Analysis of nutritional effects and other risk factors for the development of postoperative delirium in patients undergoing coronary arterial bypass grafting: A retrospective secondary analysis Article Swipe
Background: Delirium is an acute brain dysfunction associated with increased mortality, morbidity, and long-term cognitive dysfunction. Studies showed that the incidence of post-cardiac surgery delirium (PCSD) might reach up to 70% of patients. This study aims to analyze risk factors contributing to the incidence of PCSD in patients undergoing elective cardiac surgeries. Methods: This study is a secondary retrospective cohort analysis that utilizes prospectively collected data from an 8-year follow-up period to investigate the nutritional status of patients undergoing cardiac surgery. Data from 1187 patients was analyzed for risk factors associated with PCSD. The statistical analysis was conducted using R version 4.2.0. A p-value less than 0.05 was considered statistically significant. Results: A total of 1,187 patients were included in our analysis based on the dataset. The prevalence of delirium in the sample set was 8% (96/1187). Each parameter underwent univariate analysis, and significant parameters were included in a multivariate logistic regression model. The analysis revealed that parameters like increasing age at p< 0.05, with an odds ratio (OR) of 1.05, CI (1.02 -1.07), the aortic cross-clamp time (p<0.05) with an OR=1.01 CI [1.01-1.02], longer ventilation hours (p<0.05) with an OR= 1.06 CI [1.02-1.10], hospital and intensive care length of stay with p<0.05 and, p<0.001, respectively to be associated with increased incidence of postoperative delirium. Conclusion: There is a significant association between PCSD and various factors such as advanced age, extended duration of aortic cross-clamp, prolonged mechanical ventilation, and increased length of hospitalization in patients undergoing cardiac surgeries.
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Metadata
- Type
- preprint
- Language
- en
- Landing Page
- https://doi.org/10.21203/rs.3.rs-4236528/v1
- OA Status
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All OpenAlex metadata
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- OpenAlex ID
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https://openalex.org/W4400117202Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.21203/rs.3.rs-4236528/v1Digital Object Identifier
- Title
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Analysis of nutritional effects and other risk factors for the development of postoperative delirium in patients undergoing coronary arterial bypass grafting: A retrospective secondary analysisWork title
- Type
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preprintOpenAlex work type
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enPrimary language
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2024Year of publication
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2024-06-28Full publication date if available
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Ahmed OmranList of authors in order
- Landing page
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https://doi.org/10.21203/rs.3.rs-4236528/v1Publisher landing page
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YesWhether a free full text is available
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goldOpen access status per OpenAlex
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https://doi.org/10.21203/rs.3.rs-4236528/v1Direct OA link when available
- Concepts
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Bypass grafting, Delirium, Medicine, Artery, Grafting, Retrospective cohort study, Internal medicine, Cardiology, Surgery, Intensive care medicine, Chemistry, Polymer, Organic chemistryTop concepts (fields/topics) attached by OpenAlex
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0Total citation count in OpenAlex
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19Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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| sustainable_development_goals[0].id | https://metadata.un.org/sdg/2 |
| sustainable_development_goals[0].score | 0.6800000071525574 |
| sustainable_development_goals[0].display_name | Zero hunger |
| citation_normalized_percentile.value | 0.14772269 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |