Antiseptic Activity of Alchornea cordifolia (Schumach & Thonn.) Mull.-Arg. (Euphorbiaceae) Aqueous Leaves Extract on Oral and Dental Bacteria Article Swipe
Ngene Jean Pierre
,
Yinyang Jacques
,
Kidik Pouka Marie Cathérine
,
Eyetemou Miguel
,
Etame Loe Gisèle Marie Marguérite
·
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.36348/sjodr.2022.v07i07.001
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.36348/sjodr.2022.v07i07.001
Some infectious oral diseases are treated by medicinal plants in tropical areas, because they are abundant and cheap. The present work aimed to evaluate the antiseptic activity of the aqueous extract of Alchornea cordifolia leaves against three oral bacteria recognised as opportunistic pathogens, namely Streptococcus mitis, Staphylococcus epidermidis, and Micrococcus luteus. Fresh leaves of A. cordifolia were harvested, dried and pulverised. The extraction was performed by decocting in distilled water. The phytochemical screening was performed on the extract based on principles of colour change, and precipitation. Biological studies consisted in the in vitro antiseptic evaluation of the aqueous extract using the agar disc diffusion method, in comparison with a reference antiseptic mouthwash containing chlorhexidine. The extract had a 11.96% yield. The phytochemical screening revealed the presence of alkaloids, phenols, flavonoids, terpenes, tannins, glycosides, coumarins and saponins. The evaluation of the antiseptic activity revealed that the extract is active against S. mitis and S. epidermidis, and inactive against M. luteus. The diameters of inhibition zones were 16.9±1.1mm and 11.2±0.7mm at the concentration of 40mg/ml, and 7.7±0.3mm and 8.5±0.5mm at the concentration of 20mg/ml against S. mitis and S. epidermidis, respectively. Chlorhexidine did not inhibit S. mitis and showed diameters of inhibition of 13.0±1.0mm and 15.1±1.0mm against S. epidermidis and M. luteus, respectively. The minimal inhibitory concentration of the extract against the 2 sensitive bacteria was 20mg/ml.
Related Topics
Concepts
Phytochemical
Antiseptic
Micrococcus luteus
Traditional medicine
Streptococcus mitis
Chemistry
Staphylococcus epidermidis
Chlorhexidine
Food science
Bacteria
Biology
Staphylococcus aureus
Medicine
Streptococcus
Organic chemistry
Dentistry
Genetics
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.36348/sjodr.2022.v07i07.001
- https://doi.org/10.36348/sjodr.2022.v07i07.001
- OA Status
- diamond
- Cited By
- 1
- References
- 3
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4285598795
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4285598795Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.36348/sjodr.2022.v07i07.001Digital Object Identifier
- Title
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Antiseptic Activity of Alchornea cordifolia (Schumach & Thonn.) Mull.-Arg. (Euphorbiaceae) Aqueous Leaves Extract on Oral and Dental BacteriaWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2022Year of publication
- Publication date
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2022-07-08Full publication date if available
- Authors
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Ngene Jean Pierre, Yinyang Jacques, Kidik Pouka Marie Cathérine, Eyetemou Miguel, Etame Loe Gisèle Marie MarguériteList of authors in order
- Landing page
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https://doi.org/10.36348/sjodr.2022.v07i07.001Publisher landing page
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https://doi.org/10.36348/sjodr.2022.v07i07.001Direct link to full text PDF
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YesWhether a free full text is available
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diamondOpen access status per OpenAlex
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https://doi.org/10.36348/sjodr.2022.v07i07.001Direct OA link when available
- Concepts
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Phytochemical, Antiseptic, Micrococcus luteus, Traditional medicine, Streptococcus mitis, Chemistry, Staphylococcus epidermidis, Chlorhexidine, Food science, Bacteria, Biology, Staphylococcus aureus, Medicine, Streptococcus, Organic chemistry, Dentistry, GeneticsTop concepts (fields/topics) attached by OpenAlex
- Cited by
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1Total citation count in OpenAlex
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2025: 1Per-year citation counts (last 5 years)
- References (count)
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3Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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