Analysis of the Level of Adiponectin and Selected Cytokines in Patients with Knee Osteoarthritis Article Swipe
Iosif Ilia
,
Paula Diana Ciordas
,
Diana Nițușcă
,
Alina Anton
,
Cătălin Marian
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.3390/medicina60040571
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.3390/medicina60040571
Background and Objectives: Knee osteoarthritis (KOA) is a degenerative disease that is continuously targeting people of different ages, but especially the elderly population, the number of which tends to increase continuously at the global level. Apart from age, excess weight can influence the evolution of the disease, with obesity being associated with a weak inflammation stage and an imbalance between pro-inflammatory and anti-inflammatory cytokines. The present work aimed to analyze specific biomarkers, namely ACRP-30, IL-10, TNF-α, and IL-6, in knee synovial fluid, and correlate them with KOA patients’ clinical data, radiographic changes, and functional and pain scores. Materials and Methods: 24 subjects with KOA and over 50 years of age participate in the present study. Synovial fluid was harvested using ultrasound guidance from the target knees of the enrolled KOA patients, and the levels of ACRP-30, IL-10, TNF-α, and IL-6 were measured using enzyme-linked immunosorbent assays (ELISA). All patients underwent a supine X-ray at the target knee and were classified using Kellgren–Lawrence (K–L) grading. The Western Ontario and McMaster University Osteoarthritis Index (WOMAC) was used to assess self-reported physical function, pain, and stiffness. Results: The obtained results highlighted a significant correlation between age and adiponectin level (p = 0.0451, r = −0.412). Also, the IL-10 values are lower in cases where the intensity of the pain is more pronounced (p = 0.0405, r = −0.421). In addition, analyzing the data by gender, it was observed that in the case of males, stiffness is more related to age (p = 0.0079, r = 0.7993), compared to women (p = 0.0203, r = 0.6223). In the case of women, the progression of the disease tends to increase more intensively the WOMAC score’s total values (p = 0.00031, r = 0.8342), compared with men (p = 0.0289, r = 7013). Regarding interleukins and BMI, significant correlations were observed only in the case of men. Conclusions: A significant correlation between age and adiponectin, and adiponectin and IL-6, suggests that advanced age may contribute to adiponectin reduction. Comparing men with women, it was observed that men’s age is more related to rigidity, and IL-6 and IL-10 are directly correlated to BMI; in addition, women seem to be more sensitive to pain and stiffness.
Related Topics
Concepts
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.3390/medicina60040571
- https://www.mdpi.com/1648-9144/60/4/571/pdf?version=1711788856
- OA Status
- gold
- Cited By
- 6
- References
- 54
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4393357784
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4393357784Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.3390/medicina60040571Digital Object Identifier
- Title
-
Analysis of the Level of Adiponectin and Selected Cytokines in Patients with Knee OsteoarthritisWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2024Year of publication
- Publication date
-
2024-03-30Full publication date if available
- Authors
-
Iosif Ilia, Paula Diana Ciordas, Diana Nițușcă, Alina Anton, Cătălin MarianList of authors in order
- Landing page
-
https://doi.org/10.3390/medicina60040571Publisher landing page
- PDF URL
-
https://www.mdpi.com/1648-9144/60/4/571/pdf?version=1711788856Direct link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
-
https://www.mdpi.com/1648-9144/60/4/571/pdf?version=1711788856Direct OA link when available
- Concepts
-
Adiponectin, Osteoarthritis, Medicine, Internal medicine, Obesity, Pathology, Insulin resistance, Alternative medicineTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
6Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 4, 2024: 2Per-year citation counts (last 5 years)
- References (count)
-
54Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W4393357784 |
|---|---|
| doi | https://doi.org/10.3390/medicina60040571 |
| ids.doi | https://doi.org/10.3390/medicina60040571 |
| ids.pmid | https://pubmed.ncbi.nlm.nih.gov/38674217 |
| ids.openalex | https://openalex.org/W4393357784 |
| fwci | 6.29674943 |
| mesh[0].qualifier_ui | |
| mesh[0].descriptor_ui | D006801 |
| mesh[0].is_major_topic | False |
| mesh[0].qualifier_name | |
| mesh[0].descriptor_name | Humans |
| mesh[1].qualifier_ui | Q000097 |
| mesh[1].descriptor_ui | D020370 |
| mesh[1].is_major_topic | True |
| mesh[1].qualifier_name | blood |
| mesh[1].descriptor_name | Osteoarthritis, Knee |
| mesh[2].qualifier_ui | Q000000981 |
| mesh[2].descriptor_ui | D020370 |
| mesh[2].is_major_topic | True |
| mesh[2].qualifier_name | diagnostic imaging |
| mesh[2].descriptor_name | Osteoarthritis, Knee |
| mesh[3].qualifier_ui | |
| mesh[3].descriptor_ui | D008297 |
| mesh[3].is_major_topic | False |
| mesh[3].qualifier_name | |
| mesh[3].descriptor_name | Male |
| mesh[4].qualifier_ui | |
| mesh[4].descriptor_ui | D005260 |
| mesh[4].is_major_topic | False |
| mesh[4].qualifier_name | |
| mesh[4].descriptor_name | Female |
| mesh[5].qualifier_ui | |
| mesh[5].descriptor_ui | D008875 |
| mesh[5].is_major_topic | False |
| mesh[5].qualifier_name | |
| mesh[5].descriptor_name | Middle Aged |
| mesh[6].qualifier_ui | Q000097 |
| mesh[6].descriptor_ui | D052242 |
| mesh[6].is_major_topic | True |
| mesh[6].qualifier_name | blood |
| mesh[6].descriptor_name | Adiponectin |
| mesh[7].qualifier_ui | Q000032 |
| mesh[7].descriptor_ui | D052242 |
| mesh[7].is_major_topic | True |
| mesh[7].qualifier_name | analysis |
| mesh[7].descriptor_name | Adiponectin |
| mesh[8].qualifier_ui | |
| mesh[8].descriptor_ui | D000368 |
| mesh[8].is_major_topic | False |
| mesh[8].qualifier_name | |
| mesh[8].descriptor_name | Aged |
| mesh[9].qualifier_ui | Q000097 |
| mesh[9].descriptor_ui | D016207 |
| mesh[9].is_major_topic | True |
| mesh[9].qualifier_name | blood |
| mesh[9].descriptor_name | Cytokines |
| mesh[10].qualifier_ui | Q000032 |
| mesh[10].descriptor_ui | D016207 |
| mesh[10].is_major_topic | True |
| mesh[10].qualifier_name | analysis |
| mesh[10].descriptor_name | Cytokines |
| mesh[11].qualifier_ui | Q000032 |
| mesh[11].descriptor_ui | D015415 |
| mesh[11].is_major_topic | True |
| mesh[11].qualifier_name | analysis |
| mesh[11].descriptor_name | Biomarkers |
| mesh[12].qualifier_ui | Q000097 |
| mesh[12].descriptor_ui | D015415 |
| mesh[12].is_major_topic | True |
| mesh[12].qualifier_name | blood |
| mesh[12].descriptor_name | Biomarkers |
| mesh[13].qualifier_ui | Q000097 |
| mesh[13].descriptor_ui | D016753 |
| mesh[13].is_major_topic | True |
| mesh[13].qualifier_name | blood |
| mesh[13].descriptor_name | Interleukin-10 |
| mesh[14].qualifier_ui | Q000032 |
| mesh[14].descriptor_ui | D016753 |
| mesh[14].is_major_topic | True |
| mesh[14].qualifier_name | analysis |
| mesh[14].descriptor_name | Interleukin-10 |
| mesh[15].qualifier_ui | Q000032 |
| mesh[15].descriptor_ui | D014409 |
| mesh[15].is_major_topic | True |
| mesh[15].qualifier_name | analysis |
| mesh[15].descriptor_name | Tumor Necrosis Factor-alpha |
| mesh[16].qualifier_ui | Q000097 |
| mesh[16].descriptor_ui | D014409 |
| mesh[16].is_major_topic | True |
| mesh[16].qualifier_name | blood |
| mesh[16].descriptor_name | Tumor Necrosis Factor-alpha |
| mesh[17].qualifier_ui | Q000097 |
| mesh[17].descriptor_ui | D015850 |
| mesh[17].is_major_topic | False |
| mesh[17].qualifier_name | blood |
| mesh[17].descriptor_name | Interleukin-6 |
| mesh[18].qualifier_ui | Q000032 |
| mesh[18].descriptor_ui | D015850 |
| mesh[18].is_major_topic | False |
| mesh[18].qualifier_name | analysis |
| mesh[18].descriptor_name | Interleukin-6 |
| mesh[19].qualifier_ui | Q000737 |
| mesh[19].descriptor_ui | D013582 |
| mesh[19].is_major_topic | False |
| mesh[19].qualifier_name | chemistry |
| mesh[19].descriptor_name | Synovial Fluid |
| mesh[20].qualifier_ui | Q000378 |
| mesh[20].descriptor_ui | D013582 |
| mesh[20].is_major_topic | False |
| mesh[20].qualifier_name | metabolism |
| mesh[20].descriptor_name | Synovial Fluid |
| mesh[21].qualifier_ui | |
| mesh[21].descriptor_ui | D004797 |
| mesh[21].is_major_topic | False |
| mesh[21].qualifier_name | |
| mesh[21].descriptor_name | Enzyme-Linked Immunosorbent Assay |
| mesh[22].qualifier_ui | |
| mesh[22].descriptor_ui | D006801 |
| mesh[22].is_major_topic | False |
| mesh[22].qualifier_name | |
| mesh[22].descriptor_name | Humans |
| mesh[23].qualifier_ui | Q000097 |
| mesh[23].descriptor_ui | D020370 |
| mesh[23].is_major_topic | True |
| mesh[23].qualifier_name | blood |
| mesh[23].descriptor_name | Osteoarthritis, Knee |
| mesh[24].qualifier_ui | Q000000981 |
| mesh[24].descriptor_ui | D020370 |
| mesh[24].is_major_topic | True |
| mesh[24].qualifier_name | diagnostic imaging |
| mesh[24].descriptor_name | Osteoarthritis, Knee |
| mesh[25].qualifier_ui | |
| mesh[25].descriptor_ui | D008297 |
| mesh[25].is_major_topic | False |
| mesh[25].qualifier_name | |
| mesh[25].descriptor_name | Male |
| mesh[26].qualifier_ui | |
| mesh[26].descriptor_ui | D005260 |
| mesh[26].is_major_topic | False |
| mesh[26].qualifier_name | |
| mesh[26].descriptor_name | Female |
| mesh[27].qualifier_ui | |
| mesh[27].descriptor_ui | D008875 |
| mesh[27].is_major_topic | False |
| mesh[27].qualifier_name | |
| mesh[27].descriptor_name | Middle Aged |
| mesh[28].qualifier_ui | Q000097 |
| mesh[28].descriptor_ui | D052242 |
| mesh[28].is_major_topic | True |
| mesh[28].qualifier_name | blood |
| mesh[28].descriptor_name | Adiponectin |
| mesh[29].qualifier_ui | Q000032 |
| mesh[29].descriptor_ui | D052242 |
| mesh[29].is_major_topic | True |
| mesh[29].qualifier_name | analysis |
| mesh[29].descriptor_name | Adiponectin |
| mesh[30].qualifier_ui | |
| mesh[30].descriptor_ui | D000368 |
| mesh[30].is_major_topic | False |
| mesh[30].qualifier_name | |
| mesh[30].descriptor_name | Aged |
| mesh[31].qualifier_ui | Q000097 |
| mesh[31].descriptor_ui | D016207 |
| mesh[31].is_major_topic | True |
| mesh[31].qualifier_name | blood |
| mesh[31].descriptor_name | Cytokines |
| mesh[32].qualifier_ui | Q000032 |
| mesh[32].descriptor_ui | D016207 |
| mesh[32].is_major_topic | True |
| mesh[32].qualifier_name | analysis |
| mesh[32].descriptor_name | Cytokines |
| mesh[33].qualifier_ui | Q000032 |
| mesh[33].descriptor_ui | D015415 |
| mesh[33].is_major_topic | True |
| mesh[33].qualifier_name | analysis |
| mesh[33].descriptor_name | Biomarkers |
| mesh[34].qualifier_ui | Q000097 |
| mesh[34].descriptor_ui | D015415 |
| mesh[34].is_major_topic | True |
| mesh[34].qualifier_name | blood |
| mesh[34].descriptor_name | Biomarkers |
| mesh[35].qualifier_ui | Q000097 |
| mesh[35].descriptor_ui | D016753 |
| mesh[35].is_major_topic | True |
| mesh[35].qualifier_name | blood |
| mesh[35].descriptor_name | Interleukin-10 |
| mesh[36].qualifier_ui | Q000032 |
| mesh[36].descriptor_ui | D016753 |
| mesh[36].is_major_topic | True |
| mesh[36].qualifier_name | analysis |
| mesh[36].descriptor_name | Interleukin-10 |
| mesh[37].qualifier_ui | Q000032 |
| mesh[37].descriptor_ui | D014409 |
| mesh[37].is_major_topic | True |
| mesh[37].qualifier_name | analysis |
| mesh[37].descriptor_name | Tumor Necrosis Factor-alpha |
| mesh[38].qualifier_ui | Q000097 |
| mesh[38].descriptor_ui | D014409 |
| mesh[38].is_major_topic | True |
| mesh[38].qualifier_name | blood |
| mesh[38].descriptor_name | Tumor Necrosis Factor-alpha |
| mesh[39].qualifier_ui | Q000097 |
| mesh[39].descriptor_ui | D015850 |
| mesh[39].is_major_topic | False |
| mesh[39].qualifier_name | blood |
| mesh[39].descriptor_name | Interleukin-6 |
| mesh[40].qualifier_ui | Q000032 |
| mesh[40].descriptor_ui | D015850 |
| mesh[40].is_major_topic | False |
| mesh[40].qualifier_name | analysis |
| mesh[40].descriptor_name | Interleukin-6 |
| mesh[41].qualifier_ui | Q000737 |
| mesh[41].descriptor_ui | D013582 |
| mesh[41].is_major_topic | False |
| mesh[41].qualifier_name | chemistry |
| mesh[41].descriptor_name | Synovial Fluid |
| mesh[42].qualifier_ui | Q000378 |
| mesh[42].descriptor_ui | D013582 |
| mesh[42].is_major_topic | False |
| mesh[42].qualifier_name | metabolism |
| mesh[42].descriptor_name | Synovial Fluid |
| mesh[43].qualifier_ui | |
| mesh[43].descriptor_ui | D004797 |
| mesh[43].is_major_topic | False |
| mesh[43].qualifier_name | |
| mesh[43].descriptor_name | Enzyme-Linked Immunosorbent Assay |
| mesh[44].qualifier_ui | |
| mesh[44].descriptor_ui | D006801 |
| mesh[44].is_major_topic | False |
| mesh[44].qualifier_name | |
| mesh[44].descriptor_name | Humans |
| mesh[45].qualifier_ui | Q000097 |
| mesh[45].descriptor_ui | D020370 |
| mesh[45].is_major_topic | True |
| mesh[45].qualifier_name | blood |
| mesh[45].descriptor_name | Osteoarthritis, Knee |
| mesh[46].qualifier_ui | Q000000981 |
| mesh[46].descriptor_ui | D020370 |
| mesh[46].is_major_topic | True |
| mesh[46].qualifier_name | diagnostic imaging |
| mesh[46].descriptor_name | Osteoarthritis, Knee |
| mesh[47].qualifier_ui | |
| mesh[47].descriptor_ui | D008297 |
| mesh[47].is_major_topic | False |
| mesh[47].qualifier_name | |
| mesh[47].descriptor_name | Male |
| mesh[48].qualifier_ui | |
| mesh[48].descriptor_ui | D005260 |
| mesh[48].is_major_topic | False |
| mesh[48].qualifier_name | |
| mesh[48].descriptor_name | Female |
| mesh[49].qualifier_ui | |
| mesh[49].descriptor_ui | D008875 |
| mesh[49].is_major_topic | False |
| mesh[49].qualifier_name | |
| mesh[49].descriptor_name | Middle Aged |
| type | article |
| title | Analysis of the Level of Adiponectin and Selected Cytokines in Patients with Knee Osteoarthritis |
| biblio.issue | 4 |
| biblio.volume | 60 |
| biblio.last_page | 571 |
| biblio.first_page | 571 |
| topics[0].id | https://openalex.org/T10105 |
| topics[0].field.id | https://openalex.org/fields/27 |
| topics[0].field.display_name | Medicine |
| topics[0].score | 0.9993000030517578 |
| topics[0].domain.id | https://openalex.org/domains/4 |
| topics[0].domain.display_name | Health Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/2745 |
| topics[0].subfield.display_name | Rheumatology |
| topics[0].display_name | Osteoarthritis Treatment and Mechanisms |
| topics[1].id | https://openalex.org/T10528 |
| topics[1].field.id | https://openalex.org/fields/27 |
| topics[1].field.display_name | Medicine |
| topics[1].score | 0.994700014591217 |
| topics[1].domain.id | https://openalex.org/domains/4 |
| topics[1].domain.display_name | Health Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/2713 |
| topics[1].subfield.display_name | Epidemiology |
| topics[1].display_name | Adipokines, Inflammation, and Metabolic Diseases |
| topics[2].id | https://openalex.org/T11532 |
| topics[2].field.id | https://openalex.org/fields/27 |
| topics[2].field.display_name | Medicine |
| topics[2].score | 0.9787999987602234 |
| topics[2].domain.id | https://openalex.org/domains/4 |
| topics[2].domain.display_name | Health Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/2730 |
| topics[2].subfield.display_name | Oncology |
| topics[2].display_name | Chemokine receptors and signaling |
| is_xpac | False |
| apc_list.value | 1800 |
| apc_list.currency | CHF |
| apc_list.value_usd | 1949 |
| apc_paid.value | 1800 |
| apc_paid.currency | CHF |
| apc_paid.value_usd | 1949 |
| concepts[0].id | https://openalex.org/C2776782570 |
| concepts[0].level | 4 |
| concepts[0].score | 0.9210572242736816 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q357439 |
| concepts[0].display_name | Adiponectin |
| concepts[1].id | https://openalex.org/C2776164576 |
| concepts[1].level | 3 |
| concepts[1].score | 0.8121634721755981 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q62736 |
| concepts[1].display_name | Osteoarthritis |
| concepts[2].id | https://openalex.org/C71924100 |
| concepts[2].level | 0 |
| concepts[2].score | 0.5581997632980347 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q11190 |
| concepts[2].display_name | Medicine |
| concepts[3].id | https://openalex.org/C126322002 |
| concepts[3].level | 1 |
| concepts[3].score | 0.4674464464187622 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q11180 |
| concepts[3].display_name | Internal medicine |
| concepts[4].id | https://openalex.org/C511355011 |
| concepts[4].level | 2 |
| concepts[4].score | 0.11944794654846191 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q12174 |
| concepts[4].display_name | Obesity |
| concepts[5].id | https://openalex.org/C142724271 |
| concepts[5].level | 1 |
| concepts[5].score | 0.11074095964431763 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q7208 |
| concepts[5].display_name | Pathology |
| concepts[6].id | https://openalex.org/C2777391703 |
| concepts[6].level | 3 |
| concepts[6].score | 0.03561297059059143 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q1053470 |
| concepts[6].display_name | Insulin resistance |
| concepts[7].id | https://openalex.org/C204787440 |
| concepts[7].level | 2 |
| concepts[7].score | 0.0 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q188504 |
| concepts[7].display_name | Alternative medicine |
| keywords[0].id | https://openalex.org/keywords/adiponectin |
| keywords[0].score | 0.9210572242736816 |
| keywords[0].display_name | Adiponectin |
| keywords[1].id | https://openalex.org/keywords/osteoarthritis |
| keywords[1].score | 0.8121634721755981 |
| keywords[1].display_name | Osteoarthritis |
| keywords[2].id | https://openalex.org/keywords/medicine |
| keywords[2].score | 0.5581997632980347 |
| keywords[2].display_name | Medicine |
| keywords[3].id | https://openalex.org/keywords/internal-medicine |
| keywords[3].score | 0.4674464464187622 |
| keywords[3].display_name | Internal medicine |
| keywords[4].id | https://openalex.org/keywords/obesity |
| keywords[4].score | 0.11944794654846191 |
| keywords[4].display_name | Obesity |
| keywords[5].id | https://openalex.org/keywords/pathology |
| keywords[5].score | 0.11074095964431763 |
| keywords[5].display_name | Pathology |
| keywords[6].id | https://openalex.org/keywords/insulin-resistance |
| keywords[6].score | 0.03561297059059143 |
| keywords[6].display_name | Insulin resistance |
| language | en |
| locations[0].id | doi:10.3390/medicina60040571 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S1008817457 |
| locations[0].source.issn | 1010-660X, 1648-9144 |
| locations[0].source.type | journal |
| locations[0].source.is_oa | True |
| locations[0].source.issn_l | 1010-660X |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | True |
| locations[0].source.display_name | Medicina |
| locations[0].source.host_organization | https://openalex.org/P4310310987 |
| locations[0].source.host_organization_name | Multidisciplinary Digital Publishing Institute |
| locations[0].source.host_organization_lineage | https://openalex.org/P4310310987 |
| locations[0].source.host_organization_lineage_names | Multidisciplinary Digital Publishing Institute |
| locations[0].license | cc-by |
| locations[0].pdf_url | https://www.mdpi.com/1648-9144/60/4/571/pdf?version=1711788856 |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | https://openalex.org/licenses/cc-by |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | Medicina |
| locations[0].landing_page_url | https://doi.org/10.3390/medicina60040571 |
| locations[1].id | pmid:38674217 |
| locations[1].is_oa | False |
| locations[1].source.id | https://openalex.org/S4306525036 |
| locations[1].source.issn | |
| locations[1].source.type | repository |
| locations[1].source.is_oa | False |
| locations[1].source.issn_l | |
| locations[1].source.is_core | False |
| locations[1].source.is_in_doaj | False |
| locations[1].source.display_name | PubMed |
| locations[1].source.host_organization | https://openalex.org/I1299303238 |
| locations[1].source.host_organization_name | National Institutes of Health |
| locations[1].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[1].license | |
| locations[1].pdf_url | |
| locations[1].version | publishedVersion |
| locations[1].raw_type | |
| locations[1].license_id | |
| locations[1].is_accepted | True |
| locations[1].is_published | True |
| locations[1].raw_source_name | Medicina (Kaunas, Lithuania) |
| locations[1].landing_page_url | https://pubmed.ncbi.nlm.nih.gov/38674217 |
| locations[2].id | pmh:oai:doaj.org/article:cbd1dc3fefd34dac91d6abc70b49ca3d |
| locations[2].is_oa | False |
| locations[2].source.id | https://openalex.org/S4306401280 |
| locations[2].source.issn | |
| locations[2].source.type | repository |
| locations[2].source.is_oa | False |
| locations[2].source.issn_l | |
| locations[2].source.is_core | False |
| locations[2].source.is_in_doaj | False |
| locations[2].source.display_name | DOAJ (DOAJ: Directory of Open Access Journals) |
| locations[2].source.host_organization | |
| locations[2].source.host_organization_name | |
| locations[2].license | |
| locations[2].pdf_url | |
| locations[2].version | submittedVersion |
| locations[2].raw_type | article |
| locations[2].license_id | |
| locations[2].is_accepted | False |
| locations[2].is_published | False |
| locations[2].raw_source_name | Medicina, Vol 60, Iss 4, p 571 (2024) |
| locations[2].landing_page_url | https://doaj.org/article/cbd1dc3fefd34dac91d6abc70b49ca3d |
| locations[3].id | pmh:oai:pubmedcentral.nih.gov:11052232 |
| locations[3].is_oa | True |
| locations[3].source.id | https://openalex.org/S2764455111 |
| locations[3].source.issn | |
| locations[3].source.type | repository |
| locations[3].source.is_oa | False |
| locations[3].source.issn_l | |
| locations[3].source.is_core | False |
| locations[3].source.is_in_doaj | False |
| locations[3].source.display_name | PubMed Central |
| locations[3].source.host_organization | https://openalex.org/I1299303238 |
| locations[3].source.host_organization_name | National Institutes of Health |
| locations[3].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[3].license | other-oa |
| locations[3].pdf_url | |
| locations[3].version | submittedVersion |
| locations[3].raw_type | Text |
| locations[3].license_id | https://openalex.org/licenses/other-oa |
| locations[3].is_accepted | False |
| locations[3].is_published | False |
| locations[3].raw_source_name | Medicina (Kaunas) |
| locations[3].landing_page_url | https://www.ncbi.nlm.nih.gov/pmc/articles/11052232 |
| indexed_in | crossref, doaj, pubmed |
| authorships[0].author.id | https://openalex.org/A5007192208 |
| authorships[0].author.orcid | https://orcid.org/0000-0002-0036-239X |
| authorships[0].author.display_name | Iosif Ilia |
| authorships[0].countries | RO |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I4210088791 |
| authorships[0].affiliations[0].raw_affiliation_string | Discipline of Biochemistry, "Victor Babes" University of Medicine and Pharmacy, 300041 Timis , oara, Romania; |
| authorships[0].affiliations[1].institution_ids | https://openalex.org/I64956957 |
| authorships[0].affiliations[1].raw_affiliation_string | Faculty of Physical Education and Sport, Physical Activities Research Center, "Aurel Vlaicu" University of Arad, 310025 Arad, Romania |
| authorships[0].institutions[0].id | https://openalex.org/I64956957 |
| authorships[0].institutions[0].ror | https://ror.org/05w5rsy15 |
| authorships[0].institutions[0].type | education |
| authorships[0].institutions[0].lineage | https://openalex.org/I64956957 |
| authorships[0].institutions[0].country_code | RO |
| authorships[0].institutions[0].display_name | Aurel Vlaicu University of Arad |
| authorships[0].institutions[1].id | https://openalex.org/I4210088791 |
| authorships[0].institutions[1].ror | https://ror.org/00afdp487 |
| authorships[0].institutions[1].type | education |
| authorships[0].institutions[1].lineage | https://openalex.org/I4210088791 |
| authorships[0].institutions[1].country_code | RO |
| authorships[0].institutions[1].display_name | Victor Babeș University of Medicine and Pharmacy Timișoara |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Iosif Ilia |
| authorships[0].is_corresponding | False |
| authorships[0].raw_affiliation_strings | Discipline of Biochemistry, "Victor Babes" University of Medicine and Pharmacy, 300041 Timis , oara, Romania;, Faculty of Physical Education and Sport, Physical Activities Research Center, "Aurel Vlaicu" University of Arad, 310025 Arad, Romania |
| authorships[1].author.id | https://openalex.org/A5036914714 |
| authorships[1].author.orcid | |
| authorships[1].author.display_name | Paula Diana Ciordas |
| authorships[1].countries | RO |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I4210088791 |
| authorships[1].affiliations[0].raw_affiliation_string | Center for Complex Network Science, “Victor Babes” University of Medicine and Pharmacy, 300041 Timişoara, Romania |
| authorships[1].affiliations[1].institution_ids | https://openalex.org/I4210088791 |
| authorships[1].affiliations[1].raw_affiliation_string | Discipline of Biochemistry, "Victor Babes" University of Medicine and Pharmacy, 300041 Timis , oara, Romania; |
| authorships[1].institutions[0].id | https://openalex.org/I4210088791 |
| authorships[1].institutions[0].ror | https://ror.org/00afdp487 |
| authorships[1].institutions[0].type | education |
| authorships[1].institutions[0].lineage | https://openalex.org/I4210088791 |
| authorships[1].institutions[0].country_code | RO |
| authorships[1].institutions[0].display_name | Victor Babeș University of Medicine and Pharmacy Timișoara |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Paula Diana Ciordas |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | Center for Complex Network Science, “Victor Babes” University of Medicine and Pharmacy, 300041 Timişoara, Romania, Discipline of Biochemistry, "Victor Babes" University of Medicine and Pharmacy, 300041 Timis , oara, Romania; |
| authorships[2].author.id | https://openalex.org/A5033223698 |
| authorships[2].author.orcid | https://orcid.org/0000-0002-5325-5221 |
| authorships[2].author.display_name | Diana Nițușcă |
| authorships[2].countries | RO |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I4210088791 |
| authorships[2].affiliations[0].raw_affiliation_string | Center for Complex Network Science, “Victor Babes” University of Medicine and Pharmacy, 300041 Timişoara, Romania |
| authorships[2].affiliations[1].institution_ids | https://openalex.org/I4210088791 |
| authorships[2].affiliations[1].raw_affiliation_string | Discipline of Biochemistry, "Victor Babes" University of Medicine and Pharmacy, 300041 Timis , oara, Romania; |
| authorships[2].institutions[0].id | https://openalex.org/I4210088791 |
| authorships[2].institutions[0].ror | https://ror.org/00afdp487 |
| authorships[2].institutions[0].type | education |
| authorships[2].institutions[0].lineage | https://openalex.org/I4210088791 |
| authorships[2].institutions[0].country_code | RO |
| authorships[2].institutions[0].display_name | Victor Babeș University of Medicine and Pharmacy Timișoara |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Diana Nitusca |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | Center for Complex Network Science, “Victor Babes” University of Medicine and Pharmacy, 300041 Timişoara, Romania, Discipline of Biochemistry, "Victor Babes" University of Medicine and Pharmacy, 300041 Timis , oara, Romania; |
| authorships[3].author.id | https://openalex.org/A5062545153 |
| authorships[3].author.orcid | https://orcid.org/0000-0002-3818-5261 |
| authorships[3].author.display_name | Alina Anton |
| authorships[3].countries | RO |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I4210088791 |
| authorships[3].affiliations[0].raw_affiliation_string | Research Center for Pharmaco-Toxicological Evaluations, "Victor Babes" University of Medicine and Pharmacy Timisoara, Eftimie Murgu Sq. No. 2, 300041 Timisoara, Romania |
| authorships[3].affiliations[1].institution_ids | https://openalex.org/I4210088791 |
| authorships[3].affiliations[1].raw_affiliation_string | Department of Toxicology and Drug Industry, Faculty of Pharmacy, "Victor Babes" University of Medicine and Pharmacy Timisoara, Eftimie Murgu Sq. No. 2, 300041 Timisoara, Romania |
| authorships[3].institutions[0].id | https://openalex.org/I4210088791 |
| authorships[3].institutions[0].ror | https://ror.org/00afdp487 |
| authorships[3].institutions[0].type | education |
| authorships[3].institutions[0].lineage | https://openalex.org/I4210088791 |
| authorships[3].institutions[0].country_code | RO |
| authorships[3].institutions[0].display_name | Victor Babeș University of Medicine and Pharmacy Timișoara |
| authorships[3].author_position | middle |
| authorships[3].raw_author_name | Alina Anton |
| authorships[3].is_corresponding | False |
| authorships[3].raw_affiliation_strings | Department of Toxicology and Drug Industry, Faculty of Pharmacy, "Victor Babes" University of Medicine and Pharmacy Timisoara, Eftimie Murgu Sq. No. 2, 300041 Timisoara, Romania, Research Center for Pharmaco-Toxicological Evaluations, "Victor Babes" University of Medicine and Pharmacy Timisoara, Eftimie Murgu Sq. No. 2, 300041 Timisoara, Romania |
| authorships[4].author.id | https://openalex.org/A5079376711 |
| authorships[4].author.orcid | https://orcid.org/0000-0002-7749-1384 |
| authorships[4].author.display_name | Cătălin Marian |
| authorships[4].countries | RO |
| authorships[4].affiliations[0].institution_ids | https://openalex.org/I4210088791 |
| authorships[4].affiliations[0].raw_affiliation_string | Center for Complex Network Science, “Victor Babes” University of Medicine and Pharmacy, 300041 Timişoara, Romania |
| authorships[4].affiliations[1].institution_ids | https://openalex.org/I4210088791 |
| authorships[4].affiliations[1].raw_affiliation_string | Discipline of Biochemistry, "Victor Babes" University of Medicine and Pharmacy, 300041 Timis , oara, Romania; |
| authorships[4].institutions[0].id | https://openalex.org/I4210088791 |
| authorships[4].institutions[0].ror | https://ror.org/00afdp487 |
| authorships[4].institutions[0].type | education |
| authorships[4].institutions[0].lineage | https://openalex.org/I4210088791 |
| authorships[4].institutions[0].country_code | RO |
| authorships[4].institutions[0].display_name | Victor Babeș University of Medicine and Pharmacy Timișoara |
| authorships[4].author_position | last |
| authorships[4].raw_author_name | Catalin Marian |
| authorships[4].is_corresponding | False |
| authorships[4].raw_affiliation_strings | Center for Complex Network Science, “Victor Babes” University of Medicine and Pharmacy, 300041 Timişoara, Romania, Discipline of Biochemistry, "Victor Babes" University of Medicine and Pharmacy, 300041 Timis , oara, Romania; |
| has_content.pdf | True |
| has_content.grobid_xml | True |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://www.mdpi.com/1648-9144/60/4/571/pdf?version=1711788856 |
| open_access.oa_status | gold |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | Analysis of the Level of Adiponectin and Selected Cytokines in Patients with Knee Osteoarthritis |
| has_fulltext | True |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T10105 |
| primary_topic.field.id | https://openalex.org/fields/27 |
| primary_topic.field.display_name | Medicine |
| primary_topic.score | 0.9993000030517578 |
| primary_topic.domain.id | https://openalex.org/domains/4 |
| primary_topic.domain.display_name | Health Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/2745 |
| primary_topic.subfield.display_name | Rheumatology |
| primary_topic.display_name | Osteoarthritis Treatment and Mechanisms |
| related_works | https://openalex.org/W2748952813, https://openalex.org/W3031052312, https://openalex.org/W4389568370, https://openalex.org/W3032375762, https://openalex.org/W1995515455, https://openalex.org/W2080531066, https://openalex.org/W3108674512, https://openalex.org/W1506200166, https://openalex.org/W1489783725, https://openalex.org/W2148612803 |
| cited_by_count | 6 |
| counts_by_year[0].year | 2025 |
| counts_by_year[0].cited_by_count | 4 |
| counts_by_year[1].year | 2024 |
| counts_by_year[1].cited_by_count | 2 |
| locations_count | 4 |
| best_oa_location.id | doi:10.3390/medicina60040571 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S1008817457 |
| best_oa_location.source.issn | 1010-660X, 1648-9144 |
| best_oa_location.source.type | journal |
| best_oa_location.source.is_oa | True |
| best_oa_location.source.issn_l | 1010-660X |
| best_oa_location.source.is_core | True |
| best_oa_location.source.is_in_doaj | True |
| best_oa_location.source.display_name | Medicina |
| best_oa_location.source.host_organization | https://openalex.org/P4310310987 |
| best_oa_location.source.host_organization_name | Multidisciplinary Digital Publishing Institute |
| best_oa_location.source.host_organization_lineage | https://openalex.org/P4310310987 |
| best_oa_location.source.host_organization_lineage_names | Multidisciplinary Digital Publishing Institute |
| best_oa_location.license | cc-by |
| best_oa_location.pdf_url | https://www.mdpi.com/1648-9144/60/4/571/pdf?version=1711788856 |
| best_oa_location.version | publishedVersion |
| best_oa_location.raw_type | journal-article |
| best_oa_location.license_id | https://openalex.org/licenses/cc-by |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | True |
| best_oa_location.raw_source_name | Medicina |
| best_oa_location.landing_page_url | https://doi.org/10.3390/medicina60040571 |
| primary_location.id | doi:10.3390/medicina60040571 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S1008817457 |
| primary_location.source.issn | 1010-660X, 1648-9144 |
| primary_location.source.type | journal |
| primary_location.source.is_oa | True |
| primary_location.source.issn_l | 1010-660X |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | True |
| primary_location.source.display_name | Medicina |
| primary_location.source.host_organization | https://openalex.org/P4310310987 |
| primary_location.source.host_organization_name | Multidisciplinary Digital Publishing Institute |
| primary_location.source.host_organization_lineage | https://openalex.org/P4310310987 |
| primary_location.source.host_organization_lineage_names | Multidisciplinary Digital Publishing Institute |
| primary_location.license | cc-by |
| primary_location.pdf_url | https://www.mdpi.com/1648-9144/60/4/571/pdf?version=1711788856 |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | https://openalex.org/licenses/cc-by |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | Medicina |
| primary_location.landing_page_url | https://doi.org/10.3390/medicina60040571 |
| publication_date | 2024-03-30 |
| publication_year | 2024 |
| referenced_works | https://openalex.org/W1975890825, https://openalex.org/W4362471819, https://openalex.org/W4362673156, https://openalex.org/W2747777164, https://openalex.org/W1711018735, https://openalex.org/W2048826456, https://openalex.org/W2090189310, https://openalex.org/W4311357410, https://openalex.org/W2767601386, https://openalex.org/W2898869407, https://openalex.org/W2076014016, https://openalex.org/W2021234773, https://openalex.org/W2156074432, https://openalex.org/W2614249886, https://openalex.org/W3124450390, https://openalex.org/W2811010140, https://openalex.org/W6629330349, https://openalex.org/W3134091181, https://openalex.org/W6603069952, https://openalex.org/W2052204542, https://openalex.org/W3107012386, https://openalex.org/W1493004540, https://openalex.org/W2215739393, https://openalex.org/W1967057044, https://openalex.org/W3121609147, https://openalex.org/W4387707093, https://openalex.org/W4211096690, https://openalex.org/W2795130198, https://openalex.org/W1831943110, https://openalex.org/W2070835870, https://openalex.org/W2133895652, https://openalex.org/W1994363964, https://openalex.org/W2887489157, https://openalex.org/W3027806809, https://openalex.org/W4392349613, https://openalex.org/W4295123343, https://openalex.org/W2344716431, https://openalex.org/W2005158748, https://openalex.org/W2102019349, https://openalex.org/W4389338801, https://openalex.org/W74970606, https://openalex.org/W3010475122, https://openalex.org/W4392660914, https://openalex.org/W2415235746, https://openalex.org/W4376138550, https://openalex.org/W4391883429, https://openalex.org/W1982799140, https://openalex.org/W2062923543, https://openalex.org/W1900314297, https://openalex.org/W4300847486, https://openalex.org/W2077153720, https://openalex.org/W2125194714, https://openalex.org/W3029595496, https://openalex.org/W2004909190 |
| referenced_works_count | 54 |
| abstract_inverted_index.= | 197, 200, 220, 223, 248, 251, 257, 260, 283, 286, 292, 295 |
| abstract_inverted_index.A | 312 |
| abstract_inverted_index.a | 7, 52, 150, 188 |
| abstract_inverted_index.r | 199, 222, 250, 259, 285, 294 |
| abstract_inverted_index.(p | 196, 219, 247, 256, 282, 291 |
| abstract_inverted_index.24 | 100 |
| abstract_inverted_index.50 | 106 |
| abstract_inverted_index.In | 225, 262 |
| abstract_inverted_index.an | 57 |
| abstract_inverted_index.at | 31, 153 |
| abstract_inverted_index.be | 361 |
| abstract_inverted_index.by | 230 |
| abstract_inverted_index.in | 78, 111, 208, 236, 306, 356 |
| abstract_inverted_index.is | 6, 11, 216, 242, 342 |
| abstract_inverted_index.it | 232, 336 |
| abstract_inverted_index.of | 15, 25, 44, 108, 126, 134, 213, 239, 265, 269, 309 |
| abstract_inverted_index.to | 28, 68, 175, 245, 254, 273, 329, 345, 354, 360, 364 |
| abstract_inverted_index.All | 147 |
| abstract_inverted_index.KOA | 86, 103, 129 |
| abstract_inverted_index.The | 64, 164, 184 |
| abstract_inverted_index.age | 109, 192, 246, 316, 326, 341 |
| abstract_inverted_index.and | 1, 56, 61, 76, 82, 92, 94, 98, 104, 131, 138, 157, 167, 181, 193, 299, 317, 319, 321, 347, 349, 366 |
| abstract_inverted_index.are | 206, 351 |
| abstract_inverted_index.but | 18 |
| abstract_inverted_index.can | 40 |
| abstract_inverted_index.may | 327 |
| abstract_inverted_index.men | 290, 333 |
| abstract_inverted_index.the | 20, 23, 32, 42, 45, 112, 123, 127, 132, 154, 203, 211, 214, 228, 237, 263, 267, 270, 277, 307 |
| abstract_inverted_index.was | 117, 173, 233, 337 |
| abstract_inverted_index.BMI, | 300 |
| abstract_inverted_index.BMI; | 355 |
| abstract_inverted_index.IL-6 | 139, 348 |
| abstract_inverted_index.Knee | 3 |
| abstract_inverted_index.age, | 37 |
| abstract_inverted_index.case | 238, 264, 308 |
| abstract_inverted_index.data | 229 |
| abstract_inverted_index.from | 36, 122 |
| abstract_inverted_index.knee | 79, 156 |
| abstract_inverted_index.men. | 310 |
| abstract_inverted_index.more | 217, 243, 275, 343, 362 |
| abstract_inverted_index.only | 305 |
| abstract_inverted_index.over | 105 |
| abstract_inverted_index.pain | 95, 215, 365 |
| abstract_inverted_index.seem | 359 |
| abstract_inverted_index.that | 10, 235, 324, 339 |
| abstract_inverted_index.them | 84 |
| abstract_inverted_index.used | 174 |
| abstract_inverted_index.weak | 53 |
| abstract_inverted_index.were | 140, 158, 303 |
| abstract_inverted_index.with | 47, 51, 85, 102, 289, 334 |
| abstract_inverted_index.work | 66 |
| abstract_inverted_index.(KOA) | 5 |
| abstract_inverted_index.Also, | 202 |
| abstract_inverted_index.Apart | 35 |
| abstract_inverted_index.IL-10 | 204, 350 |
| abstract_inverted_index.IL-6, | 77, 322 |
| abstract_inverted_index.Index | 171 |
| abstract_inverted_index.WOMAC | 278 |
| abstract_inverted_index.X-ray | 152 |
| abstract_inverted_index.ages, | 17 |
| abstract_inverted_index.aimed | 67 |
| abstract_inverted_index.being | 49 |
| abstract_inverted_index.cases | 209 |
| abstract_inverted_index.data, | 89 |
| abstract_inverted_index.fluid | 116 |
| abstract_inverted_index.knees | 125 |
| abstract_inverted_index.level | 195 |
| abstract_inverted_index.lower | 207 |
| abstract_inverted_index.pain, | 180 |
| abstract_inverted_index.stage | 55 |
| abstract_inverted_index.tends | 27, 272 |
| abstract_inverted_index.total | 280 |
| abstract_inverted_index.using | 119, 142, 160 |
| abstract_inverted_index.where | 210 |
| abstract_inverted_index.which | 26 |
| abstract_inverted_index.women | 255, 358 |
| abstract_inverted_index.years | 107 |
| abstract_inverted_index.7013). | 296 |
| abstract_inverted_index.IL-10, | 74, 136 |
| abstract_inverted_index.assays | 145 |
| abstract_inverted_index.assess | 176 |
| abstract_inverted_index.excess | 38 |
| abstract_inverted_index.fluid, | 81 |
| abstract_inverted_index.global | 33 |
| abstract_inverted_index.level. | 34 |
| abstract_inverted_index.levels | 133 |
| abstract_inverted_index.males, | 240 |
| abstract_inverted_index.namely | 72 |
| abstract_inverted_index.number | 24 |
| abstract_inverted_index.people | 14 |
| abstract_inverted_index.study. | 114 |
| abstract_inverted_index.supine | 151 |
| abstract_inverted_index.target | 124, 155 |
| abstract_inverted_index.values | 205, 281 |
| abstract_inverted_index.weight | 39 |
| abstract_inverted_index.women, | 266, 335 |
| abstract_inverted_index.(K–L) | 162 |
| abstract_inverted_index.(WOMAC) | 172 |
| abstract_inverted_index.0.0079, | 249 |
| abstract_inverted_index.0.0203, | 258 |
| abstract_inverted_index.0.0289, | 293 |
| abstract_inverted_index.0.0405, | 221 |
| abstract_inverted_index.0.0451, | 198 |
| abstract_inverted_index.Ontario | 166 |
| abstract_inverted_index.TNF-α, | 75, 137 |
| abstract_inverted_index.Western | 165 |
| abstract_inverted_index.analyze | 69 |
| abstract_inverted_index.between | 59, 191, 315 |
| abstract_inverted_index.disease | 9, 271 |
| abstract_inverted_index.elderly | 21 |
| abstract_inverted_index.gender, | 231 |
| abstract_inverted_index.men’s | 340 |
| abstract_inverted_index.obesity | 48 |
| abstract_inverted_index.present | 65, 113 |
| abstract_inverted_index.related | 244, 344 |
| abstract_inverted_index.results | 186 |
| abstract_inverted_index.scores. | 96 |
| abstract_inverted_index.(ELISA). | 146 |
| abstract_inverted_index.0.00031, | 284 |
| abstract_inverted_index.0.6223). | 261 |
| abstract_inverted_index.0.7993), | 252 |
| abstract_inverted_index.0.8342), | 287 |
| abstract_inverted_index.ACRP-30, | 73, 135 |
| abstract_inverted_index.McMaster | 168 |
| abstract_inverted_index.Methods: | 99 |
| abstract_inverted_index.Results: | 183 |
| abstract_inverted_index.Synovial | 115 |
| abstract_inverted_index.advanced | 325 |
| abstract_inverted_index.changes, | 91 |
| abstract_inverted_index.clinical | 88 |
| abstract_inverted_index.compared | 253, 288 |
| abstract_inverted_index.directly | 352 |
| abstract_inverted_index.disease, | 46 |
| abstract_inverted_index.enrolled | 128 |
| abstract_inverted_index.grading. | 163 |
| abstract_inverted_index.guidance | 121 |
| abstract_inverted_index.increase | 29, 274 |
| abstract_inverted_index.measured | 141 |
| abstract_inverted_index.observed | 234, 304, 338 |
| abstract_inverted_index.obtained | 185 |
| abstract_inverted_index.patients | 148 |
| abstract_inverted_index.physical | 178 |
| abstract_inverted_index.specific | 70 |
| abstract_inverted_index.subjects | 101 |
| abstract_inverted_index.suggests | 323 |
| abstract_inverted_index.synovial | 80 |
| abstract_inverted_index.Comparing | 332 |
| abstract_inverted_index.Materials | 97 |
| abstract_inverted_index.Regarding | 297 |
| abstract_inverted_index.addition, | 226, 357 |
| abstract_inverted_index.analyzing | 227 |
| abstract_inverted_index.correlate | 83 |
| abstract_inverted_index.different | 16 |
| abstract_inverted_index.evolution | 43 |
| abstract_inverted_index.function, | 179 |
| abstract_inverted_index.harvested | 118 |
| abstract_inverted_index.imbalance | 58 |
| abstract_inverted_index.influence | 41 |
| abstract_inverted_index.intensity | 212 |
| abstract_inverted_index.patients, | 130 |
| abstract_inverted_index.rigidity, | 346 |
| abstract_inverted_index.score’s | 279 |
| abstract_inverted_index.sensitive | 363 |
| abstract_inverted_index.stiffness | 241 |
| abstract_inverted_index.targeting | 13 |
| abstract_inverted_index.underwent | 149 |
| abstract_inverted_index.Background | 0 |
| abstract_inverted_index.University | 169 |
| abstract_inverted_index.associated | 50 |
| abstract_inverted_index.classified | 159 |
| abstract_inverted_index.contribute | 328 |
| abstract_inverted_index.correlated | 353 |
| abstract_inverted_index.cytokines. | 63 |
| abstract_inverted_index.especially | 19 |
| abstract_inverted_index.functional | 93 |
| abstract_inverted_index.pronounced | 218 |
| abstract_inverted_index.reduction. | 331 |
| abstract_inverted_index.stiffness. | 182, 367 |
| abstract_inverted_index.ultrasound | 120 |
| abstract_inverted_index.−0.412). | 201 |
| abstract_inverted_index.−0.421). | 224 |
| abstract_inverted_index.Objectives: | 2 |
| abstract_inverted_index.adiponectin | 194, 320, 330 |
| abstract_inverted_index.biomarkers, | 71 |
| abstract_inverted_index.correlation | 190, 314 |
| abstract_inverted_index.highlighted | 187 |
| abstract_inverted_index.intensively | 276 |
| abstract_inverted_index.participate | 110 |
| abstract_inverted_index.patients’ | 87 |
| abstract_inverted_index.population, | 22 |
| abstract_inverted_index.progression | 268 |
| abstract_inverted_index.significant | 189, 301, 313 |
| abstract_inverted_index.Conclusions: | 311 |
| abstract_inverted_index.adiponectin, | 318 |
| abstract_inverted_index.continuously | 12, 30 |
| abstract_inverted_index.correlations | 302 |
| abstract_inverted_index.degenerative | 8 |
| abstract_inverted_index.inflammation | 54 |
| abstract_inverted_index.interleukins | 298 |
| abstract_inverted_index.radiographic | 90 |
| abstract_inverted_index.enzyme-linked | 143 |
| abstract_inverted_index.immunosorbent | 144 |
| abstract_inverted_index.self-reported | 177 |
| abstract_inverted_index.Osteoarthritis | 170 |
| abstract_inverted_index.osteoarthritis | 4 |
| abstract_inverted_index.pro-inflammatory | 60 |
| abstract_inverted_index.anti-inflammatory | 62 |
| abstract_inverted_index.Kellgren–Lawrence | 161 |
| cited_by_percentile_year.max | 98 |
| cited_by_percentile_year.min | 94 |
| countries_distinct_count | 1 |
| institutions_distinct_count | 5 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/3 |
| sustainable_development_goals[0].score | 0.7799999713897705 |
| sustainable_development_goals[0].display_name | Good health and well-being |
| citation_normalized_percentile.value | 0.92808107 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | True |