Exploring foci of:
bioRxiv (Cold Spring Harbor Laboratory)
An algorithmic procedure for measuring deep brain stimulation-induced capsular activation using motor evoked potentials
August 2025 • Eric R. Cole, Enrico Opri, Seyyed Bahram Borgheai, Han Yu-ji, Faiçal Isbaine, Nicholas M. Boulis, Jon T. Willie, Nicholas Au Yong, Robert E. Gross, S…
Abstract Objective Effective deep brain stimulation (DBS) treatment for Parkinson’s disease requires careful adjustment of stimulation parameters and targeting to avoid motor side effects caused by activation of the internal capsule. Currently, patients must self-report side effects during device programming and implantation surgery – a challenging and subjective process that could lead to suboptimal therapy or exacerbate the time needed to optimize treatment. Motor evoked potentials (mEP), the use of electromyogr…
Transcutaneous Electrical Nerve Stimulation
Neuroscience
Computer Science
Physical Medicine And Rehabilitation
Medicine
Internal Medicine
Parkinson's Disease
Disease