An evolving supraclavicular plaque: diagnostic challenges in dermatofibrosarcoma protuberans with atrophic and myxoid features Article Swipe
Maha Kazmi
,
Ayan Kusari
,
Anna Haemel
,
Philip E. LeBoit
,
Siegrid S. Yu
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.5070/d331365359
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.5070/d331365359
Dermatofibrosarcoma protuberans is an uncommon locally aggressive mesenchymal neoplasm that classically presents with a proliferation of monomorphic spindled cells with thin nuclei and scant cytoplasm. We report a man in his twenties who presented for an unrelated skin concern and was incidentally noted to have a large, atrophic scar-like depression of the left supraclavicular neck and shoulder. The plaque was photographed and the patient was instructed to follow-up in one year, and careful photo comparison revealed the lesion had subtly enlarged and darkened in color. Accordingly, a punch biopsy revealed features of myxoid dermatofibrosarcoma protuberans, a dermal proliferation of spindled cells with mucinous degeneration and more cellular areas with extensive nuclear palisading resembling the Verocay bodies of a neurofibroma. Clinicians should be aware of the broad clinicopathologic spectrum of DFSP to ensure timely diagnosis and effective treatment. Myxoid dermatofibrosarcoma protuberans is a rare and clinically challenging diagnosis, as the mucinous areas can impart a bluish hue. Dermatofibrosarcoma protuberans can also be atrophic, with the loss of the normal dermal thickness corresponding to a clinical appearance easily mistaken for anetoderma or atrophic scar. Palisaded nuclei resembling the Verocay bodies of schwannoma are sometimes seen and can further obfuscate the diagnosis.
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- Language
- en
- Landing Page
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- https://escholarship.org/content/qt4818z4jr/qt4818z4jr.pdf
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All OpenAlex metadata
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- DOI
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https://doi.org/10.5070/d331365359Digital Object Identifier
- Title
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An evolving supraclavicular plaque: diagnostic challenges in dermatofibrosarcoma protuberans with atrophic and myxoid featuresWork title
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articleOpenAlex work type
- Language
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enPrimary language
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2025Year of publication
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2025-06-17Full publication date if available
- Authors
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Maha Kazmi, Ayan Kusari, Anna Haemel, Philip E. LeBoit, Siegrid S. YuList of authors in order
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https://doi.org/10.5070/d331365359Publisher landing page
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https://escholarship.org/content/qt4818z4jr/qt4818z4jr.pdfDirect link to full text PDF
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YesWhether a free full text is available
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goldOpen access status per OpenAlex
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https://escholarship.org/content/qt4818z4jr/qt4818z4jr.pdfDirect OA link when available
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Medicine, Dermatofibrosarcoma protuberans, Dermatology, RadiologyTop concepts (fields/topics) attached by OpenAlex
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0Total citation count in OpenAlex
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10Other works algorithmically related by OpenAlex
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| abstract_inverted_index.follow-up | 67 |
| abstract_inverted_index.obfuscate | 196 |
| abstract_inverted_index.presented | 33 |
| abstract_inverted_index.scar-like | 48 |
| abstract_inverted_index.shoulder. | 56 |
| abstract_inverted_index.sometimes | 191 |
| abstract_inverted_index.thickness | 169 |
| abstract_inverted_index.unrelated | 36 |
| abstract_inverted_index.Clinicians | 119 |
| abstract_inverted_index.aggressive | 6 |
| abstract_inverted_index.anetoderma | 178 |
| abstract_inverted_index.appearance | 174 |
| abstract_inverted_index.clinically | 144 |
| abstract_inverted_index.comparison | 74 |
| abstract_inverted_index.cytoplasm. | 24 |
| abstract_inverted_index.depression | 49 |
| abstract_inverted_index.diagnosis, | 146 |
| abstract_inverted_index.diagnosis. | 198 |
| abstract_inverted_index.instructed | 65 |
| abstract_inverted_index.palisading | 111 |
| abstract_inverted_index.resembling | 112, 184 |
| abstract_inverted_index.schwannoma | 189 |
| abstract_inverted_index.treatment. | 136 |
| abstract_inverted_index.challenging | 145 |
| abstract_inverted_index.classically | 10 |
| abstract_inverted_index.mesenchymal | 7 |
| abstract_inverted_index.monomorphic | 16 |
| abstract_inverted_index.protuberans | 1, 139, 157 |
| abstract_inverted_index.Accordingly, | 85 |
| abstract_inverted_index.degeneration | 103 |
| abstract_inverted_index.incidentally | 41 |
| abstract_inverted_index.photographed | 60 |
| abstract_inverted_index.protuberans, | 94 |
| abstract_inverted_index.corresponding | 170 |
| abstract_inverted_index.neurofibroma. | 118 |
| abstract_inverted_index.proliferation | 14, 97 |
| abstract_inverted_index.supraclavicular | 53 |
| abstract_inverted_index.clinicopathologic | 126 |
| abstract_inverted_index.Dermatofibrosarcoma | 0, 156 |
| abstract_inverted_index.dermatofibrosarcoma | 93, 138 |
| cited_by_percentile_year | |
| countries_distinct_count | 1 |
| institutions_distinct_count | 5 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/2 |
| sustainable_development_goals[0].score | 0.4000000059604645 |
| sustainable_development_goals[0].display_name | Zero hunger |
| citation_normalized_percentile.value | 0.36277507 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |