Anemia before reimplantation surgery Article Swipe
Faustine Bredèche
,
Isabelle Gounot
,
Vincent Belgaïd
,
Caroline Macabéo
,
Kaissar Rouhana
,
Frédéric Aubrun
,
Tristan Ferry
,
Elvire Servıen
,
Sébastien Lustıg
,
Mikhail Dziadzko
·
YOU?
·
· 2020
· Open Access
·
· DOI: https://doi.org/10.1051/sicotj/2020046
YOU?
·
· 2020
· Open Access
·
· DOI: https://doi.org/10.1051/sicotj/2020046
Introduction : Preoperative anemia in patients undergoing a two-stage septic revision arthroplasty may be a factor of reinfection, even in the presence of aggressive antimicrobial therapy. Patient Blood Management (PBM) in such patients is challenging. We evaluate the impact of anemia existing before re-implantation on a failure rate after two-stage septic total knee arthroplasty (rTKA), and explore feasibility of a PBM strategy implementation in these patients. Materials and methods : A retrospective study of patients from January 2010 to January 2015 in a French regional referral center was performed. Patients undergoing a two-stage rTKA for infection after successful primary TKA were identified and followed up to 31.12.2018. The primary outcome (failure) was defined as surgical site infection after re-implantation requiring new surgery. The secondary outcomes were time to failure, the time between explantation/reimplantation, transfusion rate during the second stage. Preoperative anemia was defined as Hb level < 12 g/L before the re-implantation. Results : 69 patients were identified; 17 (24%) developed reinfection of rTKA in 105 [11.4–156] days. In these patients pre-implantation anemia was more frequent ( n = 13(76.5%) in failed vs. n = 21(40%) in non-failed, p = 0.0110). During the explantation stage, there were no significant group differences in age, sex, comorbidity, type of spacer and antimicrobial therapy, iron supplementation, or transfusion rate. The median time between explantation/reimplantation surgery was 51 [43–71.5] days, indifferent between the two groups. Intraoperative transfusion during reimplantation was required in 12 (17%) patients, more frequent in failed patients. None of the patients had contraindications for the PBM strategy except the cell-saver use. Conclusion : In two-stage septic rTKA preoperative anemia was almost two times more frequent and associated with an elevated rate of septic failure. The time-frame between explantation and-re-implantation is sufficient to implement a PBM strategy for all anemic patients. Before-after studies would be of interest to determine the best PBM strategy to prevent anemia-associated septic failure in such a condition.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1051/sicotj/2020046
- https://www.sicot-j.org/articles/sicotj/pdf/2020/01/sicotj200134.pdf
- OA Status
- gold
- Cited By
- 6
- References
- 20
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W3111575624
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W3111575624Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1051/sicotj/2020046Digital Object Identifier
- Title
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Anemia before reimplantation surgeryWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
-
2020Year of publication
- Publication date
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2020-01-01Full publication date if available
- Authors
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Faustine Bredèche, Isabelle Gounot, Vincent Belgaïd, Caroline Macabéo, Kaissar Rouhana, Frédéric Aubrun, Tristan Ferry, Elvire Servıen, Sébastien Lustıg, Mikhail DziadzkoList of authors in order
- Landing page
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https://doi.org/10.1051/sicotj/2020046Publisher landing page
- PDF URL
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https://www.sicot-j.org/articles/sicotj/pdf/2020/01/sicotj200134.pdfDirect link to full text PDF
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YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
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https://www.sicot-j.org/articles/sicotj/pdf/2020/01/sicotj200134.pdfDirect OA link when available
- Concepts
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Medicine, Surgery, Anemia, Blood transfusion, Comorbidity, Stage (stratigraphy), Retrospective cohort study, Internal medicine, Paleontology, BiologyTop concepts (fields/topics) attached by OpenAlex
- Cited by
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6Total citation count in OpenAlex
- Citations by year (recent)
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2025: 2, 2024: 1, 2023: 1, 2022: 1, 2021: 1Per-year citation counts (last 5 years)
- References (count)
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20Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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