Besari Adi Pramono
,
Catur Dian Setiawan
,
Sri Sulistyowati
,
Milan Stanojević
,
Asım Kurjak
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1515/jpm-2025-0161
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1515/jpm-2025-0161
Introduction Amniotic Fluid Embolism (AFE) is a rare but catastrophic obstetric emergency characterized by the sudden entry of amniotic fluid or fetal debris into the maternal circulation. This triggers acute cardiopulmonary collapse, disseminated intravascular coagulation (DIC), and multi-organ failure. Despite its low incidence, AFE remains a significant contributor to maternal mortality worldwide. The pathophysiology is poorly understood, involving immune-mediated anaphylactoid reactions and mechanical vascular obstruction. Content This review provides a comprehensive synthesis of current knowledge on AFE, examining its epidemiology, pathophysiology, risk factors, clinical manifestations, diagnostic challenges, and management strategies. A systematic literature review was conducted following PRISMA guidelines, incorporating peer-reviewed articles and clinical protocols published from 2000 to 2024. Clinical tools such as diagnostic algorithms and resuscitation frameworks were developed from aggregated evidence and thematic analysis. Summary AFE typically presents intrapartum or in the immediate postpartum period with sudden hypoxia, hypotension, and coagulopathy. Diagnosis is clinical, as no single confirmatory biomarker currently exists. Management is primarily supportive, focusing on rapid resuscitation, hemodynamic stabilization, and aggressive coagulopathy correction. Emerging strategies such as the A-OK regimen (Atropine, Ondansetron, Ketorolac) are discussed as investigational approaches under consideration. Outlook AFE continues to challenge obstetric and critical care teams due to its abrupt onset and high fatality. Future priorities include the development of validated diagnostic biomarkers, refinement of therapeutic interventions, and establishment of standardized multidisciplinary response protocols to improve maternal and neonatal outcomes.
Related Topics
Concepts
Metadata
- Type
- review
- Language
- en
- Landing Page
- https://doi.org/10.1515/jpm-2025-0161
- https://www.degruyterbrill.com/document/doi/10.1515/jpm-2025-0161/pdf
- OA Status
- diamond
- References
- 18
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4413440716
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4413440716Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1515/jpm-2025-0161Digital Object Identifier
- Title
-
Amniotic Fluid Embolism: a comprehensive review of diagnosis and managementWork title
- Type
-
reviewOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2025Year of publication
- Publication date
-
2025-08-22Full publication date if available
- Authors
-
Wiku Andonotopo, Muhammad Adrianes Bachnas, Julian Dewantiningrum, Besari Adi Pramono, Catur Dian Setiawan, Sri Sulistyowati, Milan Stanojević, Asım KurjakList of authors in order
- Landing page
-
https://doi.org/10.1515/jpm-2025-0161Publisher landing page
- PDF URL
-
https://www.degruyterbrill.com/document/doi/10.1515/jpm-2025-0161/pdfDirect link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
diamondOpen access status per OpenAlex
- OA URL
-
https://www.degruyterbrill.com/document/doi/10.1515/jpm-2025-0161/pdfDirect OA link when available
- Concepts
-
Medicine, Amniotic fluid embolism, Intensive care medicine, Disseminated intravascular coagulation, Coagulopathy, Pregnancy, Surgery, Genetics, BiologyTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
0Total citation count in OpenAlex
- References (count)
-
18Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W4413440716 |
|---|---|
| doi | https://doi.org/10.1515/jpm-2025-0161 |
| ids.doi | https://doi.org/10.1515/jpm-2025-0161 |
| ids.pmid | https://pubmed.ncbi.nlm.nih.gov/40842297 |
| ids.openalex | https://openalex.org/W4413440716 |
| fwci | 0.0 |
| type | review |
| title | Amniotic Fluid Embolism: a comprehensive review of diagnosis and management |
| biblio.issue | |
| biblio.volume | |
| biblio.last_page | |
| biblio.first_page | |
| topics[0].id | https://openalex.org/T11389 |
| topics[0].field.id | https://openalex.org/fields/27 |
| topics[0].field.display_name | Medicine |
| topics[0].score | 0.9998999834060669 |
| topics[0].domain.id | https://openalex.org/domains/4 |
| topics[0].domain.display_name | Health Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/2735 |
| topics[0].subfield.display_name | Pediatrics, Perinatology and Child Health |
| topics[0].display_name | Maternal and fetal healthcare |
| topics[1].id | https://openalex.org/T10290 |
| topics[1].field.id | https://openalex.org/fields/27 |
| topics[1].field.display_name | Medicine |
| topics[1].score | 0.9950000047683716 |
| topics[1].domain.id | https://openalex.org/domains/4 |
| topics[1].domain.display_name | Health Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/2729 |
| topics[1].subfield.display_name | Obstetrics and Gynecology |
| topics[1].display_name | Pregnancy and preeclampsia studies |
| topics[2].id | https://openalex.org/T10453 |
| topics[2].field.id | https://openalex.org/fields/27 |
| topics[2].field.display_name | Medicine |
| topics[2].score | 0.9896000027656555 |
| topics[2].domain.id | https://openalex.org/domains/4 |
| topics[2].domain.display_name | Health Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/2729 |
| topics[2].subfield.display_name | Obstetrics and Gynecology |
| topics[2].display_name | Maternal and Perinatal Health Interventions |
| is_xpac | False |
| apc_list | |
| apc_paid | |
| concepts[0].id | https://openalex.org/C71924100 |
| concepts[0].level | 0 |
| concepts[0].score | 0.9061678051948547 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q11190 |
| concepts[0].display_name | Medicine |
| concepts[1].id | https://openalex.org/C2777143102 |
| concepts[1].level | 3 |
| concepts[1].score | 0.7734993696212769 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q1470833 |
| concepts[1].display_name | Amniotic fluid embolism |
| concepts[2].id | https://openalex.org/C177713679 |
| concepts[2].level | 1 |
| concepts[2].score | 0.7408137321472168 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q679690 |
| concepts[2].display_name | Intensive care medicine |
| concepts[3].id | https://openalex.org/C2778734968 |
| concepts[3].level | 2 |
| concepts[3].score | 0.6148746609687805 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q823027 |
| concepts[3].display_name | Disseminated intravascular coagulation |
| concepts[4].id | https://openalex.org/C2779936836 |
| concepts[4].level | 2 |
| concepts[4].score | 0.50668865442276 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q890200 |
| concepts[4].display_name | Coagulopathy |
| concepts[5].id | https://openalex.org/C2779234561 |
| concepts[5].level | 2 |
| concepts[5].score | 0.22023218870162964 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q11995 |
| concepts[5].display_name | Pregnancy |
| concepts[6].id | https://openalex.org/C141071460 |
| concepts[6].level | 1 |
| concepts[6].score | 0.21164381504058838 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q40821 |
| concepts[6].display_name | Surgery |
| concepts[7].id | https://openalex.org/C54355233 |
| concepts[7].level | 1 |
| concepts[7].score | 0.0 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q7162 |
| concepts[7].display_name | Genetics |
| concepts[8].id | https://openalex.org/C86803240 |
| concepts[8].level | 0 |
| concepts[8].score | 0.0 |
| concepts[8].wikidata | https://www.wikidata.org/wiki/Q420 |
| concepts[8].display_name | Biology |
| keywords[0].id | https://openalex.org/keywords/medicine |
| keywords[0].score | 0.9061678051948547 |
| keywords[0].display_name | Medicine |
| keywords[1].id | https://openalex.org/keywords/amniotic-fluid-embolism |
| keywords[1].score | 0.7734993696212769 |
| keywords[1].display_name | Amniotic fluid embolism |
| keywords[2].id | https://openalex.org/keywords/intensive-care-medicine |
| keywords[2].score | 0.7408137321472168 |
| keywords[2].display_name | Intensive care medicine |
| keywords[3].id | https://openalex.org/keywords/disseminated-intravascular-coagulation |
| keywords[3].score | 0.6148746609687805 |
| keywords[3].display_name | Disseminated intravascular coagulation |
| keywords[4].id | https://openalex.org/keywords/coagulopathy |
| keywords[4].score | 0.50668865442276 |
| keywords[4].display_name | Coagulopathy |
| keywords[5].id | https://openalex.org/keywords/pregnancy |
| keywords[5].score | 0.22023218870162964 |
| keywords[5].display_name | Pregnancy |
| keywords[6].id | https://openalex.org/keywords/surgery |
| keywords[6].score | 0.21164381504058838 |
| keywords[6].display_name | Surgery |
| language | en |
| locations[0].id | doi:10.1515/jpm-2025-0161 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S61009040 |
| locations[0].source.issn | 0300-5577, 1619-3997 |
| locations[0].source.type | journal |
| locations[0].source.is_oa | True |
| locations[0].source.issn_l | 0300-5577 |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | True |
| locations[0].source.display_name | Journal of Perinatal Medicine |
| locations[0].source.host_organization | https://openalex.org/P4310313990 |
| locations[0].source.host_organization_name | De Gruyter |
| locations[0].source.host_organization_lineage | https://openalex.org/P4310313990 |
| locations[0].source.host_organization_lineage_names | De Gruyter |
| locations[0].license | cc-by |
| locations[0].pdf_url | https://www.degruyterbrill.com/document/doi/10.1515/jpm-2025-0161/pdf |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | https://openalex.org/licenses/cc-by |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | Journal of Perinatal Medicine |
| locations[0].landing_page_url | https://doi.org/10.1515/jpm-2025-0161 |
| locations[1].id | pmid:40842297 |
| locations[1].is_oa | False |
| locations[1].source.id | https://openalex.org/S4306525036 |
| locations[1].source.issn | |
| locations[1].source.type | repository |
| locations[1].source.is_oa | False |
| locations[1].source.issn_l | |
| locations[1].source.is_core | False |
| locations[1].source.is_in_doaj | False |
| locations[1].source.display_name | PubMed |
| locations[1].source.host_organization | https://openalex.org/I1299303238 |
| locations[1].source.host_organization_name | National Institutes of Health |
| locations[1].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[1].license | |
| locations[1].pdf_url | |
| locations[1].version | publishedVersion |
| locations[1].raw_type | |
| locations[1].license_id | |
| locations[1].is_accepted | True |
| locations[1].is_published | True |
| locations[1].raw_source_name | Journal of perinatal medicine |
| locations[1].landing_page_url | https://pubmed.ncbi.nlm.nih.gov/40842297 |
| indexed_in | crossref, doaj, pubmed |
| authorships[0].author.id | https://openalex.org/A5027149217 |
| authorships[0].author.orcid | https://orcid.org/0000-0001-9062-8501 |
| authorships[0].author.display_name | Wiku Andonotopo |
| authorships[0].affiliations[0].raw_affiliation_string | Maternal-Fetal Medicine Division, Department of Obstetrics and Gynecology, Women Health Center , Eka Hospital , Tangerang , Banten , Indonesia |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Wiku Andonotopo |
| authorships[0].is_corresponding | False |
| authorships[0].raw_affiliation_strings | Maternal-Fetal Medicine Division, Department of Obstetrics and Gynecology, Women Health Center , Eka Hospital , Tangerang , Banten , Indonesia |
| authorships[1].author.id | https://openalex.org/A5080561796 |
| authorships[1].author.orcid | https://orcid.org/0000-0002-1710-3909 |
| authorships[1].author.display_name | Muhammad Adrianes Bachnas |
| authorships[1].countries | ID |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I119896790 |
| authorships[1].affiliations[0].raw_affiliation_string | Maternal-Fetal Medicine Division, Department of Obstetrics and Gynecology , Faculty of Medicine Sebelas Maret University, Dr. Moewardi General Hospital , Solo , Indonesia |
| authorships[1].institutions[0].id | https://openalex.org/I119896790 |
| authorships[1].institutions[0].ror | https://ror.org/021hq5q33 |
| authorships[1].institutions[0].type | education |
| authorships[1].institutions[0].lineage | https://openalex.org/I119896790 |
| authorships[1].institutions[0].country_code | ID |
| authorships[1].institutions[0].display_name | Sebelas Maret University |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Muhammad Adrianes Bachnas |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | Maternal-Fetal Medicine Division, Department of Obstetrics and Gynecology , Faculty of Medicine Sebelas Maret University, Dr. Moewardi General Hospital , Solo , Indonesia |
| authorships[2].author.id | https://openalex.org/A5065132623 |
| authorships[2].author.orcid | https://orcid.org/0000-0002-8937-1646 |
| authorships[2].author.display_name | Julian Dewantiningrum |
| authorships[2].affiliations[0].raw_affiliation_string | Maternal-Fetal Medicine Division, Department of Obstetrics and Gynecology, Women Health Center , Eka Hospital , Tangerang , Banten , Indonesia |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Julian Dewantiningrum |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | Maternal-Fetal Medicine Division, Department of Obstetrics and Gynecology, Women Health Center , Eka Hospital , Tangerang , Banten , Indonesia |
| authorships[3].author.id | https://openalex.org/A5091586331 |
| authorships[3].author.orcid | https://orcid.org/0000-0001-8342-2302 |
| authorships[3].author.display_name | Besari Adi Pramono |
| authorships[3].countries | ID |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I11855966, https://openalex.org/I2802302920 |
| authorships[3].affiliations[0].raw_affiliation_string | Maternal-Fetal Medicine Division Division, Department of Obstetrics and Gynecology , Medical Faculty of Diponegoro University, Dr. Kariadi Hospital , Semarang , Indonesia |
| authorships[3].institutions[0].id | https://openalex.org/I11855966 |
| authorships[3].institutions[0].ror | https://ror.org/056bjta22 |
| authorships[3].institutions[0].type | education |
| authorships[3].institutions[0].lineage | https://openalex.org/I11855966 |
| authorships[3].institutions[0].country_code | ID |
| authorships[3].institutions[0].display_name | Diponegoro University |
| authorships[3].institutions[1].id | https://openalex.org/I2802302920 |
| authorships[3].institutions[1].ror | https://ror.org/040f86t49 |
| authorships[3].institutions[1].type | healthcare |
| authorships[3].institutions[1].lineage | https://openalex.org/I2802302920 |
| authorships[3].institutions[1].country_code | ID |
| authorships[3].institutions[1].display_name | Dr. Kariadi Hospital |
| authorships[3].author_position | middle |
| authorships[3].raw_author_name | Mochammad Besari Adi Pramono |
| authorships[3].is_corresponding | False |
| authorships[3].raw_affiliation_strings | Maternal-Fetal Medicine Division Division, Department of Obstetrics and Gynecology , Medical Faculty of Diponegoro University, Dr. Kariadi Hospital , Semarang , Indonesia |
| authorships[4].author.id | https://openalex.org/A5086849177 |
| authorships[4].author.orcid | https://orcid.org/0000-0002-3642-9947 |
| authorships[4].author.display_name | Catur Dian Setiawan |
| authorships[4].countries | ID |
| authorships[4].affiliations[0].institution_ids | https://openalex.org/I4210087407 |
| authorships[4].affiliations[0].raw_affiliation_string | Indonesian Society of Obstetricians and Gynecologists (ISOG Banten) , Tangerang , Indonesia |
| authorships[4].affiliations[1].institution_ids | https://openalex.org/I4210105403 |
| authorships[4].affiliations[1].raw_affiliation_string | Department of Obstetrics and Gynecology , UniMedika Hospital , Tangerang , Banten , Indonesia |
| authorships[4].institutions[0].id | https://openalex.org/I4210087407 |
| authorships[4].institutions[0].ror | https://ror.org/00zrhqg94 |
| authorships[4].institutions[0].type | other |
| authorships[4].institutions[0].lineage | https://openalex.org/I4210087407 |
| authorships[4].institutions[0].country_code | ID |
| authorships[4].institutions[0].display_name | Indonesian Pediatric Society |
| authorships[4].institutions[1].id | https://openalex.org/I4210105403 |
| authorships[4].institutions[1].ror | https://ror.org/01gngef73 |
| authorships[4].institutions[1].type | education |
| authorships[4].institutions[1].lineage | https://openalex.org/I4210105403 |
| authorships[4].institutions[1].country_code | ID |
| authorships[4].institutions[1].display_name | Universitas Muhammadiyah Tangerang |
| authorships[4].author_position | middle |
| authorships[4].raw_author_name | Caroline Setiawan |
| authorships[4].is_corresponding | False |
| authorships[4].raw_affiliation_strings | Department of Obstetrics and Gynecology , UniMedika Hospital , Tangerang , Banten , Indonesia, Indonesian Society of Obstetricians and Gynecologists (ISOG Banten) , Tangerang , Indonesia |
| authorships[5].author.id | https://openalex.org/A5056268582 |
| authorships[5].author.orcid | https://orcid.org/0000-0003-1366-4431 |
| authorships[5].author.display_name | Sri Sulistyowati |
| authorships[5].countries | ID |
| authorships[5].affiliations[0].institution_ids | https://openalex.org/I119896790 |
| authorships[5].affiliations[0].raw_affiliation_string | Maternal-Fetal Medicine Division, Department of Obstetrics and Gynecology , Faculty of Medicine Sebelas Maret University, Sebelas Maret University Hospital , Solo , Indonesia |
| authorships[5].institutions[0].id | https://openalex.org/I119896790 |
| authorships[5].institutions[0].ror | https://ror.org/021hq5q33 |
| authorships[5].institutions[0].type | education |
| authorships[5].institutions[0].lineage | https://openalex.org/I119896790 |
| authorships[5].institutions[0].country_code | ID |
| authorships[5].institutions[0].display_name | Sebelas Maret University |
| authorships[5].author_position | middle |
| authorships[5].raw_author_name | Sri Sulistyowati |
| authorships[5].is_corresponding | False |
| authorships[5].raw_affiliation_strings | Maternal-Fetal Medicine Division, Department of Obstetrics and Gynecology , Faculty of Medicine Sebelas Maret University, Sebelas Maret University Hospital , Solo , Indonesia |
| authorships[6].author.id | https://openalex.org/A5101641062 |
| authorships[6].author.orcid | https://orcid.org/0000-0002-3124-5575 |
| authorships[6].author.display_name | Milan Stanojević |
| authorships[6].countries | PL |
| authorships[6].affiliations[0].institution_ids | https://openalex.org/I268303160 |
| authorships[6].affiliations[0].raw_affiliation_string | Department of Neonatology and Rare Diseases , Medical University of Warsaw , Warsaw , Poland |
| authorships[6].institutions[0].id | https://openalex.org/I268303160 |
| authorships[6].institutions[0].ror | https://ror.org/04p2y4s44 |
| authorships[6].institutions[0].type | education |
| authorships[6].institutions[0].lineage | https://openalex.org/I268303160 |
| authorships[6].institutions[0].country_code | PL |
| authorships[6].institutions[0].display_name | Medical University of Warsaw |
| authorships[6].author_position | middle |
| authorships[6].raw_author_name | Milan Stanojevic |
| authorships[6].is_corresponding | False |
| authorships[6].raw_affiliation_strings | Department of Neonatology and Rare Diseases , Medical University of Warsaw , Warsaw , Poland |
| authorships[7].author.id | https://openalex.org/A5091034398 |
| authorships[7].author.orcid | |
| authorships[7].author.display_name | Asım Kurjak |
| authorships[7].countries | HR |
| authorships[7].affiliations[0].institution_ids | https://openalex.org/I181343428 |
| authorships[7].affiliations[0].raw_affiliation_string | Department of Obstetrics and Gynecology , Medical School University of Zagreb , Zagreb , Croatia |
| authorships[7].institutions[0].id | https://openalex.org/I181343428 |
| authorships[7].institutions[0].ror | https://ror.org/00mv6sv71 |
| authorships[7].institutions[0].type | education |
| authorships[7].institutions[0].lineage | https://openalex.org/I181343428 |
| authorships[7].institutions[0].country_code | HR |
| authorships[7].institutions[0].display_name | University of Zagreb |
| authorships[7].author_position | last |
| authorships[7].raw_author_name | Asim Kurjak |
| authorships[7].is_corresponding | False |
| authorships[7].raw_affiliation_strings | Department of Obstetrics and Gynecology , Medical School University of Zagreb , Zagreb , Croatia |
| has_content.pdf | True |
| has_content.grobid_xml | False |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://www.degruyterbrill.com/document/doi/10.1515/jpm-2025-0161/pdf |
| open_access.oa_status | diamond |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | Amniotic Fluid Embolism: a comprehensive review of diagnosis and management |
| has_fulltext | False |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T11389 |
| primary_topic.field.id | https://openalex.org/fields/27 |
| primary_topic.field.display_name | Medicine |
| primary_topic.score | 0.9998999834060669 |
| primary_topic.domain.id | https://openalex.org/domains/4 |
| primary_topic.domain.display_name | Health Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/2735 |
| primary_topic.subfield.display_name | Pediatrics, Perinatology and Child Health |
| primary_topic.display_name | Maternal and fetal healthcare |
| related_works | https://openalex.org/W2523059389, https://openalex.org/W1970687298, https://openalex.org/W2559139664, https://openalex.org/W1505891614, https://openalex.org/W4381516419, https://openalex.org/W2435652224, https://openalex.org/W2924217923, https://openalex.org/W3045946681, https://openalex.org/W2353812743, https://openalex.org/W2387051543 |
| cited_by_count | 0 |
| locations_count | 2 |
| best_oa_location.id | doi:10.1515/jpm-2025-0161 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S61009040 |
| best_oa_location.source.issn | 0300-5577, 1619-3997 |
| best_oa_location.source.type | journal |
| best_oa_location.source.is_oa | True |
| best_oa_location.source.issn_l | 0300-5577 |
| best_oa_location.source.is_core | True |
| best_oa_location.source.is_in_doaj | True |
| best_oa_location.source.display_name | Journal of Perinatal Medicine |
| best_oa_location.source.host_organization | https://openalex.org/P4310313990 |
| best_oa_location.source.host_organization_name | De Gruyter |
| best_oa_location.source.host_organization_lineage | https://openalex.org/P4310313990 |
| best_oa_location.source.host_organization_lineage_names | De Gruyter |
| best_oa_location.license | cc-by |
| best_oa_location.pdf_url | https://www.degruyterbrill.com/document/doi/10.1515/jpm-2025-0161/pdf |
| best_oa_location.version | publishedVersion |
| best_oa_location.raw_type | journal-article |
| best_oa_location.license_id | https://openalex.org/licenses/cc-by |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | True |
| best_oa_location.raw_source_name | Journal of Perinatal Medicine |
| best_oa_location.landing_page_url | https://doi.org/10.1515/jpm-2025-0161 |
| primary_location.id | doi:10.1515/jpm-2025-0161 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S61009040 |
| primary_location.source.issn | 0300-5577, 1619-3997 |
| primary_location.source.type | journal |
| primary_location.source.is_oa | True |
| primary_location.source.issn_l | 0300-5577 |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | True |
| primary_location.source.display_name | Journal of Perinatal Medicine |
| primary_location.source.host_organization | https://openalex.org/P4310313990 |
| primary_location.source.host_organization_name | De Gruyter |
| primary_location.source.host_organization_lineage | https://openalex.org/P4310313990 |
| primary_location.source.host_organization_lineage_names | De Gruyter |
| primary_location.license | cc-by |
| primary_location.pdf_url | https://www.degruyterbrill.com/document/doi/10.1515/jpm-2025-0161/pdf |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | https://openalex.org/licenses/cc-by |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | Journal of Perinatal Medicine |
| primary_location.landing_page_url | https://doi.org/10.1515/jpm-2025-0161 |
| publication_date | 2025-08-22 |
| publication_year | 2025 |
| referenced_works | https://openalex.org/W2462001482, https://openalex.org/W4242040560, https://openalex.org/W1981566080, https://openalex.org/W1996466741, https://openalex.org/W2005167337, https://openalex.org/W2156059813, https://openalex.org/W2593908940, https://openalex.org/W2805054204, https://openalex.org/W4294215472, https://openalex.org/W3118615836, https://openalex.org/W2153982347, https://openalex.org/W2330142490, https://openalex.org/W2012507654, https://openalex.org/W2327713837, https://openalex.org/W4251473947, https://openalex.org/W4240733337, https://openalex.org/W4239831396, https://openalex.org/W2780631754 |
| referenced_works_count | 18 |
| abstract_inverted_index.A | 91 |
| abstract_inverted_index.a | 7, 46, 70 |
| abstract_inverted_index.as | 114, 148, 172, 181 |
| abstract_inverted_index.by | 14 |
| abstract_inverted_index.in | 134 |
| abstract_inverted_index.is | 6, 55, 146, 156 |
| abstract_inverted_index.no | 149 |
| abstract_inverted_index.of | 18, 73, 209, 214, 219 |
| abstract_inverted_index.on | 76, 160 |
| abstract_inverted_index.or | 21, 133 |
| abstract_inverted_index.to | 49, 109, 189, 197, 224 |
| abstract_inverted_index.AFE | 44, 129, 187 |
| abstract_inverted_index.The | 53 |
| abstract_inverted_index.and | 37, 62, 88, 103, 117, 125, 143, 165, 192, 201, 217, 227 |
| abstract_inverted_index.are | 179 |
| abstract_inverted_index.but | 9 |
| abstract_inverted_index.due | 196 |
| abstract_inverted_index.its | 41, 79, 198 |
| abstract_inverted_index.low | 42 |
| abstract_inverted_index.the | 15, 25, 135, 173, 207 |
| abstract_inverted_index.was | 95 |
| abstract_inverted_index.2000 | 108 |
| abstract_inverted_index.A-OK | 174 |
| abstract_inverted_index.AFE, | 77 |
| abstract_inverted_index.This | 28, 67 |
| abstract_inverted_index.care | 194 |
| abstract_inverted_index.from | 107, 122 |
| abstract_inverted_index.high | 202 |
| abstract_inverted_index.into | 24 |
| abstract_inverted_index.rare | 8 |
| abstract_inverted_index.risk | 82 |
| abstract_inverted_index.such | 113, 171 |
| abstract_inverted_index.were | 120 |
| abstract_inverted_index.with | 139 |
| abstract_inverted_index.(AFE) | 5 |
| abstract_inverted_index.2024. | 110 |
| abstract_inverted_index.Fluid | 3 |
| abstract_inverted_index.acute | 30 |
| abstract_inverted_index.entry | 17 |
| abstract_inverted_index.fetal | 22 |
| abstract_inverted_index.fluid | 20 |
| abstract_inverted_index.onset | 200 |
| abstract_inverted_index.rapid | 161 |
| abstract_inverted_index.teams | 195 |
| abstract_inverted_index.tools | 112 |
| abstract_inverted_index.under | 184 |
| abstract_inverted_index.(DIC), | 36 |
| abstract_inverted_index.Future | 204 |
| abstract_inverted_index.PRISMA | 98 |
| abstract_inverted_index.abrupt | 199 |
| abstract_inverted_index.debris | 23 |
| abstract_inverted_index.period | 138 |
| abstract_inverted_index.poorly | 56 |
| abstract_inverted_index.review | 68, 94 |
| abstract_inverted_index.single | 150 |
| abstract_inverted_index.sudden | 16, 140 |
| abstract_inverted_index.Content | 66 |
| abstract_inverted_index.Despite | 40 |
| abstract_inverted_index.Outlook | 186 |
| abstract_inverted_index.Summary | 128 |
| abstract_inverted_index.current | 74 |
| abstract_inverted_index.exists. | 154 |
| abstract_inverted_index.improve | 225 |
| abstract_inverted_index.include | 206 |
| abstract_inverted_index.regimen | 175 |
| abstract_inverted_index.remains | 45 |
| abstract_inverted_index.Abstract | 0 |
| abstract_inverted_index.Amniotic | 2 |
| abstract_inverted_index.Clinical | 111 |
| abstract_inverted_index.Embolism | 4 |
| abstract_inverted_index.Emerging | 169 |
| abstract_inverted_index.amniotic | 19 |
| abstract_inverted_index.articles | 102 |
| abstract_inverted_index.clinical | 84, 104 |
| abstract_inverted_index.critical | 193 |
| abstract_inverted_index.evidence | 124 |
| abstract_inverted_index.factors, | 83 |
| abstract_inverted_index.failure. | 39 |
| abstract_inverted_index.focusing | 159 |
| abstract_inverted_index.hypoxia, | 141 |
| abstract_inverted_index.maternal | 26, 50, 226 |
| abstract_inverted_index.neonatal | 228 |
| abstract_inverted_index.presents | 131 |
| abstract_inverted_index.provides | 69 |
| abstract_inverted_index.response | 222 |
| abstract_inverted_index.thematic | 126 |
| abstract_inverted_index.triggers | 29 |
| abstract_inverted_index.vascular | 64 |
| abstract_inverted_index.Diagnosis | 145 |
| abstract_inverted_index.analysis. | 127 |
| abstract_inverted_index.biomarker | 152 |
| abstract_inverted_index.challenge | 190 |
| abstract_inverted_index.clinical, | 147 |
| abstract_inverted_index.collapse, | 32 |
| abstract_inverted_index.conducted | 96 |
| abstract_inverted_index.continues | 188 |
| abstract_inverted_index.currently | 153 |
| abstract_inverted_index.developed | 121 |
| abstract_inverted_index.discussed | 180 |
| abstract_inverted_index.emergency | 12 |
| abstract_inverted_index.examining | 78 |
| abstract_inverted_index.fatality. | 203 |
| abstract_inverted_index.following | 97 |
| abstract_inverted_index.immediate | 136 |
| abstract_inverted_index.involving | 58 |
| abstract_inverted_index.knowledge | 75 |
| abstract_inverted_index.mortality | 51 |
| abstract_inverted_index.obstetric | 11, 191 |
| abstract_inverted_index.outcomes. | 229 |
| abstract_inverted_index.primarily | 157 |
| abstract_inverted_index.protocols | 105, 223 |
| abstract_inverted_index.published | 106 |
| abstract_inverted_index.reactions | 61 |
| abstract_inverted_index.synthesis | 72 |
| abstract_inverted_index.typically | 130 |
| abstract_inverted_index.validated | 210 |
| abstract_inverted_index.(Atropine, | 176 |
| abstract_inverted_index.Ketorolac) | 178 |
| abstract_inverted_index.Management | 155 |
| abstract_inverted_index.aggregated | 123 |
| abstract_inverted_index.aggressive | 166 |
| abstract_inverted_index.algorithms | 116 |
| abstract_inverted_index.approaches | 183 |
| abstract_inverted_index.diagnostic | 86, 115, 211 |
| abstract_inverted_index.frameworks | 119 |
| abstract_inverted_index.incidence, | 43 |
| abstract_inverted_index.literature | 93 |
| abstract_inverted_index.management | 89 |
| abstract_inverted_index.mechanical | 63 |
| abstract_inverted_index.postpartum | 137 |
| abstract_inverted_index.priorities | 205 |
| abstract_inverted_index.refinement | 213 |
| abstract_inverted_index.strategies | 170 |
| abstract_inverted_index.systematic | 92 |
| abstract_inverted_index.worldwide. | 52 |
| abstract_inverted_index.biomarkers, | 212 |
| abstract_inverted_index.challenges, | 87 |
| abstract_inverted_index.coagulation | 35 |
| abstract_inverted_index.contributor | 48 |
| abstract_inverted_index.correction. | 168 |
| abstract_inverted_index.development | 208 |
| abstract_inverted_index.guidelines, | 99 |
| abstract_inverted_index.hemodynamic | 163 |
| abstract_inverted_index.intrapartum | 132 |
| abstract_inverted_index.multi-organ | 38 |
| abstract_inverted_index.significant | 47 |
| abstract_inverted_index.strategies. | 90 |
| abstract_inverted_index.supportive, | 158 |
| abstract_inverted_index.therapeutic | 215 |
| abstract_inverted_index.understood, | 57 |
| abstract_inverted_index.Introduction | 1 |
| abstract_inverted_index.Ondansetron, | 177 |
| abstract_inverted_index.catastrophic | 10 |
| abstract_inverted_index.circulation. | 27 |
| abstract_inverted_index.coagulopathy | 167 |
| abstract_inverted_index.confirmatory | 151 |
| abstract_inverted_index.disseminated | 33 |
| abstract_inverted_index.hypotension, | 142 |
| abstract_inverted_index.obstruction. | 65 |
| abstract_inverted_index.standardized | 220 |
| abstract_inverted_index.anaphylactoid | 60 |
| abstract_inverted_index.characterized | 13 |
| abstract_inverted_index.coagulopathy. | 144 |
| abstract_inverted_index.comprehensive | 71 |
| abstract_inverted_index.epidemiology, | 80 |
| abstract_inverted_index.establishment | 218 |
| abstract_inverted_index.incorporating | 100 |
| abstract_inverted_index.intravascular | 34 |
| abstract_inverted_index.peer-reviewed | 101 |
| abstract_inverted_index.resuscitation | 118 |
| abstract_inverted_index.consideration. | 185 |
| abstract_inverted_index.interventions, | 216 |
| abstract_inverted_index.resuscitation, | 162 |
| abstract_inverted_index.stabilization, | 164 |
| abstract_inverted_index.cardiopulmonary | 31 |
| abstract_inverted_index.immune-mediated | 59 |
| abstract_inverted_index.investigational | 182 |
| abstract_inverted_index.manifestations, | 85 |
| abstract_inverted_index.pathophysiology | 54 |
| abstract_inverted_index.pathophysiology, | 81 |
| abstract_inverted_index.multidisciplinary | 221 |
| cited_by_percentile_year | |
| countries_distinct_count | 3 |
| institutions_distinct_count | 8 |
| citation_normalized_percentile.value | 0.41013387 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | True |