Antimicrobial therapy and outcome of methicillin-resistant Staphylococcus aureus endocarditis: A retrospective multicenter study in Japan Article Swipe

PDF

Related Concepts

Medicine Infective endocarditis Antimicrobial Staphylococcus aureus Endocarditis Methicillin-resistant Staphylococcus aureus Retrospective cohort study Medical microbiology Staphylococcal infections Internal medicine Microbiology Immunology Bacteria Biology Genetics

Kotaro Mitsutake , N. Shinya , Masafumi Seki , Takahiro Ohara , Kohei Uemura , Masato Fukunaga , Jun Sakai , Miki Nagao , Makoto Sata , Yohei Hamada , Hitoshi Kawasuji , Yoshihiro Yamamoto , Masashi Nakamatsu , Yusuke Koizumi , Hiroshige Mikamo , Akira Ukimura , Tetsuji Aoyagi , Toyomitsu Sawai , Takeshi Tanaka , Koichi Izumikawa , Yoko Takayama , Kiwamu Nakamura , Keiji Kanemitsu , Issei Tokimatsu , Kazuhiko Nakajima , Dai Akine ·

YOU? · · 2024 · Open Access · · DOI: https://doi.org/10.1016/j.jiac.2024.02.027 · OA: W4392388378

Glycopeptide and daptomycin were the preferred antibiotics for the initial therapy of MRSA-IE. Antimicrobial regimens were changed for various reasons. Prognosis was not significantly affected by choice of antibiotic therapy (glycopeptide, daptomycin, linezolid), but further studies are needed to determine which antimicrobials are optimal as first-line agents.