Arabinoxylan from Corn Fiber Obtained through Alkaline Extraction and Membrane Purification: Relating Bioactivities with the Phenolic Compounds Article Swipe
Verónica Weng
,
Martim Cardeira
,
Andreia Bento‐Silva
,
Teresa Serra
,
Carla Brazinha
,
Maria Rosário Bronze
·
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.3390/molecules28155621
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.3390/molecules28155621
Arabinoxylan has prebiotic properties, as it is able to resist digestion in the small intestine and undergoes fermentation in the large intestine. In this work, arabinoxylan was extracted from corn fiber using an alkaline solution and further purified with membrane processing. It was found that the extracts were mainly composed of xylose (50–52%), arabinose (37–39%), galactose (9%) and glucose (1–4%), with an A/X ratio of 0.72–0.77. All the extracts were composed of phenolic compounds, including ferulic acid derivatives such as dimers, trimers and tetramers. The purified extract had a lower concentration of ferulic and p-coumaric acid (0.004 and 0.02 mg/mgdry_weight, respectively) when compared to raw extract (19.30 and 2.74 mg/mgdry_weight, respectively). The same effect was observed for the antioxidant activity, with purified extracts having a lower value (0.17 ± 0.02 µmol TEAC/mg) when compared to the raw extract (2.20 ± 0.35 µmol TEAC/mg). The purified extract showed a greater antiproliferative effect against the HT29 cell line with EC50 = 0.12 ± 0.02 mg/mL when compared to the raw extract (EC50 = 5.60 ± 1.6 mg/mL). Both raw and purified extracts did not show any cytotoxicity to the Caco-2 cell line in the maximum concentration tested (10 mg/mL).
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.3390/molecules28155621
- https://www.mdpi.com/1420-3049/28/15/5621/pdf?version=1690255222
- OA Status
- gold
- Cited By
- 11
- References
- 27
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4385241724
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4385241724Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.3390/molecules28155621Digital Object Identifier
- Title
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Arabinoxylan from Corn Fiber Obtained through Alkaline Extraction and Membrane Purification: Relating Bioactivities with the Phenolic CompoundsWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2023Year of publication
- Publication date
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2023-07-25Full publication date if available
- Authors
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Verónica Weng, Martim Cardeira, Andreia Bento‐Silva, Teresa Serra, Carla Brazinha, Maria Rosário BronzeList of authors in order
- Landing page
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https://doi.org/10.3390/molecules28155621Publisher landing page
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https://www.mdpi.com/1420-3049/28/15/5621/pdf?version=1690255222Direct link to full text PDF
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YesWhether a free full text is available
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goldOpen access status per OpenAlex
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https://www.mdpi.com/1420-3049/28/15/5621/pdf?version=1690255222Direct OA link when available
- Concepts
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Arabinoxylan, Ferulic acid, Chemistry, Arabinose, Xylose, Chromatography, Fermentation, Food science, Extraction (chemistry), Antioxidant, Coumaric acid, EC50, Polysaccharide, Biochemistry, In vitroTop concepts (fields/topics) attached by OpenAlex
- Cited by
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11Total citation count in OpenAlex
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2025: 5, 2024: 4, 2023: 2Per-year citation counts (last 5 years)
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27Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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