Apathy in Patients With Cerebral Amyloid Angiopathy Article Swipe

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Anthipa Chokesuwattanaskul , Maria Clara Zanon Zotin , Dorothée Schoemaker , Lukas Sveikata , M. Edip Gurol , Steven M. Greenberg , Anand Viswanathan ·

YOU? · · 2023 · Open Access · · DOI: https://doi.org/10.1212/wnl.0000000000207200

Our findings revealed the orbitofrontal cortex as a key region in the reward circuit associated with apathy in sporadic cerebral amyloid angiopathy, independent from depression. Apathy was shown to be associated with a higher CAA-SVD score and an extensive disruption of white matter tracts, which suggested that a higher burden of CAA pathology and the disruption in large-scale white matter networks may underlie manifestations of apathy.

Related Topics

Cerebral Amyloid Angiopathy

Concepts

Apathy Cerebral amyloid angiopathy Neuroimaging Dementia Medicine Neuropsychology Voxel-based morphometry Psychology Depression (economics) Voxel Internal medicine White matter Psychiatry Magnetic resonance imaging Disease Radiology Cognition Economics Macroeconomics

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Type: article
Language: en
Landing Page: https://doi.org/10.1212/wnl.0000000000207200
PDF: https://n.neurology.org/content/neurology/100/19/e2007.full.pdf
OA Status: bronze
Cited By: 15
References: 51
Related Works: 10
OpenAlex ID: https://openalex.org/W4327914007

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OpenAlex ID: https://openalex.org/W4327914007

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DOI: https://doi.org/10.1212/wnl.0000000000207200

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Title: Apathy in Patients With Cerebral Amyloid Angiopathy

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Type: article

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Language: en

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Publication year: 2023

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Publication date: 2023-03-20

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Authors: Anthipa Chokesuwattanaskul, Maria Clara Zanon Zotin, Dorothée Schoemaker, Lukas Sveikata, M. Edip Gurol, Steven M. Greenberg, Anand Viswanathan

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Landing page: https://doi.org/10.1212/wnl.0000000000207200

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PDF URL: https://n.neurology.org/content/neurology/100/19/e2007.full.pdf

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OA status: bronze

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Concepts: Apathy, Cerebral amyloid angiopathy, Neuroimaging, Dementia, Medicine, Neuropsychology, Voxel-based morphometry, Psychology, Depression (economics), Voxel, Internal medicine, White matter, Psychiatry, Magnetic resonance imaging, Disease, Radiology, Cognition, Economics, Macroeconomics

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Cited by: 15

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Citations by year (recent): 2025: 7, 2024: 8

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References (count): 51

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Related works (count): 10

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