Application of a BIlinear Rotation Decoupling (BIRD) filter in combination with J‐difference editing for indirect 13C measurements in the human liver Article Swipe
Pandichelvam Veeraiah
,
Kim Brouwers
,
Joachim E. Wildberger
,
Vera B. Schrauwen‐Hinderling
,
Lucas Lindeboom
·
YOU?
·
· 2020
· Open Access
·
· DOI: https://doi.org/10.1002/mrm.28394
YOU?
·
· 2020
· Open Access
·
· DOI: https://doi.org/10.1002/mrm.28394
Purpose Recently, we introduced a quantum coherence based method (ge‐HSQC) for indirect 13 C‐MRS in the liver to track 13 C‐labeled lipids into the hepatic lipid pool in vivo. This approach is more robust in case of respiratory motion, however, inherently leads to a signal loss of 50% when compared with a conventional J‐difference editing technique (JDE). Here, we intend to improve the robustness of a regular JDE (STEAM‐ACED) with the use of a BIlinear Rotation Decoupling (BIRD) filter to achieve 100% higher signal gain when compared with ge‐HSQC. Methods To determine the efficiency of the BIRD filter 1 H‐[ 13 C] lipid spectra were acquired on 3T from a peanut oil phantom, with three different MR sequences: ge‐HSQC, STEAM‐ACED, and the BIRD filter together with STEAM‐ACED (BIRD‐STEAM‐ACED). Finally, our proposed method is tested in vivo in five healthy volunteers with varying liver fat content. In these subjects we quantified the 1 H‐[ 13 C]‐signal from the hepatic lipid pool and determined 13 C enrichment, which is expected to be 1.1% according to the natural abundance of 13 C. Results The application of the proposed BIRD filter reduces the subtraction artifact of 1 H‐[ 12 C] lipid signal efficiently in JDE experiments, which leads to a signal gain of 100% of 1 H‐[ 13 C]‐lipid signals when compared with the ge‐HSQC. Phase distortions in vivo were minimal with the use of BIRD compared with STEAM‐ACED, which enabled us to robustly quantify the 13 C‐enrichment in all five subjects. Conclusion The BIRD‐STEAM‐ACED sequence is an efficient and promising tool for 13 C‐tracking experiments in the human liver in vivo.
Related Topics
Concepts
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1002/mrm.28394
- https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mrm.28394
- OA Status
- hybrid
- Cited By
- 6
- References
- 13
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W3039490549
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W3039490549Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1002/mrm.28394Digital Object Identifier
- Title
-
Application of a BIlinear Rotation Decoupling (BIRD) filter in combination with J‐difference editing for indirect 13C measurements in the human liverWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2020Year of publication
- Publication date
-
2020-07-03Full publication date if available
- Authors
-
Pandichelvam Veeraiah, Kim Brouwers, Joachim E. Wildberger, Vera B. Schrauwen‐Hinderling, Lucas LindeboomList of authors in order
- Landing page
-
https://doi.org/10.1002/mrm.28394Publisher landing page
- PDF URL
-
https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mrm.28394Direct link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
hybridOpen access status per OpenAlex
- OA URL
-
https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mrm.28394Direct OA link when available
- Concepts
-
Robustness (evolution), Heteronuclear single quantum coherence spectroscopy, In vivo, Biological system, Chemistry, Nuclear magnetic resonance, Mathematics, Physics, Biology, Biochemistry, Gene, Nuclear magnetic resonance spectroscopy, BiotechnologyTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
6Total citation count in OpenAlex
- Citations by year (recent)
-
2023: 1, 2022: 2, 2021: 2, 2020: 1Per-year citation counts (last 5 years)
- References (count)
-
13Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W3039490549 |
|---|---|
| doi | https://doi.org/10.1002/mrm.28394 |
| ids.doi | https://doi.org/10.1002/mrm.28394 |
| ids.mag | 3039490549 |
| ids.pmid | https://pubmed.ncbi.nlm.nih.gov/32618391 |
| ids.openalex | https://openalex.org/W3039490549 |
| fwci | 0.75429136 |
| mesh[0].qualifier_ui | |
| mesh[0].descriptor_ui | D064368 |
| mesh[0].is_major_topic | False |
| mesh[0].qualifier_name | |
| mesh[0].descriptor_name | Healthy Volunteers |
| mesh[1].qualifier_ui | |
| mesh[1].descriptor_ui | D006801 |
| mesh[1].is_major_topic | False |
| mesh[1].qualifier_name | |
| mesh[1].descriptor_name | Humans |
| mesh[2].qualifier_ui | |
| mesh[2].descriptor_ui | D008055 |
| mesh[2].is_major_topic | True |
| mesh[2].qualifier_name | |
| mesh[2].descriptor_name | Lipids |
| mesh[3].qualifier_ui | Q000000981 |
| mesh[3].descriptor_ui | D008099 |
| mesh[3].is_major_topic | True |
| mesh[3].qualifier_name | diagnostic imaging |
| mesh[3].descriptor_name | Liver |
| mesh[4].qualifier_ui | |
| mesh[4].descriptor_ui | D019047 |
| mesh[4].is_major_topic | False |
| mesh[4].qualifier_name | |
| mesh[4].descriptor_name | Phantoms, Imaging |
| mesh[5].qualifier_ui | |
| mesh[5].descriptor_ui | D012399 |
| mesh[5].is_major_topic | False |
| mesh[5].qualifier_name | |
| mesh[5].descriptor_name | Rotation |
| mesh[6].qualifier_ui | |
| mesh[6].descriptor_ui | D064368 |
| mesh[6].is_major_topic | False |
| mesh[6].qualifier_name | |
| mesh[6].descriptor_name | Healthy Volunteers |
| mesh[7].qualifier_ui | |
| mesh[7].descriptor_ui | D006801 |
| mesh[7].is_major_topic | False |
| mesh[7].qualifier_name | |
| mesh[7].descriptor_name | Humans |
| mesh[8].qualifier_ui | |
| mesh[8].descriptor_ui | D008055 |
| mesh[8].is_major_topic | True |
| mesh[8].qualifier_name | |
| mesh[8].descriptor_name | Lipids |
| mesh[9].qualifier_ui | Q000000981 |
| mesh[9].descriptor_ui | D008099 |
| mesh[9].is_major_topic | True |
| mesh[9].qualifier_name | diagnostic imaging |
| mesh[9].descriptor_name | Liver |
| mesh[10].qualifier_ui | |
| mesh[10].descriptor_ui | D019047 |
| mesh[10].is_major_topic | False |
| mesh[10].qualifier_name | |
| mesh[10].descriptor_name | Phantoms, Imaging |
| mesh[11].qualifier_ui | |
| mesh[11].descriptor_ui | D012399 |
| mesh[11].is_major_topic | False |
| mesh[11].qualifier_name | |
| mesh[11].descriptor_name | Rotation |
| type | article |
| title | Application of a BIlinear Rotation Decoupling (BIRD) filter in combination with J‐difference editing for indirect 13C measurements in the human liver |
| awards[0].id | https://openalex.org/G8708953729 |
| awards[0].funder_id | https://openalex.org/F4320321708 |
| awards[0].display_name | |
| awards[0].funder_award_id | a junior fellowship (2017.81.004) |
| awards[0].funder_display_name | Diabetes Fonds |
| biblio.issue | 6 |
| biblio.volume | 84 |
| biblio.last_page | 2917 |
| biblio.first_page | 2911 |
| topics[0].id | https://openalex.org/T10378 |
| topics[0].field.id | https://openalex.org/fields/27 |
| topics[0].field.display_name | Medicine |
| topics[0].score | 0.9998000264167786 |
| topics[0].domain.id | https://openalex.org/domains/4 |
| topics[0].domain.display_name | Health Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/2741 |
| topics[0].subfield.display_name | Radiology, Nuclear Medicine and Imaging |
| topics[0].display_name | Advanced MRI Techniques and Applications |
| topics[1].id | https://openalex.org/T11809 |
| topics[1].field.id | https://openalex.org/fields/16 |
| topics[1].field.display_name | Chemistry |
| topics[1].score | 0.9995999932289124 |
| topics[1].domain.id | https://openalex.org/domains/3 |
| topics[1].domain.display_name | Physical Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/1607 |
| topics[1].subfield.display_name | Spectroscopy |
| topics[1].display_name | Advanced NMR Techniques and Applications |
| topics[2].id | https://openalex.org/T10351 |
| topics[2].field.id | https://openalex.org/fields/27 |
| topics[2].field.display_name | Medicine |
| topics[2].score | 0.9980999827384949 |
| topics[2].domain.id | https://openalex.org/domains/4 |
| topics[2].domain.display_name | Health Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/2713 |
| topics[2].subfield.display_name | Epidemiology |
| topics[2].display_name | Liver Disease Diagnosis and Treatment |
| funders[0].id | https://openalex.org/F4320321708 |
| funders[0].ror | https://ror.org/04ch2g225 |
| funders[0].display_name | Diabetes Fonds |
| is_xpac | False |
| apc_list.value | 3500 |
| apc_list.currency | USD |
| apc_list.value_usd | 3500 |
| apc_paid.value | 3500 |
| apc_paid.currency | USD |
| apc_paid.value_usd | 3500 |
| concepts[0].id | https://openalex.org/C63479239 |
| concepts[0].level | 3 |
| concepts[0].score | 0.5418754816055298 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q7353546 |
| concepts[0].display_name | Robustness (evolution) |
| concepts[1].id | https://openalex.org/C193125475 |
| concepts[1].level | 3 |
| concepts[1].score | 0.4404401183128357 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q17029192 |
| concepts[1].display_name | Heteronuclear single quantum coherence spectroscopy |
| concepts[2].id | https://openalex.org/C207001950 |
| concepts[2].level | 2 |
| concepts[2].score | 0.4338805079460144 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q141124 |
| concepts[2].display_name | In vivo |
| concepts[3].id | https://openalex.org/C186060115 |
| concepts[3].level | 1 |
| concepts[3].score | 0.3979119062423706 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q30336093 |
| concepts[3].display_name | Biological system |
| concepts[4].id | https://openalex.org/C185592680 |
| concepts[4].level | 0 |
| concepts[4].score | 0.39648503065109253 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q2329 |
| concepts[4].display_name | Chemistry |
| concepts[5].id | https://openalex.org/C46141821 |
| concepts[5].level | 1 |
| concepts[5].score | 0.3834875226020813 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q209402 |
| concepts[5].display_name | Nuclear magnetic resonance |
| concepts[6].id | https://openalex.org/C33923547 |
| concepts[6].level | 0 |
| concepts[6].score | 0.3626294732093811 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q395 |
| concepts[6].display_name | Mathematics |
| concepts[7].id | https://openalex.org/C121332964 |
| concepts[7].level | 0 |
| concepts[7].score | 0.2425418496131897 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q413 |
| concepts[7].display_name | Physics |
| concepts[8].id | https://openalex.org/C86803240 |
| concepts[8].level | 0 |
| concepts[8].score | 0.23071184754371643 |
| concepts[8].wikidata | https://www.wikidata.org/wiki/Q420 |
| concepts[8].display_name | Biology |
| concepts[9].id | https://openalex.org/C55493867 |
| concepts[9].level | 1 |
| concepts[9].score | 0.15784737467765808 |
| concepts[9].wikidata | https://www.wikidata.org/wiki/Q7094 |
| concepts[9].display_name | Biochemistry |
| concepts[10].id | https://openalex.org/C104317684 |
| concepts[10].level | 2 |
| concepts[10].score | 0.11612078547477722 |
| concepts[10].wikidata | https://www.wikidata.org/wiki/Q7187 |
| concepts[10].display_name | Gene |
| concepts[11].id | https://openalex.org/C66974803 |
| concepts[11].level | 2 |
| concepts[11].score | 0.1104578971862793 |
| concepts[11].wikidata | https://www.wikidata.org/wiki/Q10359898 |
| concepts[11].display_name | Nuclear magnetic resonance spectroscopy |
| concepts[12].id | https://openalex.org/C150903083 |
| concepts[12].level | 1 |
| concepts[12].score | 0.08834433555603027 |
| concepts[12].wikidata | https://www.wikidata.org/wiki/Q7108 |
| concepts[12].display_name | Biotechnology |
| keywords[0].id | https://openalex.org/keywords/robustness |
| keywords[0].score | 0.5418754816055298 |
| keywords[0].display_name | Robustness (evolution) |
| keywords[1].id | https://openalex.org/keywords/heteronuclear-single-quantum-coherence-spectroscopy |
| keywords[1].score | 0.4404401183128357 |
| keywords[1].display_name | Heteronuclear single quantum coherence spectroscopy |
| keywords[2].id | https://openalex.org/keywords/in-vivo |
| keywords[2].score | 0.4338805079460144 |
| keywords[2].display_name | In vivo |
| keywords[3].id | https://openalex.org/keywords/biological-system |
| keywords[3].score | 0.3979119062423706 |
| keywords[3].display_name | Biological system |
| keywords[4].id | https://openalex.org/keywords/chemistry |
| keywords[4].score | 0.39648503065109253 |
| keywords[4].display_name | Chemistry |
| keywords[5].id | https://openalex.org/keywords/nuclear-magnetic-resonance |
| keywords[5].score | 0.3834875226020813 |
| keywords[5].display_name | Nuclear magnetic resonance |
| keywords[6].id | https://openalex.org/keywords/mathematics |
| keywords[6].score | 0.3626294732093811 |
| keywords[6].display_name | Mathematics |
| keywords[7].id | https://openalex.org/keywords/physics |
| keywords[7].score | 0.2425418496131897 |
| keywords[7].display_name | Physics |
| keywords[8].id | https://openalex.org/keywords/biology |
| keywords[8].score | 0.23071184754371643 |
| keywords[8].display_name | Biology |
| keywords[9].id | https://openalex.org/keywords/biochemistry |
| keywords[9].score | 0.15784737467765808 |
| keywords[9].display_name | Biochemistry |
| keywords[10].id | https://openalex.org/keywords/gene |
| keywords[10].score | 0.11612078547477722 |
| keywords[10].display_name | Gene |
| keywords[11].id | https://openalex.org/keywords/nuclear-magnetic-resonance-spectroscopy |
| keywords[11].score | 0.1104578971862793 |
| keywords[11].display_name | Nuclear magnetic resonance spectroscopy |
| keywords[12].id | https://openalex.org/keywords/biotechnology |
| keywords[12].score | 0.08834433555603027 |
| keywords[12].display_name | Biotechnology |
| language | en |
| locations[0].id | doi:10.1002/mrm.28394 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S111160002 |
| locations[0].source.issn | 0740-3194, 1522-2594 |
| locations[0].source.type | journal |
| locations[0].source.is_oa | False |
| locations[0].source.issn_l | 0740-3194 |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | False |
| locations[0].source.display_name | Magnetic Resonance in Medicine |
| locations[0].source.host_organization | https://openalex.org/P4310320595 |
| locations[0].source.host_organization_name | Wiley |
| locations[0].source.host_organization_lineage | https://openalex.org/P4310320595 |
| locations[0].source.host_organization_lineage_names | Wiley |
| locations[0].license | cc-by-nc-nd |
| locations[0].pdf_url | https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mrm.28394 |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | https://openalex.org/licenses/cc-by-nc-nd |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | Magnetic Resonance in Medicine |
| locations[0].landing_page_url | https://doi.org/10.1002/mrm.28394 |
| locations[1].id | pmid:32618391 |
| locations[1].is_oa | False |
| locations[1].source.id | https://openalex.org/S4306525036 |
| locations[1].source.issn | |
| locations[1].source.type | repository |
| locations[1].source.is_oa | False |
| locations[1].source.issn_l | |
| locations[1].source.is_core | False |
| locations[1].source.is_in_doaj | False |
| locations[1].source.display_name | PubMed |
| locations[1].source.host_organization | https://openalex.org/I1299303238 |
| locations[1].source.host_organization_name | National Institutes of Health |
| locations[1].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[1].license | |
| locations[1].pdf_url | |
| locations[1].version | publishedVersion |
| locations[1].raw_type | |
| locations[1].license_id | |
| locations[1].is_accepted | True |
| locations[1].is_published | True |
| locations[1].raw_source_name | Magnetic resonance in medicine |
| locations[1].landing_page_url | https://pubmed.ncbi.nlm.nih.gov/32618391 |
| locations[2].id | pmh:oai:pubmedcentral.nih.gov:7540382 |
| locations[2].is_oa | True |
| locations[2].source.id | https://openalex.org/S2764455111 |
| locations[2].source.issn | |
| locations[2].source.type | repository |
| locations[2].source.is_oa | False |
| locations[2].source.issn_l | |
| locations[2].source.is_core | False |
| locations[2].source.is_in_doaj | False |
| locations[2].source.display_name | PubMed Central |
| locations[2].source.host_organization | https://openalex.org/I1299303238 |
| locations[2].source.host_organization_name | National Institutes of Health |
| locations[2].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[2].license | other-oa |
| locations[2].pdf_url | |
| locations[2].version | submittedVersion |
| locations[2].raw_type | Text |
| locations[2].license_id | https://openalex.org/licenses/other-oa |
| locations[2].is_accepted | False |
| locations[2].is_published | False |
| locations[2].raw_source_name | Magn Reson Med |
| locations[2].landing_page_url | https://www.ncbi.nlm.nih.gov/pmc/articles/7540382 |
| locations[3].id | pmh:um:oai:cris.maastrichtuniversity.nl:publications/c2edc6f7-cbc7-4f74-a4b7-e70fecfacede |
| locations[3].is_oa | True |
| locations[3].source.id | https://openalex.org/S4306401843 |
| locations[3].source.issn | |
| locations[3].source.type | repository |
| locations[3].source.is_oa | False |
| locations[3].source.issn_l | |
| locations[3].source.is_core | False |
| locations[3].source.is_in_doaj | False |
| locations[3].source.display_name | Data Archiving and Networked Services (DANS) |
| locations[3].source.host_organization | https://openalex.org/I1322597698 |
| locations[3].source.host_organization_name | Royal Netherlands Academy of Arts and Sciences |
| locations[3].source.host_organization_lineage | https://openalex.org/I1322597698 |
| locations[3].license | cc-by-nc-nd |
| locations[3].pdf_url | |
| locations[3].version | submittedVersion |
| locations[3].raw_type | info:eu-repo/semantics/article |
| locations[3].license_id | https://openalex.org/licenses/cc-by-nc-nd |
| locations[3].is_accepted | False |
| locations[3].is_published | False |
| locations[3].raw_source_name | Magnetic Resonance in Medicine, 84(6), 2911 - 2917. Wiley |
| locations[3].landing_page_url | https://cris.maastrichtuniversity.nl/en/publications/c2edc6f7-cbc7-4f74-a4b7-e70fecfacede |
| indexed_in | crossref, pubmed |
| authorships[0].author.id | https://openalex.org/A5083096834 |
| authorships[0].author.orcid | https://orcid.org/0000-0002-9149-7483 |
| authorships[0].author.display_name | Pandichelvam Veeraiah |
| authorships[0].countries | NL |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I34352273 |
| authorships[0].affiliations[0].raw_affiliation_string | Department of Radiology and Nuclear Medicine, Maastricht University Medical Center, Maastricht, The Netherlands |
| authorships[0].institutions[0].id | https://openalex.org/I34352273 |
| authorships[0].institutions[0].ror | https://ror.org/02jz4aj89 |
| authorships[0].institutions[0].type | education |
| authorships[0].institutions[0].lineage | https://openalex.org/I34352273 |
| authorships[0].institutions[0].country_code | NL |
| authorships[0].institutions[0].display_name | Maastricht University |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Pandichelvam Veeraiah |
| authorships[0].is_corresponding | False |
| authorships[0].raw_affiliation_strings | Department of Radiology and Nuclear Medicine, Maastricht University Medical Center, Maastricht, The Netherlands |
| authorships[1].author.id | https://openalex.org/A5057207840 |
| authorships[1].author.orcid | |
| authorships[1].author.display_name | Kim Brouwers |
| authorships[1].countries | NL |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I34352273 |
| authorships[1].affiliations[0].raw_affiliation_string | Department of Radiology and Nuclear Medicine, Maastricht University Medical Center, Maastricht, The Netherlands |
| authorships[1].institutions[0].id | https://openalex.org/I34352273 |
| authorships[1].institutions[0].ror | https://ror.org/02jz4aj89 |
| authorships[1].institutions[0].type | education |
| authorships[1].institutions[0].lineage | https://openalex.org/I34352273 |
| authorships[1].institutions[0].country_code | NL |
| authorships[1].institutions[0].display_name | Maastricht University |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Kim Brouwers |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | Department of Radiology and Nuclear Medicine, Maastricht University Medical Center, Maastricht, The Netherlands |
| authorships[2].author.id | https://openalex.org/A5038435823 |
| authorships[2].author.orcid | https://orcid.org/0000-0002-4810-6854 |
| authorships[2].author.display_name | Joachim E. Wildberger |
| authorships[2].countries | NL |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I34352273 |
| authorships[2].affiliations[0].raw_affiliation_string | Department of Radiology and Nuclear Medicine, Maastricht University Medical Center, Maastricht, The Netherlands |
| authorships[2].institutions[0].id | https://openalex.org/I34352273 |
| authorships[2].institutions[0].ror | https://ror.org/02jz4aj89 |
| authorships[2].institutions[0].type | education |
| authorships[2].institutions[0].lineage | https://openalex.org/I34352273 |
| authorships[2].institutions[0].country_code | NL |
| authorships[2].institutions[0].display_name | Maastricht University |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Joachim E. Wildberger |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | Department of Radiology and Nuclear Medicine, Maastricht University Medical Center, Maastricht, The Netherlands |
| authorships[3].author.id | https://openalex.org/A5070391533 |
| authorships[3].author.orcid | https://orcid.org/0000-0001-7795-584X |
| authorships[3].author.display_name | Vera B. Schrauwen‐Hinderling |
| authorships[3].countries | NL |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I34352273 |
| authorships[3].affiliations[0].raw_affiliation_string | Department of Radiology and Nuclear Medicine, Maastricht University Medical Center, Maastricht, The Netherlands |
| authorships[3].affiliations[1].institution_ids | https://openalex.org/I34352273 |
| authorships[3].affiliations[1].raw_affiliation_string | Department of Nutrition and Movement Sciences, Maastricht University, Maastricht, The Netherlands |
| authorships[3].institutions[0].id | https://openalex.org/I34352273 |
| authorships[3].institutions[0].ror | https://ror.org/02jz4aj89 |
| authorships[3].institutions[0].type | education |
| authorships[3].institutions[0].lineage | https://openalex.org/I34352273 |
| authorships[3].institutions[0].country_code | NL |
| authorships[3].institutions[0].display_name | Maastricht University |
| authorships[3].author_position | middle |
| authorships[3].raw_author_name | Vera B. Schrauwen‐Hinderling |
| authorships[3].is_corresponding | True |
| authorships[3].raw_affiliation_strings | Department of Nutrition and Movement Sciences, Maastricht University, Maastricht, The Netherlands, Department of Radiology and Nuclear Medicine, Maastricht University Medical Center, Maastricht, The Netherlands |
| authorships[4].author.id | https://openalex.org/A5016797998 |
| authorships[4].author.orcid | https://orcid.org/0000-0002-3857-5024 |
| authorships[4].author.display_name | Lucas Lindeboom |
| authorships[4].countries | NL |
| authorships[4].affiliations[0].institution_ids | https://openalex.org/I34352273 |
| authorships[4].affiliations[0].raw_affiliation_string | Department of Radiology and Nuclear Medicine, Maastricht University Medical Center, Maastricht, The Netherlands |
| authorships[4].affiliations[1].institution_ids | https://openalex.org/I34352273 |
| authorships[4].affiliations[1].raw_affiliation_string | Department of Nutrition and Movement Sciences, Maastricht University, Maastricht, The Netherlands |
| authorships[4].institutions[0].id | https://openalex.org/I34352273 |
| authorships[4].institutions[0].ror | https://ror.org/02jz4aj89 |
| authorships[4].institutions[0].type | education |
| authorships[4].institutions[0].lineage | https://openalex.org/I34352273 |
| authorships[4].institutions[0].country_code | NL |
| authorships[4].institutions[0].display_name | Maastricht University |
| authorships[4].author_position | last |
| authorships[4].raw_author_name | Lucas Lindeboom |
| authorships[4].is_corresponding | False |
| authorships[4].raw_affiliation_strings | Department of Nutrition and Movement Sciences, Maastricht University, Maastricht, The Netherlands, Department of Radiology and Nuclear Medicine, Maastricht University Medical Center, Maastricht, The Netherlands |
| has_content.pdf | True |
| has_content.grobid_xml | True |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mrm.28394 |
| open_access.oa_status | hybrid |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | Application of a BIlinear Rotation Decoupling (BIRD) filter in combination with J‐difference editing for indirect 13C measurements in the human liver |
| has_fulltext | True |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T10378 |
| primary_topic.field.id | https://openalex.org/fields/27 |
| primary_topic.field.display_name | Medicine |
| primary_topic.score | 0.9998000264167786 |
| primary_topic.domain.id | https://openalex.org/domains/4 |
| primary_topic.domain.display_name | Health Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/2741 |
| primary_topic.subfield.display_name | Radiology, Nuclear Medicine and Imaging |
| primary_topic.display_name | Advanced MRI Techniques and Applications |
| related_works | https://openalex.org/W2031586312, https://openalex.org/W3174913151, https://openalex.org/W2157355069, https://openalex.org/W2069460318, https://openalex.org/W2333960626, https://openalex.org/W2081056453, https://openalex.org/W2004159752, https://openalex.org/W3126889494, https://openalex.org/W2021792849, https://openalex.org/W2156260160 |
| cited_by_count | 6 |
| counts_by_year[0].year | 2023 |
| counts_by_year[0].cited_by_count | 1 |
| counts_by_year[1].year | 2022 |
| counts_by_year[1].cited_by_count | 2 |
| counts_by_year[2].year | 2021 |
| counts_by_year[2].cited_by_count | 2 |
| counts_by_year[3].year | 2020 |
| counts_by_year[3].cited_by_count | 1 |
| locations_count | 4 |
| best_oa_location.id | doi:10.1002/mrm.28394 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S111160002 |
| best_oa_location.source.issn | 0740-3194, 1522-2594 |
| best_oa_location.source.type | journal |
| best_oa_location.source.is_oa | False |
| best_oa_location.source.issn_l | 0740-3194 |
| best_oa_location.source.is_core | True |
| best_oa_location.source.is_in_doaj | False |
| best_oa_location.source.display_name | Magnetic Resonance in Medicine |
| best_oa_location.source.host_organization | https://openalex.org/P4310320595 |
| best_oa_location.source.host_organization_name | Wiley |
| best_oa_location.source.host_organization_lineage | https://openalex.org/P4310320595 |
| best_oa_location.source.host_organization_lineage_names | Wiley |
| best_oa_location.license | cc-by-nc-nd |
| best_oa_location.pdf_url | https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mrm.28394 |
| best_oa_location.version | publishedVersion |
| best_oa_location.raw_type | journal-article |
| best_oa_location.license_id | https://openalex.org/licenses/cc-by-nc-nd |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | True |
| best_oa_location.raw_source_name | Magnetic Resonance in Medicine |
| best_oa_location.landing_page_url | https://doi.org/10.1002/mrm.28394 |
| primary_location.id | doi:10.1002/mrm.28394 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S111160002 |
| primary_location.source.issn | 0740-3194, 1522-2594 |
| primary_location.source.type | journal |
| primary_location.source.is_oa | False |
| primary_location.source.issn_l | 0740-3194 |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | False |
| primary_location.source.display_name | Magnetic Resonance in Medicine |
| primary_location.source.host_organization | https://openalex.org/P4310320595 |
| primary_location.source.host_organization_name | Wiley |
| primary_location.source.host_organization_lineage | https://openalex.org/P4310320595 |
| primary_location.source.host_organization_lineage_names | Wiley |
| primary_location.license | cc-by-nc-nd |
| primary_location.pdf_url | https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mrm.28394 |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | https://openalex.org/licenses/cc-by-nc-nd |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | Magnetic Resonance in Medicine |
| primary_location.landing_page_url | https://doi.org/10.1002/mrm.28394 |
| publication_date | 2020-07-03 |
| publication_year | 2020 |
| referenced_works | https://openalex.org/W2147937603, https://openalex.org/W86204186, https://openalex.org/W2464846577, https://openalex.org/W2744665203, https://openalex.org/W1910025641, https://openalex.org/W2517487403, https://openalex.org/W2013281941, https://openalex.org/W2024337692, https://openalex.org/W2145396220, https://openalex.org/W2131059447, https://openalex.org/W2035865284, https://openalex.org/W2970782647, https://openalex.org/W4241067496 |
| referenced_works_count | 13 |
| abstract_inverted_index.1 | 98, 151, 192, 211 |
| abstract_inverted_index.C | 163 |
| abstract_inverted_index.a | 4, 43, 51, 65, 73, 109, 205 |
| abstract_inverted_index.12 | 194 |
| abstract_inverted_index.13 | 12, 19, 100, 153, 162, 177, 213, 242, 259 |
| abstract_inverted_index.3T | 107 |
| abstract_inverted_index.C. | 178 |
| abstract_inverted_index.C] | 101, 195 |
| abstract_inverted_index.In | 145 |
| abstract_inverted_index.MR | 116 |
| abstract_inverted_index.To | 90 |
| abstract_inverted_index.an | 253 |
| abstract_inverted_index.be | 169 |
| abstract_inverted_index.in | 14, 27, 34, 134, 136, 199, 223, 244, 262, 266 |
| abstract_inverted_index.is | 31, 132, 166, 252 |
| abstract_inverted_index.of | 36, 46, 64, 72, 94, 176, 182, 191, 208, 210, 230 |
| abstract_inverted_index.on | 106 |
| abstract_inverted_index.to | 17, 42, 60, 79, 168, 172, 204, 238 |
| abstract_inverted_index.us | 237 |
| abstract_inverted_index.we | 2, 58, 148 |
| abstract_inverted_index.50% | 47 |
| abstract_inverted_index.JDE | 67, 200 |
| abstract_inverted_index.The | 180, 249 |
| abstract_inverted_index.all | 245 |
| abstract_inverted_index.and | 120, 160, 255 |
| abstract_inverted_index.fat | 143 |
| abstract_inverted_index.for | 10, 258 |
| abstract_inverted_index.oil | 111 |
| abstract_inverted_index.our | 129 |
| abstract_inverted_index.the | 15, 23, 62, 70, 92, 95, 121, 150, 156, 173, 183, 188, 219, 228, 241, 263 |
| abstract_inverted_index.use | 71, 229 |
| abstract_inverted_index.1.1% | 170 |
| abstract_inverted_index.100% | 81, 209 |
| abstract_inverted_index.BIRD | 96, 122, 185, 231 |
| abstract_inverted_index.This | 29 |
| abstract_inverted_index.case | 35 |
| abstract_inverted_index.five | 137, 246 |
| abstract_inverted_index.from | 108, 155 |
| abstract_inverted_index.gain | 84, 207 |
| abstract_inverted_index.into | 22 |
| abstract_inverted_index.loss | 45 |
| abstract_inverted_index.more | 32 |
| abstract_inverted_index.pool | 26, 159 |
| abstract_inverted_index.tool | 257 |
| abstract_inverted_index.vivo | 135, 224 |
| abstract_inverted_index.were | 104, 225 |
| abstract_inverted_index.when | 48, 85, 216 |
| abstract_inverted_index.with | 50, 69, 87, 113, 125, 140, 218, 227, 233 |
| abstract_inverted_index.Here, | 57 |
| abstract_inverted_index.H‐[ | 99, 152, 193, 212 |
| abstract_inverted_index.Phase | 221 |
| abstract_inverted_index.based | 7 |
| abstract_inverted_index.human | 264 |
| abstract_inverted_index.leads | 41, 203 |
| abstract_inverted_index.lipid | 25, 102, 158, 196 |
| abstract_inverted_index.liver | 16, 142, 265 |
| abstract_inverted_index.these | 146 |
| abstract_inverted_index.three | 114 |
| abstract_inverted_index.track | 18 |
| abstract_inverted_index.vivo. | 28, 267 |
| abstract_inverted_index.which | 165, 202, 235 |
| abstract_inverted_index.(BIRD) | 77 |
| abstract_inverted_index.(JDE). | 56 |
| abstract_inverted_index.filter | 78, 97, 123, 186 |
| abstract_inverted_index.higher | 82 |
| abstract_inverted_index.intend | 59 |
| abstract_inverted_index.lipids | 21 |
| abstract_inverted_index.method | 8, 131 |
| abstract_inverted_index.peanut | 110 |
| abstract_inverted_index.robust | 33 |
| abstract_inverted_index.signal | 44, 83, 197, 206 |
| abstract_inverted_index.tested | 133 |
| abstract_inverted_index.C‐MRS | 13 |
| abstract_inverted_index.Methods | 89 |
| abstract_inverted_index.Purpose | 0 |
| abstract_inverted_index.Results | 179 |
| abstract_inverted_index.achieve | 80 |
| abstract_inverted_index.editing | 54 |
| abstract_inverted_index.enabled | 236 |
| abstract_inverted_index.healthy | 138 |
| abstract_inverted_index.hepatic | 24, 157 |
| abstract_inverted_index.improve | 61 |
| abstract_inverted_index.minimal | 226 |
| abstract_inverted_index.motion, | 38 |
| abstract_inverted_index.natural | 174 |
| abstract_inverted_index.quantum | 5 |
| abstract_inverted_index.reduces | 187 |
| abstract_inverted_index.regular | 66 |
| abstract_inverted_index.signals | 215 |
| abstract_inverted_index.spectra | 103 |
| abstract_inverted_index.varying | 141 |
| abstract_inverted_index.BIlinear | 74 |
| abstract_inverted_index.Finally, | 128 |
| abstract_inverted_index.Rotation | 75 |
| abstract_inverted_index.acquired | 105 |
| abstract_inverted_index.approach | 30 |
| abstract_inverted_index.artifact | 190 |
| abstract_inverted_index.compared | 49, 86, 217, 232 |
| abstract_inverted_index.content. | 144 |
| abstract_inverted_index.expected | 167 |
| abstract_inverted_index.however, | 39 |
| abstract_inverted_index.indirect | 11 |
| abstract_inverted_index.phantom, | 112 |
| abstract_inverted_index.proposed | 130, 184 |
| abstract_inverted_index.quantify | 240 |
| abstract_inverted_index.robustly | 239 |
| abstract_inverted_index.sequence | 251 |
| abstract_inverted_index.subjects | 147 |
| abstract_inverted_index.together | 124 |
| abstract_inverted_index.Recently, | 1 |
| abstract_inverted_index.abundance | 175 |
| abstract_inverted_index.according | 171 |
| abstract_inverted_index.coherence | 6 |
| abstract_inverted_index.determine | 91 |
| abstract_inverted_index.different | 115 |
| abstract_inverted_index.efficient | 254 |
| abstract_inverted_index.promising | 256 |
| abstract_inverted_index.subjects. | 247 |
| abstract_inverted_index.technique | 55 |
| abstract_inverted_index.C]‐lipid | 214 |
| abstract_inverted_index.Conclusion | 248 |
| abstract_inverted_index.Decoupling | 76 |
| abstract_inverted_index.determined | 161 |
| abstract_inverted_index.efficiency | 93 |
| abstract_inverted_index.ge‐HSQC, | 118 |
| abstract_inverted_index.ge‐HSQC. | 88, 220 |
| abstract_inverted_index.inherently | 40 |
| abstract_inverted_index.introduced | 3 |
| abstract_inverted_index.quantified | 149 |
| abstract_inverted_index.robustness | 63 |
| abstract_inverted_index.sequences: | 117 |
| abstract_inverted_index.volunteers | 139 |
| abstract_inverted_index.(ge‐HSQC) | 9 |
| abstract_inverted_index.C]‐signal | 154 |
| abstract_inverted_index.C‐labeled | 20 |
| abstract_inverted_index.application | 181 |
| abstract_inverted_index.distortions | 222 |
| abstract_inverted_index.efficiently | 198 |
| abstract_inverted_index.enrichment, | 164 |
| abstract_inverted_index.experiments | 261 |
| abstract_inverted_index.respiratory | 37 |
| abstract_inverted_index.subtraction | 189 |
| abstract_inverted_index.C‐tracking | 260 |
| abstract_inverted_index.STEAM‐ACED | 126 |
| abstract_inverted_index.conventional | 52 |
| abstract_inverted_index.experiments, | 201 |
| abstract_inverted_index.STEAM‐ACED, | 119, 234 |
| abstract_inverted_index.(STEAM‐ACED) | 68 |
| abstract_inverted_index.C‐enrichment | 243 |
| abstract_inverted_index.J‐difference | 53 |
| abstract_inverted_index.BIRD‐STEAM‐ACED | 250 |
| abstract_inverted_index.(BIRD‐STEAM‐ACED). | 127 |
| cited_by_percentile_year.max | 96 |
| cited_by_percentile_year.min | 89 |
| corresponding_author_ids | https://openalex.org/A5070391533 |
| countries_distinct_count | 1 |
| institutions_distinct_count | 5 |
| corresponding_institution_ids | https://openalex.org/I34352273 |
| citation_normalized_percentile.value | 0.73327163 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |