Antibacterial and Anti‐Inflammatory Activity of Chitosan Film with Rhodomyrtus Tomentosa Leaf Extract Prepared Via 3D‐Printing Method Article Swipe
Vo An Quan
,
Nguyễn Thúy Chinh
,
Uyen Thu Pham
,
Tuan Anh Nguyen
,
Duong Thanh Nguyen
,
Tran Dung Hoang
,
Lu Trong Le
,
Thi Cam Quyen Ngo
,
Thái Hoàng
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1002/open.202400302
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1002/open.202400302
The combination of natural polymers and plant extract attracted much attention thanks to its valuable biological activities. This study presents the preparation and characterization of chitosan (CS) film containing Rhodomyrtus tomentosa leaf extract. In which, the Rhodomyrtus tomentosa leaf extract (SLE) with polyphenol‐rich fractions was extracted by an ultrasonic‐assisted extraction method. The prepared chitosan/polyphenol‐rich fractions film (CSPPF) was characterized using infrared (IR) spectroscopy, mechanical testing, scanning electron microscopy (SEM), and water absorption analysis. Antibacterial and anti‐inflammatory activities of the CSPPF were assessed using the agar well diffusion method and nitric oxide (NO) inhibition assays, respectively. Besides, the release of the extract from the CSPPF as well as the drug release kinetics was also tested. The Rhodomyrtus tomentosa leaf extract enhanced the antibacterial efficacy against Escherichia coli and enhanced the anti‐inflammatory activity as well as the swelling ability of the CSPPF. The CSPPF containing 1 wt.% of SLE can inhibit 77.70 % NO with an IC 50 value of 19.40 μg/mL.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1002/open.202400302
- OA Status
- gold
- Cited By
- 1
- References
- 59
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4404652514
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4404652514Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1002/open.202400302Digital Object Identifier
- Title
-
Antibacterial and Anti‐Inflammatory Activity of Chitosan Film with Rhodomyrtus Tomentosa Leaf Extract Prepared Via 3D‐Printing MethodWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2024Year of publication
- Publication date
-
2024-11-22Full publication date if available
- Authors
-
Vo An Quan, Nguyễn Thúy Chinh, Uyen Thu Pham, Tuan Anh Nguyen, Duong Thanh Nguyen, Tran Dung Hoang, Lu Trong Le, Thi Cam Quyen Ngo, Thái HoàngList of authors in order
- Landing page
-
https://doi.org/10.1002/open.202400302Publisher landing page
- Open access
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YesWhether a free full text is available
- OA status
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goldOpen access status per OpenAlex
- OA URL
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https://doi.org/10.1002/open.202400302Direct OA link when available
- Concepts
-
Chitosan, Antibacterial activity, Chemistry, Nuclear chemistry, Polyphenol, Agar diffusion test, Extraction (chemistry), Anti-inflammatory, Chromatography, Agar, Escherichia coli, Organic chemistry, Biochemistry, Antioxidant, Bacteria, Biology, Genetics, Pharmacology, GeneTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
1Total citation count in OpenAlex
- Citations by year (recent)
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2025: 1Per-year citation counts (last 5 years)
- References (count)
-
59Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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